Case Comprehensive Cancer Center Newsletter

August 11, 2008


We would appreciate you taking a short survey about the Cancer Center retreat. We will use your feedback to plan next year's retreat. To take the survey, please click here. All members are encouraged to take the survey, whether or not you attended. We appreciate you taking the time to give us feedback, and are already looking forward to next year!

FUNDING OPPORTUNITY– Susan G. Komen Promise Grants

Susan G. Komen for the Cure has released Promise Grants for the 2008-2009 Research Program. Promise Grants provide up to $1.5M annually over five years to support programs with collaborative and cross-disciplinary research projects that provide integrated approaches to solving critical challenges to the rapid translation of scientific discoveries into new or enhanced clinical tools and applications that have the greatest potential to significantly reduce breast cancer incidence and/or mortality within the next decade. Integrated programs of research projects addressing critical challenges in population disparities in breast cancer outcomes and triple negative breast cancer are of special interest and may receive funding priority.

Pre-applications are required prior to starting a full application.
Pre-Application Deadline: September 25
Full Application Deadline: December 4

To view the RFA, please click here.

FUNDING OPPORTUNITY– Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)

The Cancer Imagine Program of NCI announces a new funding opportunity entitled "Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)". This cooperative agreement mechanism (PAR-08-225) is designed to promote research in quantitative imaging of tumor response to cancer therapies in clinical trial settings, with the overall goal of facilitating clinical decision making. To view the announcement, please click here.

The first date for receipt of applications under this announcement will be October 5, 2008. The Cancer Center would like to organize a response to this announcement. If you are interested, please contact as soon as possible.

FUNDING OPPORTUNITY–Pezcoller Foundation/ AACR International Award for Cancer Research

The prestigious Pezcoller Foundation–AACR International Award for Cancer Research was established in 1997 to annually recognize a scientist: who has made a major scientific discovery in basic cancer research OR who has made significant contributions to translational cancer research; who continues to be active in cancer research and has a record of recent, noteworthy publications; and whose ongoing work holds promise for continued substantive contributions to progress in the field of cancer. The Award is intended to honor an individual scientist. However, more than one scientist may be co-nominated and selected to share the Award when their investigations are closely related in subject matter and have resulted in work that is worthy of the Award.

Application Deadline: September 15

For more information, please click here.


The Cancer Prevention Fellowship Program (CPFP) at the National Cancer Institute (NCI) is accepting applications for 2009 Fellows from now through September 1, 2008. The Cancer Prevention Fellowship Program at the National Cancer Institute is an excellent postdoctoral training opportunity that provides training in public health and mentored research with world-renown investigators at the NCI. The overarching goal of the CPFP is to provide a strong foundation for clinicians and scientists to train in the field of cancer prevention and control. As part of the program, we offer training toward an MPH degree at an accredited university during the first year, followed by mentored research with investigators at the NCI. Opportunities for research cut across a wide range of methodologies: basic science laboratory studies, clinical studies, epidemiologic studies, community intervention trials, studies of the biological and social aspects of behavior, policy studies, and research on the ethics of prevention.

To learn more about this multidisciplinary program in cancer prevention, please click here.


November 16
Fort Lauderdale, FL

The purpose of this annual symposium is to engage promising young clinical investigators in cooperative group clinical research. Individuals who meet the criteria outlined below are invited to submit an abstract for presentation at the fall ECOG meeting, which will take place November 14-16 in Fort Lauderdale, Florida. The symposium will tentatively take place between 8:30-11:00 AM on November 16.

Abstracts should be emailed and faxed no later than October 10. For details, please click here.

MARK YOUR CALENDARS– AACR Centennial Symposium

October 27-28
Roswell Park Cancer Institute
Buffalo, NY

The AACR Centennial Symposium: The Future of Cancer Research: Science and Patient Impact will focus on the latest and future advances in cancer research, technologies, and techniques. This forward-looking centennial symposium will also be honoring the long history that the AACR has had with the Roswell Park Cancer Institute.

