Case Comprehensive Cancer Center Newsletter

February 4, 2008

FUNDING OPPORTUNITY – Leukemia Research Foundation

The Leukemia Research Foundation is currently accepting applications for New Investigator Grants. New investigators are considered to be within seven (7) years of their first independent position. Years as a resident physician, fellow physician, or post-doctoral fellow are considered to be training years. Investigators with a research associate, research assistant or similar position, must include a letter from the department chair confirming their position is independent. In addition, the applicant must state how their research is independent from others at their institution. Applicants with an NIH K08 or K23 are NOT excluded.

Investigators with NIH R01 funding, VA Merit Award or equivalent are ineligible to apply. Anyone with funding from other national foundations, career development awards (ACS, ASH, etc.), any outside funding that is in excess of $125,000 per year, excluding startup funds are also ineligible.

Deadline: February 15

For more information, click here.

FUNDING OPPORTUNITY –ACS Joseph S. Silber Fellowship

The purpose of the American Cancer Society Joseph S. Silber Fellowship is to expose students to the burden of cancer with the intent that cancer research will become a lifelong interest and/or pursuit. This fellowship is open to all undergraduate and graduate students who are attending an institution in or around Cuyahoga County, Ohio which trains research fellows and has established training programs in the areas of basic or clinical research.

Deadline: March 14

For details, click here.

FUNDING OPPORTUNITY –Burroughs Wellcome Fund Career Awards at the Scientific Interface (CASI)

Career Awards at the Scientific Interface (CASI) are intended to foster the early career development of postdoctoral scientists with backgrounds in the physical/computational sciences whose work addresses biological questions and who are dedicated to pursuing a career in academic research. Applicants are expected to draw upon their training in a scientific field other than biology to propose innovative approaches to answer important questions in the biological sciences. Proposals that include experimental validation of theoretical models are particularly encouraged.

An institution (including its affiliated hospitals or research institutes) may nominate up to FOUR candidates. If the institution nominates more than two, then at least one of the candidates must be a female and at least one of the candidates must be a member of an underrepresented minority group**.

This is a multi-college funding opportunity. The SOM Proposal Selection Committee will review and rank submissions and forward to the Provost's Office. Final nominees will be selected by a review panel to be convened by Deputy Provost Lynn Singer.

Internal Deadline: February 13
External Deadline: April 15

  • Full C.V. with funding history (please include gender and race)**,
  • 1-2 page proposal with specific aims, and
  • Letter of support from your Chair.

Send materials electronically to (ONE document if feasible)

For details, please click here.

MARK YOUR CALENDARS – Best of San Antonio Breast Cancer Symposium

The Case Comprehensive Cancer Center is pleased to present the Best of San Antonio Breast Cancer Symposium on Wednesday, February 13 at the Embassy Suites Hotel in Independence, Ohio. This symposium is an international meeting of laboratory and clinical investigators, dedicated to the presentation of the latest research findings in breast cancer. Basic and translational studies that improve our understanding of breast cancer, as well as practice-changing clinical trials, are presented and discussed. The review course will summarize the highlights of the 2007 SABCS, with a focus on the clinical implications of the new information presented at this meeting.

Medical oncologists, breast surgeons, radiation oncologists, and other health care providers with an interest in the management of patients with breast cancer should attend this course.

For more information and to register, please click here.

There is no registration fee, but advanced registration is required. To register after February 11, please call (216) 444-7924.

MARK YOUR CALENDARS – CSCRM Pluripotency Meeting

On January 18th, the CSCRM circulated a query to determine your interest in meeting regarding pluripotency vectors, etc. There seems to be a considerable amount of interest. The first meeting to discuss this initiative will be at noon on Monday, February 11, in the Wolstein Board Room 2-505. Please plan to attend this meeting even if your interest was to be involved in only a portion of the initiative.

FUNDING OPPORTUNITY – William Bingham Foundation

The William Bingham Foundation, which makes grants to nonprofit organizations in Cleveland and other areas across the United States, is accepting applications for its 2008 funding priority, which is to assist organizations working to increase access to health care and services for low-income breast cancer patients, particularly in Cleveland, Ohio, and Washington, D.C. This focus is in effect only for 2008.

