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2011 Articles

September 26, 2011

Date Released: 26 September 2011
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Stan Gerson, MD
Director, Case CCC

International Conference of the Society for Integrative Oncology (SIO)

The Society for Integrative Oncology meeting will be held November 10-12 in Cleveland. The SIO's approach of providing complimentary and fully integrated supportive oncology to practitioners and patients adds much value to patients, physicians, and hospitals.

This conference is an important event that pulls together international experts in the field, including keynote speaker Francis F. Collins, MD, PhD, Director of the National Institutes of Health. It is important the conference is well attended, and that the Case Comprehensive Cancer Center have a strong presence.

Please make every effort to register and attend.


Cleveland Clinic Specialists Mark Milestone in Prostate Cancer Treatment
PR Web (press release) - Sep 26, 2011
... that consider the risk of recurrence and optimal quality of life," said Eric Klein, MD, chairman of the Glickman Urological and Kidney Institute... and still allows for same-day planning and implantation," said radiation oncologist Jay Ciezki, M.D....

Technique Developed to Generate Myelinating Cell Progenitors for Drug Screening and Cell Therapeutics
Genetic Engineering News - Sep 26, 2011
Case Western's Paul J. Tesar, Ph.D., and colleagues, say the availability of pure populations OPCs will facilitate high-throughput screening approaches for ...

Cancer's Spread Confounds
Columbus Dispatch - Sep 25, 2011
Part of the answer could be in the genetic makeup of cancer cells, said Dr. Joseph Baar, director of breast-cancer research at University Hospitals Seidman ...

Protons: The Ultimate in Radiation Therapy
MD News (press release) - Sep 21, 2011
...protecting critical vital organs that are located right behind or adjacent to those tumors," explains Mitchell Machtay, MD, professor and chairman, Department of Radiation Oncology at UH ...

Ohio Third Frontier Gives Grants for Research in Medical Innovation in Cleveland
Plain Dealer - Sep 21, 2011
and treatment of breast cancer, said Dr. Donna Plecha, director of Breast Imaging and assistant professor..."A scan with better resolution may give us the ability to more reliably see if cancer is present without a biopsy," said project leader Raymond Muzic...


Cancer Center Seminar Series: Issues in the Use of Omics-Based Predictors in Clinical Trials – Notes from an NCI Workshop


Friday, September 30
12-1 pm
Frohring Auditorium - BRB 105

Please join us Friday, September 30 at the next Cancer Center Seminar Series featuring Mark Schluchter, PhD. Dr. Schluchter, Professor of Epidemiology and Biostatistics at CWRU and Associate Director for Biostatistics at the Case Comprehensive Cancer Center, will presentIssues in the Use of Omics-Based Predictors in Clinical Trials – Notes from an NCI Workshop. This talk was postponed from earlier this month.

Dr. Schluchter has been developing approaches and models for biomarker based clinical investigation. He attended the NCI workshop on this topic this summer, and will report on the consensus issues and recommendations that came from the conference. As a Cancer Center, we identified Biomarker informed clinical trials as our approach to personalized medicine in cancer investigation, with a goal of identifying appropriate treatments for specific patients. Dr. Schluchter will review the complexity of these issues, lessons learned and advise us how to do this better.

NCI Office of Cancer Centers Learning Series Webinar: Bringing Quantitative Imaging to Cancer Center Clinical Trials: The NCI's Quantitative Imaging Network (QIN)

The next NCI Office of Cancer Centers Learning Series Webinar, Bringing Quantitative Imaging to Cancer Center Clinical Trials: The NCI's Quantitative Imaging Network (QIN), will be Tuesday, October 4, at 2 pm. This presentation will address a new NCI initiative, the Quantitative Imaging Network (QIN). The goal of the program is to develop quantitative methods to predict and measure the response of cancer tumors to therapy using commercial imaging platforms. This presentation will provide information regarding the QIN program and demonstrate that it is rapidly becoming a resource for imaging data and metadata that can be leveraged by cancer centers in imaging research.

This webinar is free, but registration is required.


Pancreative Action Network-AACR Grants

The following grant opportunities are currently being offered by the American Association for Cancer Research (AACR).

