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February 9, 2015


Dr. Stan GersonStan Gerson, MD
Director, Case CCC

City Club Event Follow-up

As you know, last week the Case Comprehensive Cancer Center was featured in a forum discussion at the City Club of Cleveland Forum. Myself, Brian Bolwell, Ruth Keri and Neal Meropol highlighted the collaborative research efforts of the Cancer Center and attracted a packed house with over 200 people in attendance. The panel discussion was streamed live on the City Club website and also rebroadcast on WCPN radio and WVIZ TV. The forum was also made available to NPR affiliates nationally for rebroadcasting, and our message reached an audience of approximately 45,000 nationwide including NPR, web streaming and YouTube.

The event, The Annual Craig and Spangenberg Memorial Forum, was made possible by a special memorial gift from the law firm Spangenberg, Shibley & Liber where our Cancer Council Chair Peter Weinberger acts as the managing partner.

Video of the discussion, which was led by WCPN health reporter Sarah Tribble, is available on the City Club of Cleveland YouTube Channel. I encourage you to watch the video and share it with your networks.

Smoking Cessation Op-Ed

Following up on our City Club forum, Terry Allan and I are promoting the cigarette tax issue. While I would like to see support for cancer research as in most states, the greater good is smoking cessation.

Please take a look at our op-Ed in the Plain Dealer and the comments that followed: Tobacco Taxes Improve Health, Bottom Line in Ohio.


Eliciting the Patient's Experience of Illness through Narrative and Reflection

A factor that often gets overlooked when it comes to cultural competence is the patient's "voice" or "narrative and reflection" about their illness. Healthcare providers tend to be disease focused, while patients seek medical care because of their illness. This can cause disconnect to happen from a provider's treatment of disease and a patient's need for treatment of illness. Studies show that allowing and encouraging patients to tell their illness story can be transformative to the patient and provide important knowledge about the individual to the healthcare provider. Yet, narrative and reflection is a topic many are unfamiliar or uncomfortable with. [View entire entry plus action items]

Presentation with Voice-over
Eliciting the Patient's Experience of Illness through Narrative and Reflection by Paula Schultz BSN, RN, CNRN; UH Seidman Cancer Center, Office of Patient and Public Education: This 10 minute PowerPoint presentation considers the rationale behind and methods for eliciting the patient's experience of illness as a crucial part of patient centered, culturally competent care.

Mark Your Calendars

Graft versus Host Disease National Symposium

Registration is now open for the Graft versus Host Disease (GvHD) National SymposiumFriday, April 24, at the Embassy Suites Cleveland. This conference is intended to raise awareness about the signs and symptoms of GvHD, review cutting edge approaches to prevention and treatment, and highlight and promote research to further our understanding of its cause.

The symposium will have two tracks: a scientifically rigorous one for physicians and practitioners, and a survivor track that will focus on challenges faced by BMT recipients and their families. The survivor track is intended to provide both education and the opportunity for individuals to interact with national leaders in the GvHD field. The afternoon "Meet the Expert" uniquely interactive breakout sessions will provide an opportunity for the physicians, survivors and their families to come closely together during the program. Continuing Medical Education credits will be offered.

Case CCC Annual Scientific Retreat

The Case CCC Annual Scientific Retreat will be held July 9-10, 2015. The agenda is still being planned, but we hope you will set aside time to attend this important event! More details will be posted in future newsletters.


Patient-Centered Outcomes Research Institute - Improving Healthcare Systems

Patient-Centered Outcomes Research Institute (PCORI) is seeking applications to study the comparative effectiveness of alternate features of healthcare systems (e.g., innovative technologies, incentive structures, service designs) intended to optimize the quality, outcomes, and/or efficiency of care for the patients they serve and that have the most potential for sustained impact and replication within and across healthcare systems. Healthcare systems encompass multiple levels (e.g., national, state and local health environments, organization and/or practice settings, family and social supports, and the individual patient) and include entities organized to deliver, arrange, purchase, and/or coordinate healthcare services. PCORI seeks to fund studies that will provide information of value to patients, their caregivers, clinicians, and healthcare leaders regarding which features of delivery systems lead to better patient-centered outcomes so they may ultimately impact healthcare delivery.
LOI Deadline: March 6

Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families

The American Cancer Society has released an RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families. These funds will support projects focused on the development of the specialty of palliative medicine is a critical step in addressing the unmet needs of patients with serious illness and their families. Pilot data are typically needed before funding agencies (e.g., NIH, VA or the American Cancer Society) will consider funding a research project. In an effort to support clinician investigators conducting patient-oriented research in palliative care, the American Cancer Society, in parallel with the National Palliative Care Research Center (NPCRC), is soliciting applications for pilot/exploratory research grants in palliative care of cancer patients and their families. These grants will generate the pilot data necessary to maximize an investigator's chances of competing successfully for larger grants.
Deadline: April 1 and October 1

