Case Comprehensive Cancer Center Newsletter

August 25, 2008


Please join us in welcoming the following new members of the Case CCC:

Thomas LaFramboise, PhD
Assistant Professor, Genetics
Cancer Genetics Program

Jing Li, PhD
Assistant Professor, Electrical Engineering & Computer Science
Cancer Genetics Program

FUNDING OPPORTUNITY– Multidisciplinary Clinical Research Training Program Clinical Research Scholars

The Multidisciplinary Clinical Research Training Program seeks outstanding candidates to fill 5 Clinical Research (CR) Scholar positions available in July 2009. The training program is funded by NIH and it is a component of the Cleveland Clinical and Translational Science Collaborative. This innovative program is a collaboration involving CWRU, Cleveland Clinic, University Hospitals of Cleveland, MetroHealth Medical Center, and the Cleveland VA Medical Center. Each CR Scholar will embark on a 4-year program of intensive training in multidisciplinary team-based patient-oriented research, combining a novel educational program with mentored research experiences.

Applications will be accepted July 1 – November 4. For further details and application instructions, please click here.

STAND UP TO CANCER – Call for Ideas

AACR invites members of the cancer community to contribute to a groundbreaking effort to accelerate progress against cancer and directly impact patient care.

AACR is managing the blue ribbon scientific review of this innovative research program and will assure its integrity. The main objective is to identify and fund "SU2C Dream Team" translational research projects.

The number of Dream Teams to be formed will depend upon the total amount of funds raised through SU2C. Based on the scope of each Dream Team project, total support for each Team may reach up to $20 million for 3 years. The AACR is asking you to join this collaborative effort and contribute ideas to help shape the groundbreaking SU2C Dream Team translational research model. In issuing this call, AACR is not accepting research proposal for grant funding. Rather, they are inviting ideas for SU2C Dream Team translational research projects. For information, please click here.

On Friday, September 5 from 8:00 pm - 9:00 pm, ABC, CBS, and NBC will donate one hour of prime time for a simulcast, nationally televised fundraising event, uniting the nation as we "Stand Up To Cancer". As an official partner in this new and exciting initiative for cancer research, all funds raised through the event will be channeled through AACR.

Note from Dr. Gerson:

Dear Cancer Center members:

Please note this exciting initiative to think boldly about new collaborative research ideas that cut across institutions, disciplines, and diseases. I would like you to consider a concept for a proposal. While the new initiative is not asking for full proposals now, our effort to contribute ideas would position us to make a proposal based on the content we propose! Please consider an idea proposal, and send it to me for discussion with the senior leaders. If you want to also send it directly to the web site, please go ahead, but perhaps proposals would do better if vetted first!

Thanks for the great thoughts!

FUNDING OPPORTUNITY– Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)

The Cancer Imagine Program of NCI announces a new funding opportunity entitled "Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)". This cooperative agreement mechanism (PAR-08-225) is designed to promote research in quantitative imaging of tumor response to cancer therapies in clinical trial settings, with the overall goal of facilitating clinical decision making. To view the announcement, please click here.

The first date for receipt of applications under this announcement will be October 5, 2008. The Cancer Center would like to organize a response to this announcement. If you are interested, please contact as soon as possible.

MARK YOUR CALENDARS– Practice-Based Research Seminar Series

The Practice–Based Research Network is offering a free seminar series entitled "Practice-Based Network Research Seminar Series". The seminars are scheduled for Thursdays 6:00 pm - 7:00 pm this Fall, running from August 28- November 20 at the Cuyahoga County Coroner's Office. The series will cover the theory, history, scope, data collection, and analysis utilized in Practice-Based Research Networks. These networks make up a key component of the CTSC.

For more information about the series, the CTSC, or practice-based research in Cleveland, please click here. Free parking is available in the front of the building and refreshments will be served weekly. Attendees may earn CME and CREC credits. Please RSVP to if you are planning to attend.


November 16
Fort Lauderdale, FL

The purpose of this annual symposium is to engage promising young clinical investigators in cooperative group clinical research. Individuals who meet the criteria are invited to submit an abstract for presentation at the fall ECOG meeting, which will take place November 14-16 in Fort Lauderdale, Florida. The symposium will tentatively take place between 8:30-11:00 AM on November 16.

