Case Comprehensive Cancer Center Newsletter

April 21, 2008

MARK YOUR CALENDARS– Ohio Collaborative Conference on Bioinformatics

June 2-4, 2008
University of Toledo
Toledo, Ohio

The Third Annual Ohio Collaborative Conference on Bioinformatics will be held at the University of Toledo June 2-4. This conference will provide an interdisciplinary forum for discussing approaches, research findings, and experiences regarding computational investigations of biological problems. An important goal of the conference continues to be the fostering of long-term collaborative relationships among informatics and life sciences researchers from academia, government and industry, spanning Ohio and adjacent states. This meeting is not only for experts in bioinformatics, but also for those who make substantial use of bioinformatic tools in their research/development work, or would like to expand such use.

Abstract Submission Deadline: April 27

For more information, please click here.


MARK YOUR CALENDARS– ASCO Annual Meeting

May 30 - June 3
McCormick Place
Chicago, IL

The American Society of Clinical Oncology (ASCO) Annual Meeting is scheduled for May 30- June 3 in Chicago. This meeting is the premier scientific and educational event in oncology, drawing 30,000 attendees worldwide. As a forum for collaboration and communication, the ASCO Annual Meeting brings together oncologists of all disciplines, researchers, nurses, and patient advocates in the fight against cancer.The 2008 Meeting will unite the global oncology community with the common goals of delivering the highest quality patient care and innovating treatment advances.

Early Registration Deadline: April 25

For details, please click here.

If anyone is presenting at the Meeting, please let us know. As always, we are happy to publicize any news you have, such as major presentations, publications, awards, etc.


FUNDING OPPORTUNITY– Case CCC Request for Pilot Project Applications

The Case CCC is currently accepting applications for a "Multi-Investigator Grant Initiative to Promote the Basic Science Scientific Focus Group Areas of the Cancer Center". Awards of up to $50,000 for 1 year are available.

Principal Investigators must be full-time members of the faculty at Case Western Reserve University or Cleveland Clinic Lerner College of Medicine and members of the Case Comprehensive Cancer Center.

Application Deadline: May 27

To view the RFA, please click here. RFA, Instructions and Cover Sheet are also available on the Cancer Center homepage.


FUNDING OPPORTUNITY– Dana Foundation Brain and Immuno-Imaging Grant Program

CWRU SOM has been invited to submit TWO applications (one per Track A and Track B) to the Dana Foundation Brain and Immuno-Imaging Grant Program- Round 2 2008 (Using Brain and Immune Imaging Innovations to Improve Human Health).

The Dana Foundation supports research on imaging innovations that help reveal how the human brain functions normally, how disorders and injuries alter these functions, and how various therapies affect these conditions. Since immune cells are often integrally involved in the development of, protection against, or responses to brain diseases and injuries, funded research also can focus on immune cell interactions with brain cells. The Program is designed to enable investigators to obtain pilot data more quickly than is possible through other funding processes. Investigations must be applicable to human brain or brain-immune functioning or malfunctioning to be considered for funding.
Track A: Conventional imaging of anatomical or physiological brain functioning and should involve patient-oriented clinical research.
Track B: Cellular and molecular imaging and should have direct clinical relevance--should focus on the biological activities of human brain cells, or their interactions with immune cells in health and disease. These studies may involve human tissues or animal models.

Internal Deadline: April 24
External Deadline: May 20

Internal Contact: Richard Sohn, PhD richard.sohn@case.edu; 368-1158

If you are interested in applying, the following documents required:
1. Full CV with funding history
2. 1-2 page proposal with specific aims, and
3. Letter of support from your Chair
Send materials electronically to Richard.sohn@case.edu (please ONE document if feasible)

For details including eligibility requirements, please click here.


FUNDING OPPORTUNITY– TREC

The Case Center for Transdisciplinary Research on Energetics and Cancer and the Case Comprehensive Cancer Center invite investigators to submit developmental projects in the area of nutrition, energetics, energy balance, obesity, physical activity and cancer. These projects should provide an avenue for introducing and integrating new investigators and innovative technologies, methodologies, and/or research in the TREC infrastructure.

Pilot projects can be funded though a maximum of $50,000 per year, direct cost and should be planned to lead to independent research funding preferably of the NIH R01 type.

Please send original application via e-mail to lcc3@case.edu by Thursday, May 1.

