Case Comprehensive Cancer Center Newsletter

April 7, 2008

FUNDING OPPORTUNITY– Case CCC Request for Pilot Project Applications

The Case CCC is currently accepting applications for a "Multi-Investigator Grant Initiative to Promote the Basic Science Scientific Focus Group Areas of the Cancer Center". Awards of up to $50,000 for 1 year are available.

Principal Investigators must be full-time members of the faculty at Case Western Reserve University or Cleveland Clinic Lerner College of Medicine and members of the Case Comprehensive Cancer Center.

Application Deadline: May 27

To view the RFA, please click here. RFA, Instructions and Cover Sheet are also available on the Cancer Center homepage.


FUNDING OPPORTUNITY– NIH/Fogarty International Clinical Research Fellowships

The NIH/Fogarty International Clinical Research Scholars (FICRS) Support Center at Vanderbilt University/ Association of American Medical Colleges (AAMC) is pleased to announce a new one year clinical research training program for US citizens or permanent residents in either post-residency clinical fellowships or in other health-related post-doctoral programs.

The ICRF Program supports one year of mentored clinical research in a developing country setting. Definitions of developing counties are those designated by the World Bank as low income, lower middle, or upper middle income. Applicants for the fellowship must develop a collaborative research proposal with an eligible institution overseas.

The proposed research must be clinical research related to:

  • oncology, including radiation therapy, physiology, and other cancer-related issues;
  • diseases of the heart, blood vessels, lung, and blood; blood resources; and sleep disorders;
  • ophthalmology and eye-health related issues; or
  • STDs, HIV/AIDS-related research.

The Fellowship is an opportunity designed to immerse medical professionals and health scientists in training in issues of global health and international collaboration. Applicants must be citizens or permanent residents of the US.

Application Deadline: April 30

For more information, please click here.


FUNDING OPPORTUNITY– Prostate Cancer Foundation Young Investigator Awards

The Prostate Cancer Foundation is currently accepting applications for their new Young Investigator Awards. Highly innovative basic science programs will be carefully considered, but priority will be given to "bench to bedside" translational research proposals with the potential to deliver near term benefit to patients.

Applicants need not be trained specifically in clinical prostate cancer research. However, successful applicants should be working in a research environment capable of supporting potentially high impact prostate cancer research. Access to and interaction with a clinical environment and translational prostate cancer physician-scientists is highly desirable.

Application Deadline: April 16

For more information, please click here.


CASE CCC MEMBER PUBLICATION– American Journal of Gastroenterology

Congratulations to Cancer Center members Amitabh Chak, MD, Nathan Berger, MD, and Li Li, MD, PhD, whose article, "Carbohydrate Consumption and Esophageal Cancer: An Ecological Assessment" was published in the March 2008 issue of the American Journal of Gastroenterology. To view the abstract, please click here.


MARK YOUR CALENDARS– Cancer Immunology and Immunotherapy: Realizing the Promise

September 11-12
National Institutes of Health
Bethesda, MD

The Center for Cancer Research (CCR) at the National Cancer Institute will be hosting a two-day, national symposium entitled Cancer Immunology and Immunotherapy: Realizing the Promise. This meeting will host leaders in the field of cancer immunology and immunotherapy, include recent advances in both translational and clinical research, and should provide an exciting forum for discussion and debate on promising immunologic approaches to prevent and treat cancer.

Registration is free, but seating is limited so be sure to register early! Abstracts are being accepted for the poster session. Deadline for abstract submission is July 15.

For more information, please click here.


MARK YOUR CALENDARS– AACR Conference: Cancer Epigenetics

May 28-31
Boston Park Plaza Hotel
Boston, Massachusetts

This AACR special conference on cancer epigenetics will assemble prominent investigators in the field to discuss recent advances in this rapidly moving area. Sessions will review mechanisms and recent advances in whole genome epigenetic analysis of cancer. Several sessions will examine specific clinical applications such as diagnostics and therapeutics, and workshops will discuss practical research and translational issues such as methods of whole genome epigenetic analysis and definition of hypermethylator phenotypes. Ample time has been reserved for discussion, oral presentation of selected submitted abstracts, and late breaking research. This conference will provide a unique forum to review the remarkable progress in this area over the past few years, and provide a glimpse of where the field is moving, with a strong emphasis on translational epigenetics research.

Advance Registration Deadline: April 21

For details and registration information, please click here.