Abstracts should be emailed or faxed no later than October 10. For details, please click here.

MARK YOUR CALENDARS– AACR Centennial Symposium

October 27-28
Roswell Park Cancer Institute
Buffalo, NY

The AACR Centennial Symposium: The Future of Cancer Research: Science and Patient Impact will focus on the latest and future advances in cancer research, technologies, and techniques. This forward-looking centennial symposium will also be honoring the long history that the AACR has had with the Roswell Park Cancer Institute.

Advance Registration Deadline: September 15

For details, please click here.


Director's Update
The Dawn of Personalized Oncology

Cancer Research Highlights
Breast Cancer Relapse Risk Low after Chemotherapy or Tamoxifen

Novel Monoclonal Antibody Effective in Some Relapsed NHL Patients

Cord-Blood Transplant into Bone Restores Blood Counts

Esophageal Adenocarcinoma Rates Rise in Men and Women

Suicide Risk Higher in Cancer Patients than the General Population

Vitamin C Injections Slow Tumor Growth in Mice


**All events are open to anyone interested in attending

August 25

Hematology/Oncology Research in Progress Seminar
Danny Gray, PhD
Postdoc Fellow, von Recum Lab, Division of Biomedical Engineering
Topic: Embryonic Stem Cell Derived Endothelial Cells as Neovascularization Imaging
12:00 pm WRB 2-136

August 26

Taussig Cancer Institute Core Curriculum Series
Susan LeGrand, MD
Staff, Solid Tumor Oncology
Cleveland Clinic
Topic: An EBM Approach to Chemotherapy Induced Nausea and Vomiting
12:00 pm Cleveland Clinic R3-002

August 27

Grand Rounds
Balazs Halmos, MD
Assistant Professor, Medicine- Hem/Onc
Topic: Molecular Oncology
8:00 am Lerner B-151

Neurosciences Thesis Defense
Jessica Lerch-Haner
Department of Neurosciences
Topic: Serotonergic Transcriptional Programming Determines Maternal Behavior and Offspring Survival
12:00 pm SOM E609

August 28

Practice-Based Research Network Seminar
Topic: Theory, History, and Scope of PBRNs
6:00 pm Cuyahoga County Coroner's Building

August 29

Hematology/Oncology Fellows Seminar
Topic: TBA
8:00 am Wearn 137


For a complete listing of LRI seminars click here.



**For more information on these symposiums, please contact Christine Rhoads.

Family-Centered Care
March 21, 2009
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow


September 25-28
Hilton San Francisco

The Oncology Congress engages you in productive peer-to-peer discussions about cancer prevention, diagnosis, and treatment options, giving you the practical knowledge, tools, and insight needed to improve care and quality of life for your patients today.

The Case CCC has partnered with the Oncology Congress to offer a discounted registration rate for Case CCC members: $395 for physicians and $195 for nurses and physician assistants. To register, please click here, and use priority code COE8.

MARK YOUR CALENDARS– NanoMedicine Summit 2008

September 25-26
Ritz Carlton

The 2008 Cleveland NanoMedicine Summit, is the anchor event for Nano Week in Cleveland (in its fifth year) and will be co-hosted by NorTech's Nano-Network, the Cleveland Clinic Foundation and Case Western Reserve University. This conference has been incredibly successful in the past (as evidenced by national media attention and feedback from attendees) by bringing together scientists, clinicians, business professionals, investors and others to learn, discuss and interact under the umbrella of nanomedicine.

The 2008 Summit will focus on the use of nanoparticles for diagnostics and therapeutics. Session highlights include:
–Nanoparticles for Imaging Cancer and other Diseases
–Nanoparticles for Drug Delivery
–Nanoparticle Building Blocks
–Nanoparticles for Treatment of Disease
–Biological Investigation Using Nanoparticles

Many Cancer Center members are involved in this Summit. Drs. James Basilion, Vinod Labhasetwar, and Maciej Zborowski are on the Organizing Committee, and the following members are scheduled to speak: Drs. Stanton Gerson, Clemens Burda, Agata Exner, Vinod Labhasetwar, Horst von Recum, Pam Davis, Mark Cooper, and Thomas Budd.

