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Case Comprehensive Cancer Center Newsletter

October 12, 2009


Retrovirus May Be at Root of Chronic Fatigue Syndrome
Atlanta Journal Constitution - Oct 8, 2009
... however it does suggest it is a viable candidate for a cause," said Robert H. Silverman, co-author of a report appearing online Oct. 8 in Science. ...

African American Lung Cancer Patients May Have Different Response To New Cancer Fighting Drugs
Science Daily (press release) - Oct 7, 2009
Published online in the Journal of Clinical Oncology, the study by Rom Leidner, MD, and colleagues report that ethnicity plays a significant role in ...... even individuals," says Stanton Gerson, MD, Director of the University Hospitals Ireland Cancer Center as well as the Case Comprehensive Cancer Center. ...


Patterns of Adaptation in Patients Living Long Term With Advanced Cancer
Cancer, Volume 115, Issue S18 (p 4298-4310)
Julia Rose, PhD, MA, Elizabeth O'Toole, PhD


The American Cancer Society Ohio Division has chosen Clark Distelhorst, MD to receive its distinguished John Peter Minton, MD, PhD, Hero of Hope Research Medal of Honor for his work in the area of Basic Research for 2009. Dr. Distelhorst will be recognized at a research celebration this Thursday.

Michael Vogelbaum, MD, PhD was elected as Secretary/ Treasurer of the Society for Neuro-Oncology.

Mark Jackson, PhD was recently awarded a Department of Defense Breast Cancer Research Program Idea Award.

MESSAGE FROM NEAL MEROPOL, MD– Division of Hem/Onc Publication Postings

Dr. Neal Meropol has placed a large cork board in Lakeside 1200 for posting of publications. Please tack up your recent papers, or email pdfs to Dr. Meropol's assistant, Mary Wright, and she will post them.


Featured Article
The Cancer Genome Atlas Project to Map 20 Tumor Types

Cancer Research Highlights
Hormone Therapy for Prostate Cancer May Pose Heart Risks

Breast Cancer Trial Suspends Recruitment

High-dose Daunorubicin Benefits Younger Adults with Leukemia

Many Survivors of Childhood Cancers Have Healthy Babies

Investigational Drug Effective Against Metastatic Melanoma in Early Phase Trial

Invasiveness of Breast Cancer Cells Linked to Two Proteins

Director's Update
Global Cancer Control: An Essential Duty


The Department of Defense (DOD) Breast Cancer Research Program (BCRP) has released the "Concept Awards" Program Announcement and is open for submissions. The Concept Award supports the exploration of a highly innovative new concept or untested theory that addresses an important problem relevant to breast cancer.

Pre-Application Deadline: October 29
Application Deadline: November 12

For more information, please click here.

FUNDING OPPORTUNITY– Doris Duke Charitable Foundation Clinical Scientist Development Award

The Doris Duke Charitbale Foundation is accepting nominations for the Clinical Scientist Development Award. This award provides grants to junior physician-scientists to facilitate their transition to independent clinical research careers. Each U.S. accredited, degree-granting institution, "which would encompass for that institution all affiliated graduate schools, related hospitals and research institutes", may nominate up to two candidates.

Nomination Deadline: November 17
Proposal Deadline: December 22

For more information, please click here.

MARK YOUR CALENDARS– Emerging Technologies in Biomedical Research: A Symposium Series

The Cell and Molecular Biology Training Program (CMBTP) is hosting the Emerging Technologies in Biomedical Research Symposium for the 2009-2010 school year. This seminar series highlights important technological advances in biomedical science including deep sequencing, high resolution fluorescence microscopy, and genome-wide functional screening. Six internationally renowned investigators have been invited and each will present two lectures - one focusing on the history and utility of the technology they are developing, and the second, a cutting edge research seminar highlighting recent advances made from their laboratories.

For more information about the symposium series, please click here.

FACULTY CANDIDATE SEARCH– Associate Director for Basic Research

The Case CCC is currently accepting applications for the position of Associate Director for Basic Research. As we continue our search, we ask that people in the Cancer Center community encourage any qualified candidate to apply for the position.