Qualifying organizations will have no prior relationship with the William Bingham Foundation, and projects should seek to improve healthcare access through public education, diagnosis, treatment, and other means. Program activities can include breast cancer prevention and education programs, medical services for low-income women diagnosed with breast cancer, and support services for low-income breast cancer patients.

The maximum grant amount is $25,000. The deadline for applications is April 30

For application instructions, click here.


Dear Colleagues,
Do you know of a good student or postdoctoral fellow who might be interested in working in my lab in the near future? We have some nice new results from experiments in which we use promoter insertional mutagenesis to generate mutant cell lines resistant to drugs currently in clinical standard of care or under study as chemotherapeutic agents in cancer. We hope to discover the nature of proteins whose upregulation mediates resistance to specific drugs, and then continue from there to work on mechanisms and clinical relevance. There are many opportunities to study many drugs in collaboration with local scientists. I have just managed to put together funds for someone to join Sarmishtha De, a postdoctoral fellow already working with me on this project, and would like to recruit an additional fellow fairly soon. I am sending this inquiry locally first, before searching outside Cleveland. Please let me know if you are aware of someone with the skills and interest to participate in this project.

Thanks and best wishes,

George Stark (


**All events are open to anyone interested in attending

February 4

Cancer Genetics/ Biology Journal Club cancelled

Pathology Research Seminar
Warren S. Pear, MD, PhD
Associate Professor, Pathology and Laboratory Medicine
University of Pennsylvania
Topic: Notch Signaling at the Interface of Lymphoid Development and Leukemia
12:00 pm WRB Auditorium

Skeletal Research Center Seminar
Vance E. Holt III
Graduate Student, Biology
Topic: HIF–1: A Possible Molecular Switch for MSC Mobilization
4:00 pm 123 Millis

February 5

Neurosciences Seminar
Stephen M. Maricich, MD, PhD
Assistant Professor, Pediatric Neurology
Baylor College of Medicine
Topic: Atoh-1 Lineal Neurons of the Cochlear Nucleus are Required for Hearing and for the Survival of Central and Peripheral Auditory Pathway Neuronal Populations
10:30 am BRB 105

EECS Seminar
Douglas Lenat
Topic: Computers Versus Common Sense 11:30 am White 411

Regulation of Cell Death- Apoptosis & Autophagy Basic Science Focus Group Meeting
February 5
3:00 pm WRB 3-136

February 6

Grand Rounds
Philip Cola
Vice President, Research and Technology
IRB Administrative Office Head
University Hospitals of Cleveland
Stephen Behm
Director, Technology Management
University Hospitals of Cleveland
Topic: Technology Management at UHCMC
8:00 am Lerner B-151

February 7

Neurosciences Seminar
Richard Miller, PhD
Northwestern University
Topic: Chemokine Signaling in the Developing and Adult Brain
12:10 pm BRB 105

TREC Seminar
Ariel Feldstein, MD
Professor, Medicine- Pediatric Gastroenterology
Cleveland Clinic/CWRU
Topic: TBA
4:00 pm BRB 732

February 8

Hematology/Oncology Fellows
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Center Grand Rounds
Robert Diasio, MD
Professor, Pharmacology
Mayo Clinic College of Medicine
Topic: DPD Deficiency
8:00 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series/ Blood Club
Deborah Schrag, MD
Topic: TBA
12:00 pm BRB 105


For a complete listing of LRI seminars click here.


Physiology & Biophysics Minisymposium
February 11
Keynote Speaker: Dr. Zena Werb, University of California at San Francisco
Topic: Phenotyping Genetically Modified Mice
Minisymposium begins at 1:30 pm; Keynote Speaker to speak at 4:00 pm SOM E301

Systems Biology Basic Science of Cancer Focus Group meeting
February 15
9:00 am Manor House

Prevention and Control Seminar
February 21
Siran Koroukian, PhD
Assistant Professor, Epidemiology & Biostatistics
Topic: Trajectory Care in Elders With Cancer
3:30 pm Wearn 137

Tumor Cell Adhesion, Growth Factor Receptor Signaling, Stromal Interactions, Migration and Metastasis Basic Science Focus Group Mini Retreat
February 26
1:00 pm WRB 2-136


