Case Comprehensive Cancer Center Newsletter

January 5, 2009


On January 8, 2009 we are initiating a new Cancer Center Scientific Series. These occasional extended conferences will feature recent scientific investigation from our members, starting with presentations by investigators who received pilot funding after competitive peer review by the Cancer Center.

The presentations on January 8 will be made by three of the investigators who were awarded pilot project research funding for their studies in cancer imaging. This effort, begun in 2006, has helped to spawn a new scientific program in Cancer Imaging, led by Jim Basilion, PhD and Jeff Duerk, PhD. I would like to applaud the efforts of everyone involved in the Cancer Imaging Program for their involvement in cancer research and in the Cancer Center. These studies are highly interactive between experts in the technology of cellular and tumor imaging and cancer biologists. The following presentations on January 8 will reflect these collaborative efforts:

Susann Brady-Kalnay, PhD
Imaging Glioblastomas Using Probes that Detect the Receptor Protein Tyrosine Phosphatase mu

Chris Flask, PhD
Development of PARACEST-MRI Imaging Agents for in vivo Assessment of Autophagy

Yanming Wang, PhD
In vivo Quantification of DNA Damages in Cancer Chemotherapies

Please join us for this exciting program that begins at 4:00 pm in the Wolstein Auditorium. For those of you who will come over for the seminar, parking validation will be gladly provided. A reception will follow the presentations at approximately 5:45 pm. I hope to see you there!

Stan Gerson, MD
Director, Case CCC


The Case Comprehensive Cancer Center is pleased to recognize Kevin Bunting, PhD as Program Leader of the Year 2008.

Dr. Bunting has actively coordinated the diverse membership of the Stem Cells and Hematologic Malignancies scientific program, organized retreats and monthly meetings of program focused groups, and has participated in and developed research focus areas in leukemogenesis, stem cell biology, graft versus host disease, and hematologic malignancies. He has also served as a mentor to associate members and helped to bring them into the program.

These attributes reflect the prized efforts of program leadership for the Case Comprehensive Cancer Center.

FUNDING OPPORTUNITY– Jane Coffin Childs Memorial Fund

The Jane Coffin Childs Memorial Fund for Medical Research is currently accepting applications for fellowships, to be awarded to suitably qualified individuals for full time postdoctoral studies in the medical and related sciences bearing on cancer. Applicants in general should not have more than one year of postdoctoral experience. They must hold either an MD or PhD in the field in which they propose to study or furnish evidence of equivalent training and experience.

Deadline: February 1

For more information, please click here.


The Lasker Foundation is accepting applications for the following awards:

Albert Lasker Basic Medical Research Award
This Award honors scientists who have made fundamental investigations that open new areas of biomedical science.

Lasker-DeBakey Clinical Medical Research Award
This Award honors scientists whose contributions, directly or indirectly, have led in a pioneering way to a major improvement in the clinical management or treatment of patients.

Lasker-Koshland Special Achievement Award in Medical Science
This Award honors scientists whose contributions to research are of unique magnitude, and whose professional career has engendered within the biomedical community the deepest feelings of awe and respect. Scientists who have previously won a Lasker Award are ineligible for this Award.

Application Deadline: February 2

For more information, please click here.

FUNDING OPPORTUNITY– American Institute for Cancer Research

The American Institute for Cancer Research is accepting applications for Research Grant funding. The AICR Research Grant Program encourages innovative research on food, nutrition, physical activity and weight management in relation to cancer prevention, treatment and survivorship.

Investigator Initiated Grants (IIG)
AICR's Investigator Initiated Grant program remains the core of the Institute's research efforts. This program has contributed to a deeper and more precise understanding of how food, nutrition, physical activity and weight management impact the cancer process. It also encourages new research on dietary means of preventing and treating cancer or improving the life of the cancer patient and the cancer survivor. Research supported by this program uncovers the mechanisms by which nutrients and other food constituents help prevent or promote the cancer process.

Post-Doctoral Grant Awards (PDA)
AICR's Post-Doctoral Grant Awards are designed to encourage new researchers to enter the field of nutrition-cancer research and to explore innovative research ideas that are often difficult or impossible to fund from traditional sources.

Matching Grants (MG)
AICR is interested in working with for-profit corporations and/or non-profit organizations in funding cancer research consistent with AICR's areas of interest as outlined on pages 3–4. Research must be conducted at an academic or other non-profit research institution. AICR usually provides up to $75,000 as its part of the funding arrangement. Interested investigators should contact AICR to discuss application procedures. Applications will be evaluated by a peer review process and must meet the same high and rigorous standards as all other AICR funded grants.

Deadline: February 16

For details, please click here.


