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May 13, 2013


University Hospitals, Philips Healthcare Align as Charter Tenant of Global Center for Health Innovation
Cleveland Business Connects Magazine- May 2013
Pablo Ros, MD, professor and chairman of the department of radiology at UH Case Medical Center and Case Western Reserve University, says UH and Phillips will use their third-floor exhibit space to highlight the lifesaving innovations that have and continue to result from their long-standing association.

New Prostate Cancer Test First Studied at Cleveland Clinic Helps Predict Cancer Risk
Plain Dealer - May 8, 2013
"This is really a boon for patients," said urologist Dr. Eric Klein, chairman of the Glickman Urological and Kidney Institute at the Clinic who oversaw the research. Klein said he hopes the new test will address the reluctance that many patients have when given the option to "watch and wait," and the reluctance many physicians have of offering that option.

The Race on Mother's Day, to Raise Money for Breast Cancer Research, is May 12 at Legacy Village in Lyndhurst
Plain Dealer - May 8, 2013
"We are incredibly proud and thankful to be associated with The Race," said Dr. Lyndsay Harris, director of the Breast Cancer Program at University Hospitals Seidman Cancer Center.

Intermittent ADT Failed to Improve Survival in Metastatic Prostate Cancer
Helio/HemOnc Today - Apr 30, 2013
Perspective by Robert Dreicer, MD, FACP, FASCO...Long before prospective trial data was available, many clinicians embraced the concept of intermittent androgen deprivation therapy (ADT).


Breast Cancer 2013: Seeing the Future

Registration is open for Breast Cancer 2013: Seeing the FutureFriday, May 24 at the Doubletree by Hilton Cleveland East Beachwood.

This course has a focus on the future of breast cancer treatment and how research shapes our progress. Early detection of breast cancer and then managing all stages of the disease is a rapidly changing field that remains a challenge for primary care physicians, gynecologists and breast cancer specialists. Advances in cancer genetics and genomics are guiding more of our interventions. Recent advances have changed the practice of removing axillary lymph nodes, once a standard in breast cancer treatment. Male breast cancer is rare and involves a different paradigm than female breast cancer. You will have the opportunity to speak with male breast cancer survivors at this conference. All care providers will benefit from new understanding of how to support families of cancer patients.

Race for the Place- Join Our Team!

The Race for the Place, an event that benefits the Gathering Place, will be held Sunday, June 2 at Beachwood Place Mall. The Case CCC has created a team. Click here to join the team or to show your support by making a donation. Contact Gillian Todd for more information.

Impact of Genomics on Cancer Diagnosis and Treatment: Open Drug Policy Forum

The Case CCC, in partnership with five other Midwest comprehensive cancer centers, will convene a public forum on the emerging revolution in genetic testing known as precision or personalized medicine on Monday, June 10. Experts from the government, pharmaceutical and insurance industries, public health sector, and the cancer research community will participate in dynamic lectures and discussions to consider the complexities of integrating genetic testing into cancer care.

This forum is free and open to the public. Pre-registration is required:

Planned discussions include:

Keynote Address: How Genomics May Transform Cancer Care
Arul Chinnaiyan, MD, PhD

How to Validate Genomic Based Decision Making in Cancer
Moderator: Sanford Markowitz, MD, PhD
Panel Members: Carl Morrison, DVM, MD; Robert J. Penny, MD, PhD; Michael A. Tainsky, PhD

Implications for Public Policy-Discussion with Congressional Representatives and NCI/FDA
Moderator: Donald L. Trump, MD
Panel Members: James H. Doroshow, MD; Stanton L. Gerson, MD; Elizabeth A. Mansfield, PhD; Anthony Murgo, MD, MS; Richard Schilsky, MD; Mikkael Sekeres, MD, MS

Challenges for the FDA and CMS: Drug Approval and Reimbursement for Off-label Drug Use for Cancer Genetic Alteration
Moderator: Richard Schilsky, MD
Panel Members: James H. Doroshow, MD; Martine George, MD, MSc; Elizabeth A. Mansfield, PhD; Neal Meropol, MD; Anthony Murgo, MD, MS

Genomics and Drug Reimbursement: White Paper from the Cleveland Forum 2013
Moderator: Stanton L. Gerson, MD
Panel Members: Brian Bolwell, MD; Richard Schilsky, MD; Donald L. Trump, MD; Max S. Wicha, MD

Implementing Proper Use of Genomic Tests to Select Therapeutics
Moderator: Lyndsay Harris, MD
Panel Members: James H. Doroshow, MD, Candace S. Johnson, PhD; Patricia M. LoRusso, DO

More information is on the Cancer Center site.

Annual Scientific Retreat

The Annual Cancer Center Scientific Retreat will commence the evening of Thursday, July 11 with a speaker and reception in the Wolstein Research Building Auditorium. The Retreat will continue the next day, Friday, July 12, at Corporate College East. The agenda is still be finalized. Details will be circulated soon!


Mesothelioma Applied Research Foundation Research Grant Funding

The Mesothelioma Applied Research Foundation (Meso Foundation) is calling for applications for its 2013 round of mesothelioma research grant funding. The Meso Foundation offers research grants for two years up to $50,000 per year. Eligible projects may relate to benchwork, translational or clinical research that is not presently funded or pending review and may be conducted through any not-for-profit academic, medical or research institution.

