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Case Comprehensive Cancer Center Newsletter

October 19, 2009


What You Don't Know Might Kill You
Newsweek - Oct 17, 2009
"Eighty percent of cancers can and should be treated in community settings," says urological surgeon Derek Raghavan of the Cleveland Clinic. ...

Case Western Reserve Receives $3.4 Million in Grants for Various Health Studies
Crain's Cleveland Business - Oct 16, 2009
James Basilion, an associate professor of radiology at CWRU, hopes to improve the accuracy of cancer surgery by exploiting the over-expression of enzymes ... Jeffrey Duerk, chairman of the Biomedical Engineering Department, will be able to hire an assistant professor to help coordinate efforts by his department, the Case Center for Imaging Research, the medical school and the Case Comprehensive Cancer Center.

Blood Vessel Builders
EurekAlert (press release) - October 13, 2009
Leading the project are Roger Marchant and Horst von Recum, professors of biomedical engineering at the Case School of Engineering. ...

CWRU Receives $20.5M From Dental School Grad
Crain's Cleveland Business - October 13, 2009
... funded the creation of the Dr. Donald and Ruth Goodman Professorship in Innovative Cancer Therapeutics, which is currently held by Dr. Mary Laughlin. ...


Michael Vogelbaum, MD, PhD, Associate Director of Cleveland Clinic's Brain Tumor and Neuro-Oncology Center, has been named the Robert W. and Kathryn B. Lamborn Chair for Neuro-Oncology. The Chair will provide financial support for brain cancer research and education.

Congratulations to the following Cancer Center members who were recently awarded small pilot funding to support studies conducted through the CTSC Core facilities: Mark Adams, PhD, Jill Barnholtz-Sloan, PhD, Ann-Marie Broome, PhD, Patrick Ma, MD, and James Swain, PhD.


On Thursday, October 15, the American Cancer Society held a luncheon to recognize local cancer researchers who had recently been awarded fellowships and grants.

Dr. Clark Distelhorst was recognized as the recipient of the Hero of Hope Research Medal of Honor. Since 2001, this award has recognized an individual who has made significant contributions to the field of cancer research. This year, Dr. Distelhorst was chosen especially for his commitment to furthering cancer research, and his role as an educator and mentor to the next generation of cancer researchers.

The following Cancer Center Members were also recognized at this event:

Ohio Division Supported Research Pilot Award Grantees
Donna Hansel, MD, PhD
Kurt Runge, PhD
Hisashi Tanaka, MD, PhD
Horst von Recum, PhD

National Extramural Grantees
Helene Bernstein, MD, PhD- Research Scholar Grant

Charis Eng, MD, PhD- Professor of Clinical Cancer Research

Gary Koski, PhD- Research Scholar Grant

Edward Stavnezer, PhD- Institutional Research Grant

Vivian von Gruenigen, MD- Research Scholar Grant in Psychological and Behavioral Research


We are always trying to foster communication and collaboration across the cancer center community any way that we can. The Case CCC has set up a page on Facebook and LinkedIn, so please become a fan of us on Facebook or join our group on LinkedIn, and encourage others to do so as well. Please help us spread the word.

We encourage you to post events, relevant news articles, items of discussion, etc… Your feedback is appreciated!

CALL FOR NOMINATIONS– AACR Future Leaders in Translational Research Special Symposium

The AACR Associate Member Council seeks institutional nominations of outstanding young investigators as speakers for the Future Leaders in Translational Research Special Symposium, to be held during the AACR 101st Annual Meeting, April 17-21, 2010, in Washington, DC.

Selected speakers will be invited to present a 25 minute platform presentation and will be introduced by a prominent senior researcher within their field. Selected candidates will be considered Invited Speakers at the Annual Meeting, receiving complimentary registration and reimbursement of eligible expenses related to meeting attendance.

Institutional nominations will be accepted from any cancer center director, dean, or other leader of any institution involved in cancer research, cancer medicine, or cancer-related biomedical science; such institutions include those within academia, industry, and government, anywhere in the world. Each institution may submit up to two nominees, who may be graduate students, medical students or residents, clinical fellows, or postdoctoral fellows. Junior faculty are not eligible for nomination, including trainees expected to advance to junior faculty status prior to the Symposium.

