Case Comprehensive Cancer Center Newsletter

January 14, 2008


The NIH/ Fogarty International Clinical Research Scholars (FICRS) Support Center at Vanderbilt University Association of American Medical Colleges (AAMC) is pleased to announce a new one-year clinical research training program for US citizens or permanent residents in either post-residency clinical fellowships or in other health-related post-doctoral programs. This new program is sponsored by the Fogarty International Center and several collaborating institutes and centers at the National Institutes of Health and managed by Vanderbilt University, with fiscal support from the Office of AIDS Research, National Cancer Institute, and the National Heart, Lung, and Blood Institute.

The ICRF Program supports one year of mentored clinical research in a developing country setting. Definitions of developing countries are those designated by the World Bank as low income, lower middle, or upper middle income.

Applicants for the fellowship must develop a collaborative research proposal with an eligible institution oversees. The proposed research must be clinical research related to oncology, including radiation therapy, physiology, and other cancer-related issues.

Funding is available in July 2008-June 2009 for four US fellows.

Application forms are currently available and applications are accepted electronically on a rolling basis until April 30, 2008.

For details, please contact Cat Lem, Program Coordinator at or by phone at 615-343-3555.

FUNDING OPPORTUNITY –Burroughs Wellcome Fund

The Burroughs Wellcome Fund is currently accepting applications for their Institutional Award Program Unifying Population and Laboratory Based Sciences.

The awards will provide $500,000 a year for five years in order to stimulate institutional training programs that partner researchers working in schools of medicine and schools (or academic division) of public health. It is anticipated that up to four awards will be made in 2008.

LOI Deadline: March 3

For more information, please click here.

REQUEST FOR PROPOSALS – Samuel Waxman Cancer Research Foundation

The Case Comprehensive Cancer Center has been invited to submit one application for an Individual Grant from the Samuel Waxman Cancer Research Foundation's Institute Without Walls 2008 grant cycle.

Eligibility is restricted to established investigators with a tenure track appointment holding. They must have principal investigator status on at least one grant from a major funding source such as NIH, NSF, DOD, ACS.

Interested and eligible investigators should submit a one-page proposal (with budget) and a biosketch in NIH four-page format with current research activities to the Cancer Center as a Word document via email to:

Proposal Deadline: Friday, February 1

Senior Leadership will select the proposal to be submitted to the Waxman Foundation. External application deadline is April 1.

For more information, click here.

FUNDING OPPORTUNITY – NIH Shared Instrumentation Grant

The NCRR Shared Instrument Grant (SIG) program is soliciting applications from groups of NIH-supported investigators to purchase or upgrade commercially available instruments that cost at least $100,000. The maximum award is $500,000. Types of instruments supported include confocal and electron microscopes, biomedical imagers, mass spectrometers, DNA sequencers, biosensors, cell sorters, X-ray diffraction systems, and NMR spectrometers among others. This funding opportunity will use the NIH S10 mechanism.

Eligible principal investigators include any technically qualified research scientists. Multiple PDs/PIs are not permitted. To be eligible to apply, three or more NIH funded investigators (Principal Investigators of active P01, R01, U01, R35, R37, DP1 or DP2 research grants) who will be users of the requested instruments must be identified. There is no limit to the number of applications an institution may submit, as long as each application is for different types of equipment.

Applications accepted February 24-March 24.

To view the complete notice click here.


The Center for Cancer Research (CCR) announces a new training opportunity for physicians interested in dedicating their careers to clinical oncology research.

Potential areas of interest include: medical oncology, pediatric hematology/oncology, radiation oncology, surgical oncology, surgical pathologies or related specialties.

Deadline: January 15

For more information, please click here.


