Case Comprehensive Cancer Center Newsletter

December 8, 2008


Please join us in welcoming the following new members of the Case CCC:

Timothy Gilligan, MD
Associate Professor, Molecular Medicine
Associate Staff, Solid Tumor Oncology
GU Malignancies Program

Hui Grace Jin, PhD
Instructor, Pharmacology
Molecular Mechanisms of Oncogenesis Program

Tamila Kindwall-Keller, DO
Assistant Professor, Medicine- Hematology/Oncology
Clinical Program

Timothy Nilsen, PhD
Professor and Director, Center for RNA Molecular Biology
Molecular Mechanisms of Oncogenesis Program

Nora Nock, PhD
Assistant Professor, Epidemiology & Biostatistics
Aging-Cancer Research Program

Brian Ragan, PhD
Assistant Professor, Family Medicine
Cancer Prevention, Control & Population Research Program

Gregory Tochtrop, PhD
Assistant Professor, Chemistry
Developmental Therapeutics Program with a focus on Imaging

Case CCC in the News

Don't Forget the Human Toll of Cancer
The News Herald - Dec 3, 2008 too does work at the Ireland Cancer Center and Case Comprehensive Cancer Center and the Cleveland Clinic's Lerner Research Institute.

Local Smoking-Cessation Groups Fear Budget Cuts Will Snuff Out Progress
The Plain Dealer - Dec 1, 2008
That's an area that also concerns Dr. Afshin Dowlati, director of thoracic oncology at University Hospitals' Ireland Cancer Center...

Sibling Outreach Program at Cleveland Clinic Makes Special Time for Overlooked Children
The Plain Dealer - Dec 1, 2008
...coordinates the program along with Dr. Greg Plautz, chairman of the pediatric hematology-oncology department...

Tumor Surroundings Influence Survival in Diffuse Large-B-cell Lymphoma
MedPage Today, NJ - Nov 26, 2008
... affect a neoplasm, the finding is important because it should affect how cancers are classified, said Charis Eng, MD, PhD, of the Cleveland Clinic...


Director's Update
Advances in Imaging Reveal New and Better Ways to Fight Cancer

Featured Article
Clinic Will Speed Drug Development

Cancer Research Highlights
Tumor Environment Linked to Survival in Lymphoma

After Menopause, Weight Affects Breast Cancer Rates More than Mammography Use

Breast Cancer Family History Boosts Risk, Even without BRCA Mutations

MEMBERSHIP NEWS– Gynecologic Oncology Group (GOG) Committee and Board Appointments

Vivian von Gruenigen, MD was recently appointed to the Gynecologic Oncology Group (GOG) Uterine Corpus Committee, effective January 2009. Also, Steven Waggoner, MD was recently appointed to GOG Board of Directors. Appointment to a GOG committee or board is a significant achievement, and their selection is a reflection on their value to the GOG and the strength of the Division of Gynecologic Oncology.

Congratulations to you both!


In the spirit of the holidays, the Case Comprehensive Cancer Center is sponsoring a family in need from the Ireland Cancer Center. The family consists of Mr. and Mrs. S and two children, a girl age 5 and a boy age 4. The father was recently diagnosed with an unknown primary cancer of the head and neck in September, 2008. We hope you will consider making a donation. The family is in great need of the basics to maintain a household. They do of most of their shopping at Wal-Mart. They also need glasses, plates and silverware (plastic preferably since they have small children). Anything you are able to give is appreciated, such as gift cards, gas cards, and even cash.

Please turn in all donations to Gillian Irwin (Wearn 152) by Monday, December 15. Questions? Call 844-8317, or email

Happy holidays to you and your families!


