Case Comprehensive Cancer Center Newsletter

November 10, 2008

MESSAGE FROM THE DIRECTOR–Appointment of John Sweetenham, MD as Director for Clinical Trials, Case Comprehensive Cancer Center

Please welcome John Sweetenham, MD, Professor of Medicine, Cleveland Clinic Lerner College of Medicine, to the position of Director for Clinical Trials, Case Comprehensive Cancer Center.

I have established this position after consultation with the Senior Leaders of the Cancer Center. The new position of Director for Clinical Trials reflects the need for coordination and oversight of clinical trials across institutions and throughout the regional networks of the affiliated clinical sites of the Case Comprehensive Cancer Center. John will provide this specific service to the Center through his position as Deputy Associate Director for Clinical Research and Staff Investigator, a formal position in the Core Grant for individuals who provide a special coordinating activity to the Center. John comes with considerable experience managing clinical trials at cancer centers and has the title of Associate Director for Clinical Research at Cleveland Clinic.

John will oversee and coordinate many components of the Case Comprehensive Cancer Center clinical trials operations. These include the Case CCC Clinical Trials Unit (Smitha Krishnamurthi, MD, Director) and the Regulatory Office for Clinical Trials for the Case CCC affiliates. He will chair the Cancer Center's Redbook Committee, which establishes the policy and procedures for the conduct of clinical trials and manages clinical trials issues as they arise throughout the Cancer Center. The Committee brings together the Clinical Trials and Regulatory Units as well as the leadership of the Data Safety and Monitoring Committee (Brenda Cooper, MD, Chair) and the Protocol Review and Monitoring Committee (Joanna Brell, MD, Chair and David Adelstein, MD, Co-chair). John's focus will be the coordination of clinical trials activities across the Case CCC, and establishing and maintaining links to the main hospital cancer center clinical trials operations where John serves as Deputy Associate Director for Clinical Research for Taussig Cancer Institute, and Afshin Dowlati, MD serves as Deputy Associate Director for Clinical Research for the Ireland Cancer Center.

John will report to me until the position of Associate Director for Clinical Research at the Case Comprehensive Cancer Center is filled. He will participate in the regular meetings of the Associate Directors for Shared Resources that includes oversight of cores, biostatistics, clinical trials and informatics.

Stan Gerson, MD
Director, Case CCC


EBEN ALSBERG, PHD NAMED ELLISON MEDICAL FOUNDATION NEW SCHOLAR IN AGING

Congratulations to Eben Alsberg, PhD, who was recently named a 2008 Ellison Medical Foundation New Scholar in Aging by the Ellison Medical Foundation. Alsberg was one of 25 people nationally to receive this honor this year. For more information, please click here.


SUSAN G. KOMEN FOR THE CURE AND ASCO PAIR FOR DIVERSITY IN ONCOLOGY INITIATIVE

The American Society of Clinical Oncology (ASCO) and Susan G. Komen for the Cure have teamed up to create a Diversity in Oncology initiative, designed to facilitate the recruitment and retention of individuals from populations underrepresented in medicine to cancer careers, with particular attention to the development of clinical practitioners and investigators. Derek Raghavan, MD, Director of the Taussig Cancer Center, and Otis Brawley, MD currently serve as Co-Chairs of the ASCO Health Disparities Advisory Group.

Three programs have been formed under this initiative:

Komen/ ASCO Loan Repayment Program
This program provides repayment of qualifying educational debt to oncologists, or to oncology fellows upon completion of training, who commit to practicing oncology in a medically underserved region of the United States. This program will repay up to $35,000 per year for two years (up to $70,000 total) of qualifying education loans.

Deadline: January 15, 2009

Komen/ ASCO Medical Student Rotation
This program provides 8-10 week clinical or clinical research oncology rotations for US medical students who are from populations currently underrepresented in medicine. A mentoring component is included, whereby award recipients are paired with a clinical oncologist who will provide ongoing academic and career guidance. Recipients receive a $5,000 stipend for the rotation plus $1,500 for future travel to the ASCO Annual Meeting. An additional $2,000 will be provided to the student's mentor.

Application process will open in December 2008.

Komen/ ASCO Resident Travel Award
This award provides financial support to residents enrolled in an ACGME-accredited Internal Medicine residency program to participate in ASCO's Annual Meeting. To be eligible, individuals must be from a population currently underrepresented in medicine, as defined by the program criteria. A mentoring component is included, whereby award recipients are paired with a clinical oncologist prior to the meeting. The Resident Travel Award includes a $1,500 travel advance, complimentary Annual Meeting registration, and access to the Annual Meeting housing block and ASCO's travel agent.

Application process will open in December 2008.


NCI CANCER BULLETIN

Featured Article
Selenium and Vitamin E Fail to Reduce Prostate Cancer Risk
**Please note: this article contains quotes from Dr. Eric Klein, Taussig Cancer Center, Cleveland Clinic, who is co-Chair on the SELECT trial.