Feature Article
Gene Variant May Identify Cirrhosis Patients at High Risk of Liver Cancer

Cancer Research Highlights
Sunitinib Linked to Heart Failure and Hypertension

Cancer Doctors May Need Training on Empathy Skills

Biomarkers Linked to DCIS Outcomes

Older Breast Cancer Survivors Less Likely to Adhere to Follow-Up

Trial Shows Some Benefit of Adjuvant Chemo for Early Colorectal Cancer

Director's Update
Coding Cancer Research Accurately

FUNDING OPPORTUNITY – Multiple Myeloma Research Foundation

The Multiple Myeloma Research Foundation (MMRF) is currently accepting applications for the following research grant awards:

  • Fellow's Awards
    Provide funding to researchers with less than five years experience (post graduate degree) and working under the supervision of a research sponsor. Proposals may request to $75,000 for one year. Deadline: March 1

  • Senior Research Awards
    Provide funding to investigators who have been working in blood cancer research for a minimum of five years. Proposals may request up to $100,000 per year for two years. Deadline: February 1

  • Validation of Novel Combinations and Novel Compounds
    Novel combination therapies and the sequencing of these therapies hold tremendous promise in treating multiple myeloma. The Validation of Novel Combination proposals should support the testing of several targeted therapeutic agents- either novel or currently available compound- in innovative, rationally-designed combinations and sequences. Proposals may request up to $100,000 for one year. Deadline: June 30

For more information, please click here.


Join hundreds of Case faculty, staff, and students in presenting your latest research and scholarship at Research ShowCASE, April 16-17.

Limited booth space available for active demonstrations of research. Only one request allowed per person.

Some booth space will be available for exhibits of centers or facilities that provide research support services for the university and/or its affiliates. Case CCC Core Directors are encouraged to present. Space is limited, so please submit your request to present as soon as possible. Deadline to submit is January 31. For more information, click here.


**All events are open to anyone interested in attending

January 14

Cancer Genetics/ Biology Journal Club cancelled

Leukemogenesis/ Cytokine Signaling Working Group Meeting
Henry Koon, MD
Assistant Professor, Medicine- Hem/Onc
Topic: NPM-ALK Signaling in Anaplastic Large Cell Lymphomas – Mouse Model Development
2:00 pm WRB 2-136

Physiology & Biophysics Seminar
Eckhard Ficker, PhD
Assistant Professor, Medicine
CWRU/ MetroHealth
Topic: HERG Channel Trafficking: Novel Targets in Drug-Induced Long QT Syndrome
4:00 pm SOM E531

January 15

Program Leaders meeting cancelled

January 16

Developmental Therapeutics Program Meeting cancelled

Grand Rounds
Lisa Filipovich, MD
Professor, Pediatrics- Hem/Onc Cincinnati Children's Hospital
Topic: Hemophagocytic Lymphohistiocytosis and Related Disorders
8:00 am Lerner B-151

January 17

Stem Cell Biology Seminar
Jeremy N. Rich, MD
Associate Professor, Neurology, Pharmacology & Cancer Biology, and Surgery
Duke University
Topic: Cancer Stem Cells: Do They Live Up to the Hype?
10:00 am NE1-205 Cleveland Clinic

Taussig Cancer Center Core Curriculum Series
David Peereboom, MD
Associate Professor, Hematology & Medical Oncology
CWRU/ Cleveland Clinic
Topic: Primary Brain Tumors: State of the Art: 2008
12:00 pm R3-002 Cleveland Clinic

Neuroscience Seminar
Zu-Hang Sheng, PhD
Chief, Synaptic Function Section
Topic: Control of Axonal Mitochondrial Mobility and Its Impact on Synaptic Transmission
12:10 pm BRB 105

Neuroscience Seminar
Marie-Francoise Chesselet, MD, PhD
Reed Neurological Research Center
Topic: Learning About Parkinson's Disease from Genetic Mouse Models
3:00 pm BRB 105

TREC Seminar
Sanjay Patel, PhD
Assistant Professor, Medicine
Topic: Sleep and Weight Regulation
4:00 pm BRB 732

January 18

Hematology/Oncology Fellows
Topic: TBA
8:00 am Wearn 137

Taussig Cancer Center Grand Rounds
John Sweetenham, MD
Professor, Hematologic Oncology & Blood Disorders
CWRU/ Cleveland Clinic
Topic: Changing Prognosis for Patients With Follicular Lymphoma-Present and Future Studies
8:00 am R3/002-003 Cleveland Clinic

Cell Biology Seminar
Randal Kaufman, PhD
University of Michigan
Topic: ER Stress, and the Unfolded Protein Response
10:00 am NC1-202 Cleveland Clinic

Cancer Center Seminar Series/ Blood Club
Caryn Lerman, PhD
University of Pennsylvania
Topic: Transdisciplinary Approach to Tobacco Control and Cancer Prevention
12:00 pm BRB 105


For a complete listing of LRI seminars click here.


