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April 21, 2014

MESSAGE FROM THE DIRECTOR

Stan Gerson, MD
Director, Case CCC 

Catchment and Community Outreach Linked to Cancer Research and Education at Case CCC

As our members know, we have pursued our programmatic efforts in community outreach and research through research projects, hospital-based community engagements, and advocacy.

The Cancer Center Community Advisory Board, now in its third year, meets every 2-3 months to pursue and develop community engagement efforts. This group has taken on increased efforts in the following areas:

  • Education about cancer screening, particularly for lung, breast and prostate cancers, where we recognize a higher death rate within the City of Cleveland.
  • A brochure about cancer clinical trials that is reader-friendly and informative
  • Physician and staff training in issues of cross-cultural sensitivity, or cultural competency

As a result of these meetings, a few weeks ago, Brian Bolwell and I met with Cleveland Mayor Frank Jackson to discuss these initiatives and seek his support and advocacy. He was very supportive and encouraged our involvement in a number of Cleveland wide initiatives, including:

  • More public service announcements and education efforts
  • Discussions with City Council about our efforts in screening and healthy life style
  • Discussions with the city schools about the findings of the use of small cigars
  • Links to the Healthy Cleveland initiative that have undertaken projects in reducing obesity, improving healthy lifestyles, and improving access to medical facilities

While we recognize our need to focus on hypotheses and data so we can impact cancer by using our research discoveries to direct prevention, early detection and treatment, the first aspect of dissemination involves community engagement.

We will be encouraging Cancer Center members, and our academic hospital centers (Cleveland Clinic, University Hospitals and MetroHealth) to participate with us as we increase efforts to link with the City of Cleveland through its health commissioner, Council and school system. We will also continue our community efforts with churches, the CMHA, community health centers, and The Gathering Place to support community efforts to promote specific targets that will improve prevention of cancer through vaccination (HPV), decreased smoking rates, and weight reduction; improved rates of cancer screening, particularly for those cancers in which we observe an excess dearth rate – lung, breast and prostate cancers, and improved participation in clinical research. In later notes from me, specific initiatives will be identified and your involvement will be encouraged.

As the mayor put it, it does much more good to help change the culture of Clevelanders towards better health than any single event can possibly achieve. That sounds like both an opportunity and a challenge for our Cancer Center.

Call for Abstracts: Society for Integrative Oncology

The Society for Integrative Oncology (SIO) has opened its Call for Abstracts for SIO's 11th International Conference, to be held October 26-28, 2014 in Houston, Texas. Abstracts representing the broad spectrum of integrative oncology, integrative cancer research (basic, clinical, health care utilization, cost effectiveness, program and best practice guideline development), and clinical care are welcomed through April 30. In keeping with this year's conference theme of Personalized Integrative Oncology: Targeted Approaches for Optimal Outcome, individuals submitting abstracts are encouraged to consider the targeted and personalized approaches of their work and its relevance to integrative cancer care.

Please review this opportunity to participate in the upcoming SIO conference. This year, the SIO will take place in Houston, near MD Anderson, Baylor and Texas Childrens. While the effort has coalesced alternative and integrative oncology elements, it does provide a very interesting perspective on supportive oncology, the elements of pain management and palliative care, the use of all aspects of supportive oncology, music, massage, nutrition, and move innovative aspects of genomics and outcomes research. The Moss Foundation has offered to support travel and attendance costs which I would like to suggest be prioritized to those members of the Cancer Center who submit an abstract. If you do, please let me know.


