Case Comprehensive Cancer Center Newsletter

June 2, 2008

NEW EQUIPMENT AND INFORMATIONAL SEMINAR– MesoScale Multiplex Analyzer

The Case Comprehensive Cancer Center and CTSC will be making available to the research community a multiplex analyzer with a broad range of analytical capabilities.

As an introduction we are holding a seminar on Wednesday, June 11 at 12:00 pm in WRB 3-136 to present more information about the technology. All are welcome to attend for pizza and a presentation by Jill Clampit, Senior Application Scientist at MesoScale Discovery, who will present Performance Advantages of Multiplex MSD Immunoassays.

MesoScale Discovery (MSD) single- and multi-plex immunoassays offer substantial assay performance advantages relative to conventional immunoassay techniques, such as ELISA or Western Blotting. Specifically, MSD immunoassays exhibit much larger linear dynamic range, greater precision, superior tolerance of complex sample matrices, and the ability to measure 1-10 analytes per well at low cost. Please attend to learn more about the MSD technology and relevant applications of MSD assay panels for Immunology, Oncology, and Metabolic research.

If you plan on attending this seminar or if you need directions to the Wolstein Building, please contact Paul Hartman, phh@case.edu or 216-844-1579. This event is sponsored by the Clinical Research Units of the Clinical and Translational Science Collaborative (UL1 RR024989) and the Case Comprehensive Cancer Center.


Faculty Positions Available Soon– K12 Clinical Oncology Research Career Development Award

The Case Comprehensive Cancer Center expects to have its K12 Clinical Oncology Research Career Development Award (CORP) funded soon, and wanted to circulate award information to any interested parties. Positions will be available for July 2008 and July 2009. If you are interested in applying, please contact Margy Weinberg (margy.weinberg@case.edu or 216-844-5375). An official announcement and deadline dates will be released when we receive a notice of award.

Program Directors
Stanton L. Gerson, MD, Director, Case Comprehensive Cancer Center, and
Alvin H. Schmaier, MD, Chief, Division of Hematology/Oncology

Career Development
Junior faculty appointment in medical, surgical, radiation, or pediatric departments at CWRU and UHCMC. Clinical oncology research that is focused on laboratory-based translational research and includes therapeutic clinical research.

Requirements
MD with clinical training in an oncologic discipline. May be completing a residency and/or fellowship, depending on discipline. Interest and training in clinical trials and/or laboratory-based research. Intent to focus on translational research leading to a clinical trial. Willingness to participate in didactic training in clinical and translational research, to publish and author clinical trials. Minimum two-year commitment required.

Mentoring Faculty
Mentoring provided by nationally recognized basic, clinical, and translational faculty at CWRU and UHCMC.

Resources
The Case CCC has 9 multidisciplinary programs and 17 shared resources that promote focused cancer research and provide unique training opportunities.

Salaries and Research Seed Funds
Salary support at $75,000 for 75% effort plus generous annual research seed money provided through NCI-funded K12 CORP Award. Additional salary for 25% effort provided for clinical responsibilities.


CASE CCC 2008 RETREAT

The annual scientific retreat of the Cancer Center will be July 11-12 at The Lodge at Sawmill Creek, a lovely setting in Huron, Ohio that offers numerous outdoor activities including golf, swimming, volleyball, tennis, basketball, and walking trails. There is also an indoor pool, fitness center and game room on the grounds. Nearby attractions include Cedar Point, Sheldon Marsh Nature Preserve, wineries, the Lake Erie Islands, and Maritime Museums.

The overall theme will be building disease-related translational initiatives. The program will begin on Friday with presentations and discussions of the Basic Science of Cancer Focus Groups. Afternoon topics will include presentations and discussions on informatics development and capabilities throughout the School and presentations from the Cancer Control and Prevention and Aging Research Programs. Later in the afternoon we will have our individual program discussions.

After cocktails and dinner Friday evening, Dr. George Stark will discussion drug discovery.

Saturday's program will be directed toward the disease-based initiatives and will include presentations and discussions aimed to link the clinical translational elements. Along with updates to specific disease based initiatives, there will be presentations and discussions that highlight the Tissue Biorepository Resource and clinical trials support.

The program will end at noon on Saturday, though we encourage you to stay and enjoy area attractions.

A detailed agenda will be released closer to the event. Please direct any questions to gillian.irwin@case.edu.