Produced by the Office of Complementary and Alternative Medicine

United States and China Sign Research Agreement on Traditional Chinese Medicine

A Conversation With
Paige McDonald, PhD, MPH, Program Director and Chief of Basic Biobehavioral Research Branch, Behavioral Research Branch, Division of Cancer Control and Population Sciences

News from the Field
FDA Warns Against Selling and Using Fake Cancer 'Cures'

Funding Opportunities
Quick-Trials for Novel Cancer Therapies and Prevention: Exploratory Grants

Research Resources
NIH Shares Tips about Grants

Research Highlights
Selenium May Augment Finasteride in Preventing Prostate Cancer

Fish Oils May Help Fight Prostate Cancer Progression

FUNDING OPPORTUNITY– AACR Minority Scholar in Cancer Research Awards

AACR Minority Scholar Awards in Cancer Research are offered to eligible minority scientists wishing to participate in Annual Meetings and Special Conferences of the American Association for Cancer Research (AACR). These awards are intended to enhance the education and training of minority researchers and to increase the visibility and recognition of minorities involved in cancer research.

Candidates must be full-time graduate students, medical students, residents, clinical or postdoctoral fellows, or junior faculty members. Only minority groups that have been defined by the National Cancer Institute as being traditionally underrepresented in cancer and biomedical research are eligible for this award: African Americans, Alaskan Natives, Hispanics, Native Americans, and Native Pacific Islanders. Candidates must be citizens or permanent residents of the United States or Canada.

Deadline: December 15

For more information, please click here.

FUNDING OPPORTUNITY– UICC Yamagiwa-Yoshida Memorial International Study Grants

The International Union Against Cancer (UICC) is accepting application for Yamagiwa-Yoshida Memorial International Study Grants. The objectives of these grants are to: to initiate, set up or pursue bilateral cancer research projects with collaborating investigators abroad; to exchange and exploit complementary skills and material; and to to receive training in advanced experimental research methods and techniques.

These awards are open to investigators, clinicians, epidemiologists, public health professionals who have appropriate scientific or medical qualifications and a minimum of two years postdoctoral experience, have active engagement in cancer research, and have recent publications in the international peer-reviewed literature.

Deadline: January 15

For more information, please click here.


**All events are open to anyone interested in attending

December 8

Hematology/Oncology Research In Progress Seminar cancelled

Pathology Research Seminar Series
David Wald, MD, PhD
Instructor, Pathology
Topic: Novel AML Differentiation-Inducing Agents
12:00 pm WRB 1-413

December 9

Cancer Biology Faculty Candidate
Sudha Sharma, PhD
Research Fellow, Pathology
Harvard Medical School
Topic: Molecular Mechanisms of Genomic Instability in Cancer and Aging: Insights from the Analyses of RecQ-like Helicases
11:00 am NC1-202 Cleveland Clinic

Neurosciences Thesis Defense
Katherine Krueger
Student, Neurosciences
Topic: Transcriptional Regulation of FEV, a Human Serotonin Neuron Developmental Control Gene
12:00 pm SOM E609

December 10

Grand Rounds
Shilen Patel, MD
Fellow, Div. of Hem/Onc
Topic: Bladder Carcinoma
8:00 am Lerner Tower B-151

CSCRM Seminar
Yakov Elgudin, MD, PhD
Assistant Professor, Surgery
CWRU/ VA Medical Center
Meghan Smith, PhD
Candidate, Chemical Engineering and Macromolecular Science and Engineering
Topic: Heart Valve Tissue Engineering: Current Status and Development of a Novel Multifunctional Biodegradable Scaffold
4:30 pm NA5-08 Cleveland Clinic

December 11

TREC Seminar cancelled

Taussig Cancer Institute Core Curriculum Series
Anna Koo, MD
Hematologic Oncology and Blood Disorders, Taussig Cancer Institute
Cleveland Clinic
Topic: Therapeutic Apheresis in Hematology and Oncology
12:00 pm R3-002 Cleveland Clinic

Neurosciences Seminar
Kathryn Albers, PhD
Associate Professor, Medicine
University of Pittsburgh
Topic: Growth Factor Modulation of Sensory Neuron Phenotype
12:10 pm SOM E501

December 12

Hematology/ Oncology Fellows Seminar
Ajita Narayan, MD
Fellow, Div. of Hem/Onc
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Harold Freeman, MD
President, Ralph Lauren Center for Cancer Care and Prevention
Topic: Patient Navigation
8:00 am R3/002-003 Cleveland Clinic

