Newly Discovered Gene Strengthens Heart, Fights Breast Tumors
Fox News - Jun 14, 2013
A new study has pinpointed a single gene that appears to both strengthen the heart – without exercise – and halt the spread of breast cancer...Lead researcher Monica Montano, associate professor of pharmacology, Case Comprehensive Cancer Center member, and creator of the mice for the heart and breast cancer research, was very proud of the research's findings..."Many cancer drugs have detrimental effects on the heart," said Dr. Mukesh K. Jain, professor of medicine and director of Case Cardiovascular Research Institute at Case Western Reserve School of Medicine.
High Court: Human Genes Not Patentable
The Plain Dealer - Jun 14, 2013
Isolated human genes may not be patented, the Supreme Court ruled unanimously Thursday..."The Supreme Court parsed [the decision] right down the middle correctly, quite appropriately, said Dr. Stanton Gerson, director of the National Center for Regenerative Medicine at Case Western Reserve University.
Partnership between Mercy Cancer Center and University Hospitals Seidman Cancer Center Bring Advanced Cancer Care Close to Home
The Morning Journal - Jun 13, 2013
The Mercy Cancer Center has long been a leader in cancer care for Lorain County, and now a new partnership with University Hospitals Seidman Cancer Center will widen the breadth and depth of services available right here in Lorain...Board certified in obstetrics and gynecology,Kimberly Resnick, M.D., will provide comprehensive gynecological oncology services...Radiation oncologist David Mansur, M.D. will also be available to Mercy patients, with close-to-home appointments being offered at Mercy Allen Hospital and also the Mercy Cancer Center.
Weekly Paclitaxel Produced Fewer Toxicities Than Biweekly Schedule
Helio/HemOnc Today - Jun 13, 2013
"Our results suggest that either regimen will give a good outcome, but the weekly schedule seems to result in better quality of life for patients, causing less muscle and bone pain and allergic reactions," G. Thomas Budd, MD, a medical oncologist in the department of solid tumor oncology at the Cleveland Clinic, said in a press release.
Defining and Refining Clinical Trials
The Plain Dealer - Jun 12, 2013
Research on the Preparatory Education About Clinical Trials, led by Dr. Neal Meropol, chief of the division of hematology/oncology at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine (to name just a few of his titles), indicated that patients said they would be more likely to consider enrolling in a trial after watching video presentations addressing their concerns.
Novel Strategies May Help Boost Clinical Trial Enrollment
Mescape - Jun 11, 2013
"Its overall objective is to recognize the barriers that individual patients have when considering a clinical trial, whether it is a lack of knowledge or awareness of clinical trials or whether its an attitude about clinical trials," saidNeal J. Meropol, MD, chief of the division of hematology and oncology at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine in Cleveland, Ohio, who was involved with both studies.
Cut Radiation Dose in Kids' CT Scans, Researchers Say
Med Page Today - Jun 10, 2013
The study "raises the issue for practitioners [that] we need to understand that there are risks with the tests that we order and that we should make every opportunity to limit the dose that we use for those additional CT scans as well as limit the number of scans overall that are ordered," commentedDavid Mansur, MD, of UH Rainbow Babies & Children's Hospital in Cleveland.
Skin Cells in the Brain Could Cure Cerebral Palsy, Multiple Sclerosis
The Herald - Jun 4, 2013
"It's 'cellular alchemy,'" said Case Western Reserve School of Medicine's assistant professor of genetics and genome sciences and senior author of the study, Dr. Paul Tesar..."The myelin repair field has been hampered by an inability to rapidly generate safe and effective sources of functional oligodendrocytes," said myelin expert and co-author, Dr. Robert Miller..."The progression of stem cell biology is providing opportunities for clinical translation that a decade ago would not have been possible," said Dr. Stanton Gerson, director of the National Center for Regenerative Medicine and professor of Medicine-Hematology/Oncology at the School of Medicine.
AACR Scientific Achievement Awards
The American Association for Cancer Research (AACR) has issued a call for nominations for the following awards:
DOD Lung Cancer Research Program Concept Award
Applications to the Fiscal Year 2013 (FY13) Lung Cancer Research Program (LCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program (DHP), by the U.S. Army Medical Research Acquisitions Activity (USAMRAA).