CASE CCC IN THE NEWS

Crain's Business Cleveland is running a series of articles on "The Business of Cancer":

NE Ohio hospitals use localized treatment to build care network
Crain's Business Cleveland - Apr 21, 2014
With University Hospitals and the Cleveland Clinic, Northeast Ohio is fortunate to have two nationally ranked cancer programs headquartered less than two miles apart. Both enterprises – and to a lesser extent, their smaller counterparts in Northeast Ohio – have steadily increased their cancer-related offerings in the region and show few signs of slowing their suburban conquest..."It's a very competitive field in part because it's such an important part of the health care field," said Dr. Brian Bolwell, chair of the Clinic's Taussig Cancer Institute and member of the Case Comprehensive Cancer Center...Dr. Nathan Levitan, president of UH Seidman Cancer and member of the Center Case Comprehensive Cancer Center, said cancer care has historically been a "high-margin" type of health care. But as the economics of health care have changed, those profit margins have slimmed and hospitals have tried to provide higher quality care in lower-cost settings.

A view of cancer care from the front lines
Crain's Business Cleveland - Apr 21, 2014
Interviews with Drs. Neal Meropol, Chief, Division of Hematology and Oncology, CWRU and University Hospitals Case Medical Center and Associate Director for Clinical Research at the Case Comprehensive Cancer Center; John Suh, Chairman, Department of Radiation Oncology, Cleveland Clinic and Case Comprehensive Cancer Center member; Natalie Joseph, Medical director and surgical oncologist, MetroHealth Breast Center;

Firms ramping up efforts in cancer space
Crain's Business Cleveland - Apr 21, 2014
Nowadays, institutions such as the Cleveland Clinic and Case Western Reserve University are more willing to form startup companies tasked with turning cancer drugs – and other pharmaceuticals – into products, according to Glen Gaughan, CEO-in-residence at BioEnterprise Corp., a Cleveland nonprofit that assists local health care companies. And, that shift could help the region play a larger role in developing new cancer technologies...Cancer Center member Vincent Tuohy is learning how hard it is to commercialize a cancer drug. His team at the Clinic has been trying to create that vaccine since 2002. The team received $1.3 million in federal grants about four years ago, and in 2010 it published research suggesting that the vaccine could prevent mice from developing breast tumors.

Doctors take personal approach with disease
Crain's Business Cleveland - Apr 21, 2014
Take new research at University Hospitals Seidman Cancer Center spearheaded by Dr. Lyndsay Harris, medical director of the center's Breast Cancer Program and co-Leader of the Case Comprehensive Cancer Center Breast Cancer Program. Her innovative trial recruits patients to further her groundbreaking research that uses deep genome sequencing to reveal changes in breast cancer tumors after just one dose of preoperative therapy...Go to the Cleveland Clinic and you'll find Dr. Davendra Sohal, staff physician in the Department of Solid Tumor Oncology at the Taussig Cancer Institute and Case Comprehensive Cancer Center member, studying the feasibility and clinical impact of targeted genomic sequencing on patients with certain tumors that have a poor prognosis or limited treatment options. He expects to explore with 250 patients personalized oncology in a well-defined, systematic manner...Diagnosed with Hodgkin's lymphoma at age 24, Michael Kattan, chairman of the Department of Quantitative Health Sciences in Cleveland Clinic's Lerner Research Institute and member of the Case Comprehensive Cancer Center , was in graduate school studying financial risk calculators. He found the staging process of the cancer in his lymph nodes to be crude and highly generalized not taking into account personal characteristics as basic as age and overall health and overlooking specific test results.


FUNDING OPPORTUNITIES

Limited Submission: National Science Foundation Scalable Nano Manufacturing

The National Science Foundation (NSF) announces a fourth year of a program on collaborative research and education in the area of scalable nanomanufacturing, including the long-term societal implications of the large scale implementation of nanomanufacturing innovations. This program is in response to and is a component of the National Nanotechnology Initiative Signature Initiative: Sustainable Nanomanufacturing - Creating the Industries of the Future. Although many nanofabrication techniques have demonstrated the ability to fabricate small quantities of nanomaterials, nanostructures and nanodevices for characterization and evaluation purposes, the emphasis of the scalable nanomanufacturing program is on research to overcome the key scientific and technological barriers that prevent the production of useful nanomaterials, nanostructures, devices and systems at an industrially relevant scale, reliably, and at low cost and within environmental, health and safety guidelines.
CWRU LOI Deadline: April 21
NSF Deadline: June 16

AACR Scientific Achievement Awards

The AACR is currently accepting nominations for three of its Scientific Achievement Awards recognizing excellence in cancer research.

