GENERAL MEDICAL SCIENCES (ONCOLOGY)

DAVID DANIELPOUR, PhD Associate Professor General Medical Sciences (Oncology) Phone: 216/368-5670 Fax: 216/368-8919 email: dxd49@case.edu

Research Interests

TGFβ

Selected Publications

Li N, Zheng L, Lin P, Danielpour D, Pan Z, Ma J. Overexpression of bax induces down-regulation of store-operated calcium entry in prostate cancer cells. J Cell Physiol. In press, 2008.

Guan L, Song K, Pysz MA, Curry KJ, Hizli AA, Danielpour D, Black AR, Black JD. Protein kinase C-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a phosphoinositide 3-kinase/Akt-independent, protein phosphatase 2A-dependent mechanism in intestinal epithelial cells. J Biol Chem 282:14213-14225, 2007.

Huang L, Pu Y, Hepps D, Danielpour D, Prins GS. Posterior hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. Endocrinology 148:1235-1245, 2007.

Noda D, Itoh S, Watanabe Y, Inamitsu M, Dennler S, Itoh F, Koike S, Danielpour D, Ten Dijke P, Kato M. ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-beta/Smad-induced growth arrest of prostate cells. Oncogene 25:5591-5600, 2006.

Chou YT, Wang H, Chen Y, Danielpour D, Yang YC. Cited2 modulates TGF-beta-mediated upregulation of MMP9. Oncogene 25:5547-5560, 2006.

Cai C, Lin P, Cheung KH, Li N, Levchook C, Pan Z, Ferrante C, Boulianne GL, Foskett JK, Danielpour D, Ma J. The presenilin-2 loop Peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis. J Biol Chem 281:16649-16655, 2006.

Song K, Krebs TL, Danielpour D. Novel permissive role of EGF in TGF-beta signaling and growth suppression: mediation by stabilization of TGF-beta receptor type II. J Biol Chem 281:7765-7774, 2006.