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2011 Articles

January 10, 2011

Date Released: 10 January 2011
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Communication Important When Facing Complex Medical Decisions - Jan 7, 2011
Barbara Daly, Ph.D., and Sara Douglas, Ph.D., the study's lead researchers from the Frances Payne Bolton School of Nursing at Case Western Reserve, ...


Damon Runyon Cancer Research Foundation Clinical Investigator Award

CWRU SOM has been invited to nominate up to three individuals for the Damon Runyon Cancer Research Foundation Clinical Investigator Award. This award supports young physician-scientists conducting patient-oriented cancer research, with a goal of increasing the number of physicians capable of moving seamlessly between the laboratory and the patient's bedside in search of breakthrough treatments.

New this year is a novel partnership with the National Institutes of Health (NIH) and the National Cancer Institute (NCI), which opens access to the NIH Clinical Center (CC) to Damon Runyon Clinical Investigators. The goal of this partnership is to use the special talent, expertise and resources of the participants to undertake pilot studies of specific diseases and to develop collaborative partnerships that accelerate clinical and translational cancer research, and thereby improve human health. See the website for more information.

If you are interested in applying for this award, please submit the following materials to by TODAY, Monday, January 10: biosketch and a one-paragraph description of how your research fits the description of "Clinical Research" as described by the Damon Runyon Foundation.

Internal Deadline: TODAY, January 10
External Deadline: March 1

Interinstitutional Basic, Clinical and Translational Research Projects in Cancer

The Case CCC will provide seed money to foster collaborations and promote and increase institution-wide capacity and competitiveness in basic, clinical or translational research that is aligned with the Cancer Center Scientific Programs and spans the institutions of the Case CCC. 2-3 awards of $75,000 - $100,000 will be made.

Faculty at all levels with interests in cancer research are encouraged to apply. Proposals require a minimum of two PIs: one from Case/UH and one from Cleveland Clinic. Proposals must involve new collaborative work with no joint publications or grants related to the current project. Applications will be submitted through

Deadline: January 18, 2011

Complete information is available on the Cancer Center website.


iMedRIS Training

New cancer research protocols requiring IRB review will be submitted, reviewed and stored electronically using the Case Cancer IRB electronic, web-based submission and review database provided by iMedRIS™ Data Corporation.

Part 4 (How to Respond to Stipulations) and Part 5 (How to submit Amendments) of the iMedRIS™ training sessions will be offered January through February. All interactive training will be accessible online using Adobe Acrobat Connect and telephone conference line and can be accessed at personal workstations.

For more information or to download training guides, please visit the iRIS Training Page. To register, please contact Mariesa Malinowski or Mark Tennant.

Shared Instrumentation Grant - DEXA Scanner

Message from Dr. Nathan Berger

As part of the Case CCC, we anticipate responding to NIH Shared Instrument Grant (S1O) PAR-11-081 with a request for a Dual-Energy X-ray Absorption (DEXA) Scanner. DEXA Scanning provides state-of-the-art technology for measurement of lean body-muscle mass, fat mass and bone density. We will apply for a patient level instrument and if enough interest exists, we will also apply for an instrument to perform the same measurements in small animals. Policy permitting, we are also considering applying for a Direct Segmental Multi-Frequency Bioelectrical Impedance Apparatus to perform repetitive measurements of body composition.

As you know, these awards are made to support the needs of groups of NIH funded investigators. Accordingly, I am requesting that any NIH funded investigators who anticipate using DEXA Scanning as a research tool notify me of their intent and send to me by January 20 a description of their research and need for these measurements (no more than 1 page), along with name, title and description of relevant NIH grant funding and an updated copy of your biosketch in NIH format. Please send all materials to

Please pass this email along to any other faculty member who might be interested. I would be happy to talk to anyone who wants further clarification.

Clinical Assay Development Program (CADP)

The NIH has recently unveiled a new program, the Clinical Assay Development Program (CADP), designed to provide support and expertise to aid in the transition of predictive or prognostic cancer research assays to clinically validated, robust, "CLIA-approved" assays. This program is similar in scope and design to the RAID program for drug development.

The assay to be developed must measure predictive or prognostic markers, assays measuring diagnostic markers will not be considered for this program. The primary biospecimens to be utilized will be archived, formalin fixed, paraffin embedded tissues, however, assays utilizing other biospecimens will be acceptable if they are sufficiently compelling. One important eligibility criterion requires that the assay must be able to be performed with instrumentation and techniques available in standard clinical labs.

