Case Comprehensive Cancer Center Newsletter

December 15, 2008

Case CCC in the News

Most Triple-negative Breast Cancers Express Muc-1 Target
Science Daily (press release) - Dec 12, 2008
Joseph Baar, MD, PhD, Director of Breast Cancer Research at the Ireland Cancer Center, and colleagues analyzed 53 tumors and determined that 92 percent of ...

Studies: Vitamins, selenium won't prevent prostate cancer
CNN - Dec 9, 2008
... MD, of the University of Texas MD Anderson Cancer Center, and Eric A. Klein, MD, of the Cleveland Clinic Lerner College of Medicine; and the Physicians' ...

MARK YOUR CALENDARS– Cancer Center Scientific Series

The Case CCC is pleased to announce the Cancer Center Scientific Series, the first installment of which is scheduled for Thursday, January 8, 2009 from 4:00 pm - 6:00 pm in the Wolstein Research Building Auditorium, and will feature reports from the following Cancer Center Imaging Pilot Project awardees:

Susann Brady-Kalnay, PhD
Imaging Glioblastomas Using Probes that Detect the Receptor Protein Tyrosine Phosphatase mu

Chris Flask, PhD
Development of PARACEST-MRI Imaging Agents for in vivo Assessment of Autophagy

Yanming Wang, PhD
In vivo Quantification of DNA Damages in Cancer Chemotherapies

Reception to follow. Everyone is welcome to attend.

MARK YOUR CALENDARS– Case CCC Basic Science Faculty Candidate Seminar

Case CCC Basic Science Faculty Candidate Hongwu Zheng, PhD will be giving a seminar on Monday, January 12, 2009 at 4:00 pm in Wolstein Research Building 1402. Dr. Zheng, a Post-Doc Research Fellow at the Dana Farber Cancer Institute/ Harvard Medical School, will be presenting Understanding Glioma Pathogenesis. All are encouraged to attend.

FUNDING OPPORTUNITY– Goldhirsh Foundation Brain Tumor Research Awards Program

The Goldhirsh Foundation is interested in providing strategic investment in both pediatric and adult brain tumor research to accelerate progress toward more effective treatment for malignant diffuse glioma tumors. Applications are encouraged from investigators working in the continuum between basic research and clinical application, integrating and translating knowledge in various disciplines into meaningful progress for patients. Examples of funding areas include but are not limited to oncogenomics and proteomics, genetically engineered models, the discovery and testing of small molecule therapies, unusual drug delivery systems, or improved brain imaging techniques. Research projects at the interface of developmental biology and cancer along the stem cell to glial axis are eligible.

Initial Proposal Deadline: January 13
Full Proposal Deadline (invite only): April 21

For details, please click here.


In the spirit of the holidays, the Case Comprehensive Cancer Center is sponsoring a family in need from the Ireland Cancer Center. The family consists of Mr. and Mrs. S and two children, a girl age 5 and a boy age 4. The father was recently diagnosed with an unknown primary cancer of the head and neck in September, 2008. We hope you will consider making a donation. The family is in great need of the basics to maintain a household. They do of most of their shopping at Wal-Mart. They also need glasses, plates and silverware (plastic preferably since they have small children). Anything you are able to give is appreciated, such as gift cards, gas cards, and even cash.

The deadline for donations has been extended to Wednesday, December 17. Please turn in all donations to Gillian Irwin (Wearn 152). Questions? Call 844-8317, or email

Thanks to everyone who already donated; your generosity is greatly appreciated!

Happy holidays to you and your families!


The AACR is pleased to announce a call for Letters of Intent for Stand Up To Cancer (SU2C) Innovative Research Grants. These grants, established in honor of the late Judah Folkman, MD, are open to independent investigators early in their careers and will fund novel, high-risk, high-reward cancer research proposals that have significant potential for translational application and hold great promise for advancing SU2C's overarching goal of improving and saving the lives of patients.

Applicants must be tenure-track, independent investigators, who have completed their training no more than 7 years prior to the start of the grant term. That is, the applicant's first independent position must have started on or after August 2, 2002. Postdoctoral fellows, clinical research fellows, or any other researchers-in-training who are working under the direction of a scientific mentor are not eligible to apply. Proposals may focus on any discipline within basic, translational, or clinical research, provided that these criteria are met.

LOI Deadline: January 22, 2009 Application Deadline (invite only): May 15, 2009

For more information, please click here

CALL FOR PAPERS– Ohio Collaborative Conference on Bioinformatics (OCCBIO)

The 4th Annual Ohio Collaborative Conference on Bioinformatics (OCCBIO 2009) will be held at CWRU June 15-17, 2009. The conference provides an interdisciplinary forum for the discussion of methods, research findings, and experiences in the area of Bioinformatics and Computational Biology. An important goal of the conference is to foster long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology that benefit Ohio.