  • 2014 AACR Outstanding Investigator Award for Breast Cancer Research, funded by Susan G. Komen® for an investigator whose novel and significant work has had or may have a far-reaching impact on the etiology, detection, diagnosis, treatment, or prevention of breast cancer. The recipient of this Award will receive a $10,000 honorarium and present a 25-minute lecture at the annual San Antonio Breast Cancer Symposium.
    Nomination deadline: May 14
  • 2014 AACR Distinguished Lecture on the Science of Cancer Health Disparities, funded by Susan G. Komen®for an investigator whose novel and significant work has had or may have a far-reaching impact on the etiology, detection, diagnosis, treatment or prevention of cancer health disparities. The recipient of this Award will receive a $5,000 honorarium and present a 45-minute lecture at the Seventh Annual AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved.
    Nomination deadline: June 18
  • 2014 AACR Award for Outstanding Achievement in Cancer Prevention Research for a scientist for his or her seminal contributions to the field of cancer prevention which have had a major impact on the field and stimulated new directions in this important area. The recipient of the Award will receive a $5,000 honorarium and present a 50-minute lecture at the 13th Annual AACR International Conference on Frontiers in Cancer Prevention Research.
    Nomination deadline: June 18

DOD Ovarian Cancer Research Program

Applications to the Fiscal Year 2014 Ovarian Cancer Research Program (OCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity.

  • The intent of the OCRP Clinical Translational Leverage Award mechanism is to support leveraging of human-based ovarian cancer resources in translational research. This award supports early-phase, proof-of-principle clinical trials and correlative studies (retrospective and prospective) to investigate high-impact research ideas or unmet needs in ovarian cancer. Preliminary data are required. Funding from the Clinical Translational Leverage Award must support a clinical trial or a correlative study associated with an ongoing or completed clinical trial.
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only): August 27
  • The OCRP Investigator-Initiated Research Award is intended to support studies that will significantly impact ovarian cancer research and/or patient care. Research projects may focus on any phase of research from basic laboratory research through translational research. The rationale for a research idea may be derived from a laboratory discovery, population-based studies, a clinician's first-hand knowledge of patients, or anecdotal data. Applications must include preliminary data that are relevant to ovarian cancer and support the proposed research project.
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only):August 27
  • The Ovarian Cancer Academy Dean and Assistant Dean (Leadership) Award is soliciting applications for an Academy Dean and Assistant Dean to lead the Ovarian Cancer Academy starting no later than October 2015. The Academy Dean and Assistant Dean (referred to as Academy Leadership) must be established ovarian cancer researchers. Designated Mentors on FY14 Ovarian Cancer Academy Early-Career Investigator applications and Designated Mentors of current Ovarian Cancer Academy Early-Career Investigators are eligible to apply for this award. The Academy Leadership must demonstrate a strong record of mentoring and training junior investigators, a commitment to leadership, and the ability to objectively assess the progress of all of the Early-Career Investigators in the Ovarian Cancer Academy.
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only): August 20
  • The OCRP Ovarian Cancer Academy, which was initially created in FY09, is intended to be a unique, interactive virtual academy providing intensive mentoring, national networking, and a peer group for junior faculty. The overarching goal of the Ovarian Cancer Academy is to develop successful, highly productive ovarian cancer researchers in a collaborative research training environment. This FY14 Program Announcement/Funding Opportunity is soliciting additional Early-Career Investigators to join the existing Academy. Applications to this award mechanism must be submitted by the Early-Career Investigator as the Principal Investigator (PI).
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only): August 27
  • The OCRP Pilot Award supports conceptually innovative, high-risk/high-reward research that could ultimately lead to critical discoveries or major advancements that will drive the field of ovarian cancer research forward. The proposed research must demonstrate a clear focus on ovarian cancer (e.g., using tissues, cell lines, datasets, or appropriate animal models, etc.). The proposed research should include a testable hypothesis based on strong scientific rationale and serve as a catalyst to expand or modify current thinking about and/or approaches in ovarian cancer research. Preliminary data are not required, but are allowed. The strength of the application should be based on sound scientific rationale and logical reasoning. Clinical trials will not be supported by this award mechanism.
    Pre-Application Deadline (Required): May 22
    Application Deadline (Invite Only): August 20

