Case Comprehensive Cancer Center Newsletter

May 19, 2008

CASE CCC 2008 RETREAT

The annual scientific retreat of the Cancer Center will be July 11-12 at The Lodge at Sawmill Creek, a lovely setting in Huron, Ohio that offers numerous outdoor activities including golf, swimming, volleyball, tennis, basketball, and walking trails. There is also an indoor pool, fitness center and game room on the grounds. Nearby attractions include Cedar Point, Sheldon Marsh Nature Preserve, wineries, the Lake Erie Islands, and Maritime Museums.

The overall theme will be building disease-related translational initiatives. The program will begin on Friday with presentations and discussions of the Basic Science of Cancer Focus Groups. Afternoon topics will include presentations and discussions on informatics development and capabilities throughout the School and presentations from the Cancer Control and Prevention and Aging Research Programs. Later in the afternoon we will have our individual program discussions.

After cocktails and dinner Friday evening, Dr. George Stark will discussion drug discovery.

Saturday's program will be directed toward the disease-based initiatives and will include presentations and discussions aimed to link the clinical translational elements. Along with updates to specific disease based initiatives, there will be presentations and discussions that highlight the Tissue Biorepository Resource and clinical trials support.

The program will end at noon on Saturday, though we encourage you to stay and enjoy area attractions.

A detailed agenda will be released closer to the event. Please direct any questions to gillian.irwin@case.edu.


NEW MEMBERS CORNER

Please join us in welcoming the following new members of the Case CCC:

Paul Barr, MD
Assistant Professor, Medicine- Hem/Onc
Clinical Member

Wei Xin, MD, PhD
Assistant Professor, Pathology
Molecular Mechanisms of Oncogenesis Program (Basic Science of Cancer)

Lan Zhou, MD, PhD
Assistant Professor, Pathology
Stem Cells and Hematologic Malignancies Program


KUDOS...

Congratulations to Cancer Center Members Pingfu Fu and Tom Radivoyevitch, who were chosen to attend the American Association for Cancer Research (AACR) Cancer Biostatistics Workshop, July 13-19, 2008 in Sonoma, California. Drs. Fu and Radivoyevitch were among 28 junior and 14 mid-level academic biostatisticians who were awarded full (entry level and junior faculty) or partial (mid-level faculty) support to attend this workshop.

For more information on the Information on the AACR Biostatistics Workshop, please click here.


ASCO Annual Meeting

May 30 - June 3
McCormick Place
Chicago, IL

The American Society of Clinical Oncology (ASCO) Annual Meeting is scheduled for May 30- June 3 in Chicago. This meeting is the premier scientific and educational event in oncology, drawing 30,000 attendees worldwide. As a forum for collaboration and communication, the ASCO Annual Meeting brings together oncologists of all disciplines, researchers, nurses, and patient advocates in the fight against cancer. The 2008 Meeting will unite the global oncology community with the common goals of delivering the highest quality patient care and innovating treatment advances.

Please plan on attending the presentations of fellow Cancer Center Members: Dr. Joanna Brell is scheduled to present The Toxicity of Targeted Therapies: Specific Effects of New Agents from 1:00 pm - 2:15 pm on May 30; Dr. Derek Raghavan is scheduled to present Cancer Care in Minority Populations from 9:45 am - 11:00 am on June 2.

For details, please click here.


NCI CANCER BULLETIN

Featured Article
Genome Scans Find Clues to Childhood Cancer

Cancer Research Highlights
Mammography Plus Breast Ultrasound Yields Mixed Results

Sugar and Signals: EGFR's Dual Role in Cancer

Two Proteins Interact to Turn Moles Cancerous

Nutlin-3a Induces Senescence through p53

Long-Term Smoking Cessation Cuts Cancer, Mortality Risk

Breast Cancer Stem Cells May Resist Chemotherapy

Director's Update
The Future of Cancer Research: What's at Stake


FUNDING OPPORTUNITY– Case CCC Request for Pilot Project Applications

The Case CCC is currently accepting applications for a "Multi-Investigator Grant Initiative to Promote the Basic Science Scientific Focus Group Areas of the Cancer Center". Awards of up to $50,000 for 1 year are available.

