On Super Bowl Sunday, the Real Heroic Athlete isn't Even Playing Football: Michael K. McIntyre's Tipoff
Joe Boyle will lace up his running shoes and pound out a marathon – three times around a course through the city where he lives, Bowling Green – not for a payday or a shiny trophy or a trip to Disneyland. He's doing it for his three kids – Ellie, 11, Joey, 8 and Mark, 5 – who don't realize now that their "Captain America" – he's a bigger comic book nerd than any kid – displays more courage every day than all of the larger than life heroes of Marvel. Joe has metastatic kidney cancer. Experimental immunotherapy treatments start soon at the Cleveland Clinic. His diagnosis in 2011 interrupted a dream to run a marathon. So he's planning to fulfill it now, with his Clinic oncologist, Dr. Brian Rini, running alongside him.
New Research Data on Pre-cancers in Breast Tissue Could be Treatment Game-changer
the Plain Dealer - Jan 30, 2014
The findings of a study published today in the journal Cancer Prevention Research (a journal of the American Association for Cancer Research) suggest that patients with two types of breast tissue abnormalities have the same potential to develop breast cancer..."This is a really strong paper; I like the fact that it's changing the way that we think of these lesions," said Dr. Donna Plecha, director of breast imaging at University Hospitals Case Medical Center in Cleveland.
University Hospitals Study: Regular Mammograms for Women in Their 40s Remain Beneficial
The Plain Dealer - Jan 29, 2014
The findings of an expanded study conducted by researchers at University Hospitals Case Medical Center are lending even more credence to the value of screening mammograms for women in their 40s...Led by Dr. Donna Plecha, director of breast imaging at UH, the researchers first began looking at the topic shortly after a task force issued a recommendation in 2009 saying that women don't need regular annual mammograms before age 50.
Paul Fox Donates $1 Million to Establish Endowed Chair; Xiaoxia Li Will be the First Chair Holder
One Case CCC member made an amazing donation to create an endowed chair at the Cleveland Clinic, and another Cancer Center researcher will benefit as the first holder of that chair.
Dr. Paul Fox, professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and the Robert Canova Endowed Chair in Inflammation Research at the Cleveland Clinic, donated $1 million to establish an endowed chair in Molecular Medicine at the Cleveland Clinic. The Fox Chair, which was established as part of the Lerner Research Institute's Endowed Chair Challenge where the Cleveland Clinic matches funds, is the first chair to be established by a staff member at the institute. This chair will provide funding for research to help advance the understanding of molecular mechanisms that underlie disease.
Dr. Xiaoxia Li, Cleveland Clinic Department of Immunology and a professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, will be the first Fox Chair holder. With support provided by the Chair, Dr. Li's goal is to develop new drugs to treat diseases of the immune system.
Vote for Dr. Stan Gerson for the AACR Nominating Committee
Our director, Dr. Stan Gerson, is on the ballot for the American Association for Cancer Research (AACR) Nominating Committee. The election will close on Friday, February 14. Voting instructions will be distributed to all voting members of AACR. Election results will be announced in March 2014 and elected candidates will assume office at the AACR Annual Meeting 2014 in April.
Please show your support for Dr. Gerson and vote for him! It would be great to have local votes that place our director on the Nominating Committee, which selects candidates for major awards, the annual meeting program committee, and the slate of candidates for national positions.
American Cancer Society, Stand Up To Cancer Announce $20 Million Partnership
From Philanthropy News Digest
The American Cancer Society and Stand Up To Cancer (SU2C), an initiative of the Entertainment Industry Foundation, have announced a partnership to advance research efforts in the fight against cancer.
