MESSAGE FROM THE DIRECTOR
Stan Gerson, MD
Director, Case CCC
NCI Annual Plan and Budget Proposal for FY 2016
Dr. Harold Varmus, Director of the National Cancer Institute (NCI), has issued the NCI's Annual Plan and Budget Proposal for the National Cancer Program for Fiscal Year 2016. The narrative that accompanies the so-called "bypass budget" highlights promising directions in cancer research and requests a level of federal funding that would allow us to make more rapid progress towards reducing the burden of cancer in the United States and around the world during these fiscally austere times.
I had the opportunity to read through the document and encourage you to do so as well. I would note the following:
- It is well written without the jargon most of us use to describe our science, even when the concepts are quite sophisticated.
- It is clear about NCI priorities and I would note the emphasis on basic science of RAS, the value of genomics and big data, the importance of technology, the clinical genomic trials, issues of disparities, and the importance of prevention.
- The NCI makes the case of the need for increased funding of research, but is realistic that this may not occur soon.
Please have a look.
Geography May Limit Access to Cancer Clinical Trials
Reuters - December 4, 2014
Where advanced cancer patients live affects the likelihood that they can enroll in a treatment clinical trial, a new study found. Fewer than 10 percent of U.S. cancer patients participate in clinical trials, the authors note..."Clinical trials offer several potential benefits for the patients who participate," said Dr. Neal J. Meropol, of Case Western Reserve University and University Hospitals Case Medical Center in Cleveland, Ohio. He was not involved in the study. "They provide access to a novel therapeutic opportunity, offer hope, and ensure careful attention from the team of nurses and doctors involved in the study," Meropol told Reuters Health by email.
CASE Researcher Wins $2.4M Grant
Ideastream - December 2, 2014
An assistant professor at Case Western Reserve University's School of Medicine is the latest person to be honored by the National Institutes of Health as a new innovator – winning an award of $2.4 million for her work designing computer programs that could determine if drugs already in use...could also be used to help patients with 'other' conditions. Ideastream's Rick Jackson talked with Rong Xu at the Case Western Reserve School of Medicine and Case Comprehensive Cancer Center– where she explained the vision behind the design.
Fertility Hope for Cancer Patients
News 4 Jax - December 1, 2014
Stephanie Moisio had just married her best friend when doctors told her she had stage-two breast cancer...Stephanie chose to freeze her eggs and Cleveland Clinic doctor Halle Moore offered her an additional option – the injectable drug goserelin it's a synthetic hormone that puts a woman's ovaries in a "resting" state. "To basically put them in a temporary menopause during the chemotherapy treatment in the hopes of improving prospects for long-term ovarian function," explained Halle Moore, MD, Medical Oncologist at Cleveland Clinic and member of the Case Comprehensive Cancer Center.
Tumor Markers in Older Patients With Early Breast Cancer: Why Are We Still Doing Useless Tests?
December 1, 2014 - Journal of Clinical Oncology
Editorial written by Drs. Lyndsay Harris and Cynthia Owusu of Seidman Cancer Center and the Case Comprehensive Cancer Center.
Introduction to the Cultural Competency Series
Case CCC leadership continuously works to provide equal access to research studies for all patients in our catchment area. While our leadership recognizes that achieving a clinical trial participant population that mirrors the overall minority patient population may not be feasible for many reasons that are similar to those faced by other institutions, this remains the Case CCC goal. In an effort to minimize the gap between minority and non-minority patient participation in clinical trials, the Case CCC has undertaken a variety of activities in areas such as research, education, and outreach. A structured approach was facilitated by the establishment of a Minority Accrual Task Force, now a standing Case CCC Minority Accrual Committee (MAC). MAC members represent all of the Case CCC participating institutions, as well as the community.
Activities of the Task Force and MAC include organizing retreats covering issues of clinical trial accrual of minority populations (2011) and cultural competency (2014).
As a result of the cultural competency retreat, Case CCC would like to introduce the Cultural Competency Series as a standard feature in the Case CCC Newsletter and on the Clinical Research Portal web page. The main objectives for the Cultural Competency Series are to provide investigators and research staff opportunities to develop different skill sets, to engage in a meaningful dialogue about the importance of cultural competency in the context of health care and research, and to facilitate concepts of self-reflection and self-critique.
We hope to continue raising awareness and acceptance of the dynamic variety of people and communities the Cancer Center serves, and in providing clinical research staff with unique learning experiences and skills to conduct culturally competent research. The Cultural Competency Series will include information, resources, audio clips and videos. Questions, suggestions and feedback about the Cultural Competency Series should be directed to Katarzyna Karelus at email@example.com or 216.844.4176. [more]
Operationalizing Culturally Competent Research
We are pleased to start off the Case CCC Cultural Competency Series with a keynote address presented by Sonja Harris-Haywood, MD, MS, at the Case CCC Cultural Competency Retreat on March 13, 2014.
The audience of Dr. Harris-Haywood's presentation, Operationalizing Culturally Competent Research, will be introduced to the following concepts: 1) Background information of diversity of racial and ethnic groups in cancer clinical trials; 2) Definition of culturally competent research; 3) How to operationalize a culturally competent research process; and 4) Issues related to study design and publishing criteria for increasing diversity of clinical trial participants.
