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2011 Articles

October 10, 2011

Date Released: 10 October 2011
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Stan Gerson, MD
Director, Case CCC

Case Comprehensive Cancer Center and Case Western Reserve University Receive $5.4 Million Grant to Study Esophageal Cancer

Last week, the Case CCC announced the receipt of funding from the NCI to support the Barrett's Esophagus Translational Research Network (BETRNet). Researchers from multiple centers will collaborate to develop an understanding of the basis of Barrett's esophagus and its conversion to esophageal carcinoma. This is very exciting news for our Center, and speaks to the world-class group of researchers assembled by PI Dr. Amitabh Chak. This grant is the result of teamwork by researchers at the Case CCC, Johns Hopkins University, University of North Carolina at Chapel Hill, University of Pennsylvania, University of Washington/Fred Hutchinson Cancer Research Center, and Washington University in Saint Louis. Congratulations to everyone involved!


New Targets for Treating Inflammatory, Autoimmune Diseases Discovered
Science Daily - Oct 8, 2011
Discovery of this pathway was the work of an active collaboration between Xiaoxia Li, Ph.D., and Thomas Hamilton, Ph.D., Department Chair, ...

Insurers Review Whether to Still Pay for Routine Screening
New York Times - Oct 7, 2011
Dr. Eric Klein, head of urology at the Cleveland Clinic, said he remained a believer in PSA tests and would still encourage men without symptoms of prostate ...

Icing Bone Cancer
WKYC-TV - Oct 7, 2011
Dr. David Prologo inserts a probe into the bone using CAT and MRI scans to guide him to the exact spot of the cancer lesion. Then the probe freezes the ...

Video: Latest Technology in Diagnosing and Treating Prostate Cancer
WCSH Portland - Oct 7, 2011
Dr. Lee Ponsky from University Hospitals Case Medical Center talks about the latest innovations in diagnosing, treating and managing prostate cancer

New Research Shows PET Imaging Effective in Predicting Lung Cancer Outcomes - Oct 7, 2011
Mitch Machtay, MD, of the Seidman Cancer Center at University Hospitals (UH) Case Medical Center and principle investigator for the study, presented the ...

'Lost Boys' Have Found a New Home in Cleveland, but Haven't Forgotten Those Left Behind
Plain Dealer (blog) - Oct 5, 2011
Dr. Lee Ponsky started MedWish International, a Cleveland-based nonprofit, about 20 years ago when he was just 20 and wanted to change the world. ...


Cancer Center Seminar Series: Modeling the Genesis and Progression of Human Melanoma in the Mouse


Friday, October 14
12-1 pm
Frohring Auditorium - BRB 105

Please join us Friday, October 14 at the next Cancer Center Seminar Series featuring Glenn Merlino, PhD. Dr. Merlino, Chief of the Laboratory of Cancer Biology & Genetics and Deputy Director of the Center for Cancer Research at NCI, will present Modeling the Genesis and Progression of Human Melanoma in the Mouse.

Maximizing Resources to Effectively Recruit Participants for Research

Join the CWRU Office of Research Compliance Friday, October 28 from 8:30 am - 12 pm in the Wolstein Research Building Auditorium for a morning filled with the most current information available to enhance your research recruiting agenda. Experts will be on hand to provide practical guidance and share personal experiences. Sana Loue, JD, PhD, MPH, Associate Professor from CWRU's Bioethics and Epidemiology and Biostatistics Departments, will first discuss general recruitment strategies and methods. Next, Montana Miller, PhD, Assistant Professor of Popular Culture at Bowling Green State University, will outline the potential uses of social media strategies, including Facebook and Twitter, to enhance recruitment. Following the presentations, an expert panel of local researchers will be sharing their successes with various recruitment approaches. Pre-registration for this 6 CREC seminar is required.

Graft vs. Host Disease Conference

The Case CCC and the Meredith A. Cowden Foundation are bringing a national educational conference on Graft vs. Host Disease (GvHD) to Cleveland on Friday, November 4, 7:30 am to 5 pm, at the Renaissance Cleveland Hotel. The conference will unite leading specialists in hematology, oncology, bone marrow transplantation and immunology from more than a dozen of the nation's top cancer research centers and educational institutions to present information on cutting-edge research and treatments. Registration (includes CME credits), is $100 for physicians and pharmacists, $75 for nurses and other healthcare professionals and $25 for students. Please make every effort to register and attend.


AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research

The AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research provides funding to allow a meritorious young investigator to pursue an independent line of investigation within the context of his/her current fellowship placement. This grant provides a "bridge" between a training and an independent position, offering an opportunity for a young investigator to develop a new direction for his/her research program that otherwise may not have been possible in the absence of this funding.

Deadline: October 31

Urban Health Initiative (UHI) Pilot Grant

Pilot funds are available from CWRU SOM to address urban health issues through university-community partnerships. Proposals should use research to improve health conditions that exist or are exacerbated by living in a local distressed area and/or increase the preparedness of providers to address urban health issues. Applications are encouraged from SOM students and faculty as well as faculty from across campus; however, the PI must be a CWRU faculty member.