EVENTS

**All events are open to anyone interested in attending

June 2

Cancer Genetics/ Biology Journal Club
Jonathan Kenyon
Graduate Student, Gerson Lab, Div. of Hem/Onc
CWRU/ UH
Topic: Aging Hematopoietic Stem Cells and the DNA Mismatch Repair Pathway
12:00 pm WRB 2-136 Conference Room


June 3

Systems Biology Focus Group
Tomas Radivoyevitch, PhD
Assistant Professor, Epidemiology & Biostatistics
CWRU
Topic: Equilibrium Model Selection
10:00 am WRB 3-136
Abstract

Stem Cell Biology
Shideng Bao, PhD
Associate Professor, Radiation Oncology & Neurosurgery
University of Colorado School of Medicine
Topic: Glioma Stem Cells: Therapeutic Resistance and Molecular Targeting
10:00 am NE1-205 Cleveland Clinic


June 4

Grand Rounds
Gregory Chipman, MD
Fellow, Division of Hem/Onc
CWRU/ UH
Topic: Renal Cell Carcinoma
8:00 am Lerner B-151

Department of Pharmacology and Cancer Center Faculty Candidate
You-Wei Zhang, PhD
2:00 pm Wood Building W331

CSCRM Seminar
Brandi Ormerod, PhD
Assistant Professor, Biomedical Engineering
University of Florida
Topic: NSAIDs Rescue Neuroinflammation-Impaired Hippocampal Neurogenesis and Memory: Implications for Stem Cell Strategies
4:30 pm NA5-08 Cleveland Clinic


June 5

Aging-Cancer Research Seminar cancelled

Neurosciences Seminar
Arnold R. Kriegstein, MD, PhD
Director, Institute for Regeneration Medicine
University of California, San Francisco School of Medicine
Topic: Generation and Migration of Cortical Neurons
12:10 pm BRB 105


June 6

Cancer Center Seminar Series/ Blood Club will resume in the Fall

Hematology/Oncology Fellows Seminar cancelled

Taussig Cancer Center Grand Rounds
Saul Rosenberg, MD
Emeritus (Active) Professor, Medicine- Oncology
Stanford University Medical Center
Topic The Cure of Hodgkin's Disease: How We Got There
8:00 am R3/002-003 Cleveland Clinic

more

For a complete listing of LRI seminars click here.


MARK YOUR CALENDARS:

UPCOMING CANCER CENTER SYMPOSIUMS

**For more information on these symposiums, please contact Christine Rhoads.

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood
Course Directors: Janice Lyons, MD, Halle Moore, MD, and Paula Silverman, MD
Brochure and Registration

ASCO Review 2008
June 27
InterContinental Hotel & Bank of America Conference Center
Course Directors: Robert Dreicer, MD and Hillard Lazarus, MD
Brochure and Registration

Head and Neck Conference
April 17, 2009 (Please note date change)
Holiday Inn, Independence
Details to follow


NCI Cancer Bulletin

Featured Article
Studies Make Case for Finasteride to Prevent Prostate Cancer

Cancer Research Highlights
Potent Social Forces Influence Smoking Behavior

MRI May Contribute to Rising Mastectomy Rates

BRCA2 Linked to Prostate Cancer Incidence and Aggression

Vitamin D Not Associated with Decreased Prostate Cancer Risk

Director's Update: Guest Update by Dr. Daniela S. Gerhard
TCGA Moving Molecular Oncology Forward

Spotlight
A New Cancer Specialty: Follow-up for Long-term Survivors


MARK YOUR CALENDARS– Let's Band Together

The Ireland Cancer Center and Rainbow Babies & Children's Hospital present Let's Band Together: Inaugural Adolescent & Young Adult (AYA) Cancer Initiative Symposium, Friday, June 13 from 10:00 am - 2:00 pm at Marriott Cleveland Key Center. Patients, healthcare professionals, clinicians, government leaders and others interested in learning more about ongoing efforts to fight against adolescent and young adult cancer are encouraged to attend. For details and registration information, please click here, or contact Sante Ghetti at (216)844-4886 for more information.

Also mark your calendars for the Rise Above It (RAI) Inaugural "Black Dress, Yellow Tie" Keep the Fight Alive! Reception that evening, from 6:00 pm - 11:30 pm also at the Marriott Cleveland Key Center. For details on this event, click here. To learn more about RAI, please click here.


MARK YOUR CALENDARS–AACR Accelerating Anticancer Agent Development and Validation Workshop

June 18-20, 2008
North Bethesda, MD

This is a postgraduate workshop for clinical and translational investigations focused on strategic planning to develop and validate new anticancer and cancer prevention agents and pathways. This is an intensive and interactive workshop in how to design effective strategies– from clinical trial initiative, to enabling trials, to pivotal efficacy trials– to develop new anticancer and prevention agents, taught by a distinguished faculty from across the academic, industry, consumer, and government (FDA) sectors.