To view the RFA, please click here. To view the Application Facepage, please click here.


MARK YOUR CALENDARS– Cancer Immunology and Immunotherapy: Realizing the Promise

September 11-12
National Institutes of Health
Bethesda, MD

The Center for Cancer Research (CCR) at the National Cancer Institute will be hosting a two-day, national symposium entitled Cancer Immunology and Immunotherapy: Realizing the Promise. This meeting will host leaders in the field of cancer immunology and immunotherapy, include recent advances in both translational and clinical research, and should provide an exciting forum for discussion and debate on promising immunologic approaches to prevent and treat cancer.

Registration is free, but seating is limited so be sure to register early! Abstracts are being accepted for the poster session. Deadline for abstract submission is July 15.

For more information, please click here.


NCI CANCER BULLETIN

Featured Article
Drug Combination Cuts Risk of Advanced Colon Polyps

Cancer Research Highlights
Mutant Gene Linked to Aggressive Leukemia

Chromosome Region Linked to Lung Cancer

IV Iron Effective in Treating Chemotherapy-Induced Anemia

Featured Clinical Trial
Herbal Care for Brain Cancer
Phase II Randomized Study of Adjuvant Boswellia Serrata and Standard Treatment Versus Standard Treatment Alone in Patients with Newly Diagnosed or Recurrent High-Grade Gliomas (CASE-CCF-7348)
PI: Dr. Glen Stevens, Cleveland Clinic

Director's Update
At AACR, New Science and an Important Dialogue
Pay special attention to the section on the recommendations from the Translational Research Working Group. There is a current effort to link SPORES to the translational research network and to stratify funding by score.

EVENTS

**All events are open to anyone interested in attending

April 21

Cancer Genetics/ Biology Journal Club
Peter Haviernik, PhD
Instructor, Laughlin Lab, Division of Hem/Onc
CWRU/ UH
Topic: NFAT1 in Leukemogenesis
12:00 pm WRB 2-136

Pathology Seminar
Mark Jackson, PhD
Assistant Professor, Pathology
CWRU
Topic: Forward Genetics and Cancer Signaling: Identifying Genes Involved in Human Mammary Epithelial Cell Transformation
12:00 pm WRB 1413

Physiology & Biophysics Seminar
Harry Gill, PhD
Visiting Assistant Professor, Physiology & Biophysics
CWRU
Topic: Crystal Structure Determination of the N-Terminal Domains of the SLC4 Family Members and their Binding Partners
4:00 pm SOM W203


April 22


April 23

Grand Rounds
Henry Koon, MD
Assistant Professor, Medicine- Hem/Onc
CWRU/ UH
Topic: Melanoma: Current and Future Treatment Strategies
8:00 am Lerner B-151

Physiology & Biophysics Seminar
Eric Olson, PhD
Professor, Molecular Biology
University of Texas Southwestern Medical Center
Topic: MicroRNAs as Regulators of Heart Development and Disease
12:15 pm BRB 105


April 24

Dermatology Grand Rounds
Michael Detmar, MD
Professor, Pharmacogenomics
Institute of Pharmaceutical Sciences
Swiss Federal Institute of Technology
Topic: The Cutaneous Vasculature- A New Therapeutic Target
9:30 am WRB 1413

Taussig Cancer Center Core Curriculum Series
Ann Tan, MD
Taussig Cancer Center
Topic: Mesethelioma
12:00 pm R3-002 Cleveland Clinic

Pharmacology Seminar: Faculty Recruitment Series
Youwei Zhang, PhD
Senior Research Associate, Tony Hunter Lab
Salk Institute
Topic: Turn On and Off the Replication Checkpoint
12:00 pm SOM W331

Neurosciences Seminar
Michael Goldberg, MD
Professor of Brain & Behavior, Neuroscience, Neurology, Psychiatry, Ophthalmology
Columbia University
Topic: On the Agnosticism of Spikes: Saccades, Salience and Attention in the Lateral Intraparietal Area
12:10 pm BRB 105

Case CCC Special Lecture
William Hahn, MD, PhD
Associate Professor, Medical Oncology
Dana-Farber Cancer Institute
Topic: Functional Genomics, Experimental Models and Cancer
3:00 pm BRB 105

