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July 1, 2013


Stan Gerson, MD
Director, Case CCC

RFI: Opportunities for Cancer-relevant Innovative Technologies with Transformative Potential

The NCI is requesting more information on the need to support new cancer oriented technologies. Collectively, our responses will help prioritize grant RFAs and even supplemental grants to NCI-designated Cancer Centers. Please copy me on your response because it will help me advocate for your good ideas. The deadline for our input is July 15.

Some suggested technology needs that come to mind include:

  • high throughput drug/shRNA screening including robotics and informatics/docking software
  • cloud-based computing with security for data sharing and storage
  • advances in imaging technology especially in clinical research, including PET agents

Please bring your ideas forward!


Case Comprehensive Cancer Center Earns "Outstanding" Rating; Wins Five-Year Federal Grant Renewal
Jun 27, 2013
The Case Comprehensive Cancer Center (Case CCC) again demonstrated the compelling power of partnership in securing an overall rating of "outstanding" and a five-year renewal of its grant from the National Cancer Institute (NCI).

Hosted at Case Western Reserve, the center is a collaboration among the university, Cleveland Clinic and University Hospitals Case Medical Center. The center counts nearly 350 scientists and physicians among its members, and is one of just 41 nationwide to hold the NCI's designation as a comprehensive cancer center. Such elite organizations must demonstrate not only the highest quality of basic and clinical research, but also engage across disciplines and actively educate the public regarding prevention and treatment breakthroughs. The renewal comes with a recommendation the center receive more than $23 million during the course of the grant period.


Despite Increased Scrutiny, Bias Remains 'Concerning' Component of Cancer Research
HemOnc Today - Jun 25, 2013
However, as the cost of cancer research has increased, so has the number of entities with vested financial interests in the outcomes. Consequently, the potential for bias in reporting has never been higher..."Over the last 5 to 10 years, because of the way our system is set up, there has been an increased scrutiny on conflicts of interest," Robert Dreicer, MD, chair of solid tumor oncology and director of clinical research at Cleveland Clinic's Taussig Cancer Institute, told HemOnc Today.

Oncology Times - Jun 24, 2013
Opinion Article by Mikkael A. Sekeres, MD, MS. Genomics. Even the word sounds vaguely technical, like the research focus of some myopic scientist whose femur and tibia have progressively bowed over years due to lack of sun exposure and resultant vitamin D deficiency...

Increased Exposure May be Cause of Rising HPV-cancer Rate 
Helio/Infectious Disease News - June 2013
Comprehensive data from the CDC, National Cancer Institute and the North American Association of Central Cancer Registries continue to show a decline in both incidence and mortality rates for most cancers in the United States..."The expectation is that the vaccines will prevent oropharyngeal cancers in future, but we are not there yet," David Adelstein, MD, a staff physician in the department of solid tumor oncology at Cleveland Clinic's Taussig Cancer Institute, told Infectious Disease News.


Register Today

Registration is open for the 2013 Case CCC Annual Scientific Retreat, July 11-12. The evening of July 11 will be held at the Wolstein Research Building and will feature a keynote address by Kenna Shaw from The Cancer Genome Atlas, followed by a cocktail reception and core facility posters. The retreat will continue on Friday, July 12 at Corporate College East. The day will be filled with interesting scientific sessions and lunchtime discussion tables. The day will wind down with a student poster session and cocktail reception. All attendees must pre-register by Monday, July 8.

Call for Abstracts

All graduate students, postdocs and fellows conducting cancer research are invited to submit abstracts for poster presentations at the Retreat, the evening of July 12. Judges will review abstracts based on the relationship to cancer, novelty, significance of findings, and clarity. Monetary prizes will be awarded. More information is available on the Cancer Center website. The deadline to submit abstracts to is today, July 1 at 5 pm.


Dr. Leahy Receives Grant to Bring New Laser Capture Micro-dissection Machine to CWRU

This past week, Dr. Patrick Leahy received a Notice of Award from the NIH for a Shared Instrument Grant he submitted in March, 2012. Dr Leahy expects the requested instrument, a Leica LMD7000, to be installed within the next 30 days and his training on the instrument to be completed shortly thereafter. Please contact Dr. Leahy at 216.368.0761 or with questions and/or to set up an initial consultation.



Dr. Ma Receives LRI Chairman's Innovative Research Fund Award 2013

Congratulations to Dr. Patrick Ma, who was recently awarded the LRI Chairman's Innovative Research Fund Award 2013 for his project, Integrative Exomic-Epigenomic Sequencing Analysis of Circulating Tumor Cells in Lung Cancer Targeted Therapy.


