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April 1, 2013


Chemo Drug Shortages Put Patients at Risk of Death
Everyday Health - Mar 29, 2013
Stan Gerson, MD, director of University Hospitals Seidman Cancer Center..., said in the past his hospital has turned to outside facilities for help...

5 questions with … Communications Researcher, Relay For Life Honorary Chair Mary Step
Case Daily - Mar 29, 2013
When people hear the term "cancer research," they might think cures, genes or even prevention. Mary Step's studies take a different route.

Feds to Cut Medicare Payments for Cancer-fighting Gamma Knife, Thanks to Congress
Plain Dealer - Mar 28, 2013
Dr. Gene Barnett says the Cleveland Clinic hopes Congress will change its mind and pay the older, higher rates for the tumor-zapping device...The Gamma Knife's ability to direct cobalt radiation to an area as small as a millimeter makes it well-suited for the precision required of brain radiosurgery, says Dr. Mitch Machtay, chairman of radiation technology at University Hospitals Case Medical Center.

Genetic Markers For Cancer Risk Identified In Huge International Effort
Huffington Post - Mar 27, 2013
Dr. Charis Eng, chair of the Genomic Medicine Institute at the Cleveland Clinic, who didn't participate in the new work, called the breast cancer research exciting but not ready for routine use.

New Prostate Cancer Tests Could Reduce False Alarms
New York Times - Mar 26, 2013
"Even if we can only convince 15 to 20 percent of men that we have enough confidence that they don't need to be treated, that will be a big step forward," said Dr. Eric A. Klein of the Cleveland Clinic, who has worked with Genomic Health.

Copper Depletion Shows Early Success in Triple-negative Breast Cancer: Discoveries
Plain Dealer - Mar 18, 2013
Dr. Joseph Baar, director of breast cancer research and the Breast Cancer Survivor Program at University Hospitals Case Medical Center, said the concept is sound but it's much too soon to make any conclusions about TM's potential for triple-negative patients...


Conversations in Bioethics

Brock C. Reeve, MBA, Executive Director of the Harvard Stem Cell Institute, will highlight some of the recent scientific progress in the field of stem cell science and the accompanying ethical challenges facing us as individuals and as a society in his talk, Ethical Issues in Stem Cell Science – What People Aren't Talking About. Three hours of CREC are offered for this presentation on Thursday, April 18 at 12 pm in SOM E401. Please RSVP by Monday, April 15 to or call 216.368.0632. This presentation is sponsored by Kaiser Permanente Endowed Lectureship in Bioethics and co-sponsored by National Center for Regenerative Medicine, Department of Bioethics and Stem Cell Ethics Center at CWRU.

Case CCC Clinical Research Retreat

The 2013 Case CCC Clinical Research Retreat will take place Monday, April 22 from 5:30-7 pm in the Wolstein Research Building Auditorium. The agenda is still being finalized and will focus on scientific issues and initiatives. Please contact Drs. Smitha Krishnamurthi or Robert Dreicer, MD with any questions.

Case Gastrointestinal Cancers SPORE Retreat

Registration is open for the Case Gastrointestinal Cancer SPORE Retreat, scheduled for Friday, April 26 in Dively Rm. 202. The agenda is still being finalized, but discussion topics include Colon Cancer; Barrett's Esophagus; Cancer Metastasis; Cancer Prevention; and Cancer in Minorities. There will be a poster session at noon. All trainees and fellows are invited to submit poster abstracts to Dr. John Wang at by Monday, April 15. A cash prize will be awarded to the best poster.


Specialized Program of Research Excellence in Gastrointestinal Malignancies (GI SPORE)

All Faculty members are invited to submit outlines for pilot projects to be funded by the NIH P50 GI SPORE. Proposals must be submitted through CTSC Webgrants. Please note that a SPORE project must be directed toward translational research of a GI malignancy. At least one specific aim should involve either direct patient contact or the study of patient derived tissue samples.