To that end, each organization has committed $10 million over three years toward their first project, the creation of a "dream team" of researchers focused on developing new therapies for lung cancer, to which Bristol-Myers Squibb will provide $5 million through SU2C. Later this year, the American Association for Cancer Research, an SU2C partner, will issue a call for research proposals, with members of the team to be announced in 2015. Lung cancer is the leading cause of cancer death among both men and women in the United States, claiming the lives of approximately 160,000 people annually. [more]
Next-Generation Gene Expression and Data Analysis Workshop
The Gene Expression and Genotyping Core Facility (GEGF) is sponsoring a workshop on February 5 in the Wolstein Research Building that will provide a comprehensive review of the new Affymetrix Human Transcriptome Array. The morning session will concentrate on describing what type of information the array can provide and how this product can enhance your research efforts. This session will also discuss sample preparation for the array, sample quantity needed and sample types that will work with this technology. The afternoon session will be smaller and more hands-on, and will provide a more in-depth discussion of software and data analysis. Please contact Marty Veigl, Director of the GEGF for more information.
Inaugural Case Comprehensive Cancer Center Academic Drug Development Seminar
The Inaugural Case Comprehensive Cancer Center Academic Drug Development Seminar, will be held on February 26 at 4pm in the Global Cardiovascular Innovation Center, 10000 Cedar Avenue. This first seminar will feature a presentation by Dr. Goutham Narla, Assistant Professor, Medicine and Transformative Molecular Medicine at CWRU/UH, on Drugging the Undruggable: Small Molecule Activators of Tumor Suppressor Genes.
As part of the Case CCC Developmental Therapeutics Program, this series will gather clinicians, scientists, medical chemists, computer-aided drug designers, screeners, and commercialization personnel in the same room as a stimulating presentation so that all attendees can learn and benefit from the sparked interaction. More details will be circulated in the near future, but please save the date and plan to attend this event. Free parking is available.
Screening for Cancer in Women: 2014
Please mark your calendars and plan to attend Screening for Cancer in Women: 2014, on Wednesday, May 21 from 8 am - 3 pm at the Embassy Suites Hotel in Independence.
Optimal strategies in cancer screening and detection are constantly evolving and best practices are changing.
This update is aimed at primary care providers and cancer specialists with guides that can be incorporated into their practices:
CME credit will be offered. Pre-registration is required. Check the Cancer Center website for more information.
Scholar Awards in Studying Complex Systems 2014 Grant Competition
The James S. McDonnell Foundation (JSMF) Scholar Awards program derives from and is consistent with JSMF's commitment to supporting high quality research and scholarship leading to the generation of new knowledge and its responsible application. For Scholar Awards the program's emphasis is furthering the science of complex systems via the continued development of the theory and tools used in the study of complex research questions and not on particular fields of research per se. JSMF is particularly interested in projects attempting to apply complex systems approaches to coherently articulated questions.
Deadline: March 12
Brian Werbel Memorial Fund
Applications are currently being accepted for summer cancer research fellowship funding, provided by the Brian Werbel Memorial Fund. This fund was established in 2007 at University Hospitals Case Medical Center, and is dedicated to providing summer fellows an opportunity to focus on cancer research, with the ultimate goal to aid in curing cancer. Brian's hope was to find a cure for cancer – to make a difference in the world, just as he made a difference in the lives of everyone he touched. Applicants must be conducting cancer research with a Case Comprehensive Cancer Center member. Awardees are required to attend the Annual Golf Outing Event, typically held in July.
Deadline: April 25
PREVIOUSLY ANNOUNCED OPPORTUNITIES
NIH Center for Accelerated Innovations at Cleveland Clinic Technology Development Program
National CENter for ReGenerAtive Medicine UnderGraduate StudEnt Summer Program (ENGAGE)
NIH BULLETIN – Notices and Funding Opportunities
Notice of Extension of the Response Date for NOT-CA-14-014 "Request for Information (RFI) on Sharing Precursors for Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT) Imaging Agents" (NOT-CA-14-030)
Updated Electronic Application Forms (FORMS-C) Now Available for Administrative Supplement (non-competing Type 3), Successor-in-Interest (Type 6), and Change of Grantee Organization (Type 7) Applications (NOT-OD-14-044)
HELP US HELP YOU!
If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to Gillian Irwin at firstname.lastname@example.org.