**For more information on these symposiums, please contact Christine Rhoads.

Geriatric Oncology and Primary Care: Promoting Partnerships in Practice and Research
April 3-4
Dively Center
Course Directors: Nathan Berger, MD and Julia Rose, PhD

Update on Cervical Cancer Prevention: New Technology, New Evidence, and New Recommendations
April 18
Ritz Carlton Cleveland
Course Directors: Stephen Waggoner, MD and Kristine Zanotti, MD

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood

FUNDING OPPORTUNITY – Robert Wood Johnson Foundation

The Robert Wood Johnson Foundation (RWJF) has joined in a national effort to advance the science of continuous quality improvement (CQI) research, and is currently seeking proposals that:

*develop methods, tools and standards for the design, conduct and reporting of CQI research and evaluations, including standardized typologies, definitions and measures of key concepts and consensus statements;

*demonstrate how the paradigms, methods and approaches from other disciplines can advance the science of CQI research;

*develop and test new theoretical models, conceptual frameworks and logic models to explain CQI initiatives;

*demonstrate how rapid-cycle "run-chart" or "PDSA-cycle" data can be used to rigorously evaluate the effectiveness of CQI interventions implemented to address key quality challenges; and/or

*develop methods to systematically capture implementation context information.

Proposals that address other issues that will advance the science of CQI research as it applies to health and health care will also be accepted.

An informational applicant conference call will be held on February 6 to provide interested applicants an overview of this solicitation and offer an opportunity to ask questions. To register for this call, click here.

Deadline for proposals: March 14

For more information, please click here.

CALL FOR ABSTRACTS – International Society for Stem Cell Research 6th Annual Meeting

June 11-14
Pennsylvania Convention Center
Philadelphia, PA

The ISSCR Annual Meeting provides an opportunity to hear groundbreaking research from all areas of stem cell science. The meeting is an excellent forum for scientists to present and discuss their latest research, with participants from academic, industry and government setting from around the world.

Submission deadline: February 7 (12:00 pm CST)

For details, please click here.


The International Society for Cellular Therapy (ISCT) will be holding a regional meeting on April 4-5 at the Ohio State University Biomedical Research Tower in Columbus, Ohio. This meeting is targeted towards laboratory practitioners and technicians working in cellular therapy, and anyone interested in networking with cell therapy practitioners at a small, technically focused, reasonably priced meeting.

For more information, click here.


2008 CWRU Presidential Research Initiative (PRI) Grant Program
Deadline: February 4

Landon Foundation–AACR Innovator Award for Cancer Prevention Research
Deadline: February 15

Ohio Cancer Research Associates
Deadline: February 22

Nancy R. Gelman Foundation
Deadline: February 22

2008 NASA Space Radiation Summer School
Deadline: February 28

Robert Wood Johnson Foundation Clinical Scholars Program
Deadline: February 29

Leukemia and Lymphoma Society Translational Research Program
Deadline: March 1

Lady Tata Memorial Trust International Award for Research in Leukemia
Deadline: March 1

Ladies Auxiliary to the Veterans of Foreign Wars (VFW) of the United States
Deadline: March 8

McDonnell Foundation Research Awards
Deadline: March 12

Lance Armstrong Foundation Research Grants
Deadline: March 14

Prostate Cancer Research Foundation 2008 Challenge Awards
Deadline: March 14

Robert Wood Johnson Foundation Harold Amos Medical Faculty Development Program
Deadline: March 19

NIH Shared Instrumentation Grant Program
Deadline: March 24

Lance Armstrong Foundation Community Grants
Deadline: March 24

Cancer Research Institute
Deadline: April 1

NIH Bulletin – Notices and Funding Opportunities

NIH Fiscal Policy for Grant Awards – FY 2008 (NOT-OD-08-036)

Announcing the FY 2008 NIH Director's Bridge Awards (NOT-OD-08-037)

Administrative Supplements to Promote Research Collaborations for Projects Currently Funded by the National Cancer Institute (NCI) Division of Cancer Biology (NOT-CA-08-007)

Revision Awards to Support AIDS-related Malignancies Research Training to Currently Funded AIDS International Training and Research Program Awards (D43) (RFA-TW-08-004)

The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R01)(PA-08-083)

The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R21)(PA-08-084)

The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R03)(PA-08-085)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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