MESSAGE FROM THE DIRECTOR
Stan Gerson, MD
Director, Case CCC
Cancer Center Seminar Series 2014-2015
The Cancer Center Seminar Series for the academic year kicks off at noon this Friday, September 5, in Frohring Auditorium (BRB 105), and will feature a presentation by Anant Madabhushi, PhD.
In the short time since his arrival, Anant has forged remarkable collaborative projects around the exciting technology of complex imaging assessments of tumors. Starting with histologic sections and combining efforts with visual imaging, gene expression and radiographic imaging, he is able to construct much more powerful assessments of tumors and to link these to invasiveness, prognosis and stage.
Please don't miss the talk –you need to see it to appreciate the technology and its potential!
CASE CCC IN THE NEWS
In Sickness and in Health
NY Times - Aug 28, 2014
Mikkael Sekeres, MD, Director of the leukemia program at the Cleveland Clinic.
RESEARCH HIGHLIGHTS/MEMBER NEWS
Cancer Center Members Daly and Stange Recognized as Distinguished University Professors
Cancer Center members Barbara Daly, PhD, MSN, FAANand Kurt Stange, MD, PhD were recognized by CWRU as Distinguished University Professors - the university's highest faculty honor - at the Fall Convocation last week.
Dr. Barbara Daly is the Gertrude Oliva Perkins Professor of Oncology Nursing at the Frances Payne Bolton School of Nursing, and Director of Clinical Ethics at University Hospitals Case Medical Center. Read more about her accomplishments here.
Dr. Kurt Stange is the Gertrude Donnelly Hess, MD Professor of Oncology Research and Professor of Family Medicine, Epidemiology & Biostatistics, Oncology and Sociology. Read more about his accomplishments here.
Madabhushi Awarded Two-year NIH Grant on Predicting Aggressive Head & Neck Cancers from Digital Pathology
Anant Madabhushi, PhD, Professor of Biomedical Engineering and Director of the Center for Computational Imaging and Personalized Diagnostics, has been awarded an R21 grant from the National Cancer Institute for his project, Histologic Image-based Aggressiveness Prediction in p16+ Oropharyngeal Carcinoma. The focus of this two-year $386,000 project will be to develop computerized image analysis tools for identifying patterns connecting to aggressive behavior from digitized tissue slides images of p16+.
MARK YOUR CALENDARS
Fall 2014 Case CCC Clinical Research Retreat
The Case CCC will be holding a Clinical Research Retreat on October 7 in the Wolstein Research Building. A reception will be held from 5-5:30 pm, followed by presentations from 5:30-7 pm.
The agenda will focus on the theme of Immunotherapy:
James Finke, PhD: Strategies to Reduce Immune Suppression as a Means to Improve Immunotherapy: A laboratory perspective
Joseph Baar, MD: Recent Advances in the Immunotherapy of Cancer
Shaveta Vinayak, MD: Tumor Infiltrating Lymphocytes Predict for Response to Therapy in Triple-negative Breast Cancer
Mitchell Machtay, MD: National Clinical Trials Network/Cooperative Groups (NCTN) Update
2014 Adolescent and Young Adult Cancers Symposium
The 2014 Adolescent and Young Adult (AYA) Cancers Symposium will be held October 30-31, 2014 in the Wolstein Research Building. The focus of this two-day symposium will be on advancing AYA-related research, increasing federal funding, and exploration of scientific, clinical and psychological considerations in the AYA population.
Program highlights include a keynote address by Clifton Leaf, Deputy Managing Editor of Fortune Magazine and author of The Truth in Small Doses Why We're Losing the War on Cancer – And How to Win It.
Registration and program details soon to follow! For additional information or questions, please emailAYASYM2014@UHhospitals.org.
Limited Submission: NSF Partnerships for International Research and Education (PIRE)
Partnerships for International Research and Education (PIRE)is an NSF-wide program that supports international activities across all NSF supported disciplines. The primary goal of PIRE is to support high quality projects in which advances in research and education could not occur without international collaboration. PIRE seeks to catalyze a higher level of international engagement in the U.S. science and engineering community.
International partnerships are essential to addressing critical science and engineering problems. In the global context, U.S. researchers and educators must be able to operate effectively in teams with partners from different national environments and cultural backgrounds. PIRE promotes excellence in science and engineering through international collaboration and facilitates development of a diverse, globally-engaged, U.S. science and engineering workforce. This PIRE competition will be open to all areas of science and engineering research which are supported by the NSF.
