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May 27, 2013

CASE CCC IN THE NEWS

Researchers Use Data to Identify Different Forms of Prostate Cancers and Effective Treatment Options
News Medical - May 24, 2013
Some prostate cancer patients unnecessarily undergo surgery or harsh treatments because science fails to identify the differences between slow-growing and aggressive forms of the disease. Researchers at Case Western Reserve University and Johns Hopkins Medical Institutes are developing technology that allows patients to safely choose to do nothing, opt for relatively mild treatments or take drastic measures. The project is one of several Anant Madabhushi, an associate professor of biomedical engineering at Case Western Reserve and director of the Center for Computational Imaging and Personalized Diagnostics, is involved in.

Five Star Sensation helps fund University Hospitals Seidman Cancer Center
News Herald - May 23, 2013
Dr. Stan Gerson, director of the UH Seidman Cancer Center, said clinical trials and survivorship programs are especially valuable contributions made possible with the money raised by Five Star Sensation, because they often are not covered by patient insurance.


ANNOUNCEMENTS

ASCO Annual Meeting 2013

The Case CCC is pleased to have many members participating in the American Society of Clinical Oncology (ASCO) Annual Meeting, May 31-June 4 in Chicago. To view a list of Cancer Center participation, please click here. We encourage members who are attending the meeting to support their colleagues.

Best of luck to all participants!

Dr. Mikkael Sekeres Named FDA ODAC Chair for Another Term

Mikkael Sekeres, MD, MS, Leukemia Program Director, Cleveland Clinic Taussig Cancer Institute, will remain Chair of the Oncologic Drugs Advisory Committee (ODAC) of the Food and Drug Administration (FDA) for another year. The Committee reviews and evaluates data concerning the safety and effectiveness of marketed and investigational human drug products for use in the treatment of cancer and makes appropriate recommendations to the Commissioner of Food and Drugs. Dr. Sekeres has been a voting member of this Committee for the past three years.

Request for Information: Opportunities for Cancer-relevant Innovative Technologies with Transformative Potential

The NCI is looking for feedback from cancer researchers, clinicians, and other interested members of the community through a Request for Information (RFI). The purpose of the RFI is to seek input on the most important needs and promising opportunities to develop technologies with strong potential for accelerating cancer research or clinical care. NCI is interested in understanding the communities' perspective on areas where state-of-the-art capabilities are insufficient for clinical care or to explore biological or epidemiological facets of cancer. Responses to the RFI will be used for consideration of research priorities and may help to develop future funding opportunities. Please respond by June 30, 2013.


MARK YOUR CALENDARS

Race for the Place- Join Our Team!

The Race for the Place, an event that benefits the Gathering Place, will be held Sunday, June 2 at Beachwood Place Mall. The Case CCC has created a team. Click here to join the team or to show your support by making a donation. Contact Gillian Todd for more information.

Impact of Genomics on Cancer Diagnosis and Treatment: Open Drug Policy Forum

The Case CCC, in partnership with five other Midwest comprehensive cancer centers, will convene a public forum on the emerging revolution in genetic testing known as precision or personalized medicine on Monday, June 10. Experts from the FDA, NCI, CMS, pharmaceutical industry, public health sector, and the cancer research community will participate in dynamic lectures and discussions to consider the complexities of integrating genetic testing into cancer care.

This forum is free and open to the public. Pre-registration required: http://goo.gl/xEuwA.

More information is on the Cancer Center site.

Complying with the NIH Public Access Policy

Staff from the CWRU Cleveland Health Sciences Library will present, Complying with the NIH Public Access Policy, onFriday, June 14 from 9-10:15 am in the Wolstein Research Building Auditorium. This seminar will facilitate compliance with the "Revised Policy on Enhancing Public Access to Archived Publications Resulting from NIH-Funded Research." They will outline the submission process and services available on campus to assist researchers in complying with the policy, which requires that all peer-reviewed manuscripts accepted for publication after April 7, 2008, and resulting fully or in part from NIH-funded research, must be deposited to PubMed Central within twelve months of publication. In addition, these articles must be associated with the NIH grant(s) in NCBI's MyBibliography.