DOD Lung Cancer Research Program

Applications to the Fiscal Year 2014 Lung Cancer Research Program (LCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity. Submissions from and partnerships with investigators at Military Treatment Facilities, military labs, the Department of Veterans Affairs Medical Centers and research laboratories are strongly encouraged.

  • The LCRP Career Development Award supports early-career, independent investigators to conduct impactful research under the mentorship of an experienced lung cancer researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of lung cancer research. This award is intended to support impactful research projects with an emphasis on discovery.
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only): September 17
  • The LCRP Clinical Exploration Award (CEA) mechanism supports early-phase, proof-of-principle clinical trials and correlative studies to investigate hypothesis-based, innovative interventions that have the potential to resolve current clinical barriers and result in a profound impact on the clinical management of lung cancer. While therapeutic approaches proposed for testing through the CEA must represent novel, hypothesis-based, "outside-the-box" approaches for treating lung cancer, they may include therapies already in clinical use, or undergoing clinical testing, for other diseases, provided that the proposed use for lung cancer would lead to a major advancement for treating the disease.
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only): September 17
  • The LCRP Idea Development Award promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress toward eradicating deaths from lung cancer. The FY14 Idea Development Award mechanism encourages applications from independent investigators in the early stages of their careers (i.e., within 10 years of their first faculty appointment, or equivalent). The New Investigator category is designed to allow applicants early in their faculty appointments to compete for funding separately from established investigators. Applications from New Investigators and Established Investigators will be peer- and programmatically reviewed separately.
    Pre-Application Deadline (Required): June 3
    Application Deadline (Invite Only): September 17

ANNOUNCEMENTS

Join Our Team - Race for the Place

Walk or run with the Case Comprehensive Cancer Center team at the Race for the Place, June 1, 2014. This great event helps The Gathering Place to offer services to anyone touched by cancer, no matter their economic situation. Anyone is welcome to join our team. If you can't make the Race in person, please consider making a donation to support our efforts. Click here to view our team page.


MARK YOUR CALENDARS

CME Event - Screening for Cancer in Women: 2014

Registration is open for Screening for Cancer in Women: 2014Wednesday, May 21 from 8 am - 3:35 pm at the Embassy Suites Hotel in Independence.

This conference will feature speakers from health centers across Northeast Ohio working together to fight cancer, who will offer expert insight, updates, and advice on screening for cancer in women.

KEYNOTE ADDRESS: Cancer Screening and Prevention in High-Risk Women
Allison Kurian, MD, MSc, Assistant Professor, Medicine (Oncology) and Health Research & Policy, Associate Director, Stanford Program in Clinical Cancer Genetics, Physician Leader, Stanford Women’s Cancer Genetics Clinic, Stanford University

PRESENTERS AND PANELISTS
Stan Gerson, MD: Welcome
Holly Marshall, MD: Breast Cancer Screening
Jeff Marks, MD: Update on Colon Cancer Screening in Women
Brian Bolwell, MD: Affordable Care Act
Allison Vidimos, MD: Skin Cancer Screening in Women
Phyllis Nsiah-Kumi, MD, MPH: Cancer Disparities
Allison Kurian, MD, MSc; Andrea Sikon, MD, FACP; Shaveta Vinayak, MD; Cindy Zelis, MD: Panel Discussion
Charles Lau, MD, MBA: Lung Screening
Kim Gecsi, MD: Gynecologic Cancer Screening
Paula Silverman, MD: Closing Remarks

PLANNING COMMITTEE
Donna Plecha, MD, Activity Director
Paula Silverman, MD, Chair
Lyndsay N. Harris, MD
Halle Moore, MD

Primary care physicians, hematologists, medical oncologists, and nurses should attend this course.

