Studies Work to Reinvigorate Clinical Trial Participation from Inside Out
PhysBiz Tech - May 17, 2013
"Although clinical trials are the key to developing new, better cancer treatments, less than 10 percent of cancer patients participate in them," said Neal J. Meropol, MD, study author and Chief of the Division of Hematology and Oncology at UHCMC and Case Western Reserve University School of Medicine, in a news release.
Seeking Calm on the Cancer Ward
New York Times - May 16, 2013
By Mikkael Sekeres, MD. When people choose to have their leukemia treated aggressively, it's a big commitment, more so than for almost any other cancer...
Will We See an Angelina Jolie-Effect Due to Her Double Mastectomy Decision?
Fox Business - May 15, 2013
"I congratulate her for doing this," says Dr. Lyndsay Harris, director of the Breast Cancer Program at University Hospitals Case Medical Center. "It raises awareness of the fact that there are certain genetic abnormalities which have a very high risk of developing breast cancer."...While Jolie's decision was bold and her choice to speak out noble, Dr. Julian Kim, division chief of Surgical Oncology at University Hospitals Case Medical Center, says her high likelihood of developing cancer is not common.
Repurposed Cancer Drug to Enter Phase I Trials for Alzheimer's Disease This Year
Med City News - May 14, 2013
ReXceptor thinks it can do that by using a drug that's already been approved by the U.S. Food and Drug Administration. Bexarotene, marketed by Medicis as Targretin, is approved for treatment of cutaneous T-cell lymphoma. But last year, CWRU neuroscience professor Gary Landreth and then-graduate student Paige Cramer published a paper in Sciencedetailing how the drug, when administered to mice, cleared 25 percent of amyloid beta build up in the brain and reversed some of the cognitive impairment of Alzheimer's disease within 72 hours of a single dose.
Cleveland Clinic Receives $1 Million Gift to Stage Cycling Event Benefiting Cancer Research
Crain's Cleveland Business - May 14, 2013
"We are incredibly grateful to Stewart and Donna Kohl for this generous gift," said Dr. Brian J. Bolwell, chairman of Cleveland Clinic's Taussig Cancer Institute, in the release. "Funds raised by VeloSano and its riders will help our physicians and researchers generate discoveries and explore novel therapies for treating cancer."
Study: Simple Exercise Could Reduce Cancer Risk
KSTP.com - May 13, 2013
"Merely sitting the entire day can put you at risk for some cancers, according to some research, and so just getting up through the course of the day every hour and walking around, something that simple can minimize the risk for cancer perhaps," Dr. Dale Shepard of Cleveland Clinic said.
Nanoparticles Offer 'Infinite' Possibilities for Cancer Treatment
Helio/HemOnc Today - May 13, 2013
"Anticancer drugs do not discriminate normal cells from cancer cells," Vinod Labhasetwar, PhD, staff researcher in the department of biomedical engineering at Cleveland Clinic's Lerner Research Institute, told HemOnc Today.
Madabhushi and Team Awarded NIH R21 Clinical Trial Grant for CAD Directed MRI Guided Laser Ablation for Prostate Cancers
Dr. Anant Madabhushi has been awarded a NIH R21 Quick Clinical Trials grant for his project, Decision Support for MRI Guidance and Evaluation of Laser Ablation of Prostate Cancer. In collaboration with interventional radiologist Dr. Dan Sperling at the New Jersey Institute of Radiology, Dr. Madabhushi and his team will be developing and applying advanced computerized image analysis and pattern recognition methods for targeting the focal lesion via laser interstitial thermal therapy (LITT), a novel focal ablative therapy for treating low to intermediate risk of prostate cancers. During the course of this two-year, $540,000 project, Dr. Madabhushi and his team which includes Co-I Dr. Satish Viswanath will also be developing computerized image analysis methods for quantitatively evaluating imaging marker changes to assess treatment response after LITT. Dr. Madabhushi and Dr. Sperling expect to be able to enroll 30 patients during the course of this clinical trial which is being sponsored by the National Cancer Institute.