FUNDING OPPORTUNITIES/AWARDS

Limited Submission: Hartwell Foundation – Individual Biomedical Research Awards

CWRU earned an at-large bid in The Hartwell Foundation's Individual Biomedical Research Awards program, and is eligible to nominate two faculty members for proposal submission this year. The foundation funds 10 Hartwell Investigators annually for their innovative, early-stage, cutting-edge biomedical research that has the potential to benefit children. 
Internal Deadline: June 17
Internal Application Deadline: July 19
External Deadline: September 16

Request for Proposals for Case CCC Funding for Pilot/Phase I Clinical Trials

The Case CCC is encouraging investigators to submit Letters of Intent for Early Phase Clinical Research Support (EPCRS; former Protocol Specific Research Support) funding. These in-house funds are available for the conduct of early phase clinical trials of relatively short duration. Priority will be given to trials which are developed jointly between UH and CCF with planned accrual at both institutions. (See revised NCI Cancer Center Support Grant EPCRS guidelines, page 43, Section 2.12).

Please submit LOIs and direct questions about the revised guidelines and funding process to Katarzyna Karelus, Case CCC Clinical Research Office, kxk384@case.edu, 216-844-4176.

Deadline: July 15

DOD Lung Cancer Research Program

Applications to the Fiscal Year 2013 Lung Cancer Research Program (LCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity.

  • The LCRP Idea Development Award promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress toward eradicating deaths from lung cancer.
    Pre-Application Deadline: June 20
    Application Deadline: October 16
  • The LCRP Career Development Award supports early-career, independent investigators to conduct innovative research under the mentorship of an experienced lung cancer researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of lung cancer research.
    Pre-Application Deadline: June 20
    Application Deadline: October 16
  • The LCRP Clinical Exploration Award mechanism is being offered for the first time in FY13. The intent of the LCRP Clinical Exploration Award (CEA) is to support early-phase, proof-of-principle clinical trials and correlative studies to investigate hypothesis-based, innovative interventions and/or avenues of research that have the potential to resolve current clinical barriers and result in a profound impact on the clinical management of lung cancer. 
    Pre-Application Deadline: July 9
    Application Deadline: October 16

DOD Peer Reviewed Cancer Research Program (PRCRP)

Applications to the Fiscal Year 2013 Peer Reviewed Cancer Research Program (PRCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity.

  • The PRCRP Career Development Award supports independent, early-career investigators to conduct innovative research with the mentorship of an experienced cancer researcher (i.e., the Designated Collaborator) as an opportunity to obtain the funding, guidance, and experience necessary for productive, independent careers at the forefront of cancer research.
    Pre-Application Deadline: July 16
    Application Deadline: October 22
  • The PRCRP Idea Award with Special Focus mechanism is intended to support innovative, untested, high-risk/potentially high-reward concepts, theories, paradigms, and/or methods in cancer research that are directly relevant to service members, their families, and other military beneficiaries. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. 
    Pre-Application Deadline: July 16
    Application Deadline: October 22

Alex's Lemonade Stand Foundation

Alex's Lemonade Stand Foundation (ALSF) is accepting applications for the following funding opportunities:

  • ALSF introduces a new funding opportunity for researchers whose projects are in jeopardy due to the decreased funding available from the NIH. ALSF's Bridge Grants are intended to keep scientist's projects on track while they reapply for NIH funding to ensure novel childhood cancer research projects are not compromised. 
    Deadline: June 21
  • ALSF's offers the Springboard Grant in response to cut-backs in NIH funding of new R01 and P01 applications. The Springboard Grant is designed to jump-start new projects with high impact potential for childhood cancer research while other funding is sought. 
    Deadline: June 21

American Gastroenterological Association Funderburg Research Award in Gastric Cancer

The American Gastroenterological Association is accepting applications for the Funderburg Research Award in Gastric Cancer. This award provides support to an established investigator working on novel approaches in gastric cancer research, including the fields of gastric mucosal cell biology; regeneration and regulation of cell growth (not as they relate to peptic ulcer disease or repair); inflammation (including Helicobacter pylori) as precancerous lesions; genetics of gastric carcinoma; oncogenes in gastric epithelial malignancies; epidemiology of gastric cancer; etiology of gastric epithelial malignancies; or clinical research in the diagnosis or treatment of gastric carcinoma. 
Deadline: August 30

PREVIOUSLY ANNOUNCED OPPORTUNITIES

Chris4Life Colon Cancer Pilot Study Grant Program
Deadline: June 1

Department of Defense Ovarian Cancer Academy Award - Early-Career Investigator
Pre-Application Deadline: June 12
Application Deadline: August 28

Department of Defense Ovarian Cancer Research Program Pilot Award
Pre-Application Deadline: June 12
Application Deadline: August 28

Department of Defense Ovarian Cancer Research Program Teal Innovator Award
Pre-Application Deadline: June 12
Application Deadline: August 28 