The deadline for the first round of applications is January 21.

For additional information or to request assistance in development of an application, please contact: John Pink (, Director, Translational Research Core Facility, Case Comprehensive Cancer Center.


14th Annual Meeting of the Translational Research Cancer Centers Consortium 2011

The 14th Annual Meeting of the Translational Research Cancer Centers Consortium 2011 to be held at Seven Springs Mountain Resort, Seven Springs, PA on February 24-26. The goal of the conference is to gain a greater understanding of the interactions between the immune system and cancer in the setting of biologic therapy of cancer. This meeting is dedicated to the review of the newly-available biological agents and modes of their application, greater understanding of the modes of their action, potential for their synergistic and antagonistic effects, and the development of the optimal strategies for their clinical evaluation and eventual implementation as an integral part of comprehensive cancer care.

Planning committee members include Drs. Joseph Baar, Gregory Plautz, and Pierre Triozzi.

ISSCR 9th Annual Meeting

Registration is open for the International Society for Stem Cell Research (ISSCR) Annual Meeting, June 15-18 in Toronto, Canada. The ISSCR Annual Meeting has become the preeminent international stem cell meeting of the foremost stem cell professionals from public, private, academic and government settings. It provides a forum to promote and foster the exchange of research, featuring leading discoveries of the year and serving as a catalyst for stem cell research around the world.

Abstracts will be accepted through February 8. Abstract submission topics are available on the event website. Posters will be on display for the duration of the meeting.



**All events are open to anyone interested in attending

January 10

Physiology and Biophysics Seminar
Dennis Brown, PhD
Professor, Medicine
Harvard Medical School/ Massachusetts General Hospital
Topic: A Tale of Two Cell Types: New Insights into Proton Secretion and Water Reabsorption in the Kidney Collecting Duct
4 pm SOM E501

Cancer Imaging Nanotechnology Subgroup Meeting
4 pm Wearn B37

CCF / UH Urology Meeting
Topic: Discuss Collaborative Efforts Regarding the Management of Small Renal Masses / Localized RCC
5 pm Q1-202 Glickman Cleveland Clinic

January 11

Cancer Biology Fellow Seminar
Candece Gladson, MD
Professor, Cancer Biology
CWRU/ Cleveland Clinic
Topic: Anti-Angiogenic Therapy for Glioblastoma Tumors
11 am NC1-202 Cleveland Clinic

Taussig Cancer Institute Core Curriculum Series
Topic: Bioethics
12 pm R3-002 Cleveland Clinic

January 12

Hematology and Oncology Division Research Conference canceled

Immunology Visiting Professor Seminar Series
Leslie Berg, PhD
Professor, Pathobiology
University of Massachusetts
Topic: Regulation of T Cell Lineage Determination by the Tec Kinase, ITK
12 pm NC1-202 Cleveland Clinic

DNA Repair Inhibition Journal Club
John Pink, PhD
Assistant Professor, General Medical Sciences (Oncology)
Topic: What Can Salvage Do for You? The Effects of Extracellular Deoxynucleosides on DNA Repair and Survival in the Presence of Ribonucleotide Reductase Inhibition
2 pm SOM W331

January 13

Taussig Cancer Institute Core Curriculum Series
Roy Silverstein, MD
Professor, Cell Biology
CWRU/ Cleveland Clinic
Topic: Platelet Function
12 pm R3-002 Cleveland Clinic

Tumor Microenvironment and Metastasis Focus Group Meeting
1:30 pm WRB 3-136

January 14

Hematology/Oncology Special Conference
Mohamedtaki A. Tejani, MD
Fellow, Hematology and Oncology
Fox-Chase Cancer Center/Temple University
Topic: Pancreatic Cancer: A Pharmacogenomic Proposal
8 am Wearn 137

Taussig Cancer Institute Grand Rounds
Declan Walsh, MD
Solid Tumor Oncology
Cleveland Clinic
Topic: Symptom Clustering in Advanced Cancer
8 am R3/002-003 Cleveland Clinic

Cancer Center Seminar Series
Stathis Karathanasis, PhD
Assistant Professor, Biomedical Engineering
Topic: The Promise of Nanomedicine
12 pm BRB 105