Principal Investigators must be full-time members of the faculty at Case Western Reserve University or Cleveland Clinic Lerner College of Medicine and members of the Case Comprehensive Cancer Center.

Application Deadline: May 27

To view the RFA, please click here. RFA, Instructions and Cover Sheet are also available on the Cancer Center homepage.

EVENTS

**All events are open to anyone interested in attending

May 19

Cancer Genetics/Biology Journal Club cancelled due to Hem/Onc Special Conference

Cultural and Linguistic Competency: Implications for Research
Guest Speaker and Facilitator: Tawara Goode, MA
Assistant Professor & Director, National Center for Cultural Competence
Department of Pediatrics
Georgetown University Medical Center
8:00am - 1:00 pm WRB 1413

Hematology/Oncology Special Conference
Vardan T. Karamyan, PhD
Associate Research Scientist, Pharmacology
University of Mississippi
Topic: A Novel Component of the Brain Angiotensin System: Discovery and Characterization of the Non-AT1, Non-AT2 Angiotensin Binding Site
12:00 pm WRB 2-136

Pathology Seminar
Man-Sun Sy, PhD
Professor, Pathology
CWRU
Topic: The Saga of Prion: From Mad Cow Disease to Cancer
12:00 pm WRB 1413


May 20


May 21

Developmental Therapeutics Program meeting cancelled

Grand Rounds
Tamila Kindwall-Keller, DO
Assistant Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Relapsed/Refractory CLL and Stem Cell Transplant
8:00 am Lerner B-151


May 22

Taussig Cancer Center Core Curriculum Series
Jenny Kim, MD
Taussig Cancer Center
Cleveland Clinic
Topic: TBA
12:00 pm R3-002 Cleveland Clinic

Neurosciences Seminar
Thomas H. Large, PhD
Sepracor, Inc.
Topic: Drug Hunting in the 21st Century
12:10 pm BRB 105

Aging-Cancer Research Seminar
Julia Hannum Rose, PhD, MA
Professor, Medicine- Geriatrics and Palliative Care
CWRU/ MetroHealth
Topic: Middle-Aged and Older Patient Engagement in a Coping and Communication Support Intervention During the Early Treatment Phase of Late Stage Cancer
4:00 pm BRB 732


May 23

Hematology/Oncology Fellows
Yael Hegerfeldt, MD
Fellow, Division of Hem/Onc
CWRU/ UH
Topic: TBA
8:00 am Wearn 137

Cancer Center Seminar Series/ Blood Club
Henry J. Thompson, PhD
Professor, Cancer Prevention Laboratory
Colorado State University
Topic: Dietary Energy Intake, Exercise and Energy Sensing in the Regulation of Carcinogenesis
12:00 pm BRB 105

more

For a complete listing of LRI seminars click here.


MARK YOUR CALENDARS:

UPCOMING CANCER CENTER SYMPOSIUMS

**For more information on these symposiums, please contact Christine Rhoads.

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood
Course Directors: Janice Lyons, MD, Halle Moore, MD, and Paula Silverman, MD
Brochure and Registration

ASCO Review 2008
June 27
InterContinental Hotel & Bank of America Conference Center
Course Directors: Robert Dreicer, MD and Hillard Lazarus, MD
Brochure and Registration

Head and Neck Conference
October 31
Holiday Inn, Independence
Details to follow


RACE FOR THE PLACE- Join Our Team!

The Case Comprehensive Cancer Center has created a team for the Race for the Place, a fundraiser that benefits The Gathering Place in Beachwood, Ohio.

For those of you that are not familiar with the Gathering Place, it is a support center providing programs and services free of charge for individuals and families touched by cancer.

Each year, the first Sunday in June (June 1, 2008) is National Cancer Survivors' Day. On this day, The Gathering Place hosts a 5K / 1 Mile event called Race for the Place. This event helps to raise the money that allows The Gathering Place to offer all of their services free of charge.