Deadline: August 2


Harrington Discovery Institute Scholar-Innovator Grant Program
LOI Deadline: May 15
Application Deadline: August 2

NCI Provocative Questions
LOI Deadline: May 20
Applications Deadline: June 20

Ovarian Cancer Research Fund Program Project Development Grants
LOI Deadline: May 23
Application Deadline: August 23

Ovarian Cancer Research Fund Liz Tilberis Scholars Early Career Awards
LOI Deadline: May 23
Application Deadline: August 23

Ovarian Cancer Research Fund Ann Schreiber Mentored Investigator Award
LOI Deadline: May 23
Application Deadline: August 23

Lasker Clinical Research Scholars Program
LOI Deadline: May 24
Application Deadline: June 24

Lustgarten Foundation
Concept Deadline: May 24
Full Application Deadline: August 9

Chris4Life Colon Cancer Pilot Study Grant Program
Deadline: June 1

Ovarian Cancer Academy Award - Early-Career Investigator
Pre-Application Deadline: June 12
Application Deadline: August 28

Ovarian Cancer Research Program Pilot Award
Pre-Application Deadline: June 12
Application Deadline: August 28

Ovarian Cancer Research Program Teal Innovator Award
Pre-Application Deadline: June 12
Application Deadline: August 28

James S. McDonnell Foundation Postdoctoral Fellowship Award in Studying Complex Systems
Deadline: June 14

Request for Proposals for Pilot Collaborations with LMICs in Global Cancer Research or Global Health Research at NCI-Designated Cancer Centers‌
Deadline: June 14

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Notice of Correction to Application and Submission Information in PAR-13-201 Paul Calabresi Career Development Award for Clinical Oncology (K12)(NOT-CA-13-010)

Clarification of Review Process for Applications Submitted to PAR-11-210 Center for Inherited Disease Research (CIDR) High Throughput Genotyping and Sequencing Resource Access (X01)(NOT-HG-13-008)

Improvement of Animal Models and Development of Technologies for Stem Cell-Based Regenerative Medicine (SBIR)(R43/R44)(PA-13-223)

Improvement of Animal Models and Development of Technologies for Stem Cell-Based Regenerative Medicine (STTR)(R41/R42)(PA-13-224)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades!

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May 13

Pathology Research Seminar Series
Ryan Fecteau
PhD Candidate, Markowitz Lab, Pathology
Topic: GNAS Mutations Identify a Set of Right-sided, Ras Mutant, Villous Colon Cancers
12 pm WRB 1-413

Physiology and Biophysics Seminar
Joseph Wu, MD, PhD
Associate Professor, Cardiovascular Medicine and Radiology
Co–Director, Cardiovascular Institute
Stanford University 
Topic: iPSCs for Cardiac Disease Modeling and Drug Screening
4 pm SOM/Robbins Building, E-501

May 14

Cancer Pharmacology Training Program Symposium
Keynote Speaker: Mark Saltzman, PhD
Professor, Biomedical Engineering, Chemical & Environmental Engineering & Physiology
Yale University
Topic: Highly Penetrative Nanocarriers Loaded with Drugs Targeted to Resistant Cells Improve Treatment of Brain Tumors
10 am - 3 pm BRB 105

Immunology Seminar
Obondo Sande
PhD Candidate, Boom Lab, Pathology
Topic: Direct Regulation of CD4+ T Cell Function by Mycobacterium Tuberculosis Lipoarabinomannan (ManLAM)
12 pm WRB 1-413

Special Immunology Seminar Series
Rafick-Pierre Sékaly, PhD
Chief Scientific Officer and Co-Director
Vaccine and Gene Therapy Institute of Florida
Topic: Inflammation: Drivers and Consequences in Vaccines and HIV Infection
3 pm WRB 5-136

May 15

Hematology and Oncology Division Research Conference
Santosh Rao, MD 
Fellow, Div. of Hem/Onc
Topic: Research in Complementary Therapies in Oncology
8 am Lerner B-151

Immunology Seminar
Kelvin Lee
Professor and Chair, Immunology
Roswell Park Cancer Institute
Topic: Memories From the Time of Cholera
12 pm NC1-202 Cleveland Clinic

May 16

Cancer Trainee Seminar
Courtney Bartel
Graduate Student, Jackson Lab, Pathology
Topic: Regulation of FAM83A and FAM83B: Key Intermediaries in EGFR/RAS Signaling During Transformation 
Oana Paun, MD
Fellow, Div. Hem/Onc
Topic: Breast Cancer
12 pm WRB 3-136

Immunology Journal Club
Dixon Dorand
Graduate Student, Immunology
Topic: Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
12 pm WRB 5-136

Stem Cell Biology and Regenerative Medicine Seminar
Hongjun Song, PhD
Director, Stem Cell Program, Institute for Cell Engineering
Johns Hopkins University
Topic: Adult Hippocampal Neural Stem Cells
1 pm NE1-205 Cleveland Clinic

May 17

Hematology and Oncology Fellows Conference
Topic: TBD
8 am Wearn 137/Breen Conference Rm.

Taussig Cancer Institute Grand Rounds
Quynh-Thu Le, MD
Professor, Radiation Oncology
Stanford Cancer Institute
Topic: New Directions in the Management of Nasopharyngeal Carcinoma
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Robert J. Gillies, PhD
Chair, Cancer Imaging and Metabolism
Vice Chair, Radiology
H. Lee Moffitt Cancer Center
Topic: Causes & Consequences of Tumor Heterogeneity
12 pm BRB 105

Cancer Center Research in Progress
David N. Wald, MD, PhD
Assistant Professor, Pathology
Topic: Discovery of a Novel HdmX Inhibitor for Cancer
4 pm WRB 3-136

Case CCC Calendar

LRI Calendar


Breast Cancer 2013: Seeing the Future
May 24
Doubletree by Hilton Cleveland East Beachwood

Impact of Genomics on Cancer Diagnosis and Treatment: Open Drug Policy Forum
June 10
9 am - 3 pm Wolstein Research Building Auditorium
Draft Agenda

Annual Cancer Center Scientific Retreat
July 11-12


National GvHD Health Symposium
November 1