A single organization may submit one preliminary proposal as the lead institution. Full proposals will be accepted by invitation only.
Internal LOI Deadline: September 19
External Deadline: October 21
American Cancer Society
The American Cancer Society is accepting applications for the following opportunities, all with a deadline of October 15:
RFA: The Role of Health Policy and Health Insurance in Improving Access to and Performance of Cancer Prevention, Early Detection, and Treatment Services: call for research that evaluates the impact of the many changes now occurring in the healthcare system with a particular focus on cancer prevention, control, and treatment. Efforts focusing on improving access to care may also impact inequities that contribute to health disparities. New health public policy initiatives such as the new federal and state marketplaces that have expanded insurance coverage, as well as Medicaid expansion in some states, create natural experiments ripe for evaluation. Research to be funded by this RFA should focus on the changes in national, state, and/or local policy and the response to these changes by healthcare systems, insurers, payers, communities, practices, and patients.
RFA: Pilot and Exploratory Studies Using Community-Based Participatory Research (CBPR) to Achieve Cancer Health Equity: The purpose of this RFA is to stimulate research on effective interventions to reduce cancer health disparities (at any stage of the cancer continuum) and achieve cancer health equity using community-based participatory research (CBPR). This request for applications (RFA) aligns with the American Cancer Society's commitment to reducing disparities in the cancer burden among population groups and to achieving health equity through its programmatic, research and advocacy strategies.
Studies funded by this RFA must:
- Focus on addressing cancer health disparities and other strategies to contribute to achieving health equity
- Use CBPR as the research method or propose strategies to generate preliminary data critical to the development of a CBPR research study
- Demonstrate clear evidence of how this pilot data will be used to develop a larger independently funded study (e.g., NIH R21 or RO1, Patient Centered Outcomes Research Institute (PCORI) grant or ACS Research Scholar Grant).
Research Scholar Grants support investigator-initiated projects across the cancer research continuum. Awards are for up to four years and for up to $165,000 per year (direct costs), plus 20% allowable indirect costs. Independent investigators in the first six years of an independent research career or faculty appointment are eligible to apply. There are exceptions to this, however. Exceptions: 1) RSG applicants to the Cancer Control and Prevention Research Program ONLY may be at any career stage provided the focus of their project is either: a) health policy/health services research or b) cancer disparity reduction; 2) Psychosocial or behavioral studies that are population based (5 years of funding are permitted) where a budget of $400,000 per year (direct costs), plus 20% allowable indirect costs is permitted.
Postdoctoral Fellowships support the training of researchers who have received a doctoral degree to provide initial funding leading to an independent career in cancer research (including basic, preclinical, clinical, cancer control, psychosocial, behavioral, epidemiology, health services and health policy research).
Mentored Research Scholar Grant support for mentored research and training to full-time junior faculty, typically within the initial four years of their first independent appointment. The goal is for these beginning investigators to become independent researchers as either clinician scientists or cancer control and prevention researchers.
American Skin Association
The American Skin Association is accepting applications for the following opportunities, all with a deadline of October 18.*A Chair can endorse only one Scholar Award (either category) and one research grant each year.
Research Scholar Awards support basic science and clinical research by investigators in the early phases of their careers, working at the level of instructor through associate professor in the field of dermatology or cutaneous biology. The aim of the program is to provide bridge support for young investigators. Special consideration will be given to individuals without significant prior support.
Research Scholar Awards for Melanoma/Non-Melanoma Skin Cancer fosters the career development of a young investigator working at the level of instructor through associate professor in the field of dermatology or cutaneous biology. The aim of the program is to provide bridge support for young investigators. Special consideration will be given to individuals without significant prior support.
Research Grants underwrite new and ongoing clinical investigations in five areas – melanoma/skin cancer, psoriasis/inflammatory diseases, vitiligo/pigment cell biology, childhood diseases, and quality of life/health services/outcome studies. There is no age requirement. However, applicants without prior funding, who are in a formative stage of their career, or who are undergoing a mid-career research change will be given preference.
Medical Student Grants Targeting Melanoma and Skin Cancer supports medical students to do research in the area of melanoma and non-melanoma skin cancer.
HELP US HELP YOU!
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