Please send your nominations to Gillian Irwin Todd (gillian.irwin@case.edu) ASAP.

Nomination Deadline: October 30

For more information, please click here.


The application cycle for the NIH extramural Loan Repayment Programs (LRPs) ends December 1. The extramural LRPs often allow scientific investigators to remain in the research workforce, achieve research independence, and focus their efforts on advancing the health of the nation without having to worry about their student loan debt. The extramural LRPs include Clinical Research, Pediatric Research, Health Disparities Research, Contraception and Infertility Research, and Clinical Research for Individuals from Disadvantaged Backgrounds.

Applicants must possess a doctoral-level degree (with the exception of the Contraception and Infertility Research LRP); be a US citizen, national, or permanent resident; devote 20 hours or more per week to conducting qualified research funded by a university, nonprofit organization, or federal, state, or local government entity; and have qualified educational loan debt equal to or exceeding 20 percent of their institutional base salary.

For details, please click here.

CALL FOR NOMINATIONS– Doris Duke Charitable Foundation Clinical Scientist Development Award

The Doris Duke Charitable Foundation is accepting nominations for the Clinical Scientist Development Award. This award provides grants to junior physician-scientists to facilitate their transition to independent clinical research careers. Each U.S. accredited, degree-granting institution, "which would encompass for that institution all affiliated graduate schools, related hospitals and research institutes", may nominate up to two candidates.

Nomination Deadline: November 17
Proposal Deadline: December 22

For more information, please click here.

FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position.

Click here to view the job description.

MARK YOUR CALENDARS– Breast Cancer Spotlight Series

Save the date for the next Breast Cancer Spotlight Series seminar, featuring Dr. William J. Muller, Professor of Biochemistry at McGill University. Dr. Muller will present Oncogene-Mediated Signaling in Transgenic Mouse Models of Human Breast Cancer. The seminar is scheduled for Tuesday, October 27 at 12:00 pm in SOM W331.

FUNDING OPPORTUNITY– Clinical Research Scholar Career Development Training Program

The Multidisciplinary Clinical Research Training Program seeks outstanding candidates to fill five Clinical Research (CR) Scholar positions available in July 2010. The training program is funded by the NIH and it is a component of the Cleveland Clinical and Translational Science Collaborative. This innovative program is a collaboration involving CWRU, Cleveland Clinic, UH and MetroHealth. Each CR Scholar will embark on a 4-year program of intensive training in multidisciplinary team-based, patient-oriented research, combining a novel educational program with mentored research experiences.

Interested applicants should contact Beth Spyke at spykeb@ccf.org or click here for further information and application instructions.

Deadline: October 23


**All events are open to anyone interested in attending

October 19

Hem/Onc Research in Progress Seminar cancelled

Pathology Research Seminar
Susann Brady-Kalnay, PhD
Associate Professor, Molecular Biology and Microbiology
Topic: Targeting PTPmu as a Molecular Diagnostic and Therapeutic for Glioblastomas
12:00 pm WRB 5-136

Tumor Signaling and Metastasis Focus Group Meeting
2:00 pm WRB 3-136

Skeletal Research Center Seminar
J. Michael Sorrell, PhD
Senior Research Associate, Biology
Topic: The Influence of Mesenchymal Stem Cells During Wound Repair
4:00 pm Millis 123

October 20

Immunology Seminar
Edward Medof, MD, PhD
Professor, Pathology
Topic: Lewis Pillemer Could Never Have Imagined It
12:00 pm WRB 1-413

Mission RNAi Tools: Effective Gene Silencing
Arumugham (Ragoo) Raghunathan, PhD
Senior Field Applications Specialist
Sigma-Aldrich R&D
Topic: Overcoming Limitations of Delivery, Robust Knock-Down, and Large Scale Screening
12:00 pm BRB 632

Developmental Therapeutics Program Meeting
5:00 pm WRB 2-136

October 21

Grand Rounds
Cecilia Choi, MD
Fellow, Division of Hem/Onc
Topic: Skeletal Complications of Breast, Prostate Cancer and Multiple Myeloma
8:00 am Lerner Tower B-151

Emerging Technologies in Biomedical Research Seminar
Norbert Perrimon, PhD
Professor, Genetics
Harvard Medical School
Topic: Tissue Culture and in vivo Genome-Wide RNAi: Methods and Applications
11:00 am WRB 1-413

