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Minh Lam, PhD

Assistant Professor, Dermatology

minh.lam@case.edu 216.368.0580 (o) 216.368.0212 (f)

Member, Nonprogrammatically Aligned

 

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Dr. Lam is exploring ideas that will lead to improvements in Pc 4-PDT, specifically facilitating its clinical development in treating cutaneous T cell lymphoma as well as other skin-related non-malignant diseases, including psoriasis. Recently, Dr. Lam has also been investigating the mechanism of action in Pc 4-PDT-induced apoptosis in the pathogenic yeast-like fungi, such as Trichophyton rubrum and Candida albicans in collaboration with Dr. Mahmoud Ghannoum, an expert in the area of fungal pathogenesis with special focus on adhesion and biofilm formation. Dr. Lam's other basic science interests in the laboratory include the Bcl-2 family proteins and the role(s) of calcium plays in apoptosis. Techniques that Dr. Lam frequently employs in his research include: Immunocytochemistry, qRT-PCR, Western blot, mammalian cell culture, molecular cloning, live-cell wide-field and confocal microscopy, FRET, FRAP and multiphoton microscopy.