James S. McDonnell Foundation Postdoctoral Fellowship Award in Studying Complex Systems
Deadline: June 14

Request for Proposals for Pilot Collaborations with LMICs in Global Cancer Research or Global Health Research at NCI-Designated Cancer Centers‌
Deadline: June 14

BCRP Postdoctoral Fellowship Award
Pre-Application Deadline: June 18
Application Deadline: July 2

BCRP Era of Hope Scholar Award
Pre-Application Deadline: June 18
Application Deadline: July 2

PCRP Biomarker Development Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Idea Development Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Laboratory–Clinical Transition Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Synergistic Idea Development Award
Pre-Application Deadline: June 19
Application Deadline: October 9

PCRP Transformative Impact Award
Pre-Application Deadline: June 19
Application Deadline: October 9

OCRP Clinical Translational Leverage Award
Pre-Application Deadline: June 21
Application Deadline: September 11

OCRP Resource Development Award
Pre-Application Deadline: June 21
Application Deadline: September 11

BCRP Innovator Award
Pre-Application Deadline: June 25
Application Deadline: September 25

BCRP Breakthrough Award
Pre-Application Deadline: June 25
Application Deadline: September 25

James Ewing Foundation of the Society of Surgical Oncology 2013 Fall Clinical Investigator Award in Breast Cancer Research
Deadline: July 8

American Cancer Society Clinical Research Professor
LOI Deadline: August 1
Application Deadline: October 15

Mesothelioma Applied Research Foundation Research Grant Funding
Deadline: August 2

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Request for Information (RFI): Input on the Development of a Knowledge Management Center for the "Illuminating the Druggable Genome" Program (NOT-RM-13-018)

Notice Announcing List of Genes of Interest to RFA-RM-13-003 Undiagnosed Diseases Gene Function Research (R21) will be Frequently Updated (NOT-RM-13-019)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax
gillian.irwin@case.edu

HELP US HELP YOU!

If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

Send items to gillian.irwin@case.edu.

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EVENTS


May 27

Happy Memorial Day!


May 28

Molecular Genetics Departmental Seminar
Yanhui Li
Graduate Student, Runge Lab, Molecular Genetics
Cleveland Clinic
Topic: TBD
9:30 am NE1-205 Cleveland Clinic

Immunology Seminar Series 
Yeritza Hernandez
PhD Student, Boom Lab, Pathology
CWRU
Topic: RA Synthesis in Lung APCs and Regulation by Mycobacterium Tuberculosis
12 pm BRB 105

Medicine Grand Rounds
Michael Bronze, MD 
Chairman, Medicine
University of Oklahoma 
Topic: Duty Hour Reform: Is the Beef There?
12 pm Kulas Auditorium, Lakeside 5th Fl.

National Center for Regenerative Medicine
Toshio Suda, MD
Former President ISEH
Professor, Developmental Biology, Sakaguchi Lab
Keio University
Topic: Hematopoiesis Under the Stress
2 pm WRB 2-136


May 29

Hematology and Oncology Division Research Conference
Waqas Rehman, MD
Fellow, Div. of Hem/Onc
CWRU/UH
Topic: Identifying Novel Targets in Advanced Non-small Cell Lung Cancer
8 am Lerner B-151

Ohio Third Frontier Scientific Open Forum
8:30 am - 12 pm WRB 1-413

Hematology and Oncology Special Seminar
Robert Gale, MD, PhD
Visiting Professor, Div. of Experimental Medicine- Hematology
Imperial College 
Topic: Medical Consequences of Nuclear Accidents
1 pm Wearn 137

Cancer Center Faculty Candidate Seminar
Rui Chen, PhD
Postdoctoral Scholar, Genetics
Stanford University
Topic: Towards Precision Medicine with Integrative Personal Omics Profiling
4 pm WRB 3-136


May 30


May 31

Taussig Cancer Institute Grand Rounds canceled

Hematology and Oncology Fellows Conference
Topic: TBD
8 am Wearn 137/Breen Conference Rm.

Cancer Center Research in Progress
Topic: TBD
4 pm WRB 3-136

Case CCC Calendar

LRI Calendar


UPCOMING CANCER CENTER SYMPOSIUMS & EVENTS

Impact of Genomics on Cancer Diagnosis and Treatment: Open Drug Policy Forum
June 10
9 am - 3 pm Wolstein Research Building Auditorium
Draft Agenda
Registration

Annual Cancer Center Scientific Retreat
July 11-12

ADDITIONAL UPCOMING SEMINARS & EVENTS

National GvHD Health Symposium
November 1