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July 21, 2014


Stan Gerson, MD
Director, Case CCC 

Case CCC Annual Scientific Retreat- Student, Fellow & Trainee Poster Session

I never fail to be impressed with the level of science that is demonstrated by our Center. I am especially proud to say that statement holds true for the students, fellows and trainees that presented posters at the Cancer Center Annual Scientific Retreat earlier this month.

We had a record number of posters this year; winners and their mentors should be especially pleased to be recognized for their work given the tough competition.

I would also like to thank the judges who gave their time at the end of a long day to listen to the presentations and judge the posters. Your expertise was appreciated!

Poster Session Winners:

Poster Session Winners

Program 1: Cancer Genetics
Babal Jha 
Mentor: Robert Silverman

Program 2: Basic Sciences
Raffaella Spina
Mentor: Eli E. Bar

Program 3: Breast Cancer (Devel Program)
Mary Doherty
Mentor: Mark Jackson

Program 4: GU Malignancies
Danica Wiredja
Mentor: Mark Chance/Goutham Narla

Program 5: Hematopoietic Disorders
Praveena Thiagarajan
Mentor: Justin Lathia/Ofer Reizes

Program 6: Developmental Therapeutics
Anil Belur Nagaraj
Mentor: Analisa DiFeo

Program 7: Cancer Imaging
Debasis Pore
Mentor: Neetu Gupta


Researchers Find Support Team Can Help Caregivers Manage End-of-life Treatment, Decisions
Case Daily - July 21, 2014
Many caregivers of terminal cancer patients suffer depression and report regret and guilt from feeling they could have done more to eliminate side effects and relieve the pain. So researchers from the Frances Payne Bolton School of Nursing at Case Western Reserve University devised and tested an intervention that quickly integrates a cancer support team to guide caregivers and their patients through difficult end-of-life treatment and decisions...In the past, many of those conversations started too late "days or weeks before the patient died, said Sara Douglas, associate professor in the School of Nursing and lead author. "We owe it to the patients and caregivers to start earlier and think the choices through," said Douglas, who conducted the research with CWRU colleague and principal investigator, Barbara Daly, the Gertrude Perkins Oliva Professor in Oncology Nursing and member of the Case Comprehensive Cancer Center.

Survivors, Cyclers, Supporters Gather in Downtown Cleveland for VeloSano Ride
The Plain Dealer - July 19, 2014
The early hour and the gloomy weather didn't stop riders and supporters from being ready to go Saturday morning for the first ever VeloSano Cleveland bicycle ride. Riders lined up on St. Clair Avenue near the Global Center for Health Innovation to participate in the event. Over 800 riders were signed up as of Thursday evening. VeloSano had raised more than $1.5 million by the beginning of the ride, according to the event's website. All the money raised from the ride will go towards cancer research at the Cleveland Clinic.

Chemoprevention and Colon Cancer: An interview with Dr. John Letterio, Case Western Reserve University School of Medicine
News Medical - July 16, 2014
Interview with Dr. John Letterio, Director of the Angie Fowler Adolescent & Young Adult Cancer Institute and Chief of Pediatric Hematology/Oncology at University Hospitals Case Medical Center and Case Western Reserve University in Cleveland, Ohio. Dr. Letterio is also a member of the Case Comprehensive Cancer Center.


Support of Multi-investigator Initiatives in the Case CCC

The Case CCC will provide two modes of support to new research teams that plan to submit large multi-investigator grant applications (usually non-R support mechanisms):

  • Administrative support and funding for travel are available to encourage team member meetings and meetings with external advisors.

  • Pilot project funding for research teams with an established track record of collaborative research is available to support key research initiatives that are necessary to generate competitive multi-investigator proposals.

Requests are competitive. The research team must demonstrate the active engagement of members, clearly articulate the significance and innovation of the project, and provide a roadmap for acquisition of external funding. Advocacy and support of the specific program leadersinteracting with the team is required.

Discussion with Dr. Ruth Keri, Associate Director for Basic Research (, is strongly encouraged before developing an application. Complete description and instructions are available on the Cancer Center website.
Deadline: Open

Greenwall Foundation

The Greenwall Foundation will fund a bioethics grants program, Making a Difference in Real-World Bioethics Dilemmas, to support research to help resolve an important emerging or unanswered bioethics problem in clinical care, biomedical research, public health practice, or public policy. Under this RFP, the Foundation will fund five types of bioethics research grants:

  • Mentored projects

  • Senior collaborations

  • Normative analyses of implications of empirical research conducted with other funding

  • Empirical projects

  • Empirical studies of attitudes of clinical trials participants to sharing clinical trials data, which is described in greater depth below.

