Case Comprehensive Cancer Center Newsletter

March 17, 2008

MARK YOUR CALENDARS– NIH Symposium: Challenges & Promise of Cell-Based Therapies

May 6, 2008
Natcher Conference Center, NIH
Bethesda, MD

Mark your calendars for the upcoming NIH Symposium: Challenges & Promise of Cell-Based Therapies on May 6, 2008. A small group of outstanding scientists will discuss productive new directions for research in regenerative medicine and highlight the state-of-the-science, notable milestones, and general impediments to cell-based therapies. Don't miss out on this opportunity to learn from and network with some of the best experts in the field of regenerative medicine.

Please register by April 18, 2008, as a large number of attendees is expected and seating is limited. There is a $30 registration fee to attend. For more information and to register, please click here.

FUNDING OPPORTUNITY– HHMI Early Career Scientist Competition

The Howard Hughes Medical Institute (HHMI) has announced a new Early Career Scientist Program. Through a national competition, HHMI hopes to appoint approximately 70 early career scientists from biological and medical areas.

Applicant must have between two and six years of experience since first appointed as assistant professor or equivalent position. To meet this requirement, applicant's first faculty position as assistant professor must have begun no earlier than June 1, 2002 and no later than September 1, 2006.

Applicant may hold one or more research grants but may not hold more than one early career award. Applicant cannot be appointed as an HHMI early career scientist if he/she will continue to have administrative responsibilities or other nonresearch duties that would preclude devoting a minimum of 75% of total effort to the direct conduct of research.

Mandatory LOI Deadline: April 30
Application Deadline: June 10

For more information, please click here.


An editorial written by Drs. Afshin Dowlati and Pingfu Fu was published in the March 10 issue of the Journal of Clinical Oncology (JCO). To view this editorial, entitled, "Is Response Rate Relevant to the Phase II Trial Design of Targeted Agents?", click here.


The following Cancer Center members have been appointed to American Society of Hematology (ASH) committees:

Kenneth Cooke, MD –Associate Professor, Medicine- Hem/Onc
Appointed Member, Scientific Committee on Transplantation Biology, 2008-2011

Clark Distelhorst, MD –Professor, Medicine- Hem/Onc, Pharmacology
Appointed Member, Scientific Committee on Immunology & Host Defense, 2007-2010

Stanton L. Gerson, MD –Director, Case CCC; Professor, Medicine- Hem/Onc
Appointed Member, Committee on Investment and Audit, 2008-2010

Mikkael A. Sekeres, MD –Assistant Professor, Hematology & Medical Oncology
Appointed Member, Committee on Educational Affairs, 2008-2011

Roy L. Silverstein, MD –Professor, Cell Biology
Ad Hoc Member, Executive Committee, 2005-2008
Chair, Committee on Government Affairs, 2005-2008
Appointed Member, Documentary Oversight Subcommittee, 2007-2008
Liaison, Committee on Practice, 2005-2008
Liaison, Committee on Training Programs, 2005-2008


News from NCI
The Nation's Investment in Cancer Research Connecting the Cancer Community: An Annual Plan and Budget Proposal for FY2009

The Early Detection Research Network (EDRN): Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk

Health Disparities Across the Cancer Continuum: A Supplement Sponsored by the National Cancer Institute

NCI Debuts New Easy to Read Radiation Therapy Educational Resources

News from NIH
Enzyme Structure Reveals New Drug Targets for Cancer and Other Diseases

News from Other Federal Agencies
National Business Group on Health and HHS Office of Minority Health Launch Initiative to Reduce Racial and Ethnic Disparities

United States Cancer Statistics: 2004 Incidence and Mortality

FDA Extends Avastin's Use to Breast Cancer

MARK YOUR CALENDARS– Midwest Blood Club Annual Meeting

April 3, 2008
Ohio State University
Columbus, Ohio

The VI Midwest Blood Club meeting will take place on Thursday, April 3 at the Biomedical Research Tower of the Ohio State University. There will be exceptional keynote speakers, including Stan Gerson from CWRU, Merv Yoder from Indiana University, and Scott Armstrong from Harvard. There will also be an afternoon poster session where you will have the opportunity to review many research updates. For those of you interested in submitting an abstract, it is acceptable to submit an abstract/poster you have utilized in another venue within the past six months. The abstract deadline is Friday, March 14. The final meeting agenda will be available by mid-March.

To view the Abstract Submission form click here. To view the Meeting Registration Form click here.

A block of rooms is reserved at the Blackwell Inn on the campus of Ohio State University. Please call 614-247-4000 for reservations. The cost is $129 per night. You may want to take advantage of also attending the International Society for Cellular Therapy meeting that will take place on April 4-5 at the Biomedical Research Tower.