For more information, click here.


MARK YOUR CALENDARS– Cancer Health Disparities Summit

July 14-16
Bethesda North Marriott Hotel and Conference Center
Bethesda, MD

The National Cancer Institute (NCI) Center to Reduce Cancer Health Disparities (CRCHD) is pleased to present the Cancer Health Disparities Summit 2008, July 14–16, at the Bethesda North Marriott Hotel and Conference Center, Bethesda, Maryland. The overall theme for this year's Summit is Eliminating Cancer Health Disparities Through Science, Training, and Community. The Cancer Health Disparities 2008 will highlight the science of the programs and grantees funded through the CRCHD.

For more information, please click here.


MARK YOUR CALENDARS– AACR Centennial Conference

July 20-23
Hyatt Regency Monterey
Monterey, California

The AACR Centennial Conference on Translational Cancer Medicine 2008: Cancer Clinical Trials and Personalized Medicine is the second in the AACR Centennial Conference series on Translational Cancer Medicine and the first to be held in the United States. Translational research is a key programmatic priority of the AACR, and this meeting will showcase the latest scientific discoveries from the laboratory and their clinical applications.

For more information, please click here.


MARK YOUR CALENDARS– Cancer Immunology and Immunotherapy: Realizing the Promise

September 11-12
National Institutes of Health
Bethesda, MD

The Center for Cancer Research (CCR) at the National Cancer Institute will be hosting a two-day, national symposium entitled Cancer Immunology and Immunotherapy: Realizing the Promise. This meeting will host leaders in the field of cancer immunology and immunotherapy, include recent advances in both translational and clinical research, and should provide an exciting forum for discussion and debate on promising immunologic approaches to prevent and treat cancer.

Registration is free, but seating is limited so be sure to register early! Abstracts are being accepted for the poster session. Deadline for abstract submission is July 15.

For more information, please click here.



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 2

DOD PRMRP Investigator-Initiated Research Award
Pre-App Deadline: June 4

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Pre-App Deadline: June 4

DOD PRMRP Translational Research Award
Pre-App Deadline: June 4

DOD PRMRP Advanced Technology/Therapeutic Development Award
Pre-App Deadline: June 4

DOD PRMRP Clinical Trial Award
Pre-App Deadline: June 4

Administrative Supplements to Active R01, P01, P50, U01, and U19 Grants Focused on Cancer Survivorship
Deadline: June 9

Susan G. Komen for the Cure: Career Catalyst in Disparities Research
Pre-Application Deadline: June 10

DOD PCRP Clinical Consortium Agreement
Pre-App/LOI Deadline: June 11

DOD PCRP Clinical Trial Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Research Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Training Award
Pre-App/LOI Deadline: June 11

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
Pre-App/LOI Deadline: June 11

HRSA Patient Navigator Outreach and Chronic Disease Prevention Demonstration Program
Application Deadline: June 13

Susan G. Komen for the Cure: Post-Baccalaureate Training in Disparities Research
Pre-Application Deadline: June 19

DOD OCRP Consortium Development Award
Pre-Application Deadline: June 25

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
LOI Deadline: June 30

DOD PRMRP Investigator-Initiated Research Award
Proposal Deadline: July 2

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Proposal Deadline: July 2

DOD PRMRP Translational Research Award
Proposal Deadline: July 2

DOD PRMRP Advanced Technology/Therapeutic Development Award
Proposal Deadline: July 2

DOD PRMRP Clinical Trial Award
Proposal Deadline: July 2

DOD OCRP Consortium Development Award
Proposal Deadline: July 9

Cleveland Clinical and Translational Sciences Collaborative (CTSC)
Deadline: July 15

Susan G. Komen for the Cure: Career Catalyst in Disparities Research
Full Application Deadline: July 31

Susan G. Komen for the Cure: Post-Baccalaureate Training in Disparities Research
Full Application Deadline: July 31

Doris Duke CSDA Bridge Grant
Deadline: September 1


NIH Bulletin – Notices and Funding Opportunities

Correction of Application Receipt Dates for "Paul Calabresi Career Development Award for Clinical Oncology (K12)&(NOT-CA-08-022)

Correction of the Response Due date of Request for Information (RFI): To Solicit Ideas for Common Fund / Roadmap Trans-NIH Strategic Initiatives NOT-RM-08-014 (NOT-RM-08-020)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.green@uhhospitals.org
 
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