Alex Y.C. Huang, MD, PhD
Co-Leader, Hematopoietic and Immune Cancer Biology Programalex.email@example.com 216.368.1271 (o) 216.844.5431 (f)
Associate Professor, Pediatric Hematology and Oncology
Our laboratory is interested in applying this and other classical immunological techniques to study various aspects of anti-tumor immune responses, immune – host – pathogen interaction, T cell-mediated memory immunity, and chemokine - receptor biology. Ongoing projects include:
6) Cellular and molecular mechanisms of metastasis in osteosarcoma, rhabdomyosarcoma and other common AYA and childhood cancer.
7) Mechanisms of immune checkpoint regulation in solid tumors.
8) Molecular mechanisms of T-cell Leukemogensis and CNS metastasis.
9) Exploring NK cell-based immunotherapy strategies against common pediatric and AYA cancers.
The long-term goal of our laboratory is to translate insights gained from basic investigations of in vivo immunity into rationally designed tumor vaccine and immunotherapeutic clinical trials, with a particular emphasis in the areas of pediatric sarcomas and other solid tumors in the pediatric and adolescent & young adult (AYA) populations.