OCCBIO invites researchers in the broad area of bioinformatics to submit their unpublished work to the conference. The conference proceedings will be indexed.

Papers will be accepted December 27, 2008- January 27, 2009

For details, please click here.

MARK YOUR CALENDARS– Weekly Seminar Series on Applied Biostatistics in Clinical Research

Mark Schluchter, PhD will be teaching a weekly seminar series on Applied Biostatistics in Clinical Research, sponsored by W.T. Dahms Clinical Research Unit and the Cleveland Clinical and Translational Sciences Collaborative (CTSC). The seminars will run Mondays from 4:00 pm - 5:30 pm in School of Medicine E501, January 12– March 9, 2009.

Online registration is open. To register and for more information, click here. For questions about the course, please contact Dr. Schluchter at


**All events are open to anyone interested in attending

December 15

Hematology/Oncology Research In Progress Seminar
Jeffrey Kolthammer
Student, McCrae Lab, Div. of Hem/Onc
Topic: Toward Quantitative in-vivo Imaging of Stem Cell Behavior
12:00 pm WRB 2-136

Pathology Research Seminar Series
Sanjay Pimplikar, PhD
Assistant Staff, Neurosciences
Cleveland Clinic
Topic: The Role of APP Intracellular Domain in AD Pathogenesis (or, So long, Amyloid, we hardly knew ye)
12:00 pm WRB 1-413 (Auditorium)

December 16

Cancer Biology Faculty Candidate
Mushui Dai, MD, PhD
Assistant Research Professor, Biochemistry & Molecular Biology
Indiana University School of Medicine
Topic: A Dual Role for Ribosomal Proteins in Cell Cycle Control: Activation of p53 and Inhibition of c-Myc
11:00 am NC1-202 Cleveland Clinic

Taussig Cancer Institute Core Curriculum Series
Brian Rini, MD
Associate Professor, Molecular Medicine
Associate Staff, Solid Tumor Oncology
CWRU/ Cleveland Clinic
Topic: Renal Cell Cancer
12:00 pm R3-002 Cleveland Clinic

Cancer Center Special Seminar
Carlos Croce, MD
Professor and Chair, Molecular Virology, Immunology & Medical Genetics
Ohio State University
Topic: Role of microRNAs in Human Cancer
12:00 pm SOM W331

December 17

Neurosurgery Grand Rounds
Clifford Robinson, MD
Resident, Radiation Oncology
Cleveland Clinic
Topic: DNA Repair in Malignant Glioma
7:30 am TT1-100 Cleveland Clinic

Grand Rounds
Matthew Cooney, MD
Assistant Professor, Div. of Hem/Onc
Topic: Novel Phase I Combination Trials of Anti-Angiogenic Agents
8:00 am Lerner Tower B-151

Olof Pearson Lecture
Presented by the Case Comprehensive Cancer Center and the Division of Hematology/ Oncology
Eileen White, PhD
Professor, Molecular Biology and Biochemistry
Associate Director, Basic Science
Cancer Institute of New Jersey
Topic: Role of Apoptosis and Autophagy in Cancer Progression and Therapy
4:00 pm WRB 1-413 (Auditorium)

Developmental Therapeutics Meeting
5:00 pm WRB 2-136

December 18

Aging-Cancer-TREC Seminars cancelled; series will resume January 2009

Taussig Cancer Institute Core Curriculum Series
Timothy Gilligan, MD
Associate Professor, Molecular Medicine
Associate Staff, Solid Tumor Oncology
CWRU/ Cleveland Clinic
Topic: Overview of Bladder Cancer
12:00 pm R3-002 Cleveland Clinic

December 19

Cancer Center Seminar Series/ Blood Club cancelled

Taussig Cancer Institute Grand Rounds cancelled; series will resume January 2009

Hematology/ Oncology Fellows Seminar
Shilen Patel, MD
Fellow, Div. of Hem/Onc
Topic: TBA
8:00 am Wearn 137


For a complete listing of LRI seminars click here.



Emerging Trends in Cancer Immunotherapy
February 18, 2009
Holiday Inn, Independence
Course Directors: Drs. Henry Koon, Joseph Baar, Andrew Sloan
Details to follow

Family-Centered Care
March 21, 2009
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17, 2009
CWRU campus
For details, click here.