Applicants are strongly encouraged to submit letters of intent earlier than the deadline to allow time to respond to feedback from reviewers, if invited to submit a full application.
LOI Deadline: August 1

American Association for the Advancement of Science

The American Association for the Advancement of Science (AAAS) has announced a new grant opportunity, the Marion Milligan Mason Award for Women in the Chemical Sciences. The objective of the Mason Award is to kick-start the research career of promising future senior investigators in the chemical sciences. The Marion Milligan Mason Fund will provide three grants of $50,000 every other year to women researchers engaged in basic research in the chemical sciences. Awards are for women who are starting their academic research careers. In addition to research funding, the program will provide leadership development and mentoring opportunities.

Applicants must have a "full-time" career-track appointment. More than one applicant from the same institution can apply for this award, provided that each application is scientifically distinct. Please contact Sandie Moster at if you plan to pursue this opportunity. 
Deadline: September 15

Prostate Cancer Foundation Global Treatment Sciences Challenge Award for Lethal Prostate Cancer

The Prostate Cancer Foundation (PCF) is pleased to announce an RFA for lethal prostate cancer. Approximately 5-10 GTSN Challenge Awards will be funded depending on level of innovation in applications received. High-risk, first-in-field and currently unfunded projects are most desired. PCF Challenge Awards support large-scale team science research projects concerning lethal prostate cancer over a duration of 2-3 years. Projects must focus on funding treatment sciences: investigations to support the correlative research around either clinical trials of novel agents or strategies or standard of care. One emphasis is on developing or validating biomarkers that guide therapy in patients or further our understanding of the mechanism by which therapies work. While the emphasis is on research in humans, the actual trials or treatments themselves will not be supported. Human samples are highly preferred although at times model systems might be required to complement our understanding.
Deadline: September 22



SOM Institutional Scientific Core Facility Retreat

The Second Annual SOM Institutional Scientific Core Facility Retreat is scheduled for August 25. Retreat participation is by invitation only and is primarily for Core Facility Directors and Managers, as well as Administrative/Clerical Staff. However, there will be limited additional seating available. If you would like to attend, please follow this link to request an invitation.

NCRM Cancer Stem Cell Conference

The first CWRU: National Center for Regenerative Medicine Cancer Stem Cell Conference will be held in Cleveland,August 17-20, 2014. This conference is guaranteed to have incredible research from a variety of backgrounds in the Cancer Stem Cell field, and will feature keynote speakers from over 25 different institutions from around the world.

Attendees are invited to submit abstracts of original investigation for consideration in the poster session and possible short talk podium presentations. Deadline to submit abstracts is July 27.


DoD Prostate Cancer Research Program Prostate Cancer Pathology Resource Network Award
Pre-Application Deadline: July 23
Application Deadline: October 29

DoD Prostate Cancer Research Program Health Disparity Research Award
Pre-Application Deadline: July 23
Application Deadline: September 24

DoD Prostate Cancer Research Program Laboratory–Clinical Transition Award
Pre-Application Deadline: July 23
Application Deadline: October 29

DoD Prostate Cancer Research Program Population Science Impact Award
Pre-Application Deadline: July 23
Application Deadline: October 29

DoD Prostate Cancer Research Program Clinical Exploration Award
Pre-Application Deadline: July 23
Application Deadline: October 29

DoD Lung Cancer Research Program Concept Award
LOI Deadline: July 29
Application Deadline: August 12

Linda K. Arena Endowed Scholarship Award For Lung Cancer Education 
Deadline: July 28

ACSR Young Investigator Pilot Award
Deadline: August 1

American Cancer Society Clinical Research Professor
LOI Deadline: August 1
Application Deadline: October 15

Mesothelioma Applied Research Foundation Research Grant Program
Deadline: August 8

Uniting Against Lung Cancer
Deadline: August 13

Damon Runyon Cancer Research Foundation Fellowship Awards
Deadline: August 15

Harrington Prize for Innovation in Medicine
Deadline: August 15

DoD Breast Cancer Research Program Breast Cancer Innovator Award
Deadline: August 15

DoD Breast Cancer Research Program Era of Hope Scholar Award
Deadline: August 15

Harrington Prize for Innovation in Medicine
Deadline: August 15

American Society of Cytopathology Foundation Patient Advocacy Grant
Deadline: August 15

DoD Prostate Cancer Research Program Physician Research Training Award
Pre-Application Deadline: August 27
Confidential Letters of Recommendation: September 10
Application Deadline: September 10

DoD Prostate Cancer Research Program Collaborative Undergraduate Historically Black Colleges and Universities (HBCU) Student Summer Training Program Award
Pre-Application Deadline: August 27
Application Deadline: September 10

DoD Prostate Cancer Research Program Postdoctoral Training Award
Pre-Application Deadline: August 27
Confidential Letters of Recommendation: September 10
Application Deadline: September 10