Genetics Student Seminar
Student, Genetics and Genome Sciences
Topic: Decoding GWAS: Combinatorial Effects of Non-coding Variants
11 am BRB 105
Pathology Research Seminar Series
PhD Candidate, Schiemann lab, Pathology
Topic: Mechanisms of Oncogenic TGF-beta Signaling in Breast Cancer Metastasis
12 pm WRB 1-413
Physiology and Biophysics Seminar
Daniel L. Minor, Jr., PhD
Professor, Cardiovascular Research Institute
University of California-San Francisco
Topic: Structural and Chemical Biology Studies of Ion Channels
4 pm SOM/Robbins Building E-501
Cellular and Molecular Medicine Seminar Series
Shiyou Chen, PhD
Associate Professor, Physiology & Pharmacology
University of Georgia College of Veterinary Medicine
Topic: TGF-beta Signaling in Smooth Muscle Differentiation and Vascular Remodeling
10 am NC1-202 Cleveland Clinic
Immunology Seminar Series
PhD Candidate, Dubyak lab, Pathology
Topic: Caspase-1 Dependent Pyroptosis: A Mode of Inflammatory Cell Death
PhD Candidate, Abbott lab, Pathology
Topic: Novel IKK Phosphorylation of E3 Ubiquitin Ligases in Inflammation
12 pm BRB 105
Ophthalmology and Visual Sciences Speaker Series
Przemyslaw Sapieha, PhD
Assistant Research Professor, Ophthalmology
University of Montreal
Topic: Neurovascular and Neuroimmune Crosstalk in Retinopathy
12 pm Wood 331
Cancer Biology Seminar
Candece Gladson, MD
Professor, Cancer Biology
Topic: Regulation of Angiogenesis in Glioblastoma
2 pm NC1-202 Cleveland Clinic
DNA Damage/Repair Focus Group Meeting
Scott Welford, PhD
Assistant Professor, Radiation Oncology
Title: Polyamine Catabolism and Therapeutic Resistance in Glioblastoma Multiforme
4 pm WRB 3-136
Hematology and Oncology Division Research Conference
8 am Lerner B-151
Next-generation Gene Expression and Data Analysis Workshop
10 am-3 pm WRB
Pathology Faculty Candidate
Tsan Sam Xiao, PhD
Chief of Structural Immunobiology Unit
Laboratory of Immunology
Topic: Molecular Mechanisms of Nucleic Acid Sensing in Infection and Inflammation
11 am WRB 5-136
Cancer Imaging Program Meeting
12 pm WRB 2-136
Genetics and Genome Sciences Journal Club
Topic: Tumors Give up their Secrets: The Mutational Landscape of 12 Major Cancer Types
12 pm BRB 732
Immunology Journal Club
Topic: IL-32 Promotes Angiogenesis
12 pm WRB 5-136
Hematology/Oncology Fellows Conference/Curriculum Series
8 am Breen Conference Rm.
Taussig Cancer Institute Grand Rounds
Jessica Mester, MS, CGC
Genomic Medicine Institute
Topic: PTEN: When Overgrowth Bumps into Cancer
8 am R3/002-003 Cleveland Clinic
Cancer Center Seminar Series
Nima Sharifi, MD
Associate Staff, Cancer Biology
Kendrick Family Endowed Chair for Prostate Cancer Research
Lerner Research Institute
Topic: Androgen Metabolism in Prostate Cancer: From Mechanism to Therapy
12 pm BRB 105
Cancer Center Research in Progress
Graduate Student, Huang lab, Pathology
Iuliana Bobanga, MD
Surgical Resident, Huang lab, Pathology
Topic: Inflammatory Chemokines CCL3 and CCL4 Alter Immunogenicity of Mouse Colorectal Cancer In Vivo
4 pm WRB 3-136
Screening for Cancer in Women: 2014
Embassy Suites - Rockside Rd. - Independence
Case CCC Annual Scientific Retreat
Wolstein Research Bldg/Corporate College East
2014 Multidisciplinary Head and Neck Cancer Update
Sanibel Harbour Marriott Resort & Spa
Fort Myers, FL
International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Radiosurgery
The Naples Beach Hotel & Golf Club