Cell Biology Seminar Series
Michiko Watanabe, PhD
Professor, Pediatrics
Topic: Pluripotent Cells Within the Epicardium
3 pm NC1-202 Cleveland Clinic

Cancer Center Research in Progress Seminar
Kishore Guda, DVM, PhD
Research Instructor, Medicine- Hem/Onc
Topic: Non-coding and Coding RNAs as Biomarkers of Cancer Risk in Barrett's Esophagus
4 pm WRB 3-136

Case CCC Calendar

LRI Calendar


Breast Health Update: Issues for 2011
May 20
Hilton Cleveland East
Details to follow

8th International Conference of the Society for Integrative Oncology
November 10-12
InterContinental Hotel Cleveland
Details to follow


Active Living Research Annual Conference
February 22-24, 2011
San Diego, CA
Call for Abstracts Deadline: August 6

Multilevel Interventions in Health Care: Building the Foundation for Future Research Goals
March 4-5, 2011
Las Vegas, Nevada

4th Annual Biospecimen Research Network (BRN) Symposium: Advancing Cancer Research Through Biospecimen Science
March 28-29, 2011
Bethesda North Marriott Hotel & Conference Center in Bethesda, Maryland

2011 Clinical and Translational Research and Education Meeting: ACRT/SCTS Joint Annual Meeting
April 27-29, 2011
Omni Shoreham in Washington, DC
Abstract Deadline: December 16

Cancer Health Disparities Summit 2011
July 13-15, 2011
Bethesda North Marriott Hotel in Rockville, Maryland


Prostate Cancer Foundation (PCF) 2011 Creativity Awards
Deadline: January 13

Interinstitutional Basic, Clinical and Translational Research Projects in Cancer
Deadline: January 18

Avon Foundation Breast Cancer Research Program
Cycle 1 LOI Deadline: January 21
Cycle 1 Full Proposal Deadline: March 11

Prostate Cancer Foundation (PCF)-Honorable A. David Mazzone Special Challenge Award Research Program
Deadline: February 24

AICR Research Grant Program
External LOI Deadline: January 25
External Full Application Deadline: May 2

AICR Investigator Initiated Grants (IIGs)
LOI Deadline: January 25
Full Application Deadline: May 2

AICR Matching Grants
LOI Deadline: January 25
Full Application Deadline: May 2

AICR Postdoctoral Awards (PDAs)
LOI Deadline: January 25
Full Application Deadline: May 2

ACS Joseph S. Silber Student Research Fellowship
Deadline: January 28

2011 Lasker Medical Research Awards
Nomination Deadline: February 1 

2011 Jane Coffin Childs Memorial Fund for Medical Research Fellowship Awards
Deadline: February 1

Leukemia Research Foundation
Deadline: February 15

ACS Cancer Research Fellowship
Deadline: February 16

James S. McDonnell Foundation 21st Century Science Research Awards
Deadline: March 15

Avon Foundation Breast Cancer Research Program
Cycle 2 LOI Deadline: May 6
Cycle 2 Full Proposal Deadline: July 5

Translational Technology Concept Studies of Circulating Tumor and Endothelial Cells (CTC/CEC)
Deadline: Open

AACR Scholar-in-Training Awards - Other Conferences and Meetings
Deadline: Open

International Union Against Cancer (UICC) International Cancer Technology Transfer Fellowships
Application Deadline: Open

NCI Short-Term Scientist Exchange Program
Application Deadline: Open

James S. McDonnell Foundation Collaborative Activity Awards
Application Deadline: Open

NIH BULLETIN – Notices and Funding Opportunities

Implementation of Federal Financial Report Upcoming Mandatory Use of the Federal Financial Report System in the eRA Commons Beginning February 1, 2011 (NOT-OD-11-017)

Notice of Change in Agency Contact for PAR-10-137, Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R21) (NOT-OD-11-032)

Notice of Change in Agency Contact for PAR-10-136, Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R01) (NOT-OD-11-033)

NCI Will Participate in RFA-HG-11-003, Development of a Preliminary Evidence Base to Inform Decision-making about Returning Research Results to Participants in Genomic Studies (R01) (NOT-CA-11-005)


If you have a new grant, recently won an award, or have other newsworthy items, please let us know so we can publicize them in the newsletter and other media outlets. You deserve the accolades! Send items to Gillian Irwin at

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