EVENTS

**All events are open to anyone interested in attending

April 7

Cancer Genetics/ Biology Journal Club
Geqiang Li, PhD
Research Associate, Bunting Lab
Division of Hem/Onc
CWRU/ UH
Topic: Stat5 in Abnormal Hematopoiesis
12:00 pm WRB 2-136

Pathology Seminar
John Lowe, MD
Professor, Pathology
CWRU/ UH
Topic: Glycan-Protein Interactions in the Control of Immunity
12:00 pm WRB 1413

Skeletal Research Center Seminar
Nora Singer, MD
Associate Professor, Pediatrics-Rheumatology
CWRU/ UH
Topic: Immune Targets & Arthritis
4:00 pm 123 Millis


April 8


April 9

Grand Rounds cancelled


April 10

Taussig Cancer Center Core Curriculum Series
Steve Smith, MD
Taussig Cancer Center
Cleveland Clinic
Topic: Molecular Pathogenesis of Non-Hodgkin Lymphoma
12:00 pm R3-002 Cleveland Clinic

Biochemistry Seminar
Xiang-Jiao Yang, PhD
Molecular Oncology Group
McGill University
Topic: Protein Lysine Acetylation: Epigenetic and Signaling Links to Leukemia and Heart Diseases
12:00 pm SOM W428

Neurosciences Seminar
Bruce Lamb, PhD
Associate Professor, Genetics
CWRU/ Cleveland Clinic
Topic: Mechanisms Underlying Neuronal Cell Cycle Abnormalities Observed in Alzheimer's Disease
12:10 pm BRB 105

Aging-Cancer Research Seminar
Cynthia Owusu, MD
Assistant Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Predictors of Tamoxifen Discontinuation Among Older Women With Estrogen Receptor Positive Breast Cancer
4:00 pm BRB 732


April 11

Cancer Center Seminar Series/ Blood Club cancelled

Hematology/Oncology Fellows
Steven Bernstein, MD
Associate Professor, Medicine- Hem/ Onc
University of Rochester
Topic: How to Get the T-Cells to Beat Up the B-Cells
8:00 am Wearn 137

Taussig Cancer Center Grand Rounds
Pramod Mistry, MD, PhD
Professor, Pediatrics & Internal Medicine
Yale University
Topic: A 69 Year Old Man With Type 1 Gaucher Disease & Multiple Myeloma-Expanding Spectrum of Phenotype in a Lysomal Disease
8:00 am Cleveland Clinic R3/002-003

more

For a complete listing of LRI seminars click here.


MARK YOUR CALENDARS:

UPCOMING CANCER CENTER SYMPOSIUMS

**For more information on these symposiums, please contact Christine Rhoads.

Update on Cervical Cancer Prevention: New Technology, New Evidence, and New Recommendations
April 18
Ritz Carlton Cleveland
Course Directors: Stephen Waggoner, MD and Kristine Zanotti, MD
Brochure and Registration

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood
Course Directors: Janice Lyons, MD, Halle Moore, MD, and Paula Silverman, MD
Brochure and Registration

Head and Neck Conference
October 31
Holiday Inn, Independence
Details to follow


NCI Cancer Bulletin

Featured Article
Gene Signatures Enhance Breast Cancer Risk Estimates

Cancer Research Highlights
Trial Suggests HRT Increases Breast Cancer Recurrence Risk

Vaccine Treats Breast Tumors in Mice

Guidelines for Colonoscopy Follow-up Assessed

Oncogene Identified in Diffuse Large B-Cell Lymphoma

Director's Highlight
Expanding the Role of Advocates in Shaping, Enhancing Cancer Research


MARK YOUR CALENDAR– AACR Annual Meeting 2008

The Case CCC has 62 members participating in 57 presentations at the American Association for Cancer Research (AACR) Annual Meeting scheduled for April 12-16 in San Diego, CA. In addition, Dr. Balazs Halmos is Chairperson of the Minisymposium, Molecular Markers for Cancer Diagnosis and Determination of Patient Outcomes on April 15. To view the Meeting Program, please click here.


FUNDING OPPORTUNITY– V Foundation

The Case CCC has been invited to submit ONE application for the V Foundation Translational Grant. The purpose of this grant is to develop novel approaches to the prevention, detection and treatment of human cancer that requires collaboration of investigators from both the lab and the clinic.

If you are interested in applying, please submit abstract, biosketch and budget to Gillian Irwin (gmi@case.edu) by Tuesday, April 15. The full application of the selected team is due to the V Foundation by June 16.


FUNDING OPPORTUNITY– TREC

The Case Center for Transdisciplinary Research on Energetics and Cancer and the Case Comprehensive Cancer Center invite investigators to submit developmental projects in the area of nutrition, energetics, energy balance, obesity, physical activity and cancer. These projects should provide an avenue for introducing and integrating new investigators and innovative technologies, methodologies, and/or research in the TREC infrastructure.

Pilot projects can be funded though a maximum of $50,000 per year, direct cost and should be planned to lead to independent research funding preferably of the NIH R01 type.

Please send original application via e-mail to lcc3@case.edu by Thursday, May 1.

To view the RFA, please click here. To view the Application Facepage, please click here.


CASE CCC 2008 RETREAT

The Case CCC 2008 Retreat is scheduled for July 11-12 at Sawmill Creek Resort in Huron, Ohio. The 235-acre resort has many features, including an 18-hole golf course, charter fishing on a Lake Erie marina, restaurants, shops, indoor/outdoor pools, exercise room and tennis courts. Nearby is Cedar Point, wineries, the Lake Erie Islands, and Maritime Museums.

