Magdelena M. Grabowska, PhD
Assistant Professor, Urologymmg126@case.edu 216-368-5736 (o)
Member, GU Malignancies Program
I am interested in the progression of prostate cancer from androgen-dependent to castrate-resistant prostate cancer. Although this progression can be achieved through multiple mechanisms, I am particularly interested in aberrant androgen receptor (AR) activation by dysregulation of co-factors (such as FOXA1 and nuclear factor I [NFI] family members) and the process of neuroendocrine differentiation following androgen-deprivation therapy and recurrence in advanced prostate cancer patients.