Cancer Research Highlights
Additional Genes Tied to Lung Cancer

Bevacizumab Tested as Imaging Agent

Stress, Depression Linked to Changes in Ovarian Tumors

Guest Update by Dr. Anna Barker
Oncology and the Physical Sciences Converge

EVENTS

**All events are open to anyone interested in attending

November 10

Hematology/Oncology Research In Progress Seminar cancelled

Pathology Research Seminar Series
Riqiang Yan, PhD
Associate Staff, Neurosciences
Cleveland Clinic
Topic: BACE1 and Its Regulator Nogo/RTN Proteins in AD Pathogenesis
12:00 pm WRB 1-413


November 11


November 12

Grand Rounds
Shanmuga Subbiah, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: Triple Negative Breast Cancer
8:00 am Lerner B-151

CSCRM Seminar
Robert Murphy, PhD
Professor, Computational Biology and
Biological Sciences, Biomedical Engineering and Machine Learning
Carnegie Mellon University
Topic: Automated Proteome-Wide Determination and Modeling of Subcellular Location for Systems Biology
4:30 pm WRB 1413


November 13

Physiology & Biophysics Seminar
Qi Zhang, PhD
Postdoctoral Fellow, Molecular and Cellular Physiology
Stanford University
Topic: Using Quantum Dots to Probe Unitary Vesicle Fusion and Recycling
4:00 pm SOM E501

TREC Seminar
Topic: TBA
4:00 pm BRB 732

Practice-Based Research Network Seminar
Topic: Funding for PBRN Research
6:00 pm Cuyahoga County Coroner's Office
RSVP to pbrn@case.edu


November 14

Cancer Center Seminar Series/ Blood Club cancelled

Hematology/ Oncology Fellows
Bindu Gaddipati, MD
Fellow, Div. of Hem/Onc
CWRU/ UH
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Institute Grand Rounds
Eric Small, MD
Professor, Medicine and Urology
University of California, San Francisco
Topic: Castration Resistant or Hormone Resistant Prostate Cancer: What's in a Name?
8:00 am R3/002-003 Cleveland Clinic

more

For a complete listing of LRI seminars click here.


MARK YOUR CALENDARS:

UPCOMING CANCER CENTER SYMPOSIUMS

**For more information on these symposiums, please contact Christine Rhoads.

Family-Centered Care
March 21, 2009
Holiday Inn, Independence
Details to follow

Head and Neck Conference
April 17, 2009
Holiday Inn, Independence
Details to follow

Ohio Collaborative Conference on Bioinformatics (OCCBIO)
June 15 - 17, 2009
CWRU campus
For details, click here.

Annual Breast Cancer Update: Highlights of the National Meetings
June 19, 2009
Marriott Cleveland East, Warrensville Heights
Details to follow

Case CCC Scientific Retreat 2009
July 10-11, 2009
Sawmill Creek Resort in Huron, Ohio
Details to follow



FUNDING OPPORTUNITY– NIH 2009 Director's Pioneer and New Innovator Awards

NIH recently released the RFA for the 2009 Director's Pioneer and New Innovator Awards. Both programs are part of the NIH Roadmap for Medical Research and support exceptionally creative scientists who take highly innovative, potentially high-impact approaches to major challenges in biomedical or behavioral research. NIH expects to make 5-10 Pioneer Awards and up to 24 New Innovator Awards in September 2009. Women and members of groups that are underrepresented in NIH research are encouraged to apply.

Pioneer Awards
Pioneer Awards provide up to $2.5 million in direct costs over 5 years and are open to scientists at any career stage. Proposals accepted November 17- December 17. For details, please click here.

New Innovator Awards
New Innovator Awards provide up to $1.5 million in direct costs over the same period and are for early career investigators who have not received an NIH regular research (R01) or similar NIH grant. Proposals accepted December 15- January 15, 2009. For more information, please click here.


NIH LOAN REPAYMENT PROGRAMS

The NIH Loan Repayment Programs (LRPs) allow scientific investigators to remain in the research workforce, achieve research independence, and focus their efforts on advancing the health of the nation without regard to student loan debt. Each year, some 1,600 research scientists benefit from the more than $70 million NIH invests in their careers through the LRPs. The extramural LRPs include Clinical Research, Pediatric Research, Health Disparities Research, Contraception and Infertility Research, and Clinical Research for Individuals from Disadvantaged Backgrounds.

New LRP contracts are awarded for a two-year period and repay up to $35,000 of qualified educational debt annually. Participants may apply for competitive renewals, which are issued for one or two years. Undergraduate, graduate, medical school and other health professional school loans qualify for repayment. An NIH grant or other NIH funding is not required to apply for or participate in the LRPs.

