Case Comprehensive Cancer Center Newsletter

June 30, 2008

FUNDING OPPORTUNITY– Clinical and Translational Sciences Collaborative (CTSC)

The Cleveland Clinical and Translational Sciences Collaborative (CTSC) and the CWRU SOM, will provide seed money to faculty in multidisciplinary programs for Pilot Projects that will lead to efficient use of resources and support of inter-institutional, clinical translational research in the City of Cleveland. Investigators in the basic science and clinical departments in the SOM and the CTSC-affiliated institutions as well as in other departments in the University are eligible.

Applications may only be submitted by faculty members from member institutions and must include co-principal investigators from different schools or colleges or institutions. If the co-principal investigators are from the same school or college or institution, they must be from different departments and a strong case must be made in the application that the project is indeed interdisciplinary.

Application Deadline: July 15

For details and application instructions, please click here.

FUNDING OPPORTUNITY– AACR Henry Shepard Bladder Cancer Research Grants

The 2008 AACR Henry Shepard Bladder Cancer Research Grants represent a joint effort of the Henry H. Shepard Trust and the American Association for Cancer Research.

These two-year Grants will provide up to $250,000 in total support for innovative cancer research projects designed to accelerate the discovery, development, and application of new agents to treat bladder cancer and/or for pre-clinical research with direct therapeutic intent.

Laboratory-based projects must present plans with clinical collaborators indicating how the work will be translated into the clinic. Similarly, clinical studies must show how the work was derived from basic preclinical work and how results will be channeled back to laboratory-based collaborators.

Deadline: July 25

For details, please click here.


Congratulations to Cancer Center Member Ken Loparo, MD, who was recently awarded a CWRU Presidential Research Initiative Award for, "Complex Systems Analysis of Breathing Patterns in Lung Injury: Applications to Predict Outcomes and Limit Severity", a project completed with Frank Jacono, MD. To view the entire list of awardees, please click here.


Featured Article
Master Protein Controls Multiple Myeloma Cells

Cancer Research Highlights
Outreach Improves Breast Cancer Detection in African Americans

Osteopontin Helps Tumors Harness Bone Marrow Cells for Growth

LYN Kinase May Contribute to Imatinib Resistance in CML

Mortality Risks Highlight the Effect of Smoking

Director's Update: Guest Update by Dr. Julia H. Rowland
Cancer Survivorship Research Conference Maps New Challenges


**All events are open to anyone interested in attending

June 30

Cancer Genetics/ Biology Journal Club
Zhengqi Wang, PhD
Research Associate, Bunting Lab, Div. of Hem/Onc
Topic: The Role of STAT5 in Hematopoietic Stem Cell Transplantation
12:00 pm WRB 3-136 Conference Room (please note room change)

July 1

July 2

Grand Rounds cancelled

July 3

July 4

Happy Independence Day!


For a complete listing of LRI seminars click here.



**For more information on these symposiums, please contact Christine Rhoads.

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow

CASE CCC RETREAT– Last Chance to Register!

The 2008 scientific retreat of the Cancer Center will be July 11-12 at Sawmill Creek Resort and Conference Center in Huron, Ohio. This annual gathering is an important event for the Cancer Center, as it gives us the opportunity to evaluate our current initiatives and adjust our development and scientific priorities as needed. To view the agenda, please click here.

Please fill out the Registration Form and let us know whether or not you are able to attend. Please return the form to Gillian Irwin ( or fax 844-7832) as soon as possible.

ACS– Increased Funding for Cancer Control Career Development Awards for Primary Care Physicians

The American Cancer Society, the largest not-for-profit funding source for cancer research and training, is pleased to announce increased funding for the Cancer Control Career Development Awards for Primary Care Physicians (CCCDA). The purpose of this award is to encourage and assist in the development of primary care physicians who will pursue academic careers with an emphasis in cancer control.

Through the CCCDA, the Society seeks to provide opportunities for promising individuals to acquire skills in primary care practice, education, and research activities related to cancer control. Awards are for three years and for up to $100,000 per year. A maximum of $10,000 per year for the mentor(s) may be included in the budget.

The Society offers several other grant opportunities for primary care physicians in addition to the Cancer Control Career Development Awards for Primary Care Physicians. For a full description of all American Cancer Society grants, including applications, instructions, and policies, please click here.


The Case Comprehensive Cancer Center is currently accepting applications for it's American Cancer Society Institutional Research Grant. Pilot funding is available for projects in basic, clinical, behavioral, and epidemiological cancer research with awards up to $30,000 for 1 year cancer research projects that provide the basis for future independent grants.

Eligible applicants must:
–be within 6 years of their first full-time independent faculty appointment (or equivalent);
–be United States citizens, noncitizen nationals, or permanent residents of the United States;
–be eligible to apply as principal investigators for national grant support, but have no such support at the time of the IRG award;
–have Department Chair commitment for salary and space.

Deadline: August 11

To view application and instructions, please click here.

Faculty Positions Available – K12 Clinical Oncology Research Career Development Award

The Case Comprehensive Cancer Center is accepting applications for its K12 Clinical Oncology Research Career Development Award (CORP). Positions are available for July 2008 and July 2009. If you are interested in applying, please contact Margy Weinberg ( or 216-844-5375). Application deadline: August 1, 2008.