Clinical Oncology Research Career Development Program

The Case Comprehensive Cancer Center is accepting applications for the Clinical Oncology Research Career Development Program (CORP). The purpose of this program is to provide interdisciplinary training in clinical and translational oncology research for clinical oncology junior faculty physicians who are interested in pursuing academic research careers as physician scientists. This training addresses the need for clinician investigators to translate fundamental cancer research discoveries into medical care of cancer patients. Eligible candidates are physicians (MD, DO or MD/PhD) with a clinical training background in one of a number of oncology disciplines, including medical, surgical, pediatric, dermatological, gynecological and radiation oncology.

This career development program is supported by robust interdisciplinary clinical and translational research programs in the Case Comprehensive Cancer Center that provide Paul Calabresi Scholars the opportunity to select one of three areas of concentration:

  • Mechanism Based Therapeutics and Clinical Trials
  • Stem Cell Biology and Hematopoietic Malignancy Clinical Trials
  • Prevention, Aging and Cancer Genetics and Clinical Trials

Deadline: April 17


National Center for Accelerated Innovations (NCAI-CC)
Deadline: February 10, 2015

Case-Coulter Translational Research Partnership (CCTRP)
LOI Deadline: February 13

Leukemia & Lymphoma Society Translational Research Program (TRP)
LOI Deadline: February 15, 2015
Application Deadline: March 1, 2015

CWRU Skin Diseases Research Center Pilot and Feasibility Program
Deadline: February 27

Lila and Murray Gruber Memorial Cancer Research Award
Deadline: February 28, 2015

Ohio Cancer Research Associates
Deadline: February 28, 2015

Myeloma Research Foundation
Deadline: March 1, 2015

Bladder Cancer Advocacy Network 2015 Young Investigator Awards
Deadline: March 4, 2015

Multiple Myeloma Senior Research Grants
Deadline: March 17

Taub Foundation Grants Program for Myelodysplastic Syndromes (MDS) Research
Initial Proposal Deadline: March 17
Invited Proposal Deadline: August 14

Limited Submission: National Science Foundation Collections in Support of Biological Research (CSBR)
Internal Deadline: March 23, 2015
External Deadline: July 13, 2015

ASTRO Residents/Fellows in Radiation Oncology Research Seed Grants
Deadline: March 27

American Cancer Society: The Role of Health Policy and Health Insurance in Improving Access to and Performance of Cancer Prevention, Early Detection, and Treatment Services
Deadline: April 1

Multiple Myeloma Research Fellow Awards
Deadline: April 21

Worldwide Cancer Research
Deadline: April 24, 2015

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

Support of Multi-investigator Initiatives in the Case CCC
Deadline: Open

Collaborative Activity Awards
Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to Gillian Irwin at


Tues, Feb 10

Molecular Genetics Research Seminar
Elizabeth Hulme Berezovsky, PhD
Postdoctoral Research Fellow, Runge Lab, Molecular Genetics
Cleveland Clinic
Topic: Mechanistic Action of the Lifespan-Extending Drug Plumbagin
9:30 am NE1-205 Cleveland Clinic

Immunology Seminar Series
Jaffre Athman
Harding lab, Immunology
Topic: Bacterial Vesicles & Immune Evasion During Mycobacterium tuberculosis Infection
12 pm WRB 1-413

Pharmacology Seminar
John Feng, PhD
Department of Pathology
12 pm W331/Webster conference room

Translational Hematology & Oncology Research
Kevin Peters, PhD
Hewlett Packard
Topic: Digital Titration & Combinations in Oncology Discovery, Clinical Research, and Quantitative Functional Diagnostics for Precision Medicine
1 pm R3-027 Cleveland Clinic

Cancer Biology Seminar
Madhumita Pradhan, PhD
Research Fellow, Sharifi Lab, Cancer Biology
Cleveland Clinic
Topic: Differential Regulation of Androgen Receptor Signaling in Prostate Cancer Cells
2 pm NC1-202 Cleveland Clinic

DNA Damage/Repair Meeting
David Wald, MD, PhD
Assistant Professor, Pathology
4 pm WRB 3-136

Wed, Feb 11

Hem/Onc Division Research Conference
8 am Lerner B-151

Immunology Seminar
Jim Finke, PhD
Professor, Immunology
Cleveland Clinic
Topic: Role and Modulation of Myeloid Derived Suppressor Cells in Kidney Cancer and Melanoma
12 pm in NC1-202 Cleveland Clinic