**All events are open to anyone interested in attending

March 17

Cancer Genetics/ Biology Journal Club
David Wald, MD, PhD
Pathology Resident- Tse Lab
Division of Hem/Onc
Topic: Search for Novel AML Differentiation-inducing Agents
12:00 pm WRB 2-136

Skeletal Research Center Seminar
Brett Hoover
Graduate Student, Biology
Topic: Effects of Modulating Canonical Wnt Signaling on the In Vitro Performance of Human Bone Marrow-Derived Connective Tissue Progenitor Cells
4:00 pm 123 Millis

March 18

March 19

Developmental Therapeutics Meeting cancelled

Grand Rounds
Lois Friedman, PhD
Professor, Psychiatry
Topic: Self-Blame, Self-Forgiveness and Spirituality: Correlates of Mood and Quality of Life in Women with Breast Cancer
8:00 am Lerner B-151

Neurosurgery Grand Rounds
Gene Barnett, MD
Professor, Neurological Surgery
CWRU/ Cleveland Clinic
Topic: Evolution of Gamma Knife Radiosurgery
7:30 am TT1-100 Cleveland Clinic

March 20

Taussig Cancer Center Core Curriculum Series
Khaldoun Almhanna, MD, MPH
Taussig Cancer Center
Cleveland Clinic
Topic: Overview of Anal Cancer
12:00 pm R3-002 Cleveland Clinic

Cancer Prevention & Control Seminar
Catherine Demko, PhD
Assistant Professor, Community Dentistry
Topic: Oral Cancer Screening in Dental Offices
3:30 pm Wearn 137

TREC Seminar
Cheryl Thompson, PhD
Senior Research Associate, Family Medicine
Topic: The Retinol Binding Protein-4 Pathway and Colon Neoplasia
4:00 pm BRB 732

Neurosciences Seminar
John Feng, PhD
Assistant Professor, Pharmacology
Topic: Dissecting the Genetic Mechanisms of Dopamine Neurotransmission Related Human Diseases Using C. Elegans
12:10 pm SOM E609 (please note room change)

March 21

Taussig Cancer Center Grand Rounds cancelled

Hematology/Oncology Fellows
Rom Leidner, MD
Fellow, Medicine- Hem/Onc
Topic: Liver Metastases in Colorectal Cancer
8:00 am Wearn 137

Cancer Center Seminar Series/ Blood Club
Nigel Mackman, PhD
Professor, Medicine- Hem/Onc
University of North Carolina, Chapel Hill
Topic: Hemostasis and Thrombosis
12:00 pm BRB 105


For a complete listing of LRI seminars click here.



**For more information on these symposiums, please contact Christine Rhoads.

Geriatric Oncology and Primary Care: Promoting Partnerships in Practice and Research
April 3-4
Dively Center
Course Directors: Nathan Berger, MD and Julia Rose, PhD
Brochure and Registration

Update on Cervical Cancer Prevention: New Technology, New Evidence, and New Recommendations
April 18
Ritz Carlton Cleveland
Course Directors: Stephen Waggoner, MD and Kristine Zanotti, MD
Brochure and Registration

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood
Course Directors: Janice Lyons, MD, Halle Moore, MD, and Paula Silverman, MD


The Case Comprehensive Cancer Center has created a team for the Race for the Place, a fundraiser that benefits the Gathering Place in Beachwood, Ohio.

For those of you that are not familiar with the Gathering Place, it is a support center providing programs and services free of charge for individuals and families touched by cancer.

Each year, the first Sunday in June (June 1, 2008) is National Cancer Survivors' Day. On this day, The Gathering Place hosts a 5K / 1 Mile event called Race for the Place. This event helps to raise the money that allows The Gathering Place to offer all of their services free of charge.

If you want to join the Case CCC team, please click here or email Family and friends are also welcome to join our team! It really is a great experience for everyone who is involved.

FUNDING OPPORTUNITY– American Cancer Society

The American Cancer Society (ACS) is accepting applications for the following funding opportunities:

  • Research Scholar Grants in Basic, Preclinical, Clinical, and Epidemiology Research

  • Research Scholar Grants in Cancer Control and Prevention: Psychosocial and Behavioral Research

  • Research Scholar Grants in Cancer Control and Prevention: Health Services and Health Policy Research

  • Postdoctoral Fellowships

  • Mentored Research Scholar Grants in Applied and Clinical Research

  • Research Professorships

  • Research Scholar Grant in the Role of Healthcare and Insurance in Improving Outcomes in Cancer Prevention, Early Detection and Treatment

Deadline for all above opportunities: April 1

For more information, please click here.

MARK YOUR CALENDAR– AACR Annual Meeting 2008

The American Association for Cancer Research (AACR) Annual Meeting is scheduled for April 12-16 in San Diego, CA. More than 17,000 participants from 60 countries will gather to discuss an estimated 6,000 abstracts and to hear more than 500 invited presentations on new and significant discoveries in basic, clinical, and translational cancer research. Scientific award lectures, grant writing workshops, networking events, and educational sessions will round out the comprehensive program.

For registration information and for more information, click here.

If anyone is presenting at the Meeting, please let us know. As always, we are happy to publicize any news you have, such as major presentations, publications, awards, etc.


