CASE CCC IN THE NEWS
Cleveland Clinic's Dr. Charis Eng: A Q & A with the Cancer Geneticist
The Plain Dealer - Mar 14, 2014
Dr. Charis Eng, Chair of the Genomic Medicine Institute and member of the Case Comprehensive Cancer Center, is a rock star in the scientific world. Even before she arrived at the Cleveland Clinic in the fall of 2005, hand-picked to assemble the hospital's Genomic Medicine Institute (housed in the Center for Genomics Research, which had opened earlier that year), of which she is founder and chair, Eng had already made her mark...During a recent interview with The Plain Dealer, Eng talked about the importance of mentors, the challenge she has faced being a woman scientist, and the benefits of wine – in medicine and in life.
Statewide Colorectal Cancer Prevention Study is Screening Patients, Relatives for Lynch Syndrome
The Plain Dealer - Mar 12, 2014
Four hospitals in Northeast Ohio have joined a colorectal cancer prevention and research study that aims to screen everyone in the state diagnosed with colon cancer since Jan. 1, 2013 in an effort to help them avoid additional cancers. Researchers not only want to identify every patient who has a genetic disorder called Lynch syndrome, they also want to test the patients' first-degree relatives to see if they, too, are at higher risk of developing colorectal cancer and other cancers. Starting this month, Cleveland Clinic, Fairview Hospital, MetroHealth System and Summa Western Reserve Hospital joined the Ohio Colorectal Cancer Prevention Initiative...At the Cleveland Clinic, the routine screening for Lynch syndrome in new colorectal cancer and endometrial cancer patients whose tumors are surgically removed has been in place for several years. "There are definitely red flags," said Dr. Matthew Kalady, a colorectal surgeon at the Clinic. Among the signs: a diagnosis at a younger age, cancer on the right side of the colon, and an extensive family history of the disease are among the signals.
University Hospitals: Screenings Save Pledge
Fox 8 - Mar 11, 2014
In honor of Colon Cancer Awareness Month, Drs. Greg Cooper and John Dumot of University Hospitals Case Medical Center and the Case Comprehensive Cancer Center discuss the six biggest myths about colon cancer.
No Apparent Increased Risk of Myelodysplastic Syndrome With Definitive Radiotherapy in Prostate Cancer
Mar 11, 2014
Exposure to ionizing radiation has been associated with increased risk of myelodysplastic syndrome, and it remains unclear whether radiation doses used in prostate cancer treatment result in increased risk. In a retrospective cohort study reported in the Journal of the National Cancer Institute,Dr. Sudipto Mukherjee et al found no significantly increased risk of myelodysplastic syndrome over relatively short-term follow-up.
Stereotactic Radiosurgery for More than Four Brain Metastases
Lancet Oncology - Mar 10, 2014
In this piece, Drs. Simon Lo, Mitchell Machtay and Andrew Sloan of University Hospitals Case Medical Center and the Case Comprehensive Cancer Center comment on the use of stereotactic radiosurgery for patients with more than four brain mestastases.
Personalized Medicine Revolution Gains Momentum
Cure Magazine - Mar 3, 2014
In no cancer is that process clearer than in chronic myeloid leukemia (CML), a "disease defined by its biomarker," the Philadelphia chromosome, according to Mikkael A. Sekeres, director of the leukemia program at the Cleveland Clinic in Cleveland, chairman of the Food and Drug Administration's (FDA) oncologic drugs advisory committee, and member of the Case Comprehensive Cancer Center. Individuals with chronic phase CML carry this genetic abnormality in their leukemia cells, and this "fusion gene" encodes a protein called BCR-ABL, which tells leukemia cells to "grow, grow, grow," he says, crowding out healthy blood cells and damaging bone marrow.
Colorectal Cancer Prevention and Detection: Brief Reports From the 2014 ASCO GI Cancers Symposium
Gastroenterology and Endoscopy News - Mar 2014
Are patients who undergo colonoscopy more likely to undergo screening for other cancers? Researchers from Case Western Reserve University, Cleveland, addressed this question in a study of 717,334 Medicare patients who underwent colonoscopy at two time points—between 2004 and 2008 and between 2009 and 2010. Examining the rates of mammography and prostate-specific antigen (PSA) testing in the later period, the investigators found that individuals with more than one previous colonoscopy were five times more likely to undergo mammography and nearly three times more likely to undergo PSA testing, reported Gregory S. Cooper, MD, Co-Leader for the Cancer Prevention and Control Program at the Case Comprehensive Cancer Center.
