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September 29, 2014


Design of Cleveland Clinic's New Cancer Institute Packs a Subtle Precision and Clarity
The Plain Dealer - Sept 27, 2014
The Cleveland Clinic's newest architectural project, a $276 million Cancer Institute, certainly qualifies as a big addition to the institution and the city...Rawn worked with Dr. Brian Bolwell, chairman of the Taussig Institute and his principal client on the project, to design treatment clusters in which doctors and nurses will specialize in various aspects of cancer care.

Cleveland Clinic, UH Share in $1 Million Donation from Cohen Family for Cancer Genomics
The Plain Dealer - Sept 24, 2014
A Shaker Heights family has donated $1 million to the city's largest hospitals to help advance cancer genomics " the method of studying the genes of cancer patients to help improve and personalize their care. The Cleveland Clinic and University Hospitals will share the gift from the family of Joanne and Margaret Cohen, which establishes the Rosalie and Morton Cohen Family Memorial Genomics Fund at each institution.

The Cohens' parents, the late Morton and Rosalie Cohen, made a $1.5 million gift to the UH Seidman Cancer Center in 2007 to establish the Rosalie and Morton A. Cohen Chair in Lung Cancer in honor of UH Seidman Cancer Center President Dr. Nathan Levitan, who cared for Rosalie Cohen during a long treatment for lung cancer.

"This generous gift from the Cohen family provides a unique opportunity for us to support the entire region," said Dr. Brian Bolwell, chairman of the Clinic's Taussig Cancer Institute. "With a large majority of cancer patients in Northeast Ohio being seen at either a Cleveland Clinic or University Hospitals facility, we are uniquely positioned to make a significant impact in this new era of cancer care and research."...

"Genomics is the new frontier of cancer research and the Cohen family's gift will help the Cleveland cancer research community to make further advancements in this rapidly growing field," Dr. Stan Gerson, director of the UH Seidman Cancer Center and the Case Comprehensive Cancer Center at Case Western Reserve University, said in a news release.

The Rosalie and Morton Cohen Family Memorial Genomics Fund, which will be divided equally between the Clinic and UH over three years, will be used to expand genomic sequencing access to under-served populations across the region who have some of the highest mortality rates statewide.

Case Western Reserve University on Track to Become No. 1 Synchrotron Lab in World
Newswise - Sept 23, 2014
Case Western Reserve University's synchrotron facility at Brookhaven National Laboratory is on its way to becoming the No. 1 beamline facility for biology in the world by early 2016, thanks to a jumpstart grant of $4.6 million from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), a component of the National Institutes of Health (NIH)..."When NSLS-II opens, the lab's beamlines will have the brightest, most intense x-ray beams — 100 times brighter than beamlines anywhere in the world," said Mark Chance, PhD, director of the Center for Proteomics and Bioinformatics, Case Western Reserve University School of Medicine. "With this technology, NSLS-II will collect data 100 times faster than any other synchrotron facility in the world."


Quality of Life Research Seminar

Register today to attend a Quality of Life Research Seminar,Statistical and Methodological Strategies in Quality of Life Studies, on October 8, 8:45 - 10:15 am in the Wolstein Research Building Auditorium. Presenter Dr. Diane Fairclough is renowned for her research in Quality of Life, outcomes in palliative/hospice care, and psychosocial sequelae of cancer and its therapy in pediatric and adult patients. Her statistical research interests include the analysis of longitudinal studies with non-random missing data due to disease morbidity or mortality. Dr. Fairclough is past president of the International Society for Quality of Life Research, has over 200 peer-reviewed publications, and is the author of Design and Analysis of Quality of Life Studies in Clinical Trials, 2nd edition (2010).

3 CRECs are available to attendees. Please RSVP to Dr. Mary Jo Price-Paul ( or Barbie Boveington-Molter (

Fall 2014 Case CCC Clinical Research Retreat

The Case CCC will be holding a Clinical Research Retreat on October 7 in the Wolstein Research Building. A reception will be held from 5-5:30 pm, followed by presentations from 5:30-7 pm.