Advance Registration Deadline: September 15

For details, please click here.

MARK YOUR CALENDARS– 61st Annual Symposium on Cancer Research: Systems Biology of Cancer

October 30-November 1
University of Texas MD Anderson Cancer Center
Houston, TX

The University of Texas MD Anderson Cancer Center is pleased to host the 61st Annual Symposium on Cancer Research: Systems Biology of Cancer. This symposium will bring together internationally-recognized scientists from academia, industry, regulatory agencies, and patient advocates to describe and discuss state-of-the art information about how systems biology is transforming cancer research. This symposium is directed towards scientists, scientists-in-training, physicians, physicians-in-training, students, and fellows interested in integrating large molecular data sets to generate information relevant to understanding the mechanism of cancer growth and ultimately diagnosing and treating it.

For details, please click here.

MARK YOUR CALENDARS– Biomedical Informatics Without Borders: Enabling Collaboration to Strengthen Research and Care

September 2-3
Bethesda, MD

The NCI cancer Biomedical Informatics Grid (caBIG) initiative and the NCRI Informatics Initiative are working jointly to harness the power of advances in biomedicine through collaboration. Please plan on attending Biomedical Informatics Without Borders: Enabling Collaboration to Strengthen Research and Care, to hear exciting presentations about how multinational collaborations are playing an important role in facilitating more connected and efficient research for diseases like cancer, and why such collaboration is critical to improving basic and critical research to speed the delivery of treatments and cures to patients.

Admission is free. For more information and to register, please click here. Online registration closed August 9, but onsite registration will be available.


**All events are open to anyone interested in attending

August 11

Cancer Genetics/ Biology Journal Club cancelled; will resume late August

August 12

Taussig Cancer Center Core Curriculum Series
Eric Hsi, MD
Professor, Pathology
CWRU/ Cleveland Clinic
Topic: Peripheral Blood Smears
12:00 pm Cleveland Clinic R3-002

Pharmacology Faculty Recruitment Series
Jeongwu Lee, PhD
Staff Scientist, Neuro-Oncology
Topic: Tumor Stem Cells in Glioblastomas: New Model for Biology and Therapeutics
12:00 pm W331 (Pharm Seminar Rm)

August 13

Grand Rounds
Topic: TBA
8:00 am Lerner B-151

CSCRM Seminar
Rose Beck, MD, PhD
Assistant Professor, Pathology
Topic: Exploitation of Notch Signaling for Hematopoietic Cell Therapy
4:30 pm Cleveland Clinic NA5-08

August 14

Taussig Cancer Center Core Curriculum Series
James Cook, MD
Assistant Professor, Pathology
CWRU/ Cleveland Clinic
Topic: Ancillary Molecular Testing in Hematologic Malignancy
12:00 pm Cleveland Clinic R3-002

August 15

Hematology/Oncology Fellows Seminar
Topic: TBA
8:00 am Wearn 137


For a complete listing of LRI seminars click here.



**For more information on these symposiums, please contact Christine Rhoads.

Family-Centered Care
March 21, 2009
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow


September 25-28
Hilton San Francisco

The Oncology Congress engages you in productive peer-to-peer discussions about cancer prevention, diagnosis, and treatment options, giving you the practical knowledge, tools, and insight needed to improve care and quality of life for your patients today.

The Case CCC has partnered with the Oncology Congress to offer a discounted registration rate for Case CCC members: $395 for physicians and $195 for nurses and physician assistants. To register, please click here, and use priority code COE8.

MARK YOUR CALENDARS– NanoMedicine Summit 2008

September 25-26
Ritz Carlton

The 2008 Cleveland NanoMedicine Summit, is the anchor event for Nano Week in Cleveland (in its fifth year) and will be co-hosted by NorTech's Nano-Network, the Cleveland Clinic Foundation and Case Western Reserve University. This conference has been incredibly successful in the past (as evidenced by national media attention and feedback from attendees) by bringing together scientists, clinicians, business professionals, investors and others to learn, discuss and interact under the umbrella of nanomedicine.