Details and an agenda will be circulated soon.


RACE FOR THE PLACE- Join Our Team!

The Case Comprehensive Cancer Center has created a team for the Race for the Place, a fundraiser that benefits The Gathering Place in Beachwood, Ohio.

For those of you that are not familiar with the Gathering Place, it is a support center providing programs and services free of charge for individuals and families touched by cancer.

Each year, the first Sunday in June (June 1, 2008) is National Cancer Survivors' Day. On this day, The Gathering Place hosts a 5K / 1 Mile event called Race for the Place. This event helps to raise the money that allows The Gathering Place to offer all of their services free of charge.

If you want to join the Case CCC team, please click here or email gillian.irwin@case.edu. Family and friends are also welcome to join our team! It really is a great experience for everyone who is involved.


MARK YOUR CALENDARS– NIH Symposium: Challenges & Promise of Cell-Based Therapies

May 6, 2008
Natcher Conference Center, NIH
Bethesda, MD

Mark your calendars for the upcoming NIH Symposium: Challenges & Promise of Cell-Based Therapies on May 6. A small group of outstanding scientists will discuss productive new directions for research in regenerative medicine and highlight the state-of-the-science, notable milestones, and general impediments to cell-based therapies. Don't miss out on this opportunity to learn from and network with some of the best experts in the field of regenerative medicine.

Please register by April 18, 2008, as a large number of attendees is expected and seating is limited. There is a $30 registration fee to attend. For more information and to register, please click here.


MARK YOUR CALENDARS–AACR Accelerating Anticancer Agent Development and Validation Workshop

June 18-20, 2008
North Bethesda, MD

This is a postgraduate workshop for clinical and translational investigations focused on strategic planning to develop and validate new anticancer and cancer prevention agents and pathways. This is an intensive and interactive workshop in how to design effective strategies– from clinical trial initiative, to enabling trials, to pivotal efficacy trials– to develop new anticancer and prevention agents, taught by a distinguished faculty from across the academic, industry, consumer, and government (FDA) sectors.

For more information, click here.



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

DOD BCRP Idea Award
Pre-App/LOI Deadline: April 16

DOD BCRP Impact Award
Pre-App/LOI Deadline: April 16

DOD BCRP Synergistic Idea Award
Pre-App/LOI Deadline: April 16

William Bingham Foundation
Deadline: April 30

HHMI Early Career Scientist Competition
Mandatory LOI Deadline: April 30

DOD PCRP Idea Development Award
Pre-App/LOI Deadline: May 22

DOD PCRP New Investigator Award
Pre-App/LOI Deadline: May 22

DOD PCRP Prostate Cancer Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Physician Research Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Collaborative Undergraduate HBCU Student Summer Training Program Award Award
Pre-App/LOI Deadline: May 22

DOD PCRP Synergistic Idea Development Award
Pre-App/LOI Deadline: May 22

Administrative Supplements for Making Knockout Mice
Deadline: April 1 and June 1

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 2

DOD PRMRP Investigator-Initiated Research Award
Pre-App Deadline: June 4

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Pre-App Deadline: June 4

DOD PRMRP Translational Research Award
Pre-App Deadline: June 4

DOD PRMRP Advanced Technology/Therapeutic Development Award
Pre-App Deadline: June 4

DOD PRMRP Clinical Trial Award
Pre-App Deadline: June 4

DOD PCRP Clinical Consortium Agreement
Pre-App/LOI Deadline: June 11

DOD PCRP Clinical Trial Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Research Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Training Award
Pre-App/LOI Deadline: June 11

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
Pre-App/LOI Deadline: June 11

DOD OCRP Consortium Development Award
Pre-Application Deadline: June 25

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
LOI Deadline: June 30

DOD PRMRP Investigator-Initiated Research Award
Proposal Deadline: July 2

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Proposal Deadline: July 2

DOD PRMRP Translational Research Award
Proposal Deadline: July 2

DOD PRMRP Advanced Technology/Therapeutic Development Award
Proposal Deadline: July 2

DOD PRMRP Clinical Trial Award
Proposal Deadline: July 2

DOD OCRP Consortium Development Award
Proposal Deadline: July 9

Doris Duke CSDA Bridge Grant
Deadline: September 1


NIH Bulletin – Notices and Funding Opportunities

NIH Announces New Centralized Processing Center for Receipt of Grant Closeout Documents and Reminds Grantees of Required Closeout Reports for NIH Assistance Awards (NOT-OD-08-061)

Enhancing Tumoricidal Activity of Natural Killer (NK) Cells by Dietary Components for Cancer Prevention (R01) (PA-08-131)

Enhancing Tumoricidal Activity of Natural Killer (NK) Cells by Dietary Components for Cancer Prevention (R21) (PA-08-132)

Correlative Studies with Specimens from Multi-Site Trials (R21) (PA-08-133)

Correlative Studies with Specimens from Multi-Site Trials (R01) (PA-08-134)

Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies of Humans (R21) (PAR-08-135)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.green@uhhospitals.org
 
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