Inflammation, Infection & Cancer Basic Science Focus Group Meeting
January 25
3:00 pm WRB 3-136

Regulation of Cell Death- Apoptosis & Autophagy Basic Science Focus Group Meeting
February 5
3:00 pm WRB 3-136

Prevention and Control Seminar
February 21
Siran Koroukian, PhD
Assistant Professor, Epidemiology & Biostatistics
Topic: Trajectory Care in Elders With Cancer
3:30 pm Wearn 137

Tumor Cell Adhesion, Growth Factor Receptor Signaling, Stromal Interactions, Migration and Metastasis Basic Science Focus Group Mini Retreat
February 26
1:00 pm WRB 2-136


**For more information on these symposiums, please contact Christine Rhoads.

Geriatric Oncology and Primary Care: Promoting Partnerships in Practice and Research
April 3-4
Dively Center
Course Directors: Nathan Berger, MD and Julia Rose, PhD

Update on Cervical Cancer Prevention: New Technology, New Evidence, and New Recommendations
April 18
Ritz Carlton Cleveland
Course Directors: Stephen Waggoner, MD and Kristine Zanotti, MD

Annual Update on Breast Cancer: Highlights of the National Meetings
June 13
Hilton Cleveland East, Beachwood

CALL FOR ABSTRACTS – International Society for Stem Cell Research 6th Annual Meeting

June 11-14
Pennsylvania Convention Center
Philadelphia, PA

The ISSCR Annual Meeting provides an opportunity to hear groundbreaking research from all areas of stem cell science. The meeting is an excellent forum for scientists to present and discuss their latest research, with participants from academic, industry and government setting from around the world.

Submission deadline: February 7 (12:00 pm CST)

For details, please click here.

FUNDING OPPORTUNITIES – 2008 Prostate Cancer Research Program

Department of Defense FY08 Prostate Cancer Research Program (PCRP) Announcements are expected to be released between January and February 2008. The announcements will describe opportunities for funding by the following award mechanisms:

  • Health Disparity Research Award

  • Health Disparity Training Award

  • Clinical Consortium Award

  • Clinical Trial Award

  • Laboratory - Clinical Transition: Stage 1 Award

  • Idea Development Award

  • Synergistic Idea Development Award

  • New Investigator Award

  • Collaborative Undergraduate Historically Black Colleges and Universities HBCU) Student Summer Training Program Award

  • Physician Research Training Award

  • Prostate Cancer Training Award

Brief descriptions of each of these mechanisms are being released in the News Release on the CDMRP website.

Requests for e-mail notification when Program Announcements are released may be sent to

FUNDING OPPORTUNITY – Ohio Cancer Research Associates

Seed money grants are available from Ohio Cancer Research Associates. The independent organization offers $25,000 for two years through its annual competition. The grants awarded by Ohio Cancer Research Associates are made to support research activities broadly related to cancer and leukemia. The organization seeks to fund research that will lead to continued support at the national level.

Ohio Cancer Research Associates grants are design to encourage junior faculty to apply. Full professors are not eligible to apply and applicants must be within six years of their first independent research position.

Ten to twelve grants will be awarded in 2008.

Application Deadline: February 22

For more information, click here, or call (800) 232-6272.

FUNDING OPPORTUNITY – DOD Breast Cancer Research Program

The Department of Defense Breast Cancer Research Program (BCRP) is currently accepting applications for the FY07 BCRP Concept Award.

The BCRP challenges the scientific community to design innovative research that will foster new directions for, address neglected issues in, and bring new investigators to the field of breast cancer research. The BCRP focuses its funding on innovative projects that have the potential to make a significant impact on breast cancer, particularly those involving multidisciplinary and/or multi-institutional collaborations and alliances. The BCRP encourages risk-taking research; however, all projects must demonstrate solid judgment and rationale.

Pre-application Deadline: January 9
Proposal Submission Deadline: January 23

For more information, please click here.