Cell Biology Seminar
Dolph Hatfield, PhD
National Cancer Institute
National Institutes of Health
Topic: Biosynthesis of Selenocysteine, the 21st Amino in Eukaryotes, and Its Role in Human Health
10:00 am NC1-202 Cleveland Clinic

Cancer Center Seminar Series/ Blood Club
Kevin Bunting, PhD
Associate Professor, Medicine- Hem/Onc
Topic: Cytokine Signals Modulating Quiescence and Function of Adult Hematopoietic Stem Cells
12:00 pm BRB 105


For a complete listing of LRI seminars click here.



Olof Pearson Lecture
Presented by the Case Comprehensive Cancer Center and the Division of Hematology/ Oncology
December 17 at 4:00 pm, WRB 1-413
Eileen White, PhD, Professor of Molecular Biology and Biochemistry and Associate Director for Basic Science at the Cancer Institute of New Jersey
Topic: Role of Autophagy in Cancer
Please contact Kelly Sliter for more information

Emerging Trends in Cancer Immunotherapy
February 18, 2009
Holiday Inn, Independence
Course Directors: Drs. Henry Koon, Joseph Baar, Andrew Sloan
Details to follow

Family-Centered Care
March 21, 2009
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17, 2009
CWRU campus
For details, click here.

Annual Breast Cancer Update: Highlights of the National Meetings
June 19, 2009
Marriott Cleveland East, Warrensville Heights
Details to follow

Case CCC Scientific Retreat 2009
July 10-11, 2009
Details to follow

**For more information on these symposiums, please contact Christine Rhoads.

FUNDING OPPORTUNITY– Goldhirsh Foundation Brain Tumor Research Awards Program

The Goldhirsh Foundation is interested in providing strategic investment in both pediatric and adult brain tumor research to accelerate progress toward more effective treatment for malignant diffuse glioma tumors. Applications are encouraged from investigators working in the continuum between basic research and clinical application, integrating and translating knowledge in various disciplines into meaningful progress for patients. Examples of funding areas include but are not limited to oncogenomics and proteomics, genetically engineered models, the discovery and testing of small molecule therapies, unusual drug delivery systems, or improved brain imaging techniques. Research projects at the interface of developmental biology and cancer along the stem cell to glial axis are eligible.

Initial Proposal Deadline: January 13
Full Proposal Deadline (invite only): April 21

For details, please click here.

MARK YOUR CALENDARS– Weekly Seminar Series on Applied Biostatistics in Clinical Research

Mark Schluchter, PhD will be teaching a weekly seminar series on Applied Biostatistics in Clinical Research, sponsored by W.T. Dahms Clinical Research Unit and the Cleveland Clinical and Translational Sciences Collaborative (CTSC). The seminars will run Mondays from 4:00 pm - 5:30 pm in School of Medicine E501, January 12– March 9, 2009.

Online registration is open. To register and for more information, click here. For questions about the course, please contact Dr. Schluchter at

FUNDING OPPORTUNITY– James S. McDonnell Foundation

The Foundation offers Collaborative Activity Awards to initiate interdisciplinary discussions on problems or issues, to help launch interdisciplinary research networks, or to fund communities of researchers/practitioners dedicated to developing new methods, tools, and applications of basic research to applied problems.

In each case the focus of the collaborative activity must meet the program guidelines for one of the following program areas:
–Bridging Brain, Mind, and Behavior
–Studying Complex Systems
–Brain Cancer Research

Applications are continuously accepted for these awards.

For more information, please click here.

MARK YOUR CALENDARS– Molecular Targets for Cancer Prevention Symposium

February 4-5, 2009
NIH Natcher Conference Center
Bethesda, Maryland

The Center for Cancer Research and the Division of Cancer Prevention at the National Cancer Institute are presenting Molecular Targets for Cancer Prevention Symposium on February 4-5, 2009 at the NIH Natcher Conference Center in Bethesda, Maryland. Evidence from both preclinical and clinical studies will provide an exciting forum for timely discussion and debate on the state-of-the-science, recent advances, and opportunities for discovery.