More information on grant application is available at or through John Pounardjian,, 216.368.1976. Information is also posted on the CWRU GI SPORE website.

Deadline: April 1

Barrett's Esophagus Translational Research Network (BETRNet)

All Faculty members at participating institutions are invited to submit applications for Individual and/or Cross BETRNet pilot projectssubmit applications for Individual and/or Cross BETRNet pilot projects of up to $50,000 to be funded by the U54 BETRNet. Note that a BETRNet project must be directed toward translational research related to Barret's Esophagus. At least one specific aim should involve either direct patient contact or the study of patient derived tissue samples.

More information on grant application is available at or through Angele Latham,, 216.368.1674.

Deadline: May 10

Chris4Life Colon Cancer Pilot Study Grant Program

The Chris4Life Colon Cancer Foundation announces a program to fund pilot studies in colorectal cancer research. Our aim is to fund pilot and feasibility studies to help improve talented investigators' prospects for future long term funding. In 2013 we will give priority to proposals in the clinical and bioinformatics research fields.

Deadline: June 1

Computational Genomic Epidemiology of Cancer Postdoctoral Training Program

The Case CCC invites applications to its 2-3 year NCI-funded Computational Genomic Epidemiology of Cancer Postdoctoral Training Program. The program combines a mentored cancer research project designed by the fellow in collaboration with their mentors with a specialized curriculum of formal didactic training and individualized longitudinal curriculum.

This program is designed to prepare trainees for careers as independent investigators engaged in research at the intersection of cancer research, genetics, epidemiology, biostatistics and computer science. Cancer researchers obtaining training will have the skills vital to decipher the complex pathways comprising genetic and environmental risk factors for disease, and will ultimately be able to provide clinicians and their patients with valuable information for the prevention and treatment of cancer.

Candidates with an MD, PhD, or MD/PhD degree, strong quantitative skills, and an interest in a career in genetics research are encouraged to apply.


Skin Diseases Research Center Pilot and Feasibility (P&F) Program
Deadline: April 1

Call for Pilot Projects: Specialized Program of Research Excellence in Gastrointestinal Malignancies (GI SPORE)
Deadline: April 1

(LOI Deadline: February 18)
Application Deadline: April 5

Call for Pilot Projects: Barrett's Esophagus Translational Research Network (BETRNet)
Deadline: May 10

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

James S. McDonnell Foundation Collaborative Activity Awards
Deadline: Open

SAIC-Frederick Support of the Cancer Genome Atlas Program
Application Deadline: Open

Solving Kids' Cancer Therapeutic Development Initiative
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Functional Characterization of Oral Cancer Initiating Cells (R01)(RFA-DE-14-001)

Functional Characterization of Oral Cancer Initiating Cells (R21)(RFA-DE-14-002)

Innovative Research Methods: Prevention and Management of Symptoms in Chronic Illness (R01)(PA-13-165)

Innovative Research Methods: Prevention and Management of Symptoms in Chronic Illness (R15)(PA-13-166)

Innovative Research Methods: Prevention and Management of Symptoms in Chronic Illness (R21)(PA-13-167)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216.844.8317 phone
216.844.7832 fax


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April 1

Pathology Research Seminar Series
Steven Carrion
PhD Candidate, Pearlman Lab, Pathology
Topic: The RodA Hydrophobin on Aspergillus Fumigatus Spores Masks Dectin–1 and Dectin–2 Dependent Responses and Enhances Fungal Survival in Vivo
12 pm WRB 1-413

Cancer Center Faculty Candidate
Huiping Liu, MD, PhD
Assistant Professor, Ben May Department for Cancer Research
University of Chicago
Topic: MicroRNAs Regulate Breast Cancer Stem Cells, Metastasis and Drug Resistance
4 pm WRB 5-136