Deadline: November 1

Cellular Molecular Imaging of Cancer Pilot Funding: Cancer Microenvironment

The Case CCC is providing seed funding to develop a strong set of integrative cancer biology–molecular imaging projects that enhance interactions between clinical and basic science researchers with members of the Cancer Imaging Program. This funding will support investigative interdisciplinary teams with broad expertise in cancer biology, imaging science, pharmacology, or genetics with opportunities to explore aspects of cancer biology with non-invasive imaging technologies. Open to all Case, CCF and affiliate faculty members with a cancer or molecular imaging research track record.

See the RFA for more information.

Deadline: November 7

Rita Allen Foundation Scholars Program

CWRU has been invited to nominate ONE candidate for theRita Allen Foundation Scholars Program, which supports research scientists in the early stages of their careers in the fields of research in analgesics, cancer, immunology and neurosciences. Candidates must have completed their training and provided persuasive evidence of distinguished achievement or extraordinary promise in research in of the relevant fields.

Internal Deadline: November 14


Brady-Kalnay Receives Special Achievement Award

Dr. Susann Brady-Kalnay recently received the University of Dayton Alumni Special Achievement Award. Dr. Brady-Kalnay was recognized for her ground-breaking cancer research. Most recently, her research was featured on the cover of the September 1 issue of Cancer Research.

Jackson Publication Highlighted as "Top Story"

A publication by Dr. Mark Jackson and his research team was featured as the "Top Story" in the Mammary Cell e-news alert. The article, "c-MYC Functions as a Molecular Switch to Alter the Response of Human Mammary Epithelial Cells to Oncostatin M", was published October 5 online first in Cancer Research.

Keri Study Selected by F1000

A study conducted by Dr. Ruth Keri and Kristin Lozada, "Bisphenol A Increases Mammary Cancer Risk in Two Distinct Mouse Models of Breast Cancer" (Biol Reprod 2011 Sep 85 3:490-7), was highlighted by the peer-review service F1000, which places their work in a library of the top 2% of published articles in biology and medicine.

Importance of the OnCore Clinical Trials Management System Information for Cancer Center Support Grant Renewal

As we commence the Cancer Center Support Grant renewal period, it is critical that investigators and study staff ensure that research study information, including accrual data, is being entered into the OnCore database on an on-going basis. Accurate and timely information in OnCore forms a basis for our reporting capabilities for grant renewal purposes. Please make every effort to ensure that information on your studies in OnCore is complete.

Please contact April Firstencel 216-286-2294 with any questions regarding OnCore access, training and data entry.


October 4, 2011

Featured Article: Combination Therapy May Help Some Patients with Advanced Breast Cancer

Rising Oropharyngeal Cancer Rates Linked to HPV Infection

Hospitalization Following Prostate Biopsy Common in Older Men

Study Examines Sex Differences in Screening Colonoscopy Findings

Delivering Chemotherapy to the Liver May Benefit Patients with Metastatic Melanoma

Smoking Cessation Drug Proves Effective in Single-Center Trial

Also in the Journals: Zoledronic Acid May Benefit Postmenopausal Women with Breast Cancer

NCI's Office of Advocacy Relations: Bringing Advocacy and Research Together

A Conversation with Dr. Jane Perlmutter about the Role of Advocates in Cancer Research

In Depth
Workshop Examines Causes, Potential Remedies for Drug Shortages

Changing Face of Cancer in HIV-Positive Patients Requires New Approaches to Clinical Trials

Featured Clinical Trial: Testing Adjuvant Ipilimumab in Advanced Melanoma

NCI Director's Consumer Liaison Group Focuses on Improving Clinical Trials

FDA Update

NIH Update

Legislative Update Update




**All events are open to anyone interested in attending

October 10

Pathology Research Seminar Series: Harvey Werber Memorial Lecture
Betty Diamond, MD
Adjunct Professor, Microbiology & Immunology
Yeshiva University
Topic: Antibodies and the Brain: Lessons from Lupus
12 pm WRB 1-413

SDIG Meeting
Matthew Ruffalo
PhD Student, EECS
Topic: Split Alignment for Accurate Structural Variation Detection
2:30 pm WRB 1-402

Physiology and Biophysics Seminar
Mitchell Chesler, MD, PhD
Professor, Neurosurgery and Physiology and Neuroscience
Vice Chair of Research, Neurosurgery
New York University
Topic: Regulation and Modulation of Extracellular pH and Its Impact on Excitatory Synaptic Transmission
4 pm SOM E501

Skeletal Research Center
J. Michael Sorrell, PhD
Senior Research Associate, Skeletal Research Center, Biology
Topic: How to Make Fat in Culture
4 pm Millis 123

October 11

Cancer Biology Mid-Term Review Seminar
Haifeng Yang, PhD
Assistant Staff, Cancer Biology
Cleveland Clinic
Topic: Von Hippel- Lindau, Histone Modification and Kidney Cancer
10 am NC1-202 Cleveland Clinic

