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2012 Articles

January 17, 2012

Date Released: 17 January 2012
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New Treatment May be Able to Give Some Cancer Patients More Time
WNDU-TV - Jan 13, 2012
Jorge A. Garcia, MD, Director Advanced Prostate Cancer Program Cleveland Clinic, explains how people need to talk about the new treatment, "I think it's a ...

Ohio Parents Admit Denying Ailing Son Medical Care
Bloomington Pantagraph - Jan 11, 2012
Dr. Stanton L. Gerson, director of the Case Comprehensive Cancer Center at Case Western Reserve University, said parents should watch for glands that are ...

Local Boy Chosen as St. Baldrick's Foundation Ambassador
Cleveland News Fox 8 - Jan 10, 2012
... so only accidents are more prevalent for causing death in children," said Dr. Jeff Auletta, Austin's doctor at University Hospitals. ...

Exploradio - The Other Side of Evolution
WKSU - Jan 9, 2012
Biochemist Nikki Harter specializes in how newly discovered micro-RNA plays a role in melanoma...


Cancer Center Seminar Series: Biomarker- Directed Therapy of NSCLC

Dr. David CarboneFriday, January 20
12 pm
BRB 105

Please join us Friday, January 20 for the next Cancer Center Seminar Series where Dr. David Carbone will present Biomarker- Directed Therapy of NSCLC.

Dr. Carbone is Professor of Medicine, Cell Biology, and Cancer Biology at the Vanderbilt University Medical Center, and Director of the Thoracic/Head and Neck Cancer Program at the Vanderbilt-Ingram Cancer Center. He is also Director and Principal Investigator of the Vanderbilt Specialized Program of Research Excellence (SPORE) in Lung Cancer and the Strategic Partnering to Evaluate Cancer Signatures UO1 consortium.

His research interests, grant support and publications have been focused on lung cancer, and specifically proteomic and expression array signature development, lung cancer genetics, cancer immunotherapy, tumor-associated immunosuppression mechanisms and gene therapy. Recent research directions include molecular profiling of lung cancers and preneoplasias, especially the use of mass spectrometry-based proteomics. He as over 150 peer-reviewed publications and review articles, has served on several NCI grant review panels, including the clinical program project parent committee, and has continuous NCI funding since early in his career. He has served on organizing committees for both ASCO and AACR and the Board of Scientific Counselors for the NCI, is currently Chair of the Lung Biology subcommittee for the Eastern Cooperative Oncology Group and on the Board of Directors of the International Association for the Study of Lung Cancer (IASLC).


Cooke Honored with Professorship

Dr. Kenneth R. CookeDr. Kenneth R. Cooke was recently honored as the Ohio Eminent Scholar for Stem Cell and Regenerative Medicine and the Dr. Leonard C. Hanna Professor at Case Western Reserve University School of Medicine. Dr. Cooke was recruited as the Ohio Eminent Scholar for Stem Cell and Regenerative Medicine in 2007 for his expertise in stem cell transplantation and the two most frequent and severe complications following this procedure: graft-versus-host disease (GVHD) and a frequently fatal form of lung disease known as idiopathic pneumonia syndrome (IPS). Dr Cooke also brings outstanding leadership to the University Hospitals Rainbow Babies and Children's Hospital blood and marrow transplant (BMT) program.

Case CCC Protocol Templates Mandatory By 1/1/2013

The Case CCC SOP protocol templates (short and long versions) are available on the Case CCC website at: They may also be accessed through links on the Clinical Research Portal or Clinical Trials Core Facility.

Effective immediately, protocol templates are considered a standard when developing investigator-initiated protocols which should contain all the necessary protocol template elements. Starting January 1, 2013, all investigators-initiated protocols will have to conform to the templates. Investigators are strongly encouraged to start using the templates as soon as possible and to provide feedback, so that the templates can be modified to better serve the needs of the Case CCC research community.

If you have any questions about the templates and/or to provide feedback, please contact Katarzyna Karelus at 216.844.4176 or

Message from Dr. Pamela Davis, Dean CWRU SOM

The University Hospitals "Legacy" publication for Winter, 2011-2012 states that the UH Seidman Cancer Center carries a "National Cancer Institute designation as a Comprehensive Cancer Center."

The UH Seidman Cancer Center does not have NCI designation as a Comprehensive Cancer Center. This designation, and the grant from the National Cancer Institute, comes to Case Western Reserve University.

The UH Seidman Cancer Center is part of the Case Comprehensive Cancer Center, as is the Taussig Cancer Institute at The Cleveland Clinic. Case Western Reserve University is proud of the region-wide collaboration we have achieved to advance research and discovery for patients in Northeast Ohio.