CME credit will be offered. Visit the conference website for more details and registration information.

NCRM Cancer Stem Cell Conference

The first CWRU: National Center for Regenerative Medicine Cancer Stem Cell Conference will be held in Cleveland, August 17-20, 2014. This conference is guaranteed to have incredible research from a variety of backgrounds in the Cancer Stem Cell field, and will feature keynote speakers from over 25 different institutions from around the world. Register today to connect with an international community of researchers and their work.

PREVIOUSLY ANNOUNCED OPPORTUNITIES

Brian Werbel Memorial Fund Summer Cancer Research Fellowships
Deadline: April 25

Prostate Cancer Foundation 2014 Movember-PCF Global Treatment Sciences (GTSN) Challenge Award For Metastatic Prostate Cancer
Deadline: April 30

Limited Submission: National Science Foundation Research Traineeship Program
CWRU LOI Deadline: May 1
NSF Deadline: June 24

Harrington Scholar-Innovator Award
LOI Deadline: May 2
Invited Application Deadline: August 1

American Society of Hematology (ASH) Scholar Awards
LOI Deadline: May 7
Invited Application Deadline: August 1

GlaxoSmithKline Discovery Fast Track Challenge
Deadline: May 16

L'Oréal USA For Women in Science Fellowship Program
Deadline: May 19

DoD BCRP Breast Cancer Breakthrough Award Levels 1 and 2 
Deadline: May 28

DoD BCRP Breast Cancer Breakthrough Award Levels 3 and 4
Deadline: May 28

Doctors Cancer Foundation
Deadline: May 31

HHMI Investigator Program National Competition
Deadline: June 3

Vilcek Prizes For Creative Promise in Biomedical Science
Deadline: June 10

Lung Cancer Research Foundation
Deadline: June 16

Stand Up To Cancer (SU2C)-Cancer Research UK Translational Research Fellowship
Deadline: July 28

Damon Runyon Fellowship Award
Deadline: August 15

DoD BCRP Breast Cancer Innovator Award
Deadline: August 15

DoD BCRP Breast Cancer Era of Hope Scholar Award
Deadline: August 15

DoD BMFRP Idea Development Award 
Deadline: August 28

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

Pilot Grants: Planning for Multi-Investigator Proposals
Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

NIH and AHRQ Announce Updated Policy for Application Submission (NOT-OD-14-074)

NIH Will Open the Research Performance Progress Report (RPPR) for All Type 5 Non-SNAP Progress Reports on April 25, 2014 (NOT-OD-14-079)

Notice of NIH HeLa Genome Sequence Data Submission and Access Policy (NOT-OD-14-080)

Notice of NIH Improving the Financial Conflict of Interest (FCOI) Module for Submission of Financial Conflict of Interest Reports to the NIH Beginning on April 25, 2014 (NOT-OD-14-081)

Public Pre-application Webinar for PAR-14-067 "Fundamental Mechanisms of Affective Science and Decisional Processes in Cancer Control (U01)" (NOT-CA-14-042)

Prospective Studies on the Impact of Generic Immunosuppressants on Acute Rejection and Long Term Graft survivals (U01) (RFA-FD-14-020)

Limited Competition: Transdisciplinary Collaborative Centers for Health Disparities Research Coordinating Center (U54)(RFA-MD-14-002)

Limited Competition: NIMHD Exploratory Centers of Excellence Pilot Research Projects (P20) (RFA-MD-14-003)

Undiagnosed Diseases Gene Function Research (R21) (RFA-RM-14-005)

Translational Research at the Aging/Cancer Interface (TRACI) (R21)(PA-12-135)

Mechanisms of Alcohol-Associated Cancers (R01)(PA-12-146)

Mechanisms of Alcohol-Associated Cancers (R21)(PA-12-147)

Exploratory Clinical Trials of Mind and Body Interventions for NCCAM High Priority Research Topics (R34) (PAR-14-182)

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to Gillian Irwin at gillian.irwin@case.edu.