The 2008 Summit will focus on the use of nanoparticles for diagnostics and therapeutics. Session highlights include:
–Nanoparticles for Imaging Cancer and other Diseases
–Nanoparticles for Drug Delivery
–Nanoparticle Building Blocks
–Nanoparticles for Treatment of Disease
–Biological Investigation Using Nanoparticles

Many Cancer Center members are involved in this Summit. Drs. James Basilion, Vinod Labhasetwar, and Maciej Zborowski are on the Organizing Committee, and the following members are scheduled to speak: Drs. Stanton Gerson, Clemens Burda, Agata Exner, Vinod Labhasetwar, Horst von Recum, Pam Davis, Mark Cooper, and Thomas Budd.

For more information, please click here.


Featured Article
Billionaires Boost Global Fight Against Tobacco

Cancer Research Highlights
Panel Recommends Against PSA Testing in Men 75 or Older

Lapatinib Limits Growth of Breast Cancer Brain Metastases in Mice

Eliminating a Common Bacterium Reduces Risk of Second Gastric Cancer

Metastatic Process Disrupted by Targeting Tumor Cells' Cytoskeleton

Agent Safe, Active in Hormone-Refractory Prostate Cancer

Gene Signatures May Help Predict Lung Cancer Survival

Guest Update by Ken Buetow
Personalized Medicine - BIG Health

MARK YOUR CALENDARS– Cancer Research UK Cambridge Research Institute Inaugural Annual Symposium

September 12-13
Cambridge, UK

Please mark your calendars for the Cancer Research UK Cambridge Research Institute's Inaugural Annual Symposium, Unanswered Questions in the Tumour Microenvironment, on September 12-13, 2008 at the Li Ka Shing Centre in Cambridge.

The Symposium format has been designed to provide an interactive forum for debate, and to especially encourage discussion of the critical questions and future challenges in tumour microenvironment research.

Registration Deadline: August 15

For details, please click here.

MARK YOUR CALENDARS– AFAR Conference on Cancer and Aging

October 6-7
Union League Club
New York, NY

The American Federation on Aging Research (AFAR) is pleased to present Aging and Cancer: Two Sides of the Same Coin?, October 6-7 in New York. This two-day conference will explore fundamental aspects of aging and cancer processes and their interactions. Speakers will examine: genetic and epigenetic changes, environmental influences, and host factors such as oxidative stress and cell death. The evolutionary, cellular and molecular relationships among aging, tumor suppressor mechanisms and the development of cancer as well as the interactions of normal aging cells, stem cells and differences in the manifestation of cancer in young and old will also be discussed. Speakers will report on topics such as telomere biology; nuclear processes such as DNA damage, repair, replication, recombination and transcription; and relevant aspects of mitochondrial structure and function. The goal will be to elucidate genetic and epigenetic alterations that lead to aging and cancer phenotypes.

For more information, please click here.


Letter of Intent Deadline: August 12

ASCO-NCI-European Organization for Research and Treatment of Cancer (EORTC) Diagnostic Tutorial
Deadline: August 15

AACR Stand Up to Cancer
Deadline: August 20

AACR Landon Prizes
Nomination Deadline: August 25

AACR Henry Shepard Bladder Cancer Research Grants
Deadline: August 25

Doris Duke CSDA Bridge Grant
Deadline: September 1

National Lung Cancer Partnership/The LUNGevity Foundation
Deadline: September 2

International Myeloma Foundation Brian D. Novis Junior Research Grants and Senior Research Grants
Deadline: September 2

Mesothelioma Applied Research Foundation
Deadline: September 15

World Cancer Research Fund International
Deadline: October 13

Sallie Rosen Kaplan Fellowship
Deadline: December 15

NIH Bulletin – Notices and Funding Opportunities

Small Business Innovation Research (SBIR) Program Contract Solicitation (PHS 2009-1) Now Available (NOT-OD-08-094)

NIH Offers SBIR Niche Assessment Program to Phase I Awardees (NOT-OD-08-100)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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