The agenda will focus on the theme of Immunotherapy:

James Finke, PhDStrategies to Reduce Immune Suppression as a Means to Improve Immunotherapy: A laboratory perspective

Joseph Baar, MDRecent Advances in the Immunotherapy of Cancer

Shaveta Vinayak, MDTumor Infiltrating Lymphocytes Predict for Response to Therapy in Triple-negative Breast Cancer

Mitchell Machtay, MDNational Clinical Trials Network/Cooperative Groups (NCTN) Update

Pre-registration is required. Please contact Dr. Smitha Krishnamurthi ( with any questions. We hope everyone interested in clinical trials can attend!

2014 Adolescent and Young Adult Cancers Symposium

This first Adolescent and Young Adult (AYA) cancer conferencehosted by the Case Comprehensive Cancer Center is being held October 30-31 at the Iris S. & Bert L. Wolstein Research Building. This collaborative symposium is organized by the Angie Fowler Adolescent & Young Adult Cancer Institute at University Hospitals Rainbow Babies & Children's Hospital, UH Seidman Cancer Center, Case Comprehensive Cancer Center, and the Oregon Health & Science University Knight Cancer Institute. The focus of this two-day symposium is on advancement of AYA-related cancer research, including exploration of scientific, clinical and psychological considerations in adolescent and young adult cancer patients.

The symposium features speakers from leading academic institutions and non-profit organizations who are at the forefront of AYA research and advocacy, including Heidi Adams, CEO of Critical Mass, and Simon Davies, CEO of Teen Cancer America. We are excited to feature two key speakers from University Hospitals Case Medical Center, Dr. Henry Koon, Disease Team Leader of Melanoma and Dr. Cheryl Kingsberg, Division Chief Ob/GYN Behavioral Medicine, CWRU Obstetrics and Gynecology, University Hospitals MacDonald Women's Hospital.

The symposium also features a keynote address by Clifton Leaf, Deputy Managing Editor, "Fortune Magazine," and author, "The Truth in Small Doses: Why We're Losing the War on Cancer And How to Win It." Mr. Leaf is a cancer survivor and a national advocate for change to the way the global cancer fight is funded and pursued, pushing for ways to speed up progress against the disease. Mr. Leaf has presented testimony to the President's Cancer Panel three times, given a plenary address at the annual meeting of the American Association for Cancer Research, and delivered Grand Rounds at the National Cancer Institute, the only journalist to be given that honor.

We hope that you will join us this year for our first AYA cancer conference, and we hope that we can help you connect to an international community of researchers and advocates for the AYA cancer community. Register today! Continuing Medical Education credits are available.



Support of Case CCC Scientific Program Projects

Proposals are requested from the Case CCC Scientific Programsaddressing unique research opportunities, innovative ideas or areas identified as strategically important to the program. Proposals must be for projects that are aligned with the goals described in the Cancer Center Strategic Plan. They may build on the institutional investments in genomics and informatics, drug screening and discovery, promote the development and use of new technologies, foster new collaborations or strengthen existing research teams through the development of new research areas aligned with the scientific program strategic plan. Attention to catchment area related research is preferred. Proposals should be multi-investigator in nature, with inclusion of translational or clinical research projects.

Each program is asked to submit one response to this RFA.Program leaders must be engaged in identifying potential areas or recommending topics and proposals for the program. Proposals must be reviewed by a committee within the program that is convened specifically for this purpose before being submitted to the Cancer Center Executive Committee. The Executive Committee will make the final determination for funding after evaluating proposals and reviews. It is expected that the research projects will lead to nationally competitive grant proposals from multi-investigator teams.
Deadline for Submission to Program Leaders: November 7 
Deadline for Submission of priority proposals to Executive Committee: December 15

Alex's Lemonade Stand Foundation Innovation Grant

Alex's Lemonade Stand Foundation (ALSF) is committed to creating opportunities for new and innovative research into treatments and cures for childhood cancers. Innovation grantsare designed as seed funding for researchers with a novel approach to pediatric oncology scientific investigation. This may represent a change in research direction and/or an innovative new idea that moves away from an investigator's prior research but has potential impact for childhood cancers. Innovation Grants will support research proposals to be carried out by investigators who are already established, have a track record of peer-reviewed publications and evidence of successfully competing for extramural funding. The grant is for two years up to $125,000 per year. A one year no cost extension is encouraged.
LOI Deadline: December 3

Support of Multi-investigator Initiatives in the Case CCC

The Case CCC will provide two modes of support to new research teams that plan to submit large multi-investigator grant applications (usually non-R support mechanisms).