Immunology Seminar Series
John Harty, PhD
Endowed Chair in Microbial Immunology
Professor, Microbiology
University of Iowa
Topic: T Cell Responses and Immunity to Blood-Stage Malaria
12 pm WRB 1-413

October 12

Hematology and Oncology Division Research Conference
Paula Silverman, MD
Associate Professor, Medicine-Hem/Onc
Peter Oppelt, MD
Resident, Medicine
Topic: Patient Satisfaction on Inpatient Hematology and Oncology Services
8 am Lerner B-151

Immunology Visiting Professor Seminar Series
John Harty, PhD
Endowed Chair in Microbial Immunology
Professor, Microbiology
University of Iowa
Topic: What Are You Doing in My T Cell Memories?
12 pm NC1-202

Frontiers in Biological Sciences Lecture Series
Wei Gu, PhD
Professor, Pathology and Cell Biology
Columbia University
Topic: What Do We Really Know About p53?
4 pm SOM E301

October 13

October 14

Cancer Center Research in Progress Seminar canceled

Hematology/Oncology Fellows Conference
Nathan Langer, MD
Fellow, Div. of Hem/Onc
Topic: Oncology
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Stephanie Lee, MD
Fred Hutchinson Cancer Center
Topic: Chronic Graft-vs-Host Disease: Six Years After the NIH Consensus
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Glenn Merlino, PhD
Chief, Laboratory of Cancer Biology & Genetics
Deputy Director, Center for Cancer Research
National Cancer Institute, National Institutes of Health
Topic: Modeling the Genesis and Progression of Human Melanoma in the Mouse
12 pm BRB 105

Dental Medicine Seminar
Aaron Weinberg, DMD, PhD
Associate Professor and Chair, Biological Sciences
Associate Dean for Research, School of Dental Medicine
Topic: New Developments in Oral Cancer: When Too Much of a Good Thing is Bad!
2:30 pm WRB 5-136

Case CCC Calendar

LRI Calendar


Graft Versus Host Disease Conference
November 4
Renaissance Cleveland Hotel, 24 Public Square, Cleveland


8th International Conference of the Society for Integrative Oncology: Innovating Integrative Oncology: New Science, New Solutions
November 10-12
InterContinental Hotel Cleveland


AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship
Deadline: October 11

AACR G.H.A. Clowes Memorial Award
Deadline: October 11

AACR-Minorities in Cancer Research Jane Cooke Wright Lectureship
Deadline: October 11

AACR Award for Outstanding Achievement in Cancer Research
Deadline: October 11

AACR Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
Deadline: October 11

AACR Richard and Hinda Rosenthal Memorial Award
Deadline: October 11

Robert Wood Johnson Foundation Scholars in Health Policy Research program
Deadline: October 12

DOD PRCRP Discovery Award
Pre-Application Deadline: October 13
Application Deadline: October 27

DOD LCRP Concept Award
Pre-Application Deadline: October 19
Deadline: November 9

Oncology Nursing Society Oncology Nursing Health Policy and Advocacy Award
Deadline: October 31

Pancreatic Cancer Action Network-AACR Career Development Awards
Deadline: October 31

Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant
Deadline: October 31

Pancreatic Cancer Action Network-AACR Fellowship
Deadline: October 31

DeGregorio Family Foundation for Gastric and Esophageal Cancer Research and Education
Deadline: November 1

Leukemia & Lymphoma Society Specialized Center of Research Program
Deadline: November 1

Patient-Centered Outcomes Research Institute (PCORI) Pilot Projects Grants Program
LOI Deadline: November 1
Application Deadline: December 1

University-Community Partnerships to Improve Urban Health Outcomes
Deadline: November 1

Friends of Jose Carreras International Leukemia Foundation (FJCILF) E.D. Thomas Postdoctoral Fellowship
Deadline: November 2

Robert Wood Johnson Foundation Health Policy Fellows program
Deadline: November 9

NCI Provocative Questions Project
Deadline: November 14

Burroughs Wellcome Fund Collaborative Research Travel Grants
Deadline: December 1

Kimmel Scholar Award
Deadline: December 1

Kimmel Translational Science Award
Deadline: December 1

American Medical Association Seed Grant Research Program
Deadline: December 5

HHMI Medical Research Fellows Program
Deadline: January 11, 2012

Robert Wood Johnson Foundation Executive Nurse Fellows
Deadline: January 18, 2012

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

Case CCC Protocol Specific Research Support (PSRS)
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

International Waldenstrom's Macroglobulinemia Foundation (IWMF) Research Grant Program
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Translational Research at the Aging/Cancer Interface (TRACI) (R01) (PA-08-230)

Update of NIH Late Application Policy to Reflect Change in Due Dates for New Investigator R01 Resubmission Applications (NOT-OD-12-001)

Collaborations with National Centers for Biomedical Computing (R01) (PAR-12-001)

Produced by:
Gillian Irwin Todd
11100 Euclid Avenue, Wearn 149
Cleveland, Ohio 44106-5065
216-844-8317 phone
216-844-7832 fax


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