If you want to join the Case CCC team, please click here or email gillian.irwin@case.edu. Family and friends are also welcome to join our team! It really is a great experience for everyone who is involved.

If cannot run the race, but would still like to help, please consider making a small donation to sponsor our team. Every little bit helps. To sponsor us, please click here.


MARK YOUR CALENDARS– Ohio Collaborative Conference on Bioinformatics

June 2-4, 2008
University of Toledo
Toledo, Ohio

The Third Annual Ohio Collaborative Conference on Bioinformatics will be held at the University of Toledo June 2-4. This conference will provide an interdisciplinary forum for discussing approaches, research findings, and experiences regarding computational investigations of biological problems. An important goal of the conference continues to be the fostering of long-term collaborative relationships among informatics and life sciences researchers from academia, government and industry, spanning Ohio and adjacent states. This meeting is not only for experts in bioinformatics, but also for those who make substantial use of bioinformatic tools in their research/development work, or would like to expand such use.

For more information, please click here.


MARK YOUR CALENDARS– Let's Band Together

The Ireland Cancer Center and Rainbow Babies & Children's Hospital present Let's Band Together: Inaugural Adolescent & Young Adult (AYA) Cancer Initiative Symposium, Friday, June 13 from 10:00 am - 2:00 pm at Marriott Cleveland Key Center. Patients, healthcare professionals, clinicians, government leaders and others interested in learning more about ongoing efforts to fight against adolescent and young adult cancer are encouraged to attend. For details and registration information, please click here, or contact Sante Ghetti at (216)844-4886 for more information.

Also mark your calendars for the Rise Above It (RAI) Inaugural "Black Dress, Yellow Tie" Keep the Fight Alive! Reception that evening, from 6:00 pm - 11:30 pm also at the Marriott Cleveland Key Center. For details on this event, click here. To learn more about RAI, please click here.


MARK YOUR CALENDARS–AACR Accelerating Anticancer Agent Development and Validation Workshop

June 18-20, 2008
North Bethesda, MD

This is a postgraduate workshop for clinical and translational investigations focused on strategic planning to develop and validate new anticancer and cancer prevention agents and pathways. This is an intensive and interactive workshop in how to design effective strategies– from clinical trial initiative, to enabling trials, to pivotal efficacy trials– to develop new anticancer and prevention agents, taught by a distinguished faculty from across the academic, industry, consumer, and government (FDA) sectors.

For more information, click here.


MARK YOUR CALENDARS– Cancer Health Disparities Summit

July 14-16
Bethesda North Marriott Hotel and Conference Center
Bethesda, MD

The National Cancer Institute (NCI) Center to Reduce Cancer Health Disparities (CRCHD) is pleased to present the Cancer Health Disparities Summit 2008, July 14–16, at the Bethesda North Marriott Hotel and Conference Center, Bethesda, Maryland. The overall theme for this year's Summit is Eliminating Cancer Health Disparities Through Science, Training, and Community. The Cancer Health Disparities 2008 will highlight the science of the programs and grantees funded through the CRCHD.

For more information, please click here.


MARK YOUR CALENDARS– AACR Centennial Conference

July 20-23
Hyatt Regency Monterey
Monterey, California

The AACR Centennial Conference on Translational Cancer Medicine 2008: Cancer Clinical Trials and Personalized Medicine is the second in the AACR Centennial Conference series on Translational Cancer Medicine and the first to be held in the United States. Translational research is a key programmatic priority of the AACR, and this meeting will showcase the latest scientific discoveries from the laboratory and their clinical applications.

For more information, please click here.


MARK YOUR CALENDARS– Cancer Immunology and Immunotherapy: Realizing the Promise

September 11-12
National Institutes of Health
Bethesda, MD

The Center for Cancer Research (CCR) at the National Cancer Institute will be hosting a two-day, national symposium entitled Cancer Immunology and Immunotherapy: Realizing the Promise. This meeting will host leaders in the field of cancer immunology and immunotherapy, include recent advances in both translational and clinical research, and should provide an exciting forum for discussion and debate on promising immunologic approaches to prevent and treat cancer.