Physiology and Biophysics Seminar
James J. Chou, PhD
Professor, Biological Chemistry & Molecular Pharmacology
Harvard University
Topic: Molecular basis of UCP2 driven proton transport
4 pm SOM / Robbins Building, E-501

April 2

Radiation Oncology Grand Rounds
Louis Novak, MD
Assistant Professor, Radiation Oncology
Topic: Review of Mammosite Brachytherapy at LHUHSCC: Our 1st 3 years 2009-2012
8:10 am Lerner B-181

Immunology Seminar Series
Michael Katsnelson
PhD Candidate, Dubyak Lab, Pathology
Elane Reyes
PhD Candidate, Anthony Lab, Pathology
Topic: TBD
12 pm WRB 1-413

Medicine Grand Rounds
Arthur Slutsky, MD
Chief, Critical Care
University of Toronto
Vice President of Research
Michael's Hospital in Toronto
Topic: History of Mechanical Ventilation
12 pm Kulas Auditorium, Lakeside 5th Fl.

Special Cancer Center Seminar Series
In Kyoung Lim, MD, PhD
Professor, Biochemistry and Molecular Biology
Ajou University, Republic of Korea
Topic: Modes of Anticarcinogenic Activity of Tumor Suppressor, TIS21/BTG2/Pc3 Gene
2 pm BRB 105

April 3

Hematology and Oncology Division Research Conference
Topic: TBD
8 am Lerner B-151

Immunology Students/Fellows Research in Progress Seminar Series
Neetha Parameswaran
Post Doctoral Fellow, Gupta Lab, Immunology
Cleveland Clinic
Topic: Can Ezrin Regulate B Cell Activation in the Context of Autoimmunity?
Ling Wu
Graduate Student, Li Lab, Immunology
Cleveland Clinic
Topic: Skin Inflammation in Act1-Deficient Mice is T-Cell Intrinsic and Due to Exaggerated Th17 Derived IL-2
12 pm NC1-202 Cleveland Clinic

Case GI SPORE Seminar Series
Joseph E. Willis, MD
Associate Professor, Pathology
Topic: Colon Cancer Gene Mutations as Predictors of Clinical Outcomes
5:30 pm Lerner B-151

April 4

National Center for Regenerative Medicine Seminar
William H. Frey II, PhD
Director, Alzheimer's Research Center
Professor, Pharmaceutics and Oral Biology 
University of Minnesota/Regions Hospital
Topic: Intranasal Insulin, Drugs, Biopharmaceuticals and Stem Cells Bypass the Blood-brain Barrier to Treat Alzheimer's, Stroke, Parkinson's, Brain Tumors and Other CNS Disorders
9 am BRB 105

Immunology Journal Club
Hana Russo
Student, Immunology
Topic: CCR5 is a receptor for Staphylococcus aureus leukotoxin ED
12 pm WRB 5-136

Special Presentation: Parker Hannifin/Moss Professorship in Integrative Oncology Candidate
Ting Bao, MD
Assistant Professor, Medicine
University of Maryland
Topic: Integrating Acupuncture into Cancer Care
12 pm Breen Conference B405

April 5

Cancer Center Research in Progress canceled

Hematology and Oncology Fellows Conference
Topic: TBD
8 am Wearn 137/Breen Conference Rm.

Taussig Cancer Institute Grand Rounds
Sudipto Mukherjee, MD
Taussig Cancer Institute
Cleveland Clinic
Topic: From Fat Man to Lilliputian Seeds: The Unfolding Story of Radiation
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Shideng Bao, PhD
Associate Professor, Stem Cell Biology and Regenerative Medicine
CWRU/Cleveland Clinic
Topic: Cancer Stem Cells and Vascular Pericytes in Glioblastomas
12 pm BRB 105 

Case CCC Calendar

LRI Calendar


Breast Cancer Conference
May 17
Hilton Cleveland East

Annual Cancer Center Scientific Retreat
July 11-12


National GvHD Health Symposium
November 1