Case Comprehensive Cancer Center Newsletter

September 29, 2008

FUNDING OPPORTUNITY– Chemical Biology Consortium

The NCI, through its Operations and Technical Support Prime Contractor SAIC-Frederick, Inc., is seeking input and ideas from the scientific community and the biotechnology and pharmaceutical sector about an innovative initiative that will bridge the gap between basic scientific findings and NCI-supported clinical research and in the process establish the NCI as a leader in he area of innovative cancer therapeutics discovery.

The RFI addresses the feasibility of establishing an integrated network of chemical biologists, molecular oncologists, and screening centers from government, industry, and academia with specific drug development skills and expertise to address unmet needs in therapeutic oncology. NCI is calling this network the Chemical Biology Consortium (CBC). The response to this RFI will be used to assess the feasibility of assembling a consortium of experts to participate in the NCI's new Drug Discovery and Development Platform, whose mission is to advance first-in-class, targeted molecular therapeutic agents to the clinic. CBC-related activities will span the entire spectrum from target identification and validation through proof-of-concept (POC) Phase I/II clinical trials. Project Teams will be formed with Project Team Leaders tasked with coordinating the discovery and development of novel cancer therapeutics in an environment that fosters open cooperation and communication.

Deadline: October 27

For more information, please click here.

FUNDING OPPORTUNITY–Short-Term Scientist Exchange Program

The Short-Term Scientist Exchange program promotes collaborative research between established US and foreign scientists from developing countries by supporting, in part, exchange visits of cancer researchers to foreign laboratories. Visits of US scientists to overseas laboratories in developing countries may also be considered for support. The visits may be from one week to six months in duration.

Candidates must have a minimum of three years postdoctoral experience in cancer research and have an invitation from a qualified sponsor. Sponsors or exchangees from the US must be NCI-supported PIs, in either the intramural or extramural research programs. Foreign sponsors must be established scientists recognized in the international peer reviewed literature. Foreign candidates must be proficient in spoken and written English. Persons holding US permanent resident status or any work visa are not eligible for this program.

For details, please click here.

CALL FOR NOMINATIONS– AACR Future Leaders Symposium

The AACR Associate Member Council seeks institutional nominations of outstanding and innovative young investigators as speakers for the third annual Future Leaders Special Symposium to be held during the AACR 100th Annual Meeting, April 18-22, 2009 in Denver, CO. This is an unprecedented opportunity, during the world's largest meeting for cancer researchers, to showcase how your institution is contributing to the future of cancer research!

Nominees will be evaluated on scientific merit, research design, innovation, and independent contributions through a highly competitive selection process. The nominees who are selected as speakers will be treated as Invited Speakers to the Annual Meeting: they will receive complimentary registration and support for their travel; they will present a 15-20 minute platform presentation for this Symposium; and they will be introduced by a prominent senior researcher within their field. Your institution may submit up to two nominations.

Nominees must be graduate students, medical students or residents, clinical fellows, or postdoctoral fellows. Those with Junior faculty status are not eligible for nomination, including trainees expected to advance to junior faculty status prior to the Symposium. Each institution may submit two nominations, but the nominees must represent different areas of cancer research (e.g., laboratory, clinical, or translational research, epidemiology, etc.).

If you would like to nominate someone for this opportunity, please contact Gillian Irwin ( by Wednesday, October 15.

For details, please click here.


November 16
Fort Lauderdale, FL

The purpose of this annual symposium is to engage promising young clinical investigators in cooperative group clinical research. Individuals who meet the criteria are invited to submit an abstract for presentation at the fall ECOG meeting, which will take place November 14-16 in Fort Lauderdale, Florida. The symposium will tentatively take place between 8:30-11:00 am on November 16.

Abstracts should be emailed or faxed no later than October 10. For details, please click here.


Featured Article
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Most Cancer Clinical Trials Go Unpublished

Director's Update: Guest Update by Dr. Robert Croyle
Understanding the Media's Power to Influence Tobacco Use and Control


**All events are open to anyone interested in attending

September 29

Hematology/Oncology Research In Progress Seminar
Sarah Swerdlow
Graduate Student, Distelhorst Lab
Topic: Glucocorticoid Induction of Autophagy in Lymphocytes
12:00 pm WRB 2-136

Pathology Research Seminar Series
Harold Moses, MD
Professor, Molecular Oncology, Cancer Biology, Medicine, and Pathology
Vanderbilt University
Topic: TGF-beta Regulation of the Tumor Microenvironment
12:00 pm WRB 1-413