Aging-Cancer Research Seminar
Peter Harte, PhD
Professor, Genetics
CWRU
Topic: Chromatin-Mediated Gene Silencing Mechanisms and Their Modulation: Implications for Aging and Cancer
4:00 pm BRB 732


April 25

Hematology/Oncology Fellows
Priya Jain, MD
Fellow, Division of Hem/Onc
CWRU/ UH
Topic: Amyloidosis
8:00 am Wearn 137

Taussig Cancer Center Grand Rounds
William Hahn, MD, PhD
Associate Professor, Medical Oncology
Dana-Farber Cancer Institute
Topic: Functional Genomics, Experimental Models, and Cancer Target Discovery and Validation
8:00 am Cleveland Clinic R3/002-003

Cancer Center Seminar Series/ Blood Club
Richard J. Jones, MD
Professor, Oncology and Medicine
Johns Hopkins University
Topic: Cancer Stem Cells- Are We Missing the Target?
12:00 pm BRB 105

Inaugural James S. Winshall, MD '92 Memorial Lectureship
JudyAnn Bigby, MD
Secretary of Health and Human Services
Commonwealth of Massachusetts
Topic: Who Will Take Care of the Patient? The Role of Primary Care
4:00 pm BRB 105

more

For a complete listing of LRI seminars click here.


MARK YOUR CALENDARS:

UPCOMING CANCER CENTER SYMPOSIUMS

**For more information on these symposiums, please contact Christine Rhoads.

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood
Course Directors: Janice Lyons, MD, Halle Moore, MD, and Paula Silverman, MD
Brochure and Registration

ASCO Review 2008
June 27
InterContinental Hotel & Bank of America Conference Center
Course Directors: Robert Dreicer, MD and Hillard Lazarus, MD
Brochure and Registration

Head and Neck Conference
October 31
Holiday Inn, Independence
Details to follow


MARK YOUR CALENDARS– AACR Conference: Cancer Epigenetics

May 28-31
Boston Park Plaza Hotel
Boston, Massachusetts

This AACR special conference on cancer epigenetics will assemble prominent investigators in the field to discuss recent advances in this rapidly moving area. Sessions will review mechanisms and recent advances in whole genome epigenetic analysis of cancer. Several sessions will examine specific clinical applications such as diagnostics and therapeutics, and workshops will discuss practical research and translational issues such as methods of whole genome epigenetic analysis and definition of hypermethylator phenotypes. Ample time has been reserved for discussion, oral presentation of selected submitted abstracts, and late breaking research. This conference will provide a unique forum to review the remarkable progress in this area over the past few years, and provide a glimpse of where the field is moving, with a strong emphasis on translational epigenetics research.

Advance Registration Deadline: April 21

For details and registration information, please click here.


MARK YOUR CALENDARS– AACR Centennial Conference

July 20-23
Hyatt Regency Monterey
Monterey, California

The AACR Centennial Conference on Translational Cancer Medicine 2008: Cancer Clinical Trials and Personalized Medicine is the second in the AACR Centennial Conference series on Translational Cancer Medicine and the first to be held in the United States. Translational research is a key programmatic priority of the AACR, and this meeting will showcase the latest scientific discoveries from the laboratory and their clinical applications.

Deadline for abstract submission, award opportunities, and early registration is May 2.

For more information, please click here.


CASE CCC 2008 RETREAT

The Case CCC 2008 Retreat is scheduled for July 11-12 at Sawmill Creek Resort in Huron, Ohio. The 235-acre resort has many features, including an 18-hole golf course, charter fishing on a Lake Erie marina, restaurants, shops, indoor/outdoor pools, exercise room and tennis courts. Nearby is Cedar Point, wineries, the Lake Erie Islands, and Maritime Museums.

Details and an agenda will be circulated soon.


RACE FOR THE PLACE- Join Our Team!

The Case Comprehensive Cancer Center has created a team for the Race for the Place, a fundraiser that benefits The Gathering Place in Beachwood, Ohio.

For those of you that are not familiar with the Gathering Place, it is a support center providing programs and services free of charge for individuals and families touched by cancer.

Each year, the first Sunday in June (June 1, 2008) is National Cancer Survivors' Day. On this day, The Gathering Place hosts a 5K / 1 Mile event called Race for the Place. This event helps to raise the money that allows The Gathering Place to offer all of their services free of charge.