Pancreatic Cancer Action Network-AACR Innovative Grants
The Innovative Grants support creative and cutting-edge ideas or approaches, including those successful in other areas of cancer that have justifiable promise for pancreatic cancer. These two-year grants, totaling $200,000, will be awarded to independent junior or senior investigators. It is anticipated that multiple grants will be funded.
LOI Deadline: October 3

Pancreatic Cancer Action Network-AACR Career Development Awards
The Career Development Award is a two-year grant totaling $200,000, which supports newly independent investigators develop or strengthen a research program in pancreatic cancer. 
Application Deadline: October 31

Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant
The Pathway to Leadership Grant is designed to build future leaders in the pancreatic cancer research community by supporting a highly promising early-career scientist in his/her postdoctoral or clinical research fellowship through the transition to an independent researcher. 
Application Deadline: October 31

Pancreatic Cancer Action Network-AACR Fellowship
This fellowship supports an early-career scientist during his/her mentored research phase. 
Application Deadline: October 31

University-Community Partnerships to Improve Urban Health Outcomes

CWRU SOM is offering small grants to address urban health issues through University-Community partnerships. Proposals should translate research findings in an effort to improve health conditions existing or are exacerbated through residence in a local distressed area; and/or increase the preparedness of providers to address urban health issues. Applications must reflect a partnership between a community organization and a CWRU faculty member. Applications are encouraged from CWRU-SOM students and faculty, and from faculty at other Case schools and colleges and affiliates. However, the PI must be a CWRU SOM faculty member.

Deadline: November 1

Kimmel Scholar and Translational Science Awards

The Sidney Kimmel Foundation for Cancer Research is accepting applications for the Kimmel Scholar and Translational Science Awards.

Kimmel Scholar Award
The Kimmel Foundation is seeking accomplished young investigators dedicated to a career in cancer research. Applications are limited to those who achieved the equivalent rank of Assistant Professor on or after July, 2008. However, physicians who have both clinical and research responsibility are eligible if appointed on or after July, 2007. These awards are designed for researchers who do not yet have their own R01 funding. Applicants will be judged on the basis of quality of prior work, research proposed and letters of support.

The Kimmel Translational Science Award
The Foundation provides up to five additional awards specifically for physicians engaged in translational science. Eligibility includes those with MD or equivalent degrees, who have achieved the rank of Assistant Professor on or after July, 2007. Candidates must not hold R01 funding for the laboratory component of their cancer research. Applicants must demonstrate a significant personal involvement in the laboratory component of the translational project described. The translational research may involve primarily animal studies but must include reasonable application to subsequent human investigation.

Deadline: December 1


September 20, 2011

Featured Article: HPV Vaccine Study in Costa Rica Yields Insights on Cancer Prevention

For Young Women, Breast Conserving Surgery May Be Acceptable Alternative to Mastectomy

Fluorescent Probe Helps Surgeons Find Ovarian Cancer Cells

Nurse Practitioners, Physician Assistants Could Alleviate Projected Oncology Workforce Shortage

Study Suggests How the BRCA1 Protein May Help Suppress Tumors

Bacterium Associated with Stomach Cancer Directly Damages DNA

A Conversation with Dr. Ted Trimble on NCI's Center for Global Health

In Depth
In Breast Cancer, Moving Toward More Personalized Hormone Therapies

Unpublished Phase III Cancer Trials: Eliminating the Negative?

Featured Clinical Trial: Studying the Natural Course of Precursor Conditions to Multiple Myeloma

Researchers Discuss State-of-the Science on Myelodysplastic Syndromes

FDA Update Update




**All events are open to anyone interested in attending

September 26

Pathology Research Seminar Series
Marcelo Jacobs-Lorena, PhD
Professor, Molecular Microbiology and Immunology
Johns Hopkins University
Topic: Fighting Malaria With Engineered Fungi and Bacteria
12 pm WRB 1-413

Skeletal Research Center Seminar
Donald Lennon, DDS
Senior Research Associate, Skeletal Research Center
Topic: Safety and Adventure
4 pm Millis 123

September 27

Cancer Biology Special Seminar
Fazlul Sarkar, PhD
Professor, Pathology
Wayne State University
Topic: Targeting miRNAs for Overcoming Therapeutic Resistance: Implication in Cancer Therapy
11 am NC1-202 Cleveland Clinic

Immunology Seminar Series
Nancy Maizels, PhD
Professor, Immunology and Biochemistry
University of Washington
Topic: Immunoglobin Gene Diversification: A Toolbox for Gene Correction and Therapy
12 pm WRB 1-413

September 28

Hematology and Oncology Research Conference
Topic: TBD
8 am Lerner B-151

Immunology Seminar
Thomas Hamilton, PhD
Professor and Chair, Immunology
CWRU/Cleveland Clinic
Topic: IL-17 and the Post-transcriptional Control of Chemokine Gene Expression
12 pm NC1-202 Cleveland Clinic