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EVENTS

calendar

Mon, April 21

Immunology Special Seminar
Andrei Medvedev, PhD
Adjunct Associate Professor, Microbiology and Immunology, University of Maryland
Associate Professor, Immunology, University of Connecticut Health Center
Topic: Regulation of TLR Signaling Pathways
12 pm NC1-202 Cleveland Clinic

Pathology Seminar
Philip D. Stahl, PhD
Professor, Cell Biology and Physiology
Washington University in St. Louis
Topic: Endocytosis and Ectocytosis and the Primate Specific Oncogene TBC1D3
12 pm WRB 1-413

GMI Research Seminar
Jeff Bhasin, PhD
Ting Lab, Genomic Medicine Institute
Cleveland Clinic
Topic: DNA Methylation Sequencing of Prostate Tumors Reveals Possible Molecular Mechanisms for Cancer Aggressiveness
12:30pm NE1-205 Cleveland Clinic

Physiology & Biophysics Seminar
Bernard "Bob" Gutin, PhD
Professor Emeritus of Pediatrics and Physiology
Medical College of Georgia
Professor Emeritus, Applied Physiology, Teachers College
Columbia University
Topic: How Can Youths Develop Lean and Healthy Bodies? A New Perspective
4 pm Robbins E-501


Tues, April 22

Molecular Genetics Departmental Seminar
Jinyu Wang
Graduate Student, Runge lab, Molecular Genetics
Cleveland Clinic
Topic: Establishment of Heterochromatin Induced by Telomere Formation
9:30am NE1-205 Cleveland Clinic

Immunology Seminar Series
Elizabeth Liu
PhD Candidate, Subauste lab, Pathology
CWRU/UH
Topic: The Autophagy Pathway and Toxoplasma Gondii Infection
12 pm BRB 105

Cancer Biology Seminar Series
Cesar Ercole, MD
Urology Oncology Fellow, Sharifi lab, Cancer Biology
Cleveland Clinic
Topic: Androgen Metabolism in Fresh Human Prostate: An Ex Vivo Experience
2 pm NC1-202 Cleveland Clinic

Lerner Research Institute Seminar
Emina Huang, MD, FACS, FASCRS
Staff and Vice-Chair, Stem Cell Biology & Regenerative Medicine, Lerner Research Institute
Cleveland Clinic
Topic: Colitis-associated Cancer: A Model for Interrogating Inflammation and Oncogenesis
4 pm NA5-03 Cleveland Clinic

Special Physiology & Biophysics Seminar
Ruisheng Liu, MD, PhD
Associate Professor, Physiology & Biophysics
University of Mississippi Medical Center
Topic: A Novel Renal Mechanism for Salt-sensitive Hypertension
4 pm Robbins E-501

Div. of Hem/Onc Fellows Case Conference
Michelle Treasure, MD
Topic: Malignant Gliomas
AND
Carlos Silva, MD
Fellows, Div. of Hem/Onc
CWRU/UH
Topic: Acute Leukemia is Not Always a Terrible Diagnosis
5 pm SCC Learning Lab


Wed, April 23

1st Annual Multidisciplinary Colorectal Oncology Course
InterContinental Hotel & Bank of America Conference Center
Register

Hematology and Oncology Division Research Conference
Joseph Gibbons, MD 
Assistant Professor, Div. of Hem/Onc
CWRU/UH
Topic: Investigator Responsibilities in FDA Regulated Research
8 am Lerner B-151

Pathology Grand Rounds
Chen Liu, MD, PhD
Professor & Associate Chair
Director, Gastrointestinal and Liver Pathology Section & Fellowship Program
Endowed Chair in Gastrointestinal and Liver Research
Department of Pathology, Immunology, Laboratory Medicine
University of Florida
Topic: Biomarkers and Therapeutic Targets in Hepatocellular Carcinoma
8 am Pathology Amphitheatre

