CASE CCC IN THE NEWS
Exercise May Cut Prostate Cancer in Whites, But Not Blacks
Everyday Health - Feb 8, 2013
But Timothy Gilligan M.D., a medical oncologist with the Cleveland Clinic in Ohio, says he is skeptical of the findings.
Tamoxifen May Have Long-term Benefits in Fighting Breast Cancer
Plain Dealer - Feb 4, 2013
"While you do get more side effects long term, the benefits significantly outweighed the side effects," said Dr. Rosemary Leeming, a surgical oncologist at University Hospitals... Because the ATLAS trial focused on a large patient population that was followed for a long period of time, oncologists probably will be very receptive to the findings, said Dr. G. Thomas Budd, a medical oncologist at the Cleveland Clinic Taussig Cancer Institute
Cancer Research by the Numbers
The Cancer Genome Atlas - Feb 6, 2013
Biostatistician Dr. Jill Barnholtz-Sloan strives to make a difference in the field of cancer research while inspiring her students at the same time. Learn more about how she uses TCGA data in her career in this TCGA in Action Researcher Profile.
Finke Receives NCI R01
Dr. Jim Finke was awarded an R01 from the National Cancer Institute to study the individual contributions of inflammatory proteins and their impact in promoting the activation and migration of highly active MDSC subsets, particularly those expressing the chemokine receptor CXCR2, with the hope that research findings may lead to new targets for therapeutic intervention.
Pizarro Receives Grant to Study Gastric Cancers
Dr. Theresa Pizarro, Associate Professor of Pathology and Medicine at CWRU, recently received a grant from the DeGregorio Family Foundation for her proposal, Role of the novel IL-1 family member, IL-33, in the gastritis-metaplasiacarcinoma sequence. Dr. Pizarro will work with Dr. Li Li, co-investigator, and Dr. Wei Xin, collaborator, on this project.
Tissue Microarray Survey
The Cancer Center is considering an initiative to build a series of Tissue Microarrays (TMAs) for member usage. We would like to assess the needs of our members so that we can start with the most feasible and useful TMAs. Please take this short survey regarding your research goals and needs.
December CTSC Core Utilization Pilot Awards
Congratulations to the recipients of the December CTSC Core Utilization Pilot Awards:
- Shu Chen, PhD: Identification of novel substrates of LRRK2, a Parkinson disease associated kinase
- Evren Gurkan-Cavusoglu, PhD: Analysis of the cell cycle dynamics for fludarabine or ABT-737 resistant Nalm-6 cells
- Youwei Zhang, PhD: Roles of long non-coding RNAs (lncRNAs) in DNA damage response
- Edward Medof, MD, PhD: Evidence for a plasma membrane complex containing C5a receptor (C5aR), IL-6-receptor (IL-6R), and vascular endothelial cell growth factor receptor-2 (VEGFR-2) that governs vascular endothelial cell (EC) viability and growth signaling
- Catherine Stein, PhD: Exploration of pathways underlying resistance to M. tuberculosis infection
Reminder: Registration of Studies in Clinicaltrials.gov and Reporting of Clinical Trial Results
Section 801 of the Food and Drug Administration Amendments Act (FDAAA 801) requires Responsible Parties to register and submit summary results of clinical trials with Clinicaltrials.gov. Clinical trial results registration became effective as of September 2008. The FDA is currently empowered to enforce the reporting requirements, as well as financial penalties on non-compliant investigators and institutions.
Clinical trial and result registration is centralized within the Case CCC, and April Firstencel, Case CCC Registration Coordinator, has been working with investigators, study staff and statisticians to ensure the Case CCC complies with federal requirements. This announcement serves as a reminder about our on-going efforts and the need for everybody's assistance and collaboration to meet these obligations. Please direct questions to April Firstencel, Case CCC Registration Coordinator for Clinicaltrials.gov, 216.286.2294, firstname.lastname@example.org.
American Association for Cancer Research
The AACR is accepting applications for the following funding opportunities:
- The Fight Colorectal Cancer-AACR Fellowship, in memory of Lisa Dubow represents a joint effort to encourage and support a postdoctoral or clinical research fellow to conduct translational or clinical research that focuses on novel therapeutic approaches for late-stage metastatic colorectal cancer. This grant will support a project designed to lead to individualized therapeutic options for treatment or the development of promising new cancer therapeutics for patients with metastatic colorectal cancer. Emphasis will be placed on proposed projects which will translate into clinical applications within a few year period, including those with predictive biomarker studies.
Deadline Extended: February 13
- The QuadW Foundation-AACR Fellowship for Clinical/Translational Sarcoma Research represents a joint effort to encourage and support a postdoctoral or clinical research fellow to conduct translational or clinical sarcoma research and to establish a successful career path in this field.
Deadline: February 19
- The AACR Clinical and Translational Cancer Research Fellowships are open to postdoctoral and clinical research fellows working at an academic, medical or research institution who will be in the first five years of their postdoctoral training at the start of the grant term. Proposed research projects may be in any area of clinical and/or translational cancer research.
Deadline: February 27
American Cancer Society IRG Awards
The Case CCC, with funds from its American Cancer Society Institutional Research Grant, will provide seed money to foster cancer research by junior faculty who have no current national grant support of their own. Investigators in the CWRU School of Medicine and Cleveland Clinic Lerner College of Medicine as well as in other schools and colleges in the University are eligible. Grants, not to exceed $30,000, will be awarded to investigators who intend to gather preliminary data to be used in seeking future and independently funded programs.
LOI Deadline: February 18
Application Deadline: April 5
Lymphoma Research Foundation
The Lymphoma Research Foundation (LRF) Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL), Follicular Lymphoma (FL) and Mantle Cell Lymphoma (MCL) Consortiums are seeking proposals for high quality research studies in the following three disease areas:
Applications to this initiative must include the study of primary CLL/SLL, FL or MCL patient samples to assure relevance to the human disease. In addition, applicants are required to explicitly delineate how the proposed research will incorporate collaborative interactions between/among investigators in different disciplines (e.g. pathology & medical oncology, basic science research & clinical investigators) and/or different institutions.
Deadline: February 19
MARK YOUR CALENDARS
Breast Cancer Program in Development Annual Retreat
Drs. William Schiemann and Lyndsay Harris, Co-Leaders of the Breast Cancer Program in Development, invite you to attend the program Annual Retreat on Monday, March 11from 9 am-3 pm in the Dively Building on CWRU campus. The agenda and program information will be available soon.
A melanoma mini-symposium is scheduled from 3-7 pm on Monday, March 11 in the Wolstein Research Building Auditorium. The purpose of this symposium is to provide a forum for physician scientists and biomedical researchers to foster communication and develop new collaborations on melanoma research. Please watch the newsletter for updates.
Annual Cancer Center Retreat
The Annual Cancer Center Scientific Retreat will commence the evening of Thursday, July 11 and continue through Friday, July 12. Location and agenda are still be finalized. Details will be posted in the newsletter in the coming months.