Annual Breast Cancer Update: Highlights of the National Meetings
June 19, 2009
Marriott Cleveland East, Warrensville Heights
Details to follow

Case CCC Scientific Retreat 2009
July 10-11, 2009
Details to follow

**For more information on these symposiums, please contact Christine Rhoads.

FUNDING OPPORTUNITY– James S. McDonnell Foundation

The Foundation offers Collaborative Activity Awards to initiate interdisciplinary discussions on problems or issues, to help launch interdisciplinary research networks, or to fund communities of researchers/practitioners dedicated to developing new methods, tools, and applications of basic research to applied problems.

In each case the focus of the collaborative activity must meet the program guidelines for one of the following program areas:
–Bridging Brain, Mind, and Behavior
–Studying Complex Systems
–Brain Cancer Research

Applications are continuously accepted for these awards.

For more information, please click here.

MARK YOUR CALENDARS– Molecular Targets for Cancer Prevention Symposium

February 4-5, 2009
NIH Natcher Conference Center
Bethesda, Maryland

The Center for Cancer Research and the Division of Cancer Prevention at the National Cancer Institute are presenting Molecular Targets for Cancer Prevention Symposium on February 4-5, 2009 at the NIH Natcher Conference Center in Bethesda, Maryland. Evidence from both preclinical and clinical studies will provide an exciting forum for timely discussion and debate on the state-of-the-science, recent advances, and opportunities for discovery.

Registration Deadline: January 11, 2009

For more information, please click here.

MARK YOUR CALENDARS–2nd Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science

March 16–18, 2009
Bethesda North Marriott Hotel & Conference Center
Bethesda, MD

Human biospecimens are the foundation of the translational research that will transform patient care. The 2009 BRN Symposium: Advancing Cancer Research Through Biospecimen Science will focus on the significant impact of pre-analytical biospecimen variables on cancer research and molecular medicine. This promises to be a stimulating and informative three-day event that will feature interactive discussions and presentations about biospecimen quality and recent advances in biospecimen science.

Abstract Submission Deadline: February 9, 2009
Registration Deadline: February 17, 2009

For more information, please click here.


AACR Minority Scholar in Cancer Research Awards
Deadline: December 15

ACS MEN2 Thyroid Cancer Professorship
Deadline: December 15

Sallie Rosen Kaplan Fellowship
Deadline: December 15

NIH Director's Pioneer Awards
Deadline: December 17

AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research
Deadline: December 18

AACR-Colorectal Cancer Coalition Fellows Grant, in memory of Lisa Dubow
Deadline: December 18

ASCO Advanced Clinical Research Awards
Deadline: January 8

Skin Diseases Research Center
Deadline: January 9

Ovarian Cancer Research Program (OCRP)
Pre-Application Deadline: January 13
Application Deadline: January 27

AACR Career Development Awards for Pediatric Cancer Research
Deadline: January 13

ASCO Cancer Foundation IDEA Grants
Deadline: January 14

UICC Yamagiwa-Yoshida Memorial International Study Grants
Deadline: January 15

NIH Director's New Innovator Awards
Deadline: January 15

Komen/ ASCO Loan Repayment Program
Deadline: January 15

ASCO Cancer Foundation Translational Research Professorship
Deadline: January 22

Ovarian Cancer Research Program (OCRP)
Application Deadline: January 27

Pfizer Oncology Clinical Fellowship Awards
Deadline: January 31

Pfizer Fellowship In Health Disparities
Deadline: January 31

Pfizer Visiting Professorships in Oncology
Deadline: January 31

NCI Short-Term Scientist Exchange Program
Deadline: Open

NIH Bulletin – Notices and Funding Opportunities

Mentored Patient-Oriented Research Career Development Award (K23) (PA-09-043)

Mentored Clinical Scientist Research Career Development Award (K08) (PA-09-042)

Mentored Research Scientist Development Award (K01) (PA-09-040)

Mentored Quantitative Research Development Award (K25) (PA-09-039)

NIH Pathway to Independence Award (K99/R00) (PA-09-036)

Physical Science-Oncology Centers (U54) (RFA-CA-09-009) National Cancer Institute

Pre-Application Meeting for RFA-CA-09-009 Physical Science-Oncology Centers (U54) (NOT-CA-09-010)

Immunoregulation of Gastrointestinal Carcinogenesis (R21)(PA-06-290)

Improving Diet and Physical Activity Assessment (R01) (PAR-07-259)

Quick-Trials for Novel Cancer Therapies and Prevention: Exploratory Grants (R21) (PAR-08-025)

Diet, Epigenetic Events, and Cancer Prevention (R01) (PA-07-175)

Memory T Lymphocytes in Cancer Immunology (R21) (PA-06-349)

Memory T Lymphocytes in Cancer Immunology (R01) (PA-07-255)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax


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