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Magdelena M. Grabowska, PhD

Assistant Professor, Urology

mmg126@case.edu 216-368-5736 (o)

Member, GU Malignancies Program

 

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I am interested in the progression of prostate cancer from androgen-dependent to castrate-resistant prostate cancer. Although this progression can be achieved through multiple mechanisms, I am particularly interested in aberrant androgen receptor (AR) activation by dysregulation of co-factors (such as FOXA1 and nuclear factor I [NFI] family members) and the process of neuroendocrine differentiation following androgen-deprivation therapy and recurrence in advanced prostate cancer patients.