Pfizer Scholars Grant in Health Policy
Deadline: January 15

Pfizer Scholars Grants in Public Health
Deadline: January 15

Pfizer Fellowship in Health Disparities
Deadline: January 15

Pfizer Fellowship in Health Literacy/ Clear Health Communication
Deadline: January 15

Canary Foundation/ American Cancer Society
Deadline: January 16

Goldhirsh Foundation Brain Tumor Research Award Program
Deadline: January 16

NIH Director's Pioneer Award Program
Deadline: January 16

DOD Breast Cancer Research Program
Deadline: January 23

Lymphatic Research Foundation
Deadline: January 24

Ohio Department of Development Third Frontier Project
Deadline: January 28

Samuel Waxman Cancer Research Foundation
Internal Deadline: February 1

AACR Centennial Postdoctoral Research Fellowships in Cancer Research
Deadline: February 1

AACR Centennial Pre-doctoral Research Fellowships in Cancer
Deadline: February 1

Littlefield-AACR Grants for Metastatic Colon Cancer Research
Deadline: February 1

Lasker Foundation, Albert and Mary Medical Research Awards Program
Deadline: February 1

Lasker Foundation Awards, Basic Medical Research, Clinical Medical Research, and Special Achievement in Medical Science
Deadline: February 1

Jane Coffin Childs Memorial Fund for Medical Research
Deadline: February 1

2008 CWRU Presidential Research Initiative (PRI)Grant Program
Deadline: February 4

Ohio Cancer Research Associates
Deadline: February 22

Nancy R. Gelman Foundation
Deadline: February 22

Leukemia and Lymphoma Society Translational Research Program
Deadline: March 1

Lady Tata Memorial Trust International Award for Research in Leukemia
Deadline: March 1

Ladies Auxiliary to the Veterans of Foreign Wars (VFW) of the United States
Deadline: March 8

McDonnell Foundation Research Awards
Deadline: March 12

Lance Armstrong Foundation Research Grants
Deadline: March 14

NIH Shared Instrumentation Grant Program
Deadline: March 24

Lance Armstrong Foundation Community Grants
Deadline: March 24

Cancer Research Institute
Deadline: April 1

NIH Bulletin – Notices and Funding Opportunities

Notice Regarding the Applicability of the Federal Information Security Management Act to NIH Grantees (NOT-OD-08-032)

Revised Policy on Enhancing Public Access to Archived Publications Resulting from NIH-Funded Research (NOT-OD-08-033)

Selection of Appropriate Funding Opportunity Announcements (FOAs) for the Continuation of the Innovative Technologies for Molecular Analysis of Cancer (IMAT) Program (NOT-CA-08-003)

Comprehensive Minority Institution/Cancer Center Partnership (U54) (RFA-CA-08-001)

Innovative Technologies for Molecular Analysis of Cancer (R21)(RFA-CA-08-006)

Application for Emerging Technologies for Cancer Research (R21)(RFA-CA-08-007)

Application of Emerging Technologies for Cancer Research (R33)(RFA-CA-08-008)

Innovative Technology Solutions to Cancer Sample Preparation (R21)(RFA-CA-08-009)

Innovative Technology Solutions to Cancer Sample Preparation (R33)(RFA-CA-08-010)

Innovative and Applied Molecular Analysis Technologies for Cancer (SBIR [R43/R44]) (RFA-CA-08-011)

Innovative and Applied Molecular Analysis Technologies for Cancer (STTR [R41/R42])(RFA-CA-08-012)

Innovative Technology Solutions to Cancer Sample Preparation (SBIR [R43/R44])(RFA-CA-08-013)

Innovative Technology Solutions to Cancer Sample Preparation (STTR[R41/R42])(RFA-CA-08-014)

Decision Making in Cancer: Single-Event Decisions (R01)(PA-08-063)

Decision Making in Cancer: Single-Event Decisions (R21)(PA-08-064)

NIH Revision Awards for Studying Interactions Among Social, Behavioral, and Genetic Factors in Health (R01)(PAR-08-065)

NIH Revision Awards for Studying Interactions Among Social, Behavioral, and Genetic Factors in Health (R21)(PAR-08-066)

Produced by:
Gillian Irwin
11100 Euclid Avenue, Wearn 152
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax

Janice Green
11100 Euclid Avenue
Cleveland, Ohio 44106-5065
216-844-1862 phone
216-844-7832 fax
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