The International Society for Cellular Therapy (ISCT) will be holding a regional meeting on April 4-5 at the Ohio State University Biomedical Research Tower in Columbus, Ohio. This meeting is targeted towards laboratory practitioners and technicians working in cellular therapy, and anyone interested in networking with cell therapy practitioners at a small, technically focused, reasonably priced meeting.

For more information, click here.

MARK YOUR CALENDARS–AACR Accelerating Anticancer Agent Development and Validation Workshop

June 18-20, 2008
North Bethesda, MD

This is a postgraduate workshop for clinical and translational investigations focused on strategic planning to develop and validate new anticancer and cancer prevention agents and pathways. This is an intensive and interactive workshop in how to design effective strategies– from clinical trial initiative, to enabling trials, to pivotal efficacy trials– to develop new anticancer and prevention agents, taught by a distinguished faculty from across the academic, industry, consumer, and government (FDA) sectors.

For more information, click here.

MARK YOUR CALENDARS– AACR Cancer Biostatistics Workshop

July 13 - 19, 2008
The Lodge at Sonoma
Sonoma, CA

Applications are now being accepted for the American Association for Cancer Research (AACR) Cancer Biostatistics Workshop, July 13-19, 2008 in Sonoma, California.

This is an intensive one-week workshop in statistical methods in oncology and collaborative interactions between biostatisticians and clinical oncologists. It is designed to update the expertise and increase the number of biostatisticians working on oncology-related problems to improve their ability to use new biological information, develop valid research designs for new therapies, and increase the number and quality of clinical trials.

Application Deadline: March 24

For details, please click here.


Robert Wood Johnson Foundation Harold Amos Medical Faculty Development Program
Deadline: March 19

Human Frontier Science Program
Pre-Registration Deadline: March 21

NIH Shared Instrumentation Grant Program
Deadline: March 24

Lance Armstrong Foundation Community Grants
Deadline: March 24

DOD OCRP Career Development Award– Postdoctoral Fellow or Early Career Investigator
Pre-Application LOI: March 26

DOD OCRP Idea Development Award
Pre-App/Pre-Proposal Deadline: March 26

DOD OCRP Translational Research Partnership Award
Pre-App/Pre-Proposal Deadline: March 26

DOD BCRP Clinical Translational Research Award
Pre-App/Pre-Proposal Deadline: March 27

DOD BCRP Era of Hope Postdoctoral Award
Pre-App/Nomination Deadline: March 27

DOD BCRP Era of Hope Scholar Award
Pre-App/Nomination Deadline: March 27

DOD BCRP HBCU/MI Partnership Training Award
Pre-App/Pre-Proposal Deadline: March 27

DOD BCRP Innovator Award
Pre-App/Nomination Deadline: March 27

Cancer Research Institute
Deadline: April 1

Administrative Supplements for Making Knockout Mice
Deadline: April 1 and June 1

SASS Foundation
Deadline: April 1

Human Frontier Science Program
LOI Deadline: April 2

DOD BCRP Idea Award
Pre-App/LOI Deadline: April 16

DOD BCRP Impact Award
Pre-App/LOI Deadline: April 16

DOD BCRP Synergistic Idea Award
Pre-App/LOI Deadline: April 16

William Bingham Foundation
Deadline: April 30

DOD PCRP Idea Development Award
Pre-App/LOI Deadline: May 22

DOD PCRP New Investigator Award
Pre-App/LOI Deadline: May 22

DOD PCRP Prostate Cancer Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Physician Research Training Award
Pre-App/LOI Deadline: May 22

DOD PCRP Collaborative Undergraduate HBCU Student Summer Training Program Award Award
Pre-App/LOI Deadline: May 22

DOD PCRP Synergistic Idea Development Award
Pre-App/LOI Deadline: May 22

Administrative Supplements for Making Knockout Mice
Deadline: April 1 and June 1

DOD PCRP Clinical Consortium Agreement
Pre-App/LOI Deadline: June 11

DOD PCRP Clinical Trial Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Research Award
Pre-App/LOI Deadline: June 11

DOD PCRP Health Disparity Training Award
Pre-App/LOI Deadline: June 11

DOD PCRP Laboratory-Clinical Transition Award: Stage 1
Pre-App/LOI Deadline: June 11
LOI Deadline: June 30

NIH Bulletin – Notices and Funding Opportunities

Pilot Studies in Pancreatic Cancer (PA-06-314)

Cancer Surveillance Using Health Claims-based Data System (R21) (PA-06-386)

Academic-Industrial Partnerships for Development and Validation of In Vivo Imaging Systems and Methods for Cancer Investigations (R01) (PAR-07-214)

New Frequently Asked Questions Added to OLAW Web Page (NOT-OD-08-058)

Amendment to PAR-07-214: Academic-Industrial Partnerships for Development and Validation of In Vivo Imaging Systems and Methods for Cancer Investigations (R01) (NOT-CA-08-014)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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