January 2014 CTSC Core Utilization Pilot Awards Recipients
Congratulations to the January 2014 CTSC Core Utilization Pilot Awards Recipients
- Tracey Bonfield, PhD: Anti-Inflammatory Properties of Mesenchymal Stem Cells in CF
- Afshin Dowlati, MD: Construction of a small-cell lung cancer tissue microarray
- Justin Lathia, PhD: High throughput flow cytometry screen to identify TNBC adhesion molecules in a CSC-reporter Triple-negative breast cancer (TNBC) model system linked to patient survival
- Parameswaran Ramakrishnan, PhD: Antibody based therapeutics to treat autoimmune diabetes
V Foundation for Cancer Research: Translational Projects in Bladder Cancer
The V Foundation for Cancer Research is interested in funding a translational research project in the focus area of bladder cancer. The Case CCC has been invited to submit ONE LOI. All letters of intent will be considered by a subgroup of the Scientific Advisory Committee of The V Foundation and past grant recipients. After this review, three to five institutions will be invited to submit a grant proposal.
Anyone interested in applying for this grant should contact Kristin Waite (firstname.lastname@example.org) as soon as possible for more information.
Internal LOI Deadline: March 26
External LOI Deadline: April 30
Bladder Cancer Advocacy Network
The Bladder Cancer Advocacy Network (BCAN) is accepting applications for the John Quale Travel Fellowship Program. This is a special opportunity for early career physicians and scientists interested in bladder cancer research to attend the Ninth Annual BCAN Bladder Cancer Think Tank, which will be held held August 7-9, 2014 in San Diego, California.
Deadline: April 14
Request for Proposals for Case CCC Funding for Pilot/Phase I Clinical Trials
The Case CCC is encouraging investigators to submit Letters of Intent (LOI) for Early Phase Clinical Research Support (EPCRS) funding. These in-house funds are available for the conduct of early phase clinical trials of relatively short duration. Priority will be given to trials which are developed jointly between UH and CCF with planned accrual at both institutions. (See revised NCI Cancer Center Support Grant EPCRS guidelines, page 43, Section 2.12). Please submit LOIs to Katarzyna Karelus, Case CCC Clinical Research Office, email@example.com, 216.844.4176.
LOI deadline: April 15
Brian Werbel Memorial Fund
Applications are currently being accepted for summer cancer research fellowship fundingWerbel2014, provided by the Brian Werbel Memorial Fund. This fund was established in 2007 at University Hospitals Case Medical Center, and is dedicated to providing summer fellows an opportunity to focus on cancer research, with the ultimate goal to aid in curing cancer. Brian's hope was to find a cure for cancer – to make a difference in the world, just as he made a difference in the lives of everyone he touched. Applicants must be conducting cancer research with a Case Comprehensive Cancer Center member. Awardees are required to attend the Annual Golf Outing Event, typically held in July.
Deadline: April 25
MARK YOUR CALENDARS
Screening for Cancer in Women: 2014
Registration is now open for Screening for Cancer in Women: 2014, Wednesday, May 21 from 8 am - 3:35 pm at the Embassy Suites Hotel in Independence.
Optimal strategies in cancer screening and detection are constantly evolving, and best practices are changing. This conference will feature speakers from health centers across Northeast Ohio working together to fight cancer, who will offer expert insight, updates, and advice on screening for cancer in women.
This comprehensive symposium is aimed at primary care providers and cancer specialists with updates that can be incorporated into their practices:
- New screening technologies, particularly to detect breast and lung cancer
- Current guidelines for colorectal, skin, lung, breast, and cervical cancer screening
- Impact of the Affordable Care Act
- Racial and economic disparities within cancer screening and detection
- When to refer a patient for a genetics referral or to a high-risk clinic
CME credit will be offered. Visit the conference website for more details and registration information.