Emerging Technologies in Biomedical Research Seminar
Norbert Perrimon, PhD
Professor, Genetics
Harvard Medical School
Topic: Muscle Growth and Remodeling During Drosophila Development
4:00 am WRB 1-413

October 22

Taussig Cancer Institute Core Curriculum Series
Matthew Kalaycio, MD
Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: CML
12:00 pm R3-002 Cleveland Clinic

Physiology & Biophysics Faculty Candidate
Vijay Kumar Yadav, PhD
Postdoctoral Fellow, Genetics and Development
Columbia University
Topic: Molecular and Genetic Dissection of Serotonin Regulation of Bone Mass
4:00 pm SOM E501

October 23

Cancer Center Seminar Series/ Blood Club cancelled

Hematology/ Oncology Fellows Conference
Paolo Caimi, MD
Fellow, Div. of Hem/Onc
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Oliver Sartor, MD
Professor, Cancer Research
Tulane University
Topic: Novel Approaches to Bone Target Therapy in Prostate Cancer
8:00 am R3/002-003A Cleveland Clinic

Cell Biology Seminar
Caroline Alexander, PhD
Associate Professor, Oncology
University of Wisconsin
Topic: Wnt Signaling and Mammary Stem Cells
10:00 am NC1-202 Cleveland Clinic


For a complete listing of LRI seminars click here.


Case CCC Scientific Series
November 5
4:00 pm - 7:00 pm WRB 1-413


Case Center for Proteomics and Bioinformatics Symposium
October 19
WRB 1-413

ICMS-AACR-INCa Fifth International Conference on Tumor Microenvironment: Progression, Therapy and Prevention
October 20-24
Palais des Congres de Versailles, Versailles, France

AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
November 15-19
John B. Hynes Veterans Memorial Convention Center, Boston, MA Details

AACR Seminar: Frontiers in Cancer Prevention Research
December 6-9
Houston, TX

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, AZ

AACR Eighth Annual International Conference on Frontiers in Cancer Prevention Research
December 6-9
Hilton Americas, Houston, TX

32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium
December 10-13
Henry B. Gonzalez Convention Center, San Antonio, TX

AACR Seminar: Genetics and Biology of Brain Cancers
December 13-15
Omni San Diego Hotel, San Diego, CA

AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy
January 11-14, 2010
Loews Coronado Bay Resort, Coronado, CA

AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
February 5-9, 2010
Hilton Waikoloa Village, Waikoloa, HI

AACR 101st Annual Meeting
April 17-21, 2010
Washington, DC


NIH Director's Pioneer Awards
Deadline: October 20

Clinical Research Scholar Career Development Training Program
Deadline: October 23

NIH Director's New Innovator Awards
Deadline: October 27

Pancreatic Cancer Action Network-AACR Career Development Awards
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Research Fellowship
Application Deadline: October 28

DOD BCRP Concept Award
Pre-Application Deadline: October 29
Proposal Deadline: November 12

ED Thomas Post Doctoral Fellowship 2009
Deadline: November 2

DOD BCRP Concept Award
Proposal Deadline: November 12

Komen Postdoctoral Fellowship Research (PDF) Grants
Full Application Deadline: November 17

Komen Post-Baccalaureate Training in Disparities Research (PBT-DR) Grants
Full Application Deadline: November 17

DOD Lung Cancer Research Program Clinical Fellow Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

Sidney Kimmel Foundation for Cancer Research Kimmel Scholar Award
Deadline: December 2

Sidney Kimmel Foundation for Cancer Research Kimmel Translational Science Award
Deadline: December 2

DOD OCRP Ovarian Cancer Academy Dean Award
Proposal Deadline: December 2

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
Full Application Deadline: December 3

DOD Lung Cancer Research Program Clinical Fellow Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Application Deadline: December 3

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

NIH Population Tracking Requirements for ARRA Awards (NOT-OD-10-003)

Amendment to the Institutional Eligibility Criteria for Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowships (NOT-OD-10-004)

Change of Expiration Date for PA-08-185: Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies using Cells, Tissues and Animal Models of Disease (R21) (NOT-AT-09-008)

Bioengineering Research Grants (BRG) (R01) (PA-10-009)

Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21] (PA-10-010)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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