Click here to view the job description.

MARK YOUR CALENDARS– Breast Cancer Spotlight Series

Save the date for the next Breast Cancer Spotlight Series seminar, featuring Dr. William J. Muller, Professor of Biochemistry at McGill University. Dr. Muller will present Oncogene-Mediated Signaling in Transgenic Mouse Models of Human Breast Cancer. The seminar is scheduled for Tuesday, October 27 at 12:00 pm in SOM W331.

MARK YOUR CALENDARS– Lisa's Legacy 5K Run/Walk

The inaugural Lisa's Legacy 5K Run/Walk is on Sunday, October 18. The walk will begin at 8:30 am in the University Circle area, starting and finishing at the Museum of Natural History. Proceeds will benefit Lisa's Legacy Fund for Cancer Research and Education at ICC.

For more information and to register, please click here.

FUNDING OPPORTUNITY– Clinical Investigator Development Program

The Center for Cancer Research (CCR) announces a training opportunity for physicians interested in dedicating their careers to clinical oncology research. The Clinical Investigator Development Program will link eligible clinicians to a vibrant, multidisciplinary research community of more than 250 talented CCR intramural scientists conducting cutting-edge research on the campuses of the National Institutes of Health (NIH) in Bethesda and Frederick, Maryland. The CCR is nationally recognized as a premier training ground for clinical research, which is conducted in the state-of-the-art Clinical Research Center.

Application Deadline: October 15

Please click here for more information.

FUNDING OPPORTUNITY– Sidney Kimmel Foundation for Cancer Research

Kimmel Scholar Award
Qualified applicants must hold an MD, PhD or equivalent graduate degree and must perform research in an American not-for-profit institution during the period of Kimmel Foundation support. The Kimmel Foundation is seeking accomplished young investigators dedicated to a career in cancer research. Applications are limited to those who achieved the equivalent rank of Assistant Professor on or after July, 2006. However, physicians who have both clinical and research responsibility are eligible if appointed on or after July, 2005. These awards are designed for researchers who do not yet have their own R01 funding. Applicants will be judged on the basis of quality of prior work, research proposed and letters of support.

Kimmel Translational Science Award
The Foundation provides up to five additional awards specifically for physicians engaged in translational science. Eligibility includes those with M.D. or equivalent degrees, who have achieved the rank of Assistant Professor on or after July, 2005. Candidates must not hold R01 funding for the laboratory component of their cancer research. Applicants must demonstrate a significant personal involvement in the laboratory component of the translational project described. The translational research may involve primarily animal studies but must include reasonable application to subsequent human investigation.

Deadline: December 2

For more information, please click here.

FUNDING OPPORTUNITY– Clinical Research Scholar Career Development Training Program

The Multidisciplinary Clinical Research Training Program seeks outstanding candidates to fill 5 Clinical Research (CR) Scholar positions available in July 2010. The training program is funded by the NIH and it is a component of the Cleveland Clinical and Translational Science Collaborative. This innovative program is a collaboration involving CWRU, Cleveland Clinic, UH and MetroHealth. Each CR Scholar will embark on a 4-year program of intensive training in multidisciplinary team-based, patient-oriented research, combining a novel educational program with mentored research experiences.

Interested applicants should contact Beth Spyke at spykeb@ccf.org or click here for further information and application instructions.

Deadline: October 23


**All events are open to anyone interested in attending

October 12

Genetics and TREC Seminar
David Schlessinger, PhD
Chief, Laboratory of Genetics
NIH, National Institute on Aging
Topic: Fulfilling the Promise of Population Genetics Analyses in Sardinia
12:00 pm BRB 732

Hem/Onc Research in Progress Seminar
Snehal Dabir
Postdoc, Dowlati Lab
Division of Hematology/Oncology
Topic: Association and Nuclear Translocation of P1AS-3-STAT3 Complex is Ligand and Time Dependent: Crucial Role for Tyrosine 705 Phosphorylation
12:00 pm WRB 2-136