Registration Deadline: January 11, 2009

For more information, please click here.

CALL FOR PAPERS– Ohio Collaborative Conference on Bioinformatics (OCCBIO)

The 4th Annual Ohio Collaborative Conference on Bioinformatics (OCCBIO 2009) will be held at CWRU June 15-17, 2009. The conference provides an interdisciplinary forum for the discussion of methods, research findings, and experiences in the area of Bioinformatics and Computational Biology. An important goal of the conference is to foster long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology that benefit Ohio.

OCCBIO invites researchers in the broad area of bioinformatics to submit their unpublished work to the conference. The conference proceedings will be indexed.

Papers will be accepted December 27, 2008- January 27, 2009

For details, please click here.

MARK YOUR CALENDARS–2nd Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science

March 16–18, 2009
Bethesda North Marriott Hotel & Conference Center
Bethesda, MD

Human biospecimens are the foundation of the translational research that will transform patient care. The 2009 BRN Symposium: Advancing Cancer Research Through Biospecimen Science will focus on the significant impact of pre-analytical biospecimen variables on cancer research and molecular medicine. This promises to be a stimulating and informative three-day event that will feature interactive discussions and presentations about biospecimen quality and recent advances in biospecimen science.

Abstract Submission Deadline: February 9, 2009
Registration Deadline: February 17, 2009

For more information, please click here.


AACR Anna D. Barker Fellowship in Basic Cancer Research
Deadline: December 10

AACR-Astellas USA Foundation Fellowships in Basic Cancer Research
Deadline: December 10

AACR-Astellas USA Foundation Fellowship in Clinical/Translational Cancer Research
Deadline: December 10

AACR-Bristol-Myers Squibb Oncology Fellowship in Clinical Cancer Research
Deadline: December 10

AACR-AstraZeneca Fellowship for Translational Lung Cancer Research
Deadline: December 10

AACR Minority-Serving Institution Faculty Scholar in Cancer Research Awards
Deadline: December 10

AACR Anna D. Barker Fellowship in Basic Cancer Research
Deadline: December 10

AACR-Astellas USA Foundation Fellowships in Basic Cancer Research
Deadline: December 10

ACS MEN2 Thyroid Cancer Professorship
Deadline: December 15

Sallie Rosen Kaplan Fellowship
Deadline: December 15

NIH Director's Pioneer Awards
Deadline: December 17

AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research
Deadline: December 18

AACR-Colorectal Cancer Coalition Fellows Grant, in memory of Lisa Dubow
Deadline: December 18

ASCO Advanced Clinical Research Awards
Deadline: January 8

Skin Diseases Research Center
Deadline: January 9

Ovarian Cancer Research Program (OCRP)
Pre-Application Deadline: January 13
Application Deadline: January 27

AACR Career Development Awards for Pediatric Cancer Research
Deadline: January 13

ASCO Cancer Foundation IDEA Grants
Deadline: January 14

NIH Director's New Innovator Awards
Deadline: January 15

Komen/ ASCO Loan Repayment Program
Deadline: January 15

ASCO Cancer Foundation Translational Research Professorship
Deadline: January 22

Ovarian Cancer Research Program (OCRP)
Application Deadline: January 27

Pfizer Oncology Clinical Fellowship Awards
Deadline: January 31

Pfizer Fellowship In Health Disparities
Deadline: January 31

Pfizer Visiting Professorships in Oncology
Deadline: January 31

NCI Short-Term Scientist Exchange Program
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Enhancing Peer Review: The NIH Announces Updated Implementation Timeline (NOT-OD-09-023)

Enhancing Peer Review: The NIH Announces New Scoring Procedures for Evaluation of Research Applications Received for Potential FY2010 Funding (NOT-OD-09-024)

Enhancing Peer Review: The NIH Announces Enhanced Review Criteria for Evaluation of Research Applications Received for Potential FY2010 Funding (NOT-OD-09-025)

NIH Announces the Availability of Adobe-Based Grant Application Forms (NOT-OD-09-026)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax


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