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2011 Cancer Center News

Case Comprehensive Cancer Center and Case Western Reserve University Receive Prestigious Grant to Study Esophageal Cancer
October 6, 2011
The Case Comprehensive Cancer Center and Case Western Reserve University (CWRU) School of Medicine are proud to announce the receipt of a highly competitive $5.4 million grant to study genetic determinants of Barrett's esophagus and esophageal adenocarcinoma. This five-year award from the National Cancer Institute will support the Barrett's Esophagus Translational Research Network (BETRNet), which consists of multiple centers collaborating to develop an understanding of the basis of Barrett's esophagus and its conversion to esophageal carcinoma. Researchers will also work to determine the role genetics and environmental factors play in the development and progression of these diseases, with the ultimate goal of reducing the mortality associated with this deadly cancer.

Case Comprehensive Cancer Center Receives $11.3 Million to Establish GI SPORE- GI Cancers Research Center
September 16, 2011
The Case Comprehensive Cancer Center has been awarded an $11.3 million research grant to establish a GI SPORE- GI Cancers Research Center at Case Western Reserve University. With this designation, Case joins only six other nationally recognized GI SPORE Centers of Excellence in the country. Researchers from CWRU, University Hospitals Seidman Cancer Center and Cleveland Clinic, all members of the cancer center, collaborate in the research effort.

New Study Shows Blood Pressure Increase Indicates Treatment Response
April 29, 2011
Patients who develop high blood pressure while being treated for advanced kidney cancer with the drug sunitinib respond better to treatment, maintain longer progression-free survival, and survive longer, according to a Cleveland Clinic-led study.

The study, published today in The Journal of the National Cancer Institute, demonstrates that high blood pressure (hypertension) is a significant independent predictor of improved outcomes for patients with metastatic renal cell carcinoma....

Lack of sleep found to be a new risk factor for colon cancer
February 8, 2011
In a ground-breaking new study published in the Feb. 15, 2011 issue of the journal Cancer, researchers from University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine, found that individuals who averaged less than six hours of sleep at night had an almost 50 percent increase in the risk of