Program Directors
Stanton L. Gerson, MD, Director, Case Comprehensive Cancer Center, and
Alvin H. Schmaier, MD, Chief, Division of Hematology/Oncology

Career Development
Junior faculty appointment in medical, surgical, radiation, or pediatric departments at CWRU and UHCMC. Clinical oncology research that is focused on laboratory-based translational research and includes therapeutic clinical research.

MD with clinical training in an oncologic discipline. May be completing a residency and/or fellowship, depending on discipline. Interest and training in clinical trials and/or laboratory-based research. Intent to focus on translational research leading to a clinical trial. Willingness to participate in didactic training in clinical and translational research, to publish and author clinical trials. Minimum two-year commitment required.

Mentoring Faculty
Mentoring provided by nationally recognized basic, clinical, and translational faculty at CWRU and UHCMC.

The Case CCC has 9 multidisciplinary programs and 17 shared resources that promote focused cancer research and provide unique training opportunities.

Salaries and Research Seed Funds
Salary support at $75,000 for 75% effort plus generous annual research seed money provided through NCI-funded K12 CORP Award. Additional salary for 25% effort provided for clinical responsibilities.


FY2009 Third Frontier program funding announcements (RFPs) are expected to begin being issued in late July or early August. In our effort to improve internal coordination and identification of project proposals that support and complement the University R&D strengths and match Third Frontier goals and outcomes, to be more proactive in interactions with the Ohio Department of Development prior to the RFP releases, and with Eric Cottington's position not yet filled, we are testing a new approach to the University process this year.

Jim Pae in the Office of Research and Tech Management has agreed to serve as the point person for Third Frontier proposals until Eric's successor is on board. We are providing a summary of funding opportunities for FY2009 with brief descriptions of the purpose & outcomes of each program, total funding available for the programs, and expected timelines for each program RFP. Our experience has been that occasionally these time-lines can be delayed, but generally, the delay is no longer than 2 weeks. Consider the dates 95 percent firm.

Note that there will NOT be a call for Wright Centers of Innovation or Ohio Research Scholars in FY2009.

We are requesting that faculty who are interested in pursuing these funding opportunities provide general information about their proposal ideas to Jim Pae by July 2. They do not need to be elaborate and should include the following: Faculty member name and contact information; Name of Third Frontier program (for example, Biomedical Research and Commercialization Program); Title or concept for proposal; and Brief description of proposal (max. one paragraph ). Please submit all materials to Jim Pae by July 2.

MARK YOUR CALENDARS– AACR Centennial Conference

July 20-23
Hyatt Regency Monterey
Monterey, California

The AACR Centennial Conference on Translational Cancer Medicine 2008: Cancer Clinical Trials and Personalized Medicine is the second in the AACR Centennial Conference series on Translational Cancer Medicine and the first to be held in the United States. Translational research is a key programmatic priority of the AACR, and this meeting will showcase the latest scientific discoveries from the laboratory and their clinical applications.

For more information, please click here.

MARK YOUR CALENDARS– Cancer Immunology and Immunotherapy: Realizing the Promise

September 11-12
National Institutes of Health
Bethesda, MD

The Center for Cancer Research (CCR) at the National Cancer Institute will be hosting a two-day, national symposium entitled Cancer Immunology and Immunotherapy: Realizing the Promise. This meeting will host leaders in the field of cancer immunology and immunotherapy, include recent advances in both translational and clinical research, and should provide an exciting forum for discussion and debate on promising immunologic approaches to prevent and treat cancer.

Registration is free, but seating is limited so be sure to register early! Abstracts are being accepted for the poster session. Deadline for abstract submission is July 15.

For more information, please click here.


DOD PCRP Laboratory-Clinical Transition Award: Stage 1
LOI Deadline: June 30

DOD PRMRP Investigator-Initiated Research Award
Proposal Deadline: July 2

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Proposal Deadline: July 2

DOD PRMRP Translational Research Award
Proposal Deadline: July 2

DOD PRMRP Advanced Technology/Therapeutic Development Award
Proposal Deadline: July 2

DOD PRMRP Clinical Trial Award
Proposal Deadline: July 2

DOD OCRP Consortium Development Award
Proposal Deadline: July 9

Breast Cancer Research Foundation- AACR Grant for Translational Breast Cancer Research
Proposal Deadline: July 9

Komen-AACR Outstanding Investigator Award for Breast Cancer Research
Deadline: July 10

Cleveland Clinical and Translational Sciences Collaborative (CTSC)
Deadline: July 15

Susan G. Komen for the Cure: Career Catalyst in Disparities Research
Full Application Deadline: July 31

Susan G. Komen for the Cure: Post-Baccalaureate Training in Disparities Research
Full Application Deadline: July 31

ASCO-NCI-European Organization for Research and Treatment of Cancer (EORTC) Diagnostic Tutorial
Application Deadline: August 15

Doris Duke CSDA Bridge Grant
Deadline: September 1

National Lung Cancer Partnership/The LUNGevity Foundation
Deadline: September 2

Mesothelioma Applied Research Foundation
Deadline: September 15

NIH Bulletin – Notices and Funding Opportunities

Mechanisms of Immune Modulation (R01)(RFA-AT-08-003)

Mechanisms of Immune Modulation (R21) (RFA-AT-08-004)

Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies using Cells, Tissues, and Animal Models of Disease (R21) (PA-08-185)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue, Wearn
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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