Pathology Dissertation Defense
Jennifer Ko
Graduate Student, Finke Lab, Pathology
Topic: Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cells in Cancer
12:00 pm WRB 1-413

Sequencing Data Interest Group (SDIG)
Xiaodong Bai, PhD
Postdoctoral Researcher, Entomology
Ohio State University
Topic: An Introduction to ChIP-Seq Data Analysis
2:30 pm WRB 1-413

Physiology & Biophysics Seminar
Junichi Sadoshima, MD, PhD
Professor and Vice Chair, Cell Biology and Molecular Medicine
University of Medicine and Dentistry of New Jersey
Topic: Redox Regulation of Cardiac Hypertrophy
4:00 pm SOM E501

October 13

Immunology Seminar
David Farrar, PhD
Assistant Professor, Immunology
UT Southwestern Medical Center
Topic: Type 1 Interferon: A Memory Booster for T cells
12:00 pm WRB 1-413

Taussig Cancer Institute Core Curriculum Series
Andrew Stephenson, MD
Assistant Professor, Urology
CWRU/ Cleveland Clinic
Topic: Localized Prostate Cancer
12:00 pm R3-002 Cleveland Clinic

October 14

Grand Rounds
Randy Harmatz
Vice President, Quality Center
Topic: Introduction to Quality
8:00 am Lerner Tower B-151

Molecular Genetics Seminar
Blossom Damania, PhD
Associate Professor, Microbiology and Immunology
University of North Carolina
Topic: KSHV: Oncogenesis and Immune Evasion
1:30 pm NE1-205 Cleveland Clinic

CSCRM Seminar
Debra Grega, PhD
Executive Director
Michael Gilkey, MBA, MS
Marketing and Operations Manager
Topic: Center for Stem Cell and Regenerative Medicine: Who We Are and How We Can Help You
4:30 pm LRI NA3-57 Cleveland Clinic

October 15

Inaugural Angie Fowler Lecture in Adolescent & Young Adult Oncology
Heidi Adams
Founder and Executive Director
Planet Cancer
John Letterio, MD
Professor, Pediatric Hematology/Oncology
Topic: Young Adults & Cancer: When Two Worlds Collide
8:00 am Rainbow Amphitheatre

Taussig Cancer Institute Core Curriculum Series
Robert Dreicer, MD
Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: Systemic Chemotherapy for Advanced Prostate Cancer
12:00 pm R3-002 Cleveland Clinic

October 16

Cancer Center Seminar Series/ Blood Club cancelled

Hematology/ Oncology Fellows Conference
Alvin Schmaier, MD
Professor, Medicine- Hem/Onc
Topic: Anticoagulation
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Sagar Lonial, MD
Assistant Professor, Hematology/ Oncology
Emory University
Topic: New Approaches and Options in Myeloma Therapy
8:00 am R3/002-003 Cleveland Clinic

2nd Annual Adolescent & Young Adult (AYA) Cancer Symposium
9:30 am - 12:00 pm WRB 1-413

Cell Biology Seminar
Jeffrey Segall, PhD
Professor, Anatomy & Structural Biology
Albert Einstein College of Medicine
Topic: Contributions of EFG Receptor Family Members to Breast Cancer Invasion and Metastasis
10:00 am NC1-202 Cleveland Clinic


For a complete listing of LRI seminars click here.


Case CCC Scientific Series
November 5
4:00 pm - 7:00 pm WRB 1-413


Breast Cancer, Sexuality and You
October 12
5:30 pm
Independence Civic Center

AACR Seminar: Advances in Breast Cancer Research
October 13-16
Hyatt Regency Mission Bay Spa and Marina, San Diego, CA

International Association for Comparative Research on Leukemia and Related Diseases (IACRLRD) Symposium XXIV
October 14-16
Ohio State University Comprehensive Cancer Center, Columbus, OH

Case Center for Proteomics and Bioinformatics Symposium
October 19
WRB 1-413

ICMS-AACR-INCa Fifth International Conference on Tumor Microenvironment: Progression, Therapy and Prevention
October 20-24
Palais des Congres de Versailles, Versailles, France

AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
November 15-19 John B. Hynes Veterans Memorial Convention Center, Boston, MA Details

AACR Seminar: Frontiers in Cancer Prevention Research
December 6-9
Houston, TX

Radiological Society of North America (RSNA) Clinical Trials Methodology Workshop
January 9 -15, 2010
Scottsdale, AZ

AACR Eighth Annual International Conference on Frontiers in Cancer Prevention Research
December 6-9
Hilton Americas, Houston, TX

32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium
December 10-13
Henry B. Gonzalez Convention Center, San Antonio, TX

AACR Seminar: Genetics and Biology of Brain Cancers
December 13-15
Omni San Diego Hotel, San Diego, CA

AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Prospects for Personalized Prevention and Therapy
January 11-14, 2010
Loews Coronado Bay Resort, Coronado, CA

AACR-JCA 8th Joint Conference on Cancer Genomics, Epigenomics, and the Development of Novel Therapeutics
February 5-9, 2010
Hilton Waikoloa Village, Waikoloa, HI

AACR 101st Annual Meeting
April 17-21, 2010
Washington, DC


Clinical Investigator Development Program
Application Deadline: October 15

ACS Postdoctoral Fellowships
Deadline: October 15

NIH Director's Pioneer Awards
Deadline: October 20

Clinical Research Scholar Career Development Training Program
Deadline: October 23

NIH Director's New Innovator Awards
Deadline: October 27

Pancreatic Cancer Action Network-AACR Career Development Awards
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant
Application Deadline: October 28

Pancreatic Cancer Action Network-AACR Research Fellowship
Application Deadline: October 28

DOD BCRP Concept Award
Pre-Application Deadline: October 29
Proposal Deadline: November 12

ED Thomas Post Doctoral Fellowship 2009
Deadline: November 2

DOD BCRP Concept Award
Proposal Deadline: November 12

Komen Postdoctoral Fellowship Research (PDF) Grants
Full Application Deadline: November 17

Komen Post-Baccalaureate Training in Disparities Research (PBT-DR) Grants
Full Application Deadline: November 17

DOD Lung Cancer Research Program Clinical Fellow Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Pre-Application Deadline: November 19
Application Deadline: December 3

DOD OCRP Ovarian Cancer Academy Dean Award
Proposal Deadline: December 2

ASCO Improving Cancer Care Grant Improving Cancer Care Grant (ICCG)
Full Application Deadline: December 3

DOD Lung Cancer Research Program Clinical Fellow Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Collaborative Translational Research Award
Application Deadline: December 3

DOD Lung Cancer Research Program Lung Cancer Promising Clinician Research Award
Application Deadline: December 3

DOD PRCRP Synergistic Idea Awards
Proposal Deadline: December 9

DOD PRCRP Collaborative Translational Science Awards
Proposal Deadline: December 9

DOD PRCRP Idea Awards
Proposal Deadline: December 9

DOD PRCRP Mentor-Predoctoral Fellow Research Awards
Proposal Deadline: December 9

DOD PRCRP New Investigator Awards
Proposal Deadline: December 9

AACR Scholar-in-Training Awards - Special Conferences
Deadline varies

NCI Short-Term Scientist Exchange Program
Deadline: Open

James S. McDonnell Foundation
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Request for Information (RFI): Studying the Roles of Cancer Stem Cells in Cancer Health Disparities (NOT-CA-10-001)

Request for Information (RFI): Oncometabolomics for Application in Cancer Detection, Prevention and Cancer Health Disparities (NOT-CA-10-002)

Cancer Nanotechnology Training Centers (CNTCs) (R25) (RFA-CA-09-014)

Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00) (RFA-CA-09-015)

Community Networks Program (CNP) – Centers for Reducing Cancer Disparities through Outreach, Research and Training (U54) RFA-CA-09-032

Mechanisms, Models, Measurement, and Management in Pain Research (R01) (PA-10-006)

Mechanisms, Models, Measurement, & Management in Pain Research (R21) (PA-10-007)

Mechanisms, Models, Measurement, and Management in Pain Research (R03) (PA-10-008)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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