  • Administrative support and funding for travel are available to encourage team member meetings and meetings with external advisors.
  • Pilot project funding for research teams with an established track record of collaborative research is available to support key research initiatives that are necessary to generate competitive multi-investigator proposals.

Requests are competitive. The research team must demonstrate the active engagement of members, clearly articulate the significance and innovation of the project, and provide a roadmap for acquisition of external funding. Advocacy and support of the specific program leadersinteracting with the team is required. Discussion with Ruth Keri, PhD, Associate Director for Basic Research, is strongly encouraged before developing an application.

Deadline: Open


Conquer Cancer Foundation Advanced Clinical Research Award (ACRA)
Deadline: September 30

Szent-Györgyi Prize
Deadline: September 30

AACR Award for Outstanding Achievement in Cancer Research
Deadline: October 1

AACR G.H.A. Clowes Memorial Award
Deadline: October 1

Elsa U. Pardee Foundation
Deadline: October 1; February 1; June 1

Limited Submission: Blavatnik Awards for Young Scientists
CWRU LOI Deadline: October 6
External Deadline: November 25

American Brain Tumor Association Discovery Grant Funding Program
Deadline: October 8

Pancreatic Cancer Action Network-AACR Research Acceleration Network (RAN) Grant
LOI Deadline: October 8

AACR Richard and Hinda Rosenthal Memorial Award
Deadline: October 8

AACR Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
Deadline: October 8

AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship
Deadline: October 15

AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship
Deadline: October 15

AACR Award for Outstanding Achievement in Chemistry in Cancer Research
Deadline: October 15

American Cancer Society RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families
Application Deadline: October 15

American Cancer Society RFA: The Role of Health Policy and Health Insurance in Improving Access to and Performance of Cancer Prevention, Early Detection, and Treatment Services
Deadline: October 15

American Cancer Society RFA: Pilot and Exploratory Studies Using Community-Based Participatory Research (CBPR) to Achieve Cancer Health Equity
Deadline: October 15

American Cancer Society Research Scholar Grants
Deadline: October 15

American Cancer Society Postdoctoral Fellowships
Deadline: October 15

American Cancer Society Mentored Research Scholar Grant
Deadline: October 15

American Skin Association Research Scholar Awards
Deadline: October 18

American Skin Association Research Scholar Awards for Melanoma/Non-Melanoma Skin Cancer
Deadline: October 18

American Skin Association Research Grants
Deadline: October 18

American Skin Association Medical Student Grants Targeting Melanoma and Skin Cancer
Deadline: October 18

DoD BCRP Breakthrough Award Funding Level 3 and 4
Pre-Application (Preproposal) Deadline: October 22
Invited Application Deadline: January 29, 2015

CTSC KL2 Training Program
Deadline: October 27

Doris Duke Clinical Scientist Development Award
Deadline: October 31

Center for Cancer Research Clinical Investigator Development Program
Deadline: October 31

Worldwide Cancer Research
Deadline: October 31; April 24, 2015

Cancer Research Institute Clinic and Laboratory Integration Program (CLIP) Grants
Deadline: November 1

5th Annual DeGregorio Foundation Award for Cancers of the Esophagus and Stomach
Deadline: November 3

Free to Breathe
Deadline: November 7

Melanoma Research Alliance Young Investigator Award (including Dermatology Young Investigators), Established Investigator Award (including BMS-MRA Established Investigators), and Pilot Award (including SITC-MRA Pilot Award)
Deadline: November 11