Enrollment is currently open for the following Cancer Biology courses: David Danielpour, PhD will be teaching Basic Cancer Biology and the Interface with Clinical Oncology: PHRM 520/ PATH 520, a graduate-level introductory course in cancer biology taught through the Departments of Pharmacology and Pathology. This course will give students a broad overview of current basic cancer biology, highlight recent advances in cancer therapeutics, and provide a clinical perspective of the pathogenesis and treatment of common cancers. Drs. Danielpour and Joseph Bokar, MD, PhD will be teaching Clinical Interface to Cancer Biology Conference PHRM521/ PATH521, a conference-based enrichment course of PHRM 520/PATH520, taken concurrently with PHRM520/ PATH520 or the following Spring Semester.

Details can be found at:
PHRM520/ PATH520 Course Overview
PHRM520/ PATH520 Class Schedule
PHRM521/ PATH521Course Overview

MARK YOUR CALENDARS– Weekly Seminar Series on Applied Biostatistics in Clinical Research

Mark Schluchter, PhD will be teaching a weekly seminar series on Applied Biostatistics in Clinical Research, sponsored by W.T. Dahms Clinical Research Unit and the Cleveland Clinical and Translational Sciences Collaborative (CTSC). The seminars will run Mondays from 4:00 pm - 5:30 pm in School of Medicine E501, January 12– March 9.

Online registration is open. To register and for more information, click here. For questions about the course, please contact Dr. Schluchter at

CALL FOR PAPERS– Ohio Collaborative Conference on Bioinformatics (OCCBIO)

The 4th Annual Ohio Collaborative Conference on Bioinformatics (OCCBIO 2009) will be held at CWRU June 15-17, 2009. The conference provides an interdisciplinary forum for the discussion of methods, research findings, and experiences in the area of Bioinformatics and Computational Biology. An important goal of the conference is to foster long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology that benefit Ohio.

OCCBIO invites researchers in the broad area of bioinformatics to submit their unpublished work to the conference. The conference proceedings will be indexed.

Papers will be accepted through January 27.

For details, please click here.


**All events are open to anyone interested in attending

January 5

Hematology/Oncology Research In Progress Seminar
Kristy Miskimen
Postdoc, Bunting Lab
Div. of Hematology/Oncology
Topic: Role of Gab Adapter Proteins in Normal and Leukemic Hematopoiesis
12:00 pm WRB 2-136

Physiology & Biophysics Seminar
Paul Janssen, PhD
Associate Professor, Physiology & Cell Biology and Internal Medicine- Cardiology
Ohio State University
Topic: Dynamic Aspects of Myocardial Relaxation
4:00 pm SOM E501

January 6

January 7

Grand Rounds
Sanford Markowitz, MD, PhD
Professor, Medicine- Hem/Onc
Topic: Colon Cancer Genetics
8:00 am Lerner Tower B-151

January 8

Neurosciences Seminar
Matthias Buck, PhD
Assistant Professor, Physiology & Biophysics
Topic: In Vitro Fun With Plexin and Eph Receptors: What Can Structural Biology/Protein Biophysics Tell Us About Their Signaling Mechanism in Axon Guidance?
12:10 pm BRB 105

Aging-Cancer Research Seminar
Linda Francis, PhD
PREP Fellow
Senior Research Associate, Medicine
CWRU/ MetroHealth
Topic: Relationship Quality, Anxiety and Burden among Family Caregivers of Late Stage Cancer Patients
4:00 pm BRB 732

Cancer Center Scientific Series: Imaging Pilot Projects
Susann Brady-Kalnay, PhD
Associate Professor, Molecular Biology & Microbiology
Topic: Imaging Glioblastomas Using Probes that Detect the Receptor Protein Tyrosine Phosphatase mu
Chris Flask, PhD
Assistant Professor, Radiology
Topic: Development of PARACEST-MRI Imaging Agents for in vivo Assessment of Autophagy
Yanming Wang, PhD
Associate Professor, Radiology
Topic In vivo Quantification of DNA Damages in Cancer Chemotherapies
4:00 pm - 6:00 pm WRB Auditorium
Reception to immediately follow

January 9

Hematology/ Oncology Fellows Seminar
Evi Stavrou, MD
Fellow, Div. of Hem/Onc
Topic: Fibrinogen Structure, Fibrinopeptides A/B and Thrombosis
8:00 am Wearn 137

Cancer Center Seminar Series/ Blood Club
Irving Weissman, MD
Professor, Clinical Investigation in Cancer Research
Director, Institute of Stem Cell Biology and Regenerative Medicine
Stanford Cancer Center
Topic: Normal & Neoplastic Stem Cells
12:00 pm BRB 105


For a complete listing of LRI seminars click here.



Emerging Trends in Cancer Immunotherapy
February 18
Holiday Inn, Independence
Course Directors: Drs. Henry Koon, Joseph Baar, Andrew Sloan
Details to follow

Family-Centered Care
March 21
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17
Holiday Inn, Independence
Details to follow

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17
CWRU campus
For details, click here.