MARK YOUR CALENDARS
Race for the Place- Join Our Team!
The Race for the Place, an event that benefits the Gathering Place, will be held Sunday, June 2 at Beachwood Place Mall. The Case CCC has created a team. Click here to join the team or to show your support by making a donation. Contact Gillian Todd for more information.
Impact of Genomics on Cancer Diagnosis and Treatment: Open Drug Policy Forum
The Case CCC, in partnership with five other Midwest comprehensive cancer centers, will convene a public forum on the emerging revolution in genetic testing known as precision or personalized medicine on Monday, June 10. Experts from the FDA, NCI, CMS, pharmaceutical industry, public health sector, and the cancer research community will participate in dynamic lectures and discussions to consider the complexities of integrating genetic testing into cancer care.
This forum is free and open to the public. We are nearly at capacity, so please register today if you are planning to attend: http://goo.gl/xEuwA.
More information is on the Cancer Center site.
Annual Scientific Retreat
The Annual Cancer Center Scientific Retreat will commence the evening of Thursday, July 11 with a speaker and reception in the Wolstein Research Building Auditorium. The Retreat will continue the next day, Friday, July 12, at Corporate College East. The agenda is still be finalized. Details will be circulated soon!
Department of Defense Breast Cancer Research Program
Applications to the Fiscal Year 2013 Breast Cancer Research Program (BCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity. The BCRP challenges the scientific community to design research that will address the urgency of ending breast cancer. Specifically, the BCRP seeks to accelerate high–impact research with clinical relevance, encourage innovation and stimulate creativity, facilitate multidisciplinary collaborations, and support future breast cancer leaders.
Department of Defense Prostate Cancer Research Program
Applications to the Fiscal Year 2013 Prostate Cancer Research Program (PCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity. The mission of the FY13 PCRP is to find and fund research that will lead to the elimination of death from prostate cancer and enhance the well–being of men experiencing the impact of the disease.
Department of Defense Ovarian Cancer Research Program
Applications to the Fiscal Year 2013 Ovarian Cancer Research Program (OCRP) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program, by the U.S. Army Medical Research Acquisitions Activity. The overall goal of the FY13 OCRP is to eliminate ovarian cancer by supporting innovative, high–impact research.
2013 Fall Clinical Investigator Award in Breast Cancer Research
The James Ewing Foundation of the Society of Surgical Oncology (SSO) and Susan G. Komen for the Cure® are accepting applications for the 2013 Fall Clinical Investigator Award in Breast Cancer Research. The purpose of this award is to promote patient-oriented research conducted by surgical oncologists in clinical and translational science, and is open to surgical oncologists within 10 years of completion of training. Applicants must be full SSO members for at least six months prior to application submission.
Deadline: July 8
American Cancer Society Clinical Research Professor
The American Cancer Society offers a limited number of grants to mid-career investigators who have made seminal contributions in the area of cancer control that have changed the direction of clinical, psychosocial, behavioral, health policy or epidemiologic cancer research. Furthermore, it is expected that these investigators will continue to provide leadership in their research area.
LOI Deadline: August 1
Application Deadline: October 15
PREVIOUSLY ANNOUNCED OPPORTUNITIES
NCI Provocative Questions
James S. McDonnell Foundation Postdoctoral Fellowship Award in Studying Complex Systems
Case CCC Protocol Specific Research Support (PSRS)
International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
NIH BULLETIN – Notices and Funding Opportunities
Notice of Change to Funds Available and Anticipated Number of Awards for RFA-FD-13-020 Collection of Dose Adjustment and Therapeutic Monitoring Data to Aid Narrow Therapeutic Index Drug Classification (U01)(NOT-FD-13-009)
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
HELP US HELP YOU!
If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!
Send items to email@example.com.