Academic Drug Development Seminar
Jennifer Carew, PhD
Associate Staff, Translational Hematology and Oncology
Cleveland Clinic
Topic: Targeting Autophagic Degradation for Cancer Therapy
4 pm Global Cardiovascular Innovations Center (GCIC)

Frontiers in Biological Sciences
Baldomero Olivera, PhD
Distinguished Professor
University of Utah
Topic: The Conotoxins and Constellation Pharmacology
4 pm Robbins E501


Thurs, April 24

GI SPORE Retreat
8:15 am Dively 202
Registration

Molecular Genetics Seminar
Donal Luse, PhD
Staff, Molecular Genetics
Cleveland Clinic
Topic: Gdown1 Versus TFIIF: Competition for Control of Transcript Elongation by RNA Polymerase II
9:30 am NE1-205 Cleveland Clinic

Pathology Faculty Candidate
Benjamin Youngblood, PhD
Research Track Faculty
Emory University 
Topic: Epigenetic Regulation of T cell Differentiation during Acute and Chronic Viral Infections
10 am WRB 5-136

Biomedical Engineering Seminar
Russell Fedewa, PhD
Project Staff, Vince lab, Biomedical Engineering
Cleveland Clinic
Topic: Looking Beyond Grayscale Ultrasound: Leveraging the Physics of Ultrasound to Improve Patient Care
11 am NE1-205 Cleveland Clinic

Immunology Journal Club
Fred Allen
Student, Immunology
CWRU
Topic: Polarized Release of T-cell-Receptorenriched Microvesicles at the Immunological Synapse
12 pm WRB 5-136

Molecular Biology & Microbiology Seminar
Daniel Popkin, MD, PhD
Assistant Professor, Dermatology
CWRU/UH
Topic: Combating Persistent Viral Infections with Cell-specific Therapies
1 pm Rottman Seminar Room, Wood W203

Frontiers in Biological Sciences Lecture Series
Christopher M. Dobson, FRS
Professor, Chemistry
University of Cambridge, UK
Topic: The Amyloid Phenomenon and its Significance
4 pm WRB 1-413


Fri, April 25

Hematology/Oncology Fellows Conference/Curriculum Series
Topic: TBD
8 am Breen Conference Rm.

Cancer Center Seminar Series
Junran Zhang, MD, PhD
Assistant Professor, Radiation Oncology
CWRU/UH
Topic: DNA Double Strand Break Responses, Cancer and Cancer Therapy
12 pm BRB 105

Molecular Biology and Microbiology
Roxana Rojas, MD, PhD
Assistant Professor, Molecular Biology and Microbiology
CWRU
Topic: Novel Strategies to Fight Tuberculosis through the Regulation of Host Pathways and Immunity
1 pm Rottman Seminar Room W203

Hematopoietic Disorders Program Meeting
3:15 pm WRB 1-403

Cancer Center Research in Progress
Clark W. Distelhorst, MD
Professor, Div. of Hem/Onc
CWRU/UH
Topic: Targeting Calcium Signaling for Cancer Research
4 pm WRB 3-136


Mon, Apr 28

Genomic Medicine Institute Seminar
Lynn Bekris, PhD
Genomic Medicine Institute
Cleveland Clinic
Topic: Functional Regulatory Region Genetic Variants and Alzheimer's Disease
12:30pm in NE1-205 Cleveland Clinic

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Screening for Cancer in Women: 2014
May 21
Embassy Suites - Rockside Rd. - Independence
Details

Case CCC Annual Scientific Retreat
July 10-11
Wolstein Research Bldg/Corporate College East

ADDITIONAL UPCOMING SEMINARS & EVENTS

ASCO Review
June 26
InterContinental Hotel & Bank of America Conference Center
Cleveland, OH

American Society for Matrix Biology Biennial Meeting: Integrating Extracellular Matrix and Cellular Networks in Biology and Medicine
October 12-15
Cleveland, OH
Details

Society for Integrative Oncology
October 26-28, 2014
Houston, Texas
Details