Thurs, Feb 12

Immunology Journal Club
Hana Russo
Department of Immunology
Topic: The TCR's Sensitivity to Self Peptide-MHC Dictates the Ability of Naïve CD8+ T Cells to Respond to Foreign Antigens
12 pm WRB 5-136

Molecular Biology and Microbiology Seminar
Ryan Stultz
McDonald lab, Molecular Biology & Microbiology
Topic: Visualizing Intracellular HIV in Primary Human Macrophages
1 pm Rottman Seminar Room W203

Fri, Feb 13

Hem/Onc Fellows
Faculty Facilitator: Shaveta Vinayak, PhD
Fellows: Peter Oppelt, MD and Nicole Williams, MD
Div. of Hem/Onc
CWRU/UH Topic: Cancer Biology Series: DNA Repair Pathways
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Steven P. Balk, MD, PhD
Professor, Medicine
Harvard Medical School
Staff Physician, Hematology/Oncology
Beth Israel Deaconess Medical Center
Topic: Androgen Receptor in Prostate Cancer Development
8 am R3/002-003 Cleveland Clinic

Cellular and Molecular Medicine Seminar Series Staff Candidate
Changcheng Zhou, PhD
Department of Pharmacology & Nutritional Sciences, Saha Cardiovascular Research Center
University of Kentucky
Topic: Xenobiotic Exposure, Inflammation and Metabolic Disorders
10 am NC1-202 Cleveland Clinic

Cancer Center Seminar Series
Steven P. Balk, MD, PhD
Professor, Medicine
Harvard Medical School
Staff Physician, Hematology/Oncology
Beth Israel Deaconess Medical Center
Topic: Mechanisms Driving Prostate Cancer Development and Progression
12 pm BRB 105

Cancer Center Research In Progress Seminar
David Danielpour, PhD
Professor, General Medical Sciences (Oncology)
Topic: Therapeutic Targets in Prostate Cancer
4 pm WRB 3-136

Mon, Feb 16

Genomic Medicine Institute Seminar
Chunlei Zheng
Zhang lab, Genomic Medicine Institute
Cleveland Clinic
Topic: RNA-Seq Analysis of Genetically Modified Mice Suggests New Functions of the LMAN1-MCFD2 Cargo Receptor
12:30 pm NC1-205 Cleveland Clinic

Skeletal Research Center
Veronique Lefebvre, PhD
Staff/Professor, Cellular & Molecular Medicine, Orthopaedic and Rheumatologic Research Center
Cleveland Clinic
Topic: Actions and Regulation of the Master Chondrogenic SOX5/6/9 Trio
4 pm Millis 123

Tues, Feb 17

Radiation Oncology Grand Rounds
Elizabeth Weinstein, MD, MS
Medical Director, Supportive Oncology
Assistant Professor, Hospice and Palliative Medicine
Topic: Cancer Pain: A Rapid Review (and a couple symptoms)
8:10 am Lerner B-151

Translational Hematology & Oncology Research
Shunji Egusa, PhD, THOR 
Translational Hematology & Oncology Research
Cleveland Clinic
1 pm R3-027 Cleveland Clinic

Cancer Biology Seminar
Shuvojit Banerjee, PhD
Research Associate, Silverman Lab, Cancer Biology
Cleveland Clinic
Topic: Roles of RNase L in Inflammasome Activation and Innate Immunity
2 pm NC1-202 Cleveland Clinic

Wed, Feb 18

Hem/Onc Division Research Conference
8 am Lerner B-151

CFAR/Frontiers Seminar
Robert Siliciano
Johns Hopkins University
Topic: Visualizing Intracellular HIV in Primary Human Macrophages
4 pm WRB 1-413

Thurs, Feb 19

Cancer Biology Trainee Seminar 
12 pm WRB 3-136

Fri, Feb 20

Hem/Onc Fellows
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
W. Kimryn Rathmell, MD, PhD
Translational Research Director, MD-PhD Program
Associate Professor, Medicine and Genetics
Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill
Topic: Translational Studies in Renal Cancer
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
W. Kimryn Rathmell, MD, PhD
Translational Research Director, MD-PhD Program
Associate Professor, Medicine and Genetics
Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill
Topic: Translational Studies in Renal Cell Carcinoma
12 pm BRB 105

Cancer Center Research In Progress Seminar
4 pm WRB 3-136


Case CCC Calendar

LRI Calendar


Multidisciplinary Head and Neck Cancer Update
Weston, FL
March 6-7, 2015

Graft Versus Host Disease Symposium 2015
April 24, 2015
Embassy Suites Cleveland - Rockside

Advances in Lung Cancer: A Multidisciplinary Approach
April 25, 2015
Marriott Hotel at Key Center

ASCO Review
June 26, 2015
InterContinental Hotel


Symposium on Global Cancer Research
March 25, 2015
Boston Sheraton Hotel