Mohammed Orloff, PhD
Project Scientist, Genomic Medicine Institute
Topic: Integrative 'Omics' Reveal Inflammatory Gene Network Associated with Barrett Esophagus/Esophageal Adenocarcinoma
12:30 pm NE1-205 Cleveland Clinic
CTTE-2013 Short Course: Cell-based Therapies and Tissue Engineering
Camillo Ricordi, MD
University of Miami
Topic: Moving Cell-based Therapies from the Bench to the Bedside: Challenges and Opportunities
5 pm Clapp 108
Radiation Oncology Grand Rounds
Anant Madabhushi, PhD
Associate Professor, Biomedical Engineering
Topic: Quantitative Data Convergence: Implications in Targeted Therapy and Predicting Disease Aggressiveness
8:10 am Lerner B-181
Molecular Genetics Departmental Seminar
Melissa Mullen Davis, PhD
Postdoctoral Research Fellow, Luse Lab, Molecular Genetics
Topic: The Pausing Factor Gdown1 Can Load into RNA Polymerase II Complexes Despite Competition From the Essential Initiation Factor TFIIF
9:30 am NE1-205 Cleveland Clinic
Immunology Seminar Series
Graduate Student, Cooper Lab, Dermatology
Topic: Identifying Monocyte Populations in Human Psoriasis and a Murine Psoriasis Model
Graduate Student, Harding Lab, Pathology
Topic: Trafficking of Immune Stimuli During Mycobacterium Infection
12 pm WRB 1-413
Medicine Grand Rounds
Charles Carpenter, MD
Director, AIDS Center
Physician in Chief
Topic: A Unique Epidemic: The First Three Decades
12 pm Kulas Auditorium, Lakeside 5th Fl.
Theodore J. Castele Lecture
Sanjiv Sam Gambhir, MD, PhD
Virginia and D.K. Ludwig Professor in Cancer Research
Topic: Novel Strategies for the Earlier Detection of Cancer
5 pm WRB 1-413
Hematology and Oncology Division Research Conference
Brad Clifford, MD
Fellow, Div. of Hem/Onc
Topic: EGFR Testing in African American Non-small Cell Lung Cancer Patients — A Review of Discrepant Data
8 am Lerner B-151
Pathology Grand Rounds
Anand Dighe, MD, PhD
Associate Professor, Pathology
Topic: Clinical Laboratory Informatics: Building an Infrastructure to Enhance Value
8 am Institute of Pathology B22
Cancer Center Faculty Candidate
Pier Paolo Scaglioni, MD
Assistant Professor, Hematology/Oncology
UT Southwestern/Simmons Comprehensive Cancer Center
Topic: Genotype-specific Cancer Vulnerabilities: The Case of PML-RARA and Mutant KRAS
11 am WRB 3-136
Topic: DNA, RNA and Systems Biology for Yesterday, Today and the Future
11:30 am WRB 1-413
RSVP to firstname.lastname@example.org
Riccardo Dalla-Favera, MD
Professor and Director, Institute for Cancer Genetics
Uris Professor of Pathology
Topic: Molecular Pathogenesis of B Cell Lymphoma
12 pm NC1-202 Cleveland Clinic
Immunology Journal Club
Graduate Student, Huang Lab, Div. of Pediatric Hem/Onc
Topic: Trypanosoma Cruzi Trans-sialidase Initiates a Program Independent of the Transcription Factors RORɤt and Ahr That Leads to IL-17 Production by Activated B Cells
12 pm WRB 5-136
Breast Cancer 2013: Seeing the Future
8 am - 3 pm Doubletree by Hilton Cleveland East Beachwood
Hematology and Oncology Fellows Conference
8 am Wearn 137/Breen Conference Rm.
Taussig Cancer Institute Grand Rounds
Shetal Shah, MD
Topic: Imaging Therapy Response: Practical Tips
8 am R3/002-003 Cleveland Clinic
Cancer Center Research in Progress
Deborah Sim Barkauskas
Graduate Student, Huang Lab, Pathology
Topic: Watching Cells Crossing the Blood-Brain Barrier: Implication for Autoimmunity, Cell Therapy and Tumor Metastasis
4 pm WRB 3-136
Annual Cancer Center Scientific Retreat
National GvHD Health Symposium