September 29

Molecular Genetics Seminar
Shunichi Takeda, MD, PhD
Kyoto University
Topic: Reverse Genetic Analysis of DNA Damage Response Using the Chicken DT40 B Cell Line
9:30 am NE1-205 Cleveland Clinic

Molecular and Microbiology Seminar
Yehong Huang
Jacobberger Lab, General Medical Sciences-Oncology
Topic: A Comparison of the Effect of B Cyclins on Mitotic Time and Endoduplication
James Jacobberger, PhD
Professor, General Medical Sciences- Oncology
Topic: Kinetic Expression Profiling and Mathematical Modeling of the Cell Cycle
1 pm SOM W203

September 30

Hematology/Oncology Fellows Conference
Topic: TBD
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Jeffrey Miller, MD
Professor, Medicine- Hematology, Oncology and Transplantation
University of Minnesota
Topic: Harnessing NK Cells in Cancer and Transplantation
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Mark Schluchter, PhD
Professor, Epidemiology and Biostatistics
Associate Director for Biostatistics, Case Comprehensive Cancer Center
Case Western Reserve University
Topic: Issues in the Use of Omics-Based Predictors in Clinical Trials – Notes from an NCI Workshop
12 pm BRB 105

Cancer Center Research in Progress
Cheng-Kui Qu, MD, PhD
Associate Professor, Medicine- Hem/Onc
Topic: Non-lineage/stage Restricted Effects of a Gain-of-function Mutation in Tyrosine Phosphatase Ptpn11 (Shp2) on Leukemia Stem/Initiating Cell Development
4 pm WRB 3-136

Case CCC Calendar

LRI Calendar


Graft Versus Host Disease Conference
November 4
Renaissance Cleveland Hotel, 24 Public Square, Cleveland


8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions
November 10-12
InterContinental Hotel Cleveland


AACR-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention
Deadline: September 26

AACR Award for Lifetime Achievement in Cancer Research
Deadline: September 26

AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research
Deadline: September 26

AACR Princess Takamatsu Memorial Lectureship
Deadline: September 26

Induced Pluripotent Stem Cell Pilot Research Awards
Deadline: September 30

Robert Wood Johnson Foundation Health & Society Scholars program
Deadline: September 30

Szent-Györgyi Prize for Progress in Cancer Research
Deadline: September 30

CTSC Nutrition Obesity Research Pilot Funding
Deadline: September 30

Burroughs Wellcome Fund Medical Scientist Career Awards
Deadline: October 1

Cancer Research Institute Irvington Institute Fellowship Program
Deadline: October 1

AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship
Deadline: October 11

AACR G.H.A. Clowes Memorial Award
Deadline: October 11

AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship
Deadline: October 11

AACR Award for Outstanding Achievement in Cancer Research
Deadline: October 11

AACR Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
Deadline: October 11

AACR Richard and Hinda Rosenthal Memorial Award
Deadline: October 11

Robert Wood Johnson Foundation Scholars in Health Policy Research program
Deadline: October 12

DOD PRCRP Discovery Award
Pre-Application Deadline: October 13
Application Deadline: October 27

DOD LCRP Concept Award
Pre-Application Deadline: October 19
Deadline: November 9

Oncology Nursing Society Oncology Nursing Health Policy and Advocacy Award
Deadline: October 31

DeGregorio Family Foundation for Gastric and Esophageal Cancer Research and Education
Deadline: November 1

Leukemia & Lymphoma Society Specialized Center of Research Program
Deadline: November 1

Friends of Jose Carreras International Leukemia Foundation (FJCILF) E.D. Thomas Postdoctoral Fellowship
Deadline: November 2

Robert Wood Johnson Foundation Health Policy Fellows program
Deadline: November 9

NCI Provocative Questions Project
Deadline: November 14

American Medical Association Seed Grant Research Program
Deadline: December 5

HHMI Medical Research Fellows Program
Deadline: January 11, 2012

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

James S. McDonnell Foundation Collaborative Activity Awards
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Notice of Correction to the Proposed Project Start and End Dates (Item 12; SF 424 R&R Cover Component) for the 2012 NIH Directors Pioneer Award Program (RFA-RM-11-004) (NOT-RM-11-026)

Mechanistic Pathways Linking Psychosocial Stress and Behavior (R01) (RFA-HL-12-037)

NIH Director's Transformative Research Awards (R01) (RFA-RM-11-006)

Interventions for Health Promotion and Disease Prevention in Native American Populations (R01)(PAR-11-346)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


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