Carcinogenesis SS Graduate Student Award/Dharm V. Singh Carcinogenesis Endowment Award
Deadline: November 16

Melanoma Research Alliance Academic-Industry Partnership Award (for Established Investigators and Teams) and BMS-MRA Team Science Award
Deadline: November 21

Friends For An Earlier Breast Cancer Test®
Deadline: December 1

Audrey Meyer Mars International Fellowship in Clinical Oncology
Deadline: December 1

DoD BCRP Breakthrough Award Funding Level 1 and 2
Pre-Application/LOI Deadline: December 3
Application Deadline: December 17

Worldwide Cancer Research
Deadline: October 31, 2014; April 24, 2015

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

Support of Multi-investigator Initiatives in the Case CCC
Deadline: Open

Collaborative Activity Awards
Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Notice of Availability of Frequently Asked Questions (FAQs) and Updated Address for Paper-Based Submissions for PA-14-320 (NOT-OD-14-132)

Notice to Emphasize the Requirement for Additional Educational Information under PA-14-150 "Ruth L. Kirschstein National Research Service Award (NSRA) Individual Predoctoral MD/PhD or Other Dual-Doctoral Degree Fellowship (F30)" (NOT-OD-14-133)

Notice to Emphasize the Requirement for Additional Educational Information under PA-14-147 "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)"(NOT-OD-14-134)

Notice to Emphasize the Requirement for Additional Educational Information under PA-14-148 "Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31 – Diversity)"(NOT-OD-14-135)

Notice to Discontinue the Requirement for Additional Educational Information under PA-14-149 "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)"(NOT-OD-14-137)

Review of Grants Information for Fiscal Year 2014 (NOT-OD-14-138)

Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2015 and 2016 (P50)(PAR-14-353)

4D Nucleome Network Organizational Hub (U01)(RFA-RM-14-010)


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to Gillian Irwin at



Mon, Sept 29

Breast Cancer Program Focus Group Meeting
Topic: Therapeutic Targets
4 pm WRB 3-136

Tumor Immunology/Immunotherapy Meeting
4 pm WRB 1-403

Tues, Sept 30

Radiation Oncology Grand Rounds
Tarun Podder, PhD
Associate Professor, Radiation Oncology
Topic: Stereotactic Body Radiation Therapy (SBRT)
8:10 am Lerner Tower, B-151

Cleveland Clinic Seminar
Nathan P. Coussens, PhD
Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health
Topic: ADAP is Critical for SLP76 Microcluster Assembly and Signal Transduction in T cells
11:30 am NE1-205 Cleveland Clinic

Pharmacology Seminar Series
Kristian Baker, PhD
Center for RNA Biology
Topic: TBD
12 pm Wood W331/Webster Conference room

THOR Lecture Series
Masato Mitsuhashi, MD, PhD 
CTO NonoSomiX Inc.
Topic: Assessment of Bone Marrow (BM) Condition without BM Aspiration
1 pm R3-027 Cleveland Clinic

Cancer Biology Seminar Series
Ziqi Zhu, PhD
Research Fellow, Sharifi lab, Cancer Biology
Cleveland Clinic
Topic: Novel Mechanisms of Hormone Therapy Resistance in Prostate Cancer
2 pm NC1-202 Cleveland Clinic

Director of the Office of Cancer Disparities Research Candidate Seminar
Michael Preston, PhD, MPH
Health Services Researcher/Director, Cancer Control Department
University of Arkansas for Medical Sciences
Topic: Cancer Prevention and Control: Aligning Clinical, Community, and Policy Strategies to Eliminate Cancer Disparities
2 pm WRB 2-136

Wed, Oct 1

Hematology and Oncology Division Research Conference
Joseph Baar, MD, PhD 
Associate Professor, Div. of Hem/Onc
Topic: Fellowship Curriculum Series: Early Stage Breast Cancer 
8 am Lerner B-151