DoD Bone Marrow Failure Idea Development Award 
Deadline: August 28

R. Robert & Sally Funderburg Research Award in Gastric Cancer
Deadline: August 29

Center for Global Health Short-Term Scientist Exchange Program
Deadline: September 1; December 1; March 1; June 1

Lymphoma Research Foundation Adolescent/Young Adult Cooperative Group Correlative Studies Grant
Deadline: September 3

Lymphoma Research Foundation Clinical Investigator Career Development Grant Program
Deadline: September 3

Lymphoma Research Foundation Lymphoma Clinical Research Mentoring Program (LCRMP)
Deadline: September 3

Lymphoma Research Foundation Postdoctoral Fellowship Grant 
Deadline: September 3

2014 AICR Conference Scholarship
Deadline: September 5

Elsa U. Pardee Foundation
Deadline: October 1; February 1; June 1

CTSC KL2 Training Program
Deadline: October 27

Center for Cancer Research Clinical Investigator Development Program
Deadline: October 31

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

Pilot Grants: Planning for Multi-Investigator Proposals
Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)(PA-12-149)

Pilot Centers for Precision Disease Modeling (U54)(PAR-14-280)

High Throughput Screening (HTS) to Discover Chemical Probes (R21)(PAR-14-283)

High Throughput Screening (HTS) to Discover Chemical Probes (R01)(PAR-14-284)

Innovative Research in Cancer Nanotechnology (IRCN) (U01)(PAR-14-285)

U.S.-China Program for Research Toward a Cure for HIV/AIDS (R01)(RFA-AI-14-057)

Centers of Cancer Nanotechnology Excellence (CCNEs)(U54)(RFA-CA-14-013)

Neuroscience Information Framework (U24)(RFA-DA-15-009)

The Electronic Medical Records and Genomics (eMERGE) Network, Phase III Coordinating Center (U01)(RFA-HG-14-026)

The Electronic Medical Records and Genomics (eMERGE) Network, Phase III Central Sequencing and Genotyping Facility (U01)(RFA-HG-14-027)


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to Gillian Irwin at

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Tues, July 22

Pharmacology Special Seminar
Sander Kersten, PhD
Institute of Human Nutrition 
Wageningen University, The Netherlands
Topic: Regulation of Metabolism by PPARs
10 am SOM W331

Wed, July 23

Hematology and Oncology Division Research Conference Curriculum Series
Guilherme H. Oliveira, MD
Associate Professor, Medicine
Director, Onco-Cardiology Program
Topic: OncoCardiology
8 am Lerner Tower B-151

Academic Drug Development Seminar
Zhenghe John Wang, PhD
Associate Professor, Genetics
Topic: Targeting Mutant PIK3CA/p110 Alpha for Cancer Therapy
4 pm Global Cardiovascular Innovation Center

Fri, July 25

Hematology/Oncology Fellows
Howard Meyerson, MD
Associate Professor, Pathology
Topic: Hematologic Emergencies: Pathology Review
8 am Breen Conf Rm.

Tues, July 29

Cancer Biology Faculty Candidate
Yusuke Shiozawa, MD, PhD
Research Investigator, Periodontics and Oral Medicine
University of Michigan
Topic: Bone as a Target: Solving the Mystery of Prostate Cancer Metastasis
11 am NC1-202 Cleveland Clinic

Wed, July 30

Hematology and Oncology Division Research Conference Curriculum Series
Cheng Chee, MD
Assistant Professor, Div. of Hem/Onc
Topic: Early Stage Colorectal Cancer
8 am Lerner Tower B-151

Cancer Center Faculty Candidate Seminar
Wenge Zhu, PhD
Assistant Professor, Biochemistry and Molecular Biology
George Washington University Medical Center
Topic: Maintenance Of Genomic Stability In Human Cell
9 am WRB 3-136

Thurs, July 31

Leaders in AIDS Research
Andrew Rice, PhD
Professor, Molecular Virology & Microbiology
Baylor College of Medicine
Topic: HIV Gene Regulation and Latency
1 pm SOM W203

Mon, August 4

Cancer Biology Staff Candidate
James Jackson, PhD
Instructor, Genetics
University of Texas M.D. Anderson Cancer Center 
Topic: Mutant p53: Breast cancer's vulnerability?
1:30 pm NC1-202 Cleveland Clinic

Case CCC Calendar

LRI Calendar


Cancer Stem Cell Conference
August 17-20, 2014
Cleveland, OH


American Society for Matrix Biology Biennial Meeting: Integrating Extracellular Matrix and Cellular Networks in Biology and Medicine
October 12-15
Cleveland, OH

Society for Integrative Oncology
October 26-28, 2014
Houston, Texas