CTSC Annual Pilot Funding Competition

The Clinical and Translational Science Collaborative (CTSC) of CWRU and the Case Coulter Translational Research Partnership (CCTRP) is accepting letters of intent for 2012 CTSC Annual Pilot Grant Funding. The grant will fund up to $50,000 to support innovative translational research projects focused upon the invention, preclinical development and/or first in man studies of novel therapeutic agents, biomedical devices and diagnostics designed to address unmet clinical needs.

Investigators in the basic science and clinical departments at CWRU, Cleveland Clinic, MetroHealth Medical Center, UH and the Louis Stokes Cleveland VA Medical Center are eligible. The PI is required to be a faculty member from one of the five CTSC partner institutions and eligible to be a PI for an NIH grant.

Deadline Extended: January 17

St. Baldrick's Foundation

St. Baldrick's Foundations is accepting applications for itsSpring 2012 grant cycle through a limited submission process. Grants are offered in six funding categories for childhood cancer research:

  • St. Baldrick's Fellows: The Foundation funds years 2-3 of a pediatric oncology research fellowship, with an opportunity for one additional year of funding.
  • St. Baldrick's Scholars: This career development award is to help develop the independent research of highly qualified individuals still early in their careers.
  • Research grants: These one-year grants are for specific research projects which are hypothesis driven and may be either laboratory or clinical in nature.
  • Supportive Care Research grants: These are for specific research projects which are hypothesis driven and focus on areas related to the supportive care of children and adolescents with cancer.
  • Consortium Research grants: These grants are for consortium groups from multiple institutions to collaborate on specific research projects.
  • Sub-specialty Fellows: New for 2012, the foundation will fund salary and benefits for 1-2 years. These grants are for individuals trained in pediatric oncology, who wish to pursue training in a sub-specialty area

Internal Deadline: January 17
Mandatory LOI Deadline Due to Sponsor: January 31
External Application Deadline: April 6

Samuel Waxman Cancer Research Foundation: Individual Research Proposals

This year, the Samuel Waxman Cancer Research Foundation (SWCRF) will offer several two-year grants to individual investigators. Grantees will have the opportunity to extend their award to three years upon demonstration of successful collaborative efforts with existing members of the SWCRF Institute Without Walls. This RFA will focus on the pursuit of novel compounds, targets, and therapies.

Specific themes of interest to the SWCRF include studies that address:

  • aberrant gene regulation
  • transcriptional and signal transduction
  • epimutations
  • cell dormancy vs. proliferation

Internal Deadline: February 1
External Deadline: March 15

Case CCC Clinical Trials Protocol Specific Research Support Funding

The Case CCC is encouraging investigators to submit Letters of Intent for the Protocol Specific Research Support funding for Year 2012. The budgeted funds are for the conduct of early phase clinical trials and restricted to support research nurses and data managers directly involved in the conduct of these clinical trials. Studies developed jointly between UH and CCF with planned accrual at both institutions will be prioritized. Please direct questions and requests for information about the funding process to Katarzyna Karelus, Administrative Director, Case CCC Clinical Research Office, at 216.844.4176 or


January 10, 2012

Featured Article: Bevacizumab May Benefit Some Women with Ovarian Cancer

Use of Robotics May Not Reduce Side Effects of Prostate Cancer Surgery

Chemotherapy Associated with Microscopic Changes in the Brain

Drug Shows Promise against Hard-to-Treat Chronic Lymphocytic Leukemia

In Depth
Studies Raise Concerns about Partial-Breast Radiation Therapy

Featured Clinical Trial: Making Decisions about Cancer Prevention Medications for Breast Cancer

Physician Data Query Offers Authoritative Information for Cancer Patients and Professionals

Legislative Update





**All events are open to anyone interested in attending

January 16

January 17

Cancer Biology Seminar
Oliver Wessely, PhD
Associate Staff, Cell Biology, LRI
Cleveland Clinic
Topic: MicroRNAs and Polycystic Kidney Disease- Lessons from Mouse and Frog
11 am NC1-202 Cleveland Clinic

Berman Lecture/Department of Medicine Grand Rounds
Max Wicha, MD
Director, University of Michigan Comprehensive Cancer Center
Distinguished Professor of Oncology
Professor, Internal Medicine
University of Michigan
Topic: Clinical Implications of Cancer Stem Cells
12 pm Kulas Auditorium

Immunology Seminar Series
Brian Cobb, PhD
Assistant Professor, Pathology
Topic: Glycoimmunology: The Brave New World
12 pm WRB 1-413

January 18

Hematology and Oncology Division Research Conference
Afshin Dowlati, MD
Associate Professor, Medicine- Hem/Onc
Topic: New Insights in the Biology of Small Cell Lung Cancer
8 am Lerner Tower B-151