Szent-Györgyi Prize for Progress in Cancer Research
The National Foundation for Cancer Research in accepting nominations for the Szent-Györgyi Prize for Progress in Cancer Research. The Prize was established to honor an outstanding researcher whose scientific achievements have expanded our understanding of cancer and cancer causation; whose vision has moved cancer research in new directions; and whose discoveries have resulted in notable advances in cancer prevention, diagnosis, or treatment. The Prize also promotes public awareness of the importance of basic cancer research and encourages the sustained investment needed to accelerate the translation of these research discoveries into new cancer treatments.
Nominations for the Prize may be made by individuals from the research community, industry, government, or other organizations who are sufficiently familiar with the research accomplishments and contributions of the nominee. Self-nominations will not be accepted. Candidates must have made an original discovery or breakthrough in scientific understanding that has led to better prevention, earlier diagnosis, or new treatments for patients with cancer.
Deadline: September 30
RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families
The American Cancer Society has released an RFA: Pilot and Exploratory Projects in Palliative Care of Cancer Patients and Their Families. This RFA provides funding for investigators performing pilot and exploratory research studies whose purpose is to test interventions, develop research methodologies, and explore novel areas of research in palliative care of cancer patients and their families. A condition of funding is a clearly defined plan as to how the investigator will use the results of the project to develop larger, extramurally funded research projects.
Deadline: October 15
PREVIOUSLY ANNOUNCED OPPORTUNITIES
Limited Submission: Hartwell Foundation – Individual Biomedical Research Awards
James Ewing Foundation of the Society of Surgical Oncology 2013 Fall Clinical Investigator Award in Breast Cancer Research
Case CCC Protocol Specific Research Support (PSRS)
International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
NIH BULLETIN – Notices and Funding Opportunities
Change in NCI Policy: R01 and P01 Activity Codes Will No Longer Be Used to Support Investigator-Initiated Phase III Clinical Trials for Medical Interventions and Cancer Imaging Modalities (NOT-CA-13-012)
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
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Haider Mahdi, MD
Fellow, Eng Lab, Genomic Medicine Institute
Topic: Endometrial Cancer in Patients with Cowden or Cowden-Like Syndrome: Incidence and Spectrum of Germ-line PTEN, SDH and KLLN Alterations
12:30 pm NE1-205 Cleveland Clinic
Frontiers in Digestive Health
Alberto Mantovani, MD
Scientific Director, Istituto Clinico Humanitas
President and Founder, Fondazione Humanitas per la Ricerca
State University of Milan
Topic: Regulatory Pathways in Cellular and Humoral Innate Immunity and Inflammation
1 pm BRB 105
Radiation Oncology Grand Rounds
Scott Welford, PhD
Assistant Professor, Radiation Oncology
Topic: A Role for the Macrophage Migration Inhibitory Factors in Promoting Resistance in the Tumor Microenvironment
8:10 am Lerner Tower B-181
Hematology and Oncology Division Research Conference
Rami Manochakian, MD
Assistant Professor, Div. of Hem/Onc
Topic: Key Topics From the Lung Cancer Program at the Louis Stokes VAMC
8 am Lerner B-151
Molecular Genetics Guest Speaker
Peter Leedman, PhD
Western Australian Institute for Medical Research
University of Western Australia
Topic: MicroRNAs and Cancer - Insights From Down Under
9:30 am NE1-205 Cleveland Clinic
Cancer Trainee Seminar
Wang Lab, Div. of Nephrology
Topic: PI3K/AKT-Eph2 Signaling in Prostate Cancer
Clinical Speaker (TBD)
Clinical Topic: Kidney Cancer
12 pm WRB 3-136
Hematology and Oncology Fellows Conference
Lisa Rogers, DO
Topic: Neuro-oncology Cases for the Medical Oncologist
8 am Wearn 137/Breen Conference Rm.
Taussig Cancer Institute Grand Rounds
Keith Flaherty, MD
Div. of Hem/Onc
Massachusetts General Hospital
Topic: Exhausting Therapeutic Options in the MAP Kinase Pathway & Building Combination Targeted Therapy Regimens in Melanoma
8 am R3/002-003 Cleveland Clinic
Cancer Center Research in Progress
Eswar Shankar, PhD
Research Associate, Danielpour Lab, Div. of General Medical Sciences (Oncology)
Topic: New Insights on Killing Cancer Cells with Sepantronium Bromide
4 pm WRB 3-136
National GvHD Health Symposium