Physiology & Biophysics Seminar
Saurav Misra, PhD
Assistant Professor, Molecular Cardiology
CWRU/ Cleveland Clinic
Topic: All That and a Bag of CHIPS- Structural Studies on Cytosolic Protein Quality Control
4:00 pm SOM E501

September 30

Taussig Cancer Center Core Curriculum Series
David Adelstein, MD
Professor, Solid Tumor Oncology
Topic: Head and Neck Cancer
12:00 pm R3-002 Cleveland Clinic

October 1

Grand Rounds
Paolo Caimi, MD
Fellow, Div. of Hem/Onc
Topic: Hodgkin's Lymphoma
8:00 am Lerner B-151

October 2

Taussig Cancer Institute Core Curriculum Series
Andrew Stephenson, MD
Assistant Professor, Urology
CWRU/ Cleveland Clinic
Topic: Localized Prostate Cancer
12:00 pm R3-002 Cleveland Clinic

Neurosciences Seminar
Gordon Fishell, PhD
Professor, Cell Biology
New York University
Topic: Making Up Your Mind: The Developmental Genetic Origins of Cortical Interneurons
12:10 pm SOM E501

Practice-Based Research Network Seminar
Topic: Quantitative Data Analysis
6:00 pm Cuyahoga County Coroner's Office

October 3

Hematology/Oncology Fellows Seminar
Shanmuga Subbiah, MD
Fellow, Div. of Hem/Onc
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Neal Young, MD
Topic: Bone Marrow Failure and Telomere Biology
8:00 am R3/002-003 Cleveland Clinic

Skeletal Research Center Special Seminar
Steven Boyce, PhD
Professor, Surgery
University of Cincinnati
Topic: Engineered Human Skin for Wound Closure
9:00 am Millis 123


For a complete listing of LRI seminars click here.



**For more information on these symposiums, please contact Christine Rhoads.

Family-Centered Care
March 21, 2009
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow

MARK YOUR CALENDARS– 61st Annual Symposium on Cancer Research: Systems Biology of Cancer

October 30-November 1
University of Texas MD Anderson Cancer Center
Houston, TX

The University of Texas MD Anderson Cancer Center is pleased to host the 61st Annual Symposium on Cancer Research: Systems Biology of Cancer. This symposium will bring together internationally-recognized scientists from academia, industry, regulatory agencies, and patient advocates to describe and discuss state-of-the art information about how systems biology is transforming cancer research. This symposium is directed towards scientists, scientists-in-training, physicians, physicians-in-training, students, and fellows interested in integrating large molecular data sets to generate information relevant to understanding the mechanism of cancer growth and ultimately diagnosing and treating it.

For details, please click here.

MARK YOUR CALENDARS– AFAR Conference on Cancer and Aging

October 6-7
Union League Club
New York, NY

The American Federation on Aging Research (AFAR) is pleased to present Aging and Cancer: Two Sides of the Same Coin?, October 6-7 in New York. This two-day conference will explore fundamental aspects of aging and cancer processes and their interactions. Speakers will examine: genetic and epigenetic changes, environmental influences, and host factors such as oxidative stress and cell death. The evolutionary, cellular and molecular relationships among aging, tumor suppressor mechanisms and the development of cancer as well as the interactions of normal aging cells, stem cells and differences in the manifestation of cancer in young and old will also be discussed. Speakers will report on topics such as telomere biology; nuclear processes such as DNA damage, repair, replication, recombination and transcription; and relevant aspects of mitochondrial structure and function. The goal will be to elucidate genetic and epigenetic alterations that lead to aging and cancer phenotypes.

For more information, please click here.


ACS Ohio Division Pilot Grants
Deadline: September 29

Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)
Deadline: October 5

World Cancer Research Fund International
Deadline: October 13

Canary Foundation/ACS Postdoctoral Fellowship in the Early Detection of Cancer
Deadline: October 15

NCI Clinical Investigator Development Program
Deadline: October 15

ACS Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families
Deadline: October 15

AACR/American Cancer Society Award for Research Excellence in Cancer Epidemiology & Prevention
Nomination Deadline: October 15

AACR Award for Outstanding Achievement in Cancer Research Nomination Deadline: October 15

Multidisciplinary Clinical Research Training Program Clinical Research Scholars
Deadline: November 4

Susan G. Komen Promise Grants
Full Application Deadline: December 4

Sallie Rosen Kaplan Fellowship
Deadline: December 15

NIH Bulletin – Notices and Funding Opportunities

Exploratory Studies in Cancer Detection, Diagnosis, and Prognosis (R21) (PA-08-267)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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