Immunology Faculty Research in Progress Series
Shiquang Qian, MD
Associate Staff, Immunology
Cleveland Clinic
Topic: Inflammation and Transplant Tolerance
12 pm NC1-202 Cleveland Clinic

OnCore Clinical Trials Management System Training Classes
Topic: General Information/Navigation, Searches, Home Screen Personalization
12 pm Wearn 137

January 19

Cancer Center/NCRM Special Seminar
Jacques Galipeau, MD
Professor, Hematology and Oncology, Pediatrics & Medicine
Emory University
Topic: Mesenchymal Stromal Cell Suppression of Autoimmune Response. From Discovery to Design of Cell Therapy Studies
12 pm Wearn 137

January 20

Hem/Onc Fellows Conference
Waqas Rehman, MD
Fellow, Division of Hematology and Oncology
Topic: EGFR in Breast Cancer
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Mark Levis, MD, PhD
Associate Professor, Oncology and Medicine- Hematologic Malignancies
Johns Hopkins University
Topic: FLT3/ITD AML: A Way to a Cure?
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
David Carbone, MD, PhD
Professor, Medicine, Cell Biology, and Cancer Biology
Vanderbilt-Ingram Cancer Center
Topic: Biomarker – Directed Therapy of NSCLC
12 pm BRB 105

Cancer Center Research in Progress Seminar
David Danielpour, PhD
Associate Professor, Div. of General Medical Sciences-Oncology
Topic: mTOR, Smads and Androgen Receptor in Prostate Cancer
4 pm WRB 3-316

Case CCC Calendar

LRI Calendar


Cancer Cell Signaling Program Retreat
February 29
6-8 at the College Club
RSVP to Tracy Rehl at


Department of Biomedical Engineering Special Seminar
May 3
Steve Zullo, PhD
Program Director, Division of Discovery Science and Technology
National Institute of Biomedical Imaging and Bioengineering, NIH
Topic: NIH Grant Machine Revealed, Not a Black Box Anymore
12 pm Wickenden 509

NCI Second Symposium on Translational Genomics
March 15-16
NIH, Bethesda, Maryland


Caring for Carcinoid Foundation-AACR Grants for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research
Deadline: January 17

Fight Colorectal Cancer-AACR Career Development Award, in memory of Lisa Dubow
Deadline: January 17

Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research
Deadline: January 18

Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine
Deadline: January 18

Robert Wood Johnson Foundation Executive Nurse Fellows
Deadline: January 18

Children's Tumor Foundation Young Investigator Award Program
Pre-Application Deadline: January 27
Application Deadline: April 2

National Center for Research Resources (NCRR) Shared Instrumentation Grant (SIG) Program
Internal LOI Deadline: January 27
External Deadline: March 21

Sarcoma Foundation of America (SFA)
Deadline: January 31

2012 Lasker Awards
Deadline: February 1

ASCO Conquer Cancer Foundation Merit Awards
Deadline: February 1

Oncology Nursing Foundation
Deadline: February 1

Lymphatic Research Foundation (LRF) Additional Support for NIH-funded F32 Postdoctoral Fellows
Deadline: February 3

Innovations for Health: Solutions that Cross Borders
Deadline: February 13

Advancing Health Services through System Modeling Research
Deadline: February 15

Leukemia Research Foundation New Investigator Grants
Deadline: February 15

Ohio Cancer Research Associates
Deadline: February 17

Robert Wood Johnson Foundation Clinical Scholars Program
Deadline: February 29

Leukemia & Lymphoma Society Translational Research Program
LOI Deadline: March 1
Full Application Deadline: March 15

Childhood Brain Tumor Foundation (CBTF)
Deadline: March 12

James S. McDonnell Foundation 21st Century Research Awards
Deadline: March 14

Damon Runyon-Sohn Pediatric Cancer Fellowship Award
Deadline: March 15

American Legacy Foundation Sybil G. Jacobs Award for Outstanding Use of Tobacco Industry Documents
Deadline: March 23

American Legacy Foundation Christine O. Gregoire Youth/Young Adult Award for Outstanding Use of Tobacco Industry Documents
Deadline: March 23

Irvington Institute Fellowship Program
Deadline: April 1

Wendy Will Case Cancer Fund
Deadline: April 1

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Pediatric Phase 1/Pilot Consortium (Limited Competition UM1)(RFA-CA-12-502)

Molecular Characterization of Salivary Gland Tumors (R01)(RFA-DE-12-011)

Molecular Characterization of Salivary Gland Tumors (R21)(RFA-DE-12-012)

Request for Information (RFI): U. S.-China Collaborative Cancer Research in Complementary and Alternative Medicine (NOT-CA-12-009)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


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