The presentation will take the viewer through research process steps starting with posing a research question through study design, recruitment, data collection, data analysis and dissemination of findings. It will show, using general and specific examples, how culturally competent research can increase the inclusion of minorities in cancer clinical trials. Viewing the presentation and taking an online quiz will allow you to receive 3 Continuing Research Education Credits (CRECs). [more]
New Biographical Sketch Format Required for NIH and AHRQ Grant Applications Submitted for Due Dates on or After January 25, 2015
The National Institutes of Health (NIH) Agency for Healthcare Research and Quality's (AHRQ) will require use of a new biosketch format in applications for research grantssubmitted for due dates on or after January 25, 2015. Between now and that time, applicants will have the choice of using the old or new biosketch format. The transition to the new biosketch format follows a Request for Information and a series of pilot Funding Opportunity Announcements (FOAs) using the new format over the last year. Input from the pilots suggests that the instructions for the new forms were clear and that a majority of the applicants and reviewers felt that the new format would be helpful in describing the past experience and qualifications of researchers. The revised forms and instructions are now available on theSF 424 (R&R) Forms and Applications page. The new format extends the page limit from four to five pages, and allows researchers to describe up to five of their most significant contributions to science, along with the historical background that framed their research. Investigators can outline the central findings of prior work and the influence of those findings on the investigator's field. Investigators involved in Team Science are provided the opportunity to describe their specific role(s) in the work. Each description can be accompanied by a listing of up to four relevant peer-reviewed publications or other non-publication research products, including audio or video products; patents; data and research materials; databases; educational aids or curricula; instruments or equipment; models; protocols; and software or netware that are relevant to the described contribution. In addition to the descriptions of specific contributions and documentation, researchers will be allowed to include a link to a full list of their published work as found in a publicly available digital database such as MyBibliography or SciENcv.
CTSC Annual Pilot Award
The CTSC Annual Pilot Program is for researchers to conduct innovative translational research projects focused on the invention, preclinical development and/or first in man studies of novel therapeutic agents, biomedical devices, and diagnostics designed to address unmet clinical needs. Funding is intended to facilitate development of enabling technologies; new therapeutic, diagnostic or outcomes assessment approaches and/or device; novel cross-disciplinary collaborative programs; and promote research in the community. Research which may create intellectual property is encouraged. If funding would enhance an existing non-federally funded project or enable a proposal to a federal agency for use of CTSC and CCTRP resources, the application would be considered. This pilot has few restrictions and allows for the hiring of personnel. Researchers new to clinical research, clinical research scholars, or experienced researchers who are moving into a new area of research are strongly encouraged to apply.
LOI Deadline: January 15, 2015
American Brain Tumor Association (ABTA) 2015 Research Funding Opportunities
The American Brain Tumor Association (ABTA) is now accepting applications for the 2015-2017 Basic Research Fellowships and 2015 Medical Student Summer Fellowships.
ABTA Basic Research Fellowships are $100,000 awards payable over a two-year period. The fellowship provides $45,000 in salary support and $5,000 in researcher discretionary funds per annum. The discretionary funds are intended for research equipment, supplies, or travel to appropriate scientific meetings, but must include a trip at the end of the award period to present research results. The fellowship award may be used only for salary support and researcher discretionary funds; indirect expenses cannot be allocated from the award. Studies are to be conducted at laboratories in the United States or Canada. Applicants should be on-track to pursue a career in brain tumor research with a sponsor who has a demonstrated history of brain tumor research and mentorship.
Deadline: January 7, 2015
ABTA Medical Student Summer Fellowships are $3,000 grants available for medical students to spend a summer conducting brain tumor research. The fellowship is to be conducted in a neuro-oncology laboratory with a mentorship setting that will provide an introductory learning experience. Studies are to be conducted at laboratories in the United States or Canada. The fellowship start date is determined by the sponsor and should extend 10-12 weeks over the summer. A student authored outcomes report is due upon completion of the Fellowship, and must be received by October 1, 2015.
Deadline: January 28, 2015
GI SPORE: Request for Project Proposals
All Faculty members are invited to submit concept proposals for five-year Projects to compete for incorporation as a full project proposal in the upcoming GI SPORE competing renewal application that will be prepared starting in January 2015 for submission in September 2015.
All proposals must be directed towards translational research of a GI malignancy, with at least one specific aim that involves direct study of patients or of human tissues. Proposals must include two project leaders: one Basic Science leader and one Clinical leader. Previously submitted SPORE pilot applications are welcome to be resubmitted as full projects, and may be updated with any new progress.
Deadline: January 16, 2015
Leukemia & Lymphoma Society
The Leukemia & Lymphoma Society (LLS) Translational Research Program (TRP) puts you on the bench-to-bedside fast track when it comes to finding better treatment and cures for leukemia, lymphoma and myeloma. The LLS funds new and innovative research that shows high promise for translating basic biomedical knowledge to clinical application. The goal of translational research is to reduce the time between laboratory findings and actual treatment
LOI Deadline: February 15, 2015
Application Deadline: March 1, 2015
Call for Applications: Computational Genomic Epidemiology of Cancer (CoGEC) Training Program
The Case Comprehensive Cancer Center invites applications to its Computational Genomic Epidemiology of Cancer (CoGEC) Training Program for research associates, for a start date of August 1, 2015. This program combines a mentored cancer research project designed by the fellow in collaboration with their mentors with a specialized curriculum of formal didactic training and individualized longitudinal curriculum.
This program is designed to prepare research associates for careers as: Independent investigators engaged in research at the intersection of cancer research, genetics, epidemiology, biostatistics, and computer science. Cancer researchers obtaining training will have the skills vital to decipher the complex pathways compromised of genetic and environmental risk factors for disease, and will ultimately be able to provide clinicians and their patients with valuable information for the prevention and treatment of cancer. Salary and research supply funds are highly competitive.
- US citizenship or permanent residency.
- Terminal degree (PhD, MD or MD/PhD).
- Demonstrated skills in quantitative analysis and an interest in a career in cancer genetics research.
Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Research
Ohio Cancer Research Associates
Collaborative Activity Awards
HELP US HELP YOU!
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