Annual Breast Cancer Update: Highlights of the National Meetings
June 19
Marriott Cleveland East, Warrensville Heights
Details to follow

Case CCC Scientific Retreat 2009
July 10-11
Details to follow

**For more information on these symposiums, please contact Christine Rhoads.

MARK YOUR CALENDARS– Case CCC Basic Science Faculty Candidate Seminar

Case CCC Basic Science Faculty Candidate Hongwu Zheng, PhD will be giving a seminar on Monday, January 12 at 4:00 pm in Wolstein Research Building 1402. Dr. Zheng, a Post-Doc Research Fellow at the Dana Farber Cancer Institute/ Harvard Medical School, will be presenting Understanding Glioma Pathogenesis. All are encouraged to attend.

MARK YOUR CALENDARS– Case CCC Basic Science Faculty Candidate Presentations

Please mark your calendars for the following Faculty Candidate presentations:

Candidate: Sang-Oh Yoon, PhD, Research Fellow, Department of Cell Biology, Harvard Medical School
Thursday, January 15
3:00 pm - 4:00 pm Wolstein Research Building 3-136
Topic: TBA

Chalk Talk:
Friday, January 16
2:00 pm - 3:00 pm Wolstein Research Building 3-136
Topic: TBA

Candidate: Hugh P. Cam, PhD, Postdoctoral Fellow, Center for Cancer Research, NCI/NIH
Tuesday, January 20
3:00 pm - 4:00 pm Wolstein Research Building 1402
Topic: Epigenetic Control and Genome Organization by RNAi and Transposon-derived Proteins

Chalk Talk:
Wednesday, January 21
3:30 pm - 5:00 pm Wolstein Research Building 1403
Topic: Epigenome Organization and Phenotypic Plasticity

FUNDING OPPORTUNITY– James S. McDonnell Foundation

The Foundation offers Collaborative Activity Awards to initiate interdisciplinary discussions on problems or issues, to help launch interdisciplinary research networks, or to fund communities of researchers/practitioners dedicated to developing new methods, tools, and applications of basic research to applied problems.

In each case the focus of the collaborative activity must meet the program guidelines for one of the following program areas:
–Bridging Brain, Mind, and Behavior
–Studying Complex Systems
–Brain Cancer Research

Applications are continuously accepted for these awards.

For more information, please click here.

MARK YOUR CALENDARS– Molecular Targets for Cancer Prevention Symposium

February 4-5
NIH Natcher Conference Center
Bethesda, Maryland

The Center for Cancer Research and the Division of Cancer Prevention at the National Cancer Institute are presenting Molecular Targets for Cancer Prevention Symposium on February 4-5, 2009 at the NIH Natcher Conference Center in Bethesda, Maryland. Evidence from both preclinical and clinical studies will provide an exciting forum for timely discussion and debate on the state-of-the-science, recent advances, and opportunities for discovery.

Registration Deadline: January 11

For more information, please click here.

MARK YOUR CALENDARS–2nd Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science

March 16–18, 2009
Bethesda North Marriott Hotel & Conference Center
Bethesda, MD

Human biospecimens are the foundation of the translational research that will transform patient care. The 2009 BRN Symposium: Advancing Cancer Research Through Biospecimen Science will focus on the significant impact of pre-analytical biospecimen variables on cancer research and molecular medicine. This promises to be a stimulating and informative three-day event that will feature interactive discussions and presentations about biospecimen quality and recent advances in biospecimen science.

Abstract Submission Deadline: February 9
Registration Deadline: February 17

For more information, please click here.


ASCO Advanced Clinical Research Awards
Deadline: January 8

Skin Diseases Research Center
Deadline: January 9

Goldhirsh Foundation Brain Tumor Research Awards Program
Initial Proposal Deadline: January 13
Full Proposal Deadline (invite only): April 21

Ovarian Cancer Research Program (OCRP)
Pre-Application Deadline: January 13
Application Deadline: January 27

AACR Career Development Awards for Pediatric Cancer Research
Deadline: January 13

ASCO Cancer Foundation IDEA Grants
Deadline: January 14

UICC Yamagiwa-Yoshida Memorial International Study Grants
Deadline: January 15

NIH Director's New Innovator Awards
Deadline: January 15

Komen/ ASCO Loan Repayment Program
Deadline: January 15

AACR Stand Up To Cancer
LOI Deadline: January 22
Application Deadline (invite only): May 15

ASCO Cancer Foundation Translational Research Professorship
Deadline: January 22

Ovarian Cancer Research Program (OCRP)
Deadline: January 27

Pfizer Oncology Clinical Fellowship Awards
Deadline: January 31

Pfizer Fellowship In Health Disparities
Deadline: January 31

Pfizer Visiting Professorships in Oncology
Deadline: January 31

Komen/ASCO Medical Student Rotation
Deadline: February 20

Komen/ASCO Resident Travel Award
Deadline: February 20

2009 NASA Space Radiation Summer School
Deadline: February 28

NCI Short-Term Scientist Exchange Program
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Comprehensive Minority Institution/Cancer Center Partnership (Limited Competition U54) (RFA-CA-09-501)

NCI Transition Career Development Award to Promote Diversity (K22) (PAR-09-069)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax


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