For more information, please click here.

MARK YOUR CALENDARS– 61st Annual Symposium on Cancer Research: Systems Biology of Cancer

October 30-November 1
University of Texas MD Anderson Cancer Center
Houston, TX

The University of Texas MD Anderson Cancer Center is pleased to host the 61st Annual Symposium on Cancer Research: Systems Biology of Cancer. This symposium will bring together internationally-recognized scientists from academia, industry, regulatory agencies, and patient advocates to describe and discuss state-of-the art information about how systems biology is transforming cancer research. This symposium is directed towards scientists, scientists-in-training, physicians, physicians-in-training, students, and fellows interested in integrating large molecular data sets to generate information relevant to understanding the mechanism of cancer growth and ultimately diagnosing and treating it.

For details, please click here.

MARK YOUR CALENDARS– Biomedical Informatics Without Borders: Enabling Collaboration to Strengthen Research and Care

September 2-3
Bethesda, MD

The NCI cancer Biomedical Informatics Grid (caBIG) initiative and the NCRI Informatics Initiative are working jointly to harness the power of advances in biomedicine through collaboration. Please plan on attending Biomedical Informatics Without Borders: Enabling Collaboration to Strengthen Research and Care, to hear exciting presentations about how multinational collaborations are playing an important role in facilitating more connected and efficient research for diseases like cancer, and why such collaboration is critical to improving basic and critical research to speed the delivery of treatments and cures to patients.

Admission is free. For more information and to register, please click here. Online registration closed August 9, but onsite registration will be available.

MARK YOUR CALENDARS– AFAR Conference on Cancer and Aging

October 6-7
Union League Club
New York, NY

The American Federation on Aging Research (AFAR) is pleased to present Aging and Cancer: Two Sides of the Same Coin?, October 6-7 in New York. This two-day conference will explore fundamental aspects of aging and cancer processes and their interactions. Speakers will examine: genetic and epigenetic changes, environmental influences, and host factors such as oxidative stress and cell death. The evolutionary, cellular and molecular relationships among aging, tumor suppressor mechanisms and the development of cancer as well as the interactions of normal aging cells, stem cells and differences in the manifestation of cancer in young and old will also be discussed. Speakers will report on topics such as telomere biology; nuclear processes such as DNA damage, repair, replication, recombination and transcription; and relevant aspects of mitochondrial structure and function. The goal will be to elucidate genetic and epigenetic alterations that lead to aging and cancer phenotypes.

For more information, please click here.


AACR Landon Prizes
Nomination Deadline: August 25

AACR Henry Shepard Bladder Cancer Research Grants
Deadline: August 25

Doris Duke CSDA Bridge Grant
Deadline: September 1

NCI Cancer Prevention Fellowship Program
Deadline: September 1

National Lung Cancer Partnership/The LUNGevity Foundation
Deadline: September 2

International Myeloma Foundation Brian D. Novis Junior Research Grants and Senior Research Grants
Deadline: September 2

Mesothelioma Applied Research Foundation
Deadline: September 15

Pezcoller Foundation/ AACR International Award for Cancer Research
Deadline: September 15

Susan G. Komen Promise Grants
Pre-Application Deadline: September 25

ACS Ohio Division Pilot Grants
Application Deadline: September 29

World Cancer Research Fund International
Deadline: October 13

NCI Clinical Investigator Development Program
Application Deadline: October 15

ACS Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families
Application Deadline: October 15

Susan G. Komen Promise Grants
Full Application Deadline: December 4

Sallie Rosen Kaplan Fellowship
Deadline: December 15

NIH Bulletin – Notices and Funding Opportunities

Integration of Mouse Models into Human Cancer Research (U01) (RFA-CA-08-018)

Etiology, Prevention, and Treatment of Hepatocellular Carcinoma (R01) (PA-08-243)

Etiology, Prevention, and Treatment of Hepatocellular Carcinoma (R21) (PA-08-244)

Etiology, Prevention, and Treatment of Hepatocellular Carcinoma (P01) (PAR-08-245)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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