Alex's Lemonade Stand Foundation 'A' Award

Alex's Lemonade Stand Foundation is accepting applications for the 'A' Award, a three-year grant designed for the early career scientist who wants to establish their career in pediatric oncology research. The ideal applicant has an original project that is not currently being funded. Demonstration of outstanding mentorship and a future commitment to pediatric cancer investigation are critical components of a successful application. Institutional commitment to the applicant is also expected.
Deadline: September 16


MSC 2013: Adult Stem Cell Therapy & Regenerative Medicine

Mark your calendars for MSC 2013: Adult Stem Cell Therapy & Regenerative MedicineAugust 19-21, 2013 at Cleveland Marriott Downtown at Key Center. Presented by the National Center for Regenerative Medicine, this conference will offer a forum for the exchange and discussion of research, ideas, and cutting-edge breakthroughs in translational regenerative medicine. Online registration is open and poster abstracts are being accepted for presentation both in poster format and potentially accepted for platform presentation during the main program as well. Deadline is July 19 for poster abstract submission.


St. Baldrick's Foundation Fall 2013 Infrastructure Grants
LOI Deadline: July 2

James Ewing Foundation of the Society of Surgical Oncology 2013 Fall Clinical Investigator Award in Breast Cancer Research
Deadline: July 8

LCRP Clinical Exploration Award
Pre-Application Deadline: July 9
Application Deadline: October 16

PCRP Exploration-Hypothesis Development Award
LOI Deadline: July 10
Application Deadline: July 31

Case CCC Funding for Pilot/Phase I Clinical Trials
Deadline: July 15

PRCRP Career Development Award
Pre-Application Deadline: July 16
Application Deadline: October 22

PRCRP Idea Award with Special Focus
Pre-Application Deadline: July 16
Application Deadline: October 22

LCRP Concept Award
LOI Deadline: July 17
Application Deadline: July 31

American Cancer Society Clinical Research Professor
LOI Deadline: August 1
Application Deadline: October 15

CTSC Explorys Collaborative Pilot funding
Deadline: August 1

Mesothelioma Applied Research Foundation Research Grant Funding
Deadline: August 2

Uniting Against Lung Cancer Legacy Program
Deadline: August 14

PCRP Collaborative Undergraduate Historically Black Colleges and Universities (HBCU) Student Summer Training Program Award
LOI Deadline: August 15
Application Deadline: September 5

PCRP Physician Research Training Award
LOI Deadline: August 15
Application Deadline: September 5

PCRP Postdoctoral Training Award
LOI Deadline: August 15
Application Deadline: September 5

PCRP Health Disparity Research Award
LOI Deadline: September 18
Application Deadline: October 9

PCRP Population Science Impact Award
LOI Deadline: September 18
Application Deadline: October 9

American Gastroenterological Association Funderburg Research Award in Gastric Cancer
Deadline: August 30

Szent-Györgyi Prize for Progress in Cancer Research
Deadline: September 30

RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families
Deadline: October 15

Foundation for Women's Cancer Claudia Cohen Research Foundation Prize for Outstanding Gynecologic Cancer Researcher 
Deadline: October 23

Foundation for Women's Cancer Dr. John L. Lewis, Jr./William F. O'Connor Foundation Research Prize
Deadline: October 23

Foundation for Women's Cancer Perlman Family CCARE Lynch Syndrome Research Prize 
Deadline: October 23

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Reissue PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])(PA-13-234.html)

Mentored Clinical Scientist Research Career Development Award in Tobacco Control Regulatory Research (K08)

Mentored Research Scientist Career Development Award in Tobacco Control Regulatory Research (K01)(RFA-OD-13-014)

Transition Career Development Award in Tobacco Control Regulatory Research (K22)(RFA-OD-13-015)

Pathway to Independence Award in Tobacco Control Regulatory Research (K99/R00)(RFA-OD-13-016.html)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax


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July 1

Parker Hannifin/Moss Candidate for Professorship in Integrative Oncology
Omer Kucuk MD, FACN
Professor, Hematology and Medical Oncology
Emory University
Topic: Soy Isoflavones in Cancer Treatment, Toxicity Prevention and Survivorship Research
12 pm WRB 3-136

July 2

July 3

Hematology and Oncology Division Research Conference canceled

July 4

July 5

Cancer Center Research in Progress will resume in September

Hematology and Oncology Fellows Conference canceled

Taussig Cancer Institute Grand Rounds will resume in September

Case CCC Calendar

LRI Calendar


Annual Cancer Center Scientific Retreat
July 11-12
Call for Abstracts


National GvHD Health Symposium
November 1