Immunology Students Fellows Research in Progress Seminar
Robert Aguliar
Tuohy lab, Immunology
Cleveland Clinic
Topic: Development of a Testicular Cancer Vaccine
Yan Li
Lin lab, Immunology
Cleveland Clinic
Topic: A Strategy to Improve Current MSC-Based Therapies
12 pm in NC1-202 Cleveland Clinic

Thurs, Oct 2

Molecular Biology and Microbiology/ Center for AIDS Research
Lalith Gunawardane
Molecular Biology and Microbiology, Valadkhan lab
Topic: From High Throughput Screens to Molecular Function of lncRNAs: Insights from aging, latency and neurogenesis
Bing Zhang 
Molecular Biology and Microbiology, Valadkhan lab
Topic: An lncRNA as Coordinator of Stress Response Pathways
1 pm Rottman Seminar Room W203

Fri, Oct 3

Taussig Cancer Institute Grand Rounds
Amy Abernethy, MD, PhD
Professor, Medicine
Director, Duke Center for Learning Health Care
Duke Cancer Center
Topic Improving Patient Centered Outcomes at Scale: Improving Health Care Through Data, Technology, Disciplined Analysis, and Action
8 am R3/002-003 Cleveland Clinic

Cellular and Molecular Medicine Seminar Series
Auinash Kalsotra, PhD
Assistant Professor, Biochemistry and Medical Biochemistry
University of Illinois at Urbana-Champaign
Topic: Functional Impact of Post-transcriptional Gene Regulatory Networks
10 am NC1-202 Cleveland Clinic

Mon, Oct 6

Pathology Research Seminar Series
Huiping Liu, MD, PhD
Department of Pathology
Topic: TBD
12 pm 1-413

GMI Seminar
Bin Zhang, PhD
Associate Staff, Genomic Medicine Institute
Cleveland Clinic
Topic: Trafficking COPs in Controlling Collagen Secretion
12:30 pm NE1-205 Cleveland Clinic

Tues, Oct 7

Immunology Research Seminar Series
Robert Maitta, MD, PhD
Department of Pathology
Topic: Alpha-synuclein in Hematopoiesis and Lymphopoiesis, it is Not Just a Parkinson's Pathologic Mediator
12:00 pm Wolstein Research Bldg 1-413

Pharmacology/Chemistry Joint Seminar
Lawrence Que, Jr.
University of Minnesota
Topic: TBD
12 pm Wood W331/Webster Conf. Rm.

Case CCC Clinical Research Retreat 
5-7 pm WRB 1-413
Pre-registration required

Wed, Oct 8

Cancer Imaging Program Meeting/Imaging Center Seminar Series
Andrew Sloan, MD
Associate Professor, Neurological Surgery
Susann Brady-Kalnay, PhD
Professor, Molecular Biology & Microbiology
Topic: Resection and Molecular Imaging of Brain Tumors
12:30 pm Frohring Auditorium - BRB 105

Early Phase Therapeutics Opportunity Meeting
5 pm WRB 2-136

Thurs, Oct 9

Chemistry Special Seminar
John Cadwell, President & CEO FiberCell Systems
Topic: Hollow Fiber Cell Culture: Cell Culture in 3 Dimensions
10:30am - 12:00 pm Clapp Hall 405

Molecular Biology and Microbiology/Center for AIDS Research Seminar
1 pm Rottman Seminar Room W203

Fri, Oct 10

Taussig Cancer Institute Grand Rounds
Ramaswamy Govindan, MD
Washington University
Topic: Genomics of Lung Cancer: Clinical Implications
8 am R3/002-003 Cleveland Clinic

Cancer Center Research in Progress
James W. Jacobberger, PhD
Professor, Div. of General Medical Sciences (Oncology)
Topic: A Pharmacodynamic Assay For Azacytidine /Decitabine Therapy
4 pm WRB 3-136



Case CCC Calendar

LRI Calendar


ASTRO Review
November 15, 2014
Crowne Plaza, Independence, OH

14th Annual Multidisciplinary Genitourinary Oncology Course
November 20, 2014
InterContinental Hotel & Bank of America Conference Center


Society for Integrative Oncology
October 26-28, 2014
Houston, Texas