Applicants must possess a doctoral-level degree (except for the Contraception and Infertility Research LRP); be a U.S. citizen, national, or permanent resident; devote 20 hours or more per week to conducting qualified research funded by a university, domestic nonprofit organization, or federal, state, or local government entity; and have qualified educational loan debt equal to or exceeding 20 percent of their institutional base salary (New applicants only).

Deadline: December 3

For more information, please click here.


FUNDING OPPORTUNITY– American Cancer Society (ACS) Audrey Meyer Mars International Fellowships in Clinical Oncology

The purpose of the Fellowships is to provide one year of advanced training in clinical oncology at participating cancer centers in the United States to qualified physicians and dentists from other countries, particularly countries where advanced training is not readily available. Applications for training in basic cancer research will not be accepted for the award.

Institutions, not prospective trainees, must submit applications for the American Cancer Society (ACS) Audrey Meyer Mars International Fellowships in Clinical Oncology. If you have someone you would like to nominate for this opportunity, please contact gillian.irwin@case.edu.

Internal Deadline: November 14
External Deadline: December 1

For eligibility and other information, please click here.


FUNDING OPPORTUNITY– Friends for an Earlier Breast Cancer Test

Friends for an Earlier Breast Cancer Test, a non-profit organization dedicated to promoting awareness and education and to raising funds for research into earlier detection of breast cancer, is accepting applications for Medical Research Grants. They are interested in pilot projects that focus on new methods to improve detection of early breast cancer, and are especially interested in the development of new techniques in the areas of biological or immunologic methods of early detection.

It is hoped that pilot projects will provide preliminary data that lead to applications for more substantial peer-reviewed funding. Applications are accepted from both established investigators who have funding but want to embark on a new area, as well as those less experienced. In either case, the proposal should represent a new approach to the area of interest. Funds will not be given to enhance ongoing research unless it is clear that a new line of inquiry is being explored. Both domestic and international research proposals are welcome.

Deadline: December 1

For more information, please click here.



PREVIOUSLY ANNOUNCED FUNDING OPPORTUNITIES

Pancreatic Cancer Action Network-AACR Pilot Grants
Deadline: November 10

Pancreatic Cancer Action Network-AACR Career Development Award
Deadline: November 10

Pancreatic Cancer Action Network-AACR Research Fellowship
Deadline: November 10

Charlotte Geyer Foundation
Deadline: November 15

Breast Cancer Research Program Postdoctoral Award
Pre-App Deadline: November 19
Proposal Deadline: December 3

Breast Cancer Research Program Concept Award
Application Deadline: November 20

Landon Foundation-AACR Innovator Award for Cancer Prevention Research
Deadline: November 20

ASCO Cancer Foundation Translational Research Professorship
Letter of Intent Deadline: November 20
External Deadline: January 22, 2009

Susan G. Komen for the Cure Postdoctoral Fellowships
Full Application Deadline: November 20

Landon Foundation-AACR Innovator Award for International Collaboration
Deadline November 20

Prostate Cancer Foundation Creativity Awards
Deadline: November 21

International Union Against Cancer (UICC)
Deadline: December 1

AACR-GlaxoSmithKline Outstanding Clinical Scholars
Deadline: December 1

Breast Cancer Research Program Postdoctoral Award
Proposal Deadline: December 3

Kimmel Scholar Award
Deadline: December 3

Kimmel Translational Science Award
Deadline: December 3

ASCO Advanced Clinical Research Awards
Letter of Intent Deadline: December 4

Susan G. Komen Promise Grants
Full Application Deadline: December 4

AACR Minority-Serving Institution Faculty Scholar in Cancer Research Awards
Deadline: December 10

ACS MEN2 Thyroid Cancer Professorship
Deadline: December 15

Sallie Rosen Kaplan Fellowship
Deadline: December 15

ASCO Advanced Clinical Research Awards
Application Deadline: January 8

ASCO Cancer Foundation Translational Research Professorship
Deadline: January 22

Pfizer Oncology Clinical Fellowship Awards
Deadline: January 31

Pfizer Fellowship In Health Disparities
Deadline: January 31

Pfizer Visiting Professorships in Oncology
Deadline: January 31

NCI Short-Term Scientist Exchange Program
Deadline: Open


NIH Bulletin – Notices and Funding Opportunities

Erythropoiesis Stimulating Agents and Tumor Progression (R01) (PA-09-023)

Erythropoiesis Stimulating Agents and Tumor Progression (R21) (PA-09-024)

Roadmap Transformative R01 Program (R01) (RFA-RM-08-029)

Pre-Application for the 2009 NIH Director's Pioneer Award Program (X02)(PAR-09-012)

Pre-Application for the 2009 NIH Director's New Innovator Award Program (X02) (PAR-09-013)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax
gillian.irwin@case.edu

Janice Hassinger
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
janice.hassinger@uhhospitals.org

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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