If you want to join the Case CCC team, please click here or email gillian.irwin@case.edu. Family and friends are also welcome to join our team! It really is a great experience for everyone who is involved.

If cannot run the race, but would still like to help, please consider making a small donation to sponsor our team. Every little bit helps. To sponsor us, please click here.


MARK YOUR CALENDARS– NIH Symposium: Challenges & Promise of Cell-Based Therapies

May 6, 2008
Natcher Conference Center, NIH
Bethesda, MD

Mark your calendars for the upcoming NIH Symposium: Challenges & Promise of Cell-Based Therapies on May 6. A small group of outstanding scientists will discuss productive new directions for research in regenerative medicine and highlight the state-of-the-science, notable milestones, and general impediments to cell-based therapies. Don't miss out on this opportunity to learn from and network with some of the best experts in the field of regenerative medicine.

Please register by April 18, 2008, as a large number of attendees is expected and seating is limited. There is a $30 registration fee to attend. For more information and to register, please click here.


MARK YOUR CALENDARS–AACR Accelerating Anticancer Agent Development and Validation Workshop

June 18-20, 2008
North Bethesda, MD

This is a postgraduate workshop for clinical and translational investigations focused on strategic planning to develop and validate new anticancer and cancer prevention agents and pathways. This is an intensive and interactive workshop in how to design effective strategies– from clinical trial initiative, to enabling trials, to pivotal efficacy trials– to develop new anticancer and prevention agents, taught by a distinguished faculty from across the academic, industry, consumer, and government (FDA) sectors.

For more information, click here.



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

NIH/Fogarty International Clinical Research Fellowships
Deadline: April 30

William Bingham Foundation
Deadline: April 30

HHMI Early Career Scientist Competition
Mandatory LOI Deadline: April 30

DOD PCRP Idea Development Award
Pre-App/LOI Deadline: May 22

DOD PCRP New Investigator Award
Pre-App/LOI Deadline: May 22

DOD PCRP Prostate Cancer Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Physician Research Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Collaborative Undergraduate HBCU Student Summer Training Program Award Award
Pre-App/LOI Deadline: May 22

DOD PCRP Synergistic Idea Development Award
Pre-App/LOI Deadline: May 22

Administrative Supplements for Making Knockout Mice
Deadline: April 1 and June 1

Damon Runyon-Rachleff Innovation Award
Pre-Proposal Deadline: June 2

DOD PRMRP Investigator-Initiated Research Award
Pre-App Deadline: June 4

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Pre-App Deadline: June 4

DOD PRMRP Translational Research Award
Pre-App Deadline: June 4

DOD PRMRP Advanced Technology/Therapeutic Development Award
Pre-App Deadline: June 4

DOD PRMRP Clinical Trial Award
Pre-App Deadline: June 4

DOD PCRP Clinical Consortium Agreement
Pre-App/LOI Deadline: June 11

DOD PCRP Clinical Trial Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Research Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Training Award
Pre-App/LOI Deadline: June 11

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
Pre-App/LOI Deadline: June 11

DOD OCRP Consortium Development Award
Pre-Application Deadline: June 25

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
LOI Deadline: June 30

DOD PRMRP Investigator-Initiated Research Award
Proposal Deadline: July 2

DOD PRMRP Investigator-Initiated Research Award (Specific appropriation for bone marrow failure disorder research)
Proposal Deadline: July 2

DOD PRMRP Translational Research Award
Proposal Deadline: July 2

DOD PRMRP Advanced Technology/Therapeutic Development Award
Proposal Deadline: July 2

DOD PRMRP Clinical Trial Award
Proposal Deadline: July 2

DOD OCRP Consortium Development Award
Proposal Deadline: July 9

Doris Duke CSDA Bridge Grant
Deadline: September 1


NIH Bulletin – Notices and Funding Opportunities

May IACUC 101 & 201 PLUS Workshops in Delray Beach, Florida (NOT-OD-08-067)

NIH Support for Conferences and Scientific Meetings (Parent R13/U13) (PA-08-149)

Midcareer Investigator Award in Patient-Oriented Research (K24) (PA-08-151)

Academic Career Award (K07)(PA-08-152)

Quick-Trials for Imaging and Image-Guided Interventions: Exploratory Grants (R21)(PAR-08-147)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.green@uhhospitals.org
 
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