Registration is free, but seating is limited so be sure to register early! Abstracts are being accepted for the poster session. Deadline for abstract submission is July 15.

For more information, please click here.



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

HRSA Patient Navigator Outreach and Chronic Disease Prevention Demonstration Program
LOI Deadline: May 22

DOD PCRP Idea Development Award
Pre-App/LOI Deadline: May 22

DOD PCRP New Investigator Award
Pre-App/LOI Deadline: May 22

DOD PCRP Prostate Cancer Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Physician Research Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Collaborative Undergraduate HBCU Student Summer Training Program Award Award
Pre-App/LOI Deadline: May 22

DOD PCRP Synergistic Idea Development Award
Pre-App/LOI Deadline: May 22

Administrative Supplements for Making Knockout Mice
Deadline: June 1

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 2

DOD PRMRP Investigator-Initiated Research Award
Pre-App Deadline: June 4

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Pre-App Deadline: June 4

DOD PRMRP Translational Research Award
Pre-App Deadline: June 4

DOD PRMRP Advanced Technology/Therapeutic Development Award
Pre-App Deadline: June 4

DOD PRMRP Clinical Trial Award
Pre-App Deadline: June 4

Administrative Supplements to Active R01, P01, P50, U01, and U19 Grants Focused on Cancer Survivorship
Deadline: June 9

Susan G. Komen for the Cure: Career Catalyst in Disparities Research
Pre-Application Deadline: June 10

DOD PCRP Clinical Consortium Agreement
Pre-App/LOI Deadline: June 11

DOD PCRP Clinical Trial Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Research Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Training Award
Pre-App/LOI Deadline: June 11

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
Pre-App/LOI Deadline: June 11

HRSA Patient Navigator Outreach and Chronic Disease Prevention Demonstration Program
Application Deadline: June 13

Susan G. Komen for the Cure: Post-Baccalaureate Training in Disparities Research
Pre-Application Deadline: June 19

DOD OCRP Consortium Development Award
Pre-Application Deadline: June 25

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
LOI Deadline: June 30

DOD PRMRP Investigator-Initiated Research Award
Proposal Deadline: July 2

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Proposal Deadline: July 2

DOD PRMRP Translational Research Award
Proposal Deadline: July 2

DOD PRMRP Advanced Technology/Therapeutic Development Award
Proposal Deadline: July 2

DOD PRMRP Clinical Trial Award
Proposal Deadline: July 2

DOD OCRP Consortium Development Award
Proposal Deadline: July 9

Susan G. Komen for the Cure: Career Catalyst in Disparities Research
Full Application Deadline: July 31

Susan G. Komen for the Cure: Post-Baccalaureate Training in Disparities Research
Full Application Deadline: July 31

Doris Duke CSDA Bridge Grant
Deadline: September 1


NIH Bulletin – Notices and Funding Opportunities

Extension of Several NRSA Training (T), NRSA Fellowship (F), and Career Development (K) Funding Opportunity Announcements (NOT-OD-08-069)

Findings of Scientific Misconduct (NOT-OD-08-070)

NIH Implements New Procedures to Protect NIH Application Data Sent to Peer Reviewers on Compact Disks (NOT-OD-08-071)

Change in Scientific Contact for PA-07-176 and PA-06-405, Studies of Energy Balance and Cancer in Humans (R01 and R21, respectively)(NOT-CA-08-020)

Notice of Intent to Publish a Request for Applications: Renewal of the National Technology Centers for Networks and Pathways Program (NOT-RM-08-016)

Change in Application Receipt Date to RFA-RM-08-001 (NOT-RM-08-018)

SBIR Phase II Bridge Awards to Accelerate the Development of New Cancer Therapies and Cancer Imaging Technologies Toward Commercialization (SBIR [R44]) (RFA-CA-08-021)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.green@uhhospitals.org
 
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