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June 17, 2013

CASE CCC IN THE NEWS

Newly Discovered Gene Strengthens Heart, Fights Breast Tumors
Fox News - Jun 14, 2013
A new study has pinpointed a single gene that appears to both strengthen the heart – without exercise – and halt the spread of breast cancer...Lead researcher Monica Montano, associate professor of pharmacology, Case Comprehensive Cancer Center member, and creator of the mice for the heart and breast cancer research, was very proud of the research's findings..."Many cancer drugs have detrimental effects on the heart," said Dr. Mukesh K. Jain, professor of medicine and director of Case Cardiovascular Research Institute at Case Western Reserve School of Medicine.

High Court: Human Genes Not Patentableā€Œ
The Plain Dealer - Jun 14, 2013
Isolated human genes may not be patented, the Supreme Court ruled unanimously Thursday..."The Supreme Court parsed [the decision] right down the middle correctly, quite appropriately, said Dr. Stanton Gerson, director of the National Center for Regenerative Medicine at Case Western Reserve University.

Partnership between Mercy Cancer Center and University Hospitals Seidman Cancer Center Bring Advanced Cancer Care Close to Home
The Morning Journal - Jun 13, 2013
The Mercy Cancer Center has long been a leader in cancer care for Lorain County, and now a new partnership with University Hospitals Seidman Cancer Center will widen the breadth and depth of services available right here in Lorain...Board certified in obstetrics and gynecology,Kimberly Resnick, M.D., will provide comprehensive gynecological oncology services...Radiation oncologist David Mansur, M.D. will also be available to Mercy patients, with close-to-home appointments being offered at Mercy Allen Hospital and also the Mercy Cancer Center.

Weekly Paclitaxel Produced Fewer Toxicities Than Biweekly Schedule
Helio/HemOnc Today - Jun 13, 2013
"Our results suggest that either regimen will give a good outcome, but the weekly schedule seems to result in better quality of life for patients, causing less muscle and bone pain and allergic reactions," G. Thomas Budd, MD, a medical oncologist in the department of solid tumor oncology at the Cleveland Clinic, said in a press release.

Defining and Refining Clinical Trials
The Plain Dealer - Jun 12, 2013
Research on the Preparatory Education About Clinical Trials, led by Dr. Neal Meropol, chief of the division of hematology/oncology at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine (to name just a few of his titles), indicated that patients said they would be more likely to consider enrolling in a trial after watching video presentations addressing their concerns.

Novel Strategies May Help Boost Clinical Trial Enrollment
Mescape - Jun 11, 2013
"Its overall objective is to recognize the barriers that individual patients have when considering a clinical trial, whether it is a lack of knowledge or awareness of clinical trials or whether its an attitude about clinical trials," saidNeal J. Meropol, MD, chief of the division of hematology and oncology at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine in Cleveland, Ohio, who was involved with both studies.

Cut Radiation Dose in Kids' CT Scans, Researchers Say
Med Page Today - Jun 10, 2013
The study "raises the issue for practitioners [that] we need to understand that there are risks with the tests that we order and that we should make every opportunity to limit the dose that we use for those additional CT scans as well as limit the number of scans overall that are ordered," commentedDavid Mansur, MD, of UH Rainbow Babies & Children's Hospital in Cleveland.

Skin Cells in the Brain Could Cure Cerebral Palsy, Multiple Sclerosis
The Herald - Jun 4, 2013
"It's 'cellular alchemy,'" said Case Western Reserve School of Medicine's assistant professor of genetics and genome sciences and senior author of the study, Dr. Paul Tesar..."The myelin repair field has been hampered by an inability to rapidly generate safe and effective sources of functional oligodendrocytes," said myelin expert and co-author, Dr. Robert Miller..."The progression of stem cell biology is providing opportunities for clinical translation that a decade ago would not have been possible," said Dr. Stanton Gerson, director of the National Center for Regenerative Medicine and professor of Medicine-Hematology/Oncology at the School of Medicine.


FUNDING OPPORTUNITIES

AACR Scientific Achievement Awards

The American Association for Cancer Research (AACR) has issued a call for nominations for the following awards:

  • The 2013 AACR Award for Outstanding Achievement in Cancer Prevention Research, formerly the AACR-Prevent Cancer Foundation Award for Excellence in Cancer Prevention Research, is bestowed upon a scientist from anywhere in the world for seminal contributions to the field of cancer prevention. The research for which the individual is recognized must have been conducted in basic, translational, clinical, epidemiological or behavioral science in cancer prevention research. Furthermore, these studies must have had not only a major impact on the field, but must also have stimulated new directions in this important area.
    Deadline: June 20
  • The 2013 Distinguished Lectureship on the Science of Cancer Health Disparities, funded by the Susan G. Komen Foundation, is awarded to an investigator whose novel work has had or may have a far-reaching impact on the etiology, detection, diagnosis, treatment or prevention of cancer health disparities. This work may involve any discipline in biomedical research including basic, translational, clinical or epidemiological studies.
    Deadline: June 20

DOD Lung Cancer Research Program Concept Award

Applications to the Fiscal Year 2013 (FY13) Lung Cancer Research Program (LCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program (DHP), by the U.S. Army Medical Research Acquisitions Activity (USAMRAA).

  • The Concept Award supports the exploration of a highly innovative new concept or untested theory that addresses an important problem relevant to lung cancer. The Concept Award is not intended to support a logical progression of an already established research project but, instead, allows Principal Investigators (PIs) the opportunity to pursue serendipitous observations. This award mechanism supports high-risk studies that have the potential to reveal entirely new avenues for investigation. Applications must describe how the new idea will enhance the existing knowledge of lung cancer or create an entirely new avenue for investigation.
    LOI Deadline: July 17
    Application Deadline: July 31

Szent-Györgyi Prize for Progress in Cancer Research

The National Foundation for Cancer Research in accepting nominations for the Szent-Györgyi Prize for Progress in Cancer Research. The Prize was established to honor an outstanding researcher whose scientific achievements have expanded our understanding of cancer and cancer causation; whose vision has moved cancer research in new directions; and whose discoveries have resulted in notable advances in cancer prevention, diagnosis, or treatment. The Prize also promotes public awareness of the importance of basic cancer research and encourages the sustained investment needed to accelerate the translation of these research discoveries into new cancer treatments.

Nominations for the Prize may be made by individuals from the research community, industry, government, or other organizations who are sufficiently familiar with the research accomplishments and contributions of the nominee. Self-nominations will not be accepted. Candidates must have made an original discovery or breakthrough in scientific understanding that has led to better prevention, earlier diagnosis, or new treatments for patients with cancer.
Deadline: September 30

RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families

The American Cancer Society has released an RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families. This RFA provides funding for investigators performing pilot and exploratory research studies whose purpose is to test interventions, develop research methodologies, and explore novel areas of research in palliative care of cancer patients and their families. A condition of funding is a clearly defined plan as to how the investigator will use the results of the project to develop larger, extramurally funded research projects. 
Deadline: October 15

PREVIOUSLY ANNOUNCED OPPORTUNITIES

Limited Submission: Hartwell Foundation – Individual Biomedical Research Awards
Internal Deadline: June 17
Internal Application Deadline: July 19
External Deadline: September 16

BCRP Postdoctoral Fellowship Award
Pre-Application Deadline: June 18
Application Deadline: July 2

BCRP Era of Hope Scholar Award
Pre-Application Deadline: June 18
Application Deadline: July 2

PCRP Biomarker Development Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Idea Development Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Laboratory–Clinical Transition Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Synergistic Idea Development Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Transformative Impact Award
Pre-Application Deadline: June 19
Application Deadline: October 9

LCRP Idea Development Award
Pre-Application Deadline: June 20
Application Deadline: October 16

LCRP Career Development Award
Pre-Application Deadline: June 20
Application Deadline: October 16

Alex's Lemonade Stand Foundation Bridge Grants
Deadline: June 21

Alex's Lemonade Stand Foundation Springboard Grant
Deadline: June 21

OCRP Clinical Translational Leverage Award
Pre-Application Deadline: June 21
Application Deadline: September 11

OCRP Resource Development Award
Pre-Application Deadline: June 21
Application Deadline: September 11

BCRP Innovator Award
Pre-Application Deadline: June 25
Application Deadline: September 25

BCRP Breakthrough Award
Pre-Application Deadline: June 25
Application Deadline: September 25

St. Baldrick's Foundation Fall 2013 Infrastructure Grants
LOI Deadline: July 2

James Ewing Foundation of the Society of Surgical Oncology 2013 Fall Clinical Investigator Award in Breast Cancer Research
Deadline: July 8

LCRP Clinical Exploration Award
Pre-Application Deadline: July 9
Application Deadline: October 16

Case CCC Funding for Pilot/Phase I Clinical Trials
Deadline: July 15

PRCRP Career Development Award
Pre-Application Deadline: July 16
Application Deadline: October 22

PRCRP Idea Award with Special Focus
Pre-Application Deadline: July 16
Application Deadline: October 22

American Cancer Society Clinical Research Professor
LOI Deadline: August 1
Application Deadline: October 15

Mesothelioma Applied Research Foundation Research Grant Funding
Deadline: August 2

American Gastroenterological Association Funderburg Research Award in Gastric Cancer
Deadline: August 30

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Change in NCI Policy: R01 and P01 Activity Codes Will No Longer Be Used to Support Investigator-Initiated Phase III Clinical Trials for Medical Interventions and Cancer Imaging Modalities (NOT-CA-13-012)

Research to Characterize and Reduce Stigma to Improve Health (R21)(PA-13-246)

Research to Characterize and Reduce Stigma to Improve Health (R03)(PA-13-247)

Research to Characterize and Reduce Stigma to Improve Health (R01)(PA-13-248)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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EVENTS


June 17

Special Seminar
Haider Mahdi, MD
Fellow, Eng Lab, Genomic Medicine Institute
Cleveland Clinic
Topic: Endometrial Cancer in Patients with Cowden or Cowden-Like Syndrome: Incidence and Spectrum of Germ-line PTEN, SDH and KLLN Alterations
12:30 pm NE1-205 Cleveland Clinic

Frontiers in Digestive Health
Alberto Mantovani, MD
Scientific Director, Istituto Clinico Humanitas
President and Founder, Fondazione Humanitas per la Ricerca
Professor, Pathology
State University of Milan
Topic: Regulatory Pathways in Cellular and Humoral Innate Immunity and Inflammation
1 pm BRB 105


June 18

Radiation Oncology Grand Rounds
Scott Welford, PhD
Assistant Professor, Radiation Oncology
CWRU/UH
Topic: A Role for the Macrophage Migration Inhibitory Factors in Promoting Resistance in the Tumor Microenvironment
8:10 am Lerner Tower B-181


June 19

Hematology and Oncology Division Research Conference
Rami Manochakian, MD
Assistant Professor, Div. of Hem/Onc
CWRU/UH
Topic: Key Topics From the Lung Cancer Program at the Louis Stokes VAMC
8 am Lerner B-151

Molecular Genetics Guest Speaker
Peter Leedman, PhD
Western Australian Institute for Medical Research
University of Western Australia
Topic: MicroRNAs and Cancer - Insights From Down Under
9:30 am NE1-205 Cleveland Clinic


June 20

Cancer Trainee Seminar
James Kasper
Wang Lab, Div. of Nephrology
CWRU
Topic: PI3K/AKT-Eph2 Signaling in Prostate Cancer
AND
Clinical Speaker (TBD)
Clinical Topic: Kidney Cancer
12 pm WRB 3-136


June 21

Hematology and Oncology Fellows Conference
Lisa Rogers, DO 
Professor, Neurology
CWRU/UH
Topic: Neuro-oncology Cases for the Medical Oncologist
8 am Wearn 137/Breen Conference Rm.

Taussig Cancer Institute Grand Rounds
Keith Flaherty, MD
Div. of Hem/Onc
Massachusetts General Hospital
Topic: Exhausting Therapeutic Options in the MAP Kinase Pathway & Building Combination Targeted Therapy Regimens in Melanoma
8 am R3/002-003 Cleveland Clinic

Cancer Center Research in Progress
Eswar Shankar, PhD
Research Associate, Danielpour Lab, Div. of General Medical Sciences (Oncology)
CWRU/UH
Topic: New Insights on Killing Cancer Cells with Sepantronium Bromide
4 pm WRB 3-136

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Annual Cancer Center Scientific Retreat
July 11-12
Overview
Registration
Call for Abstracts

ADDITIONAL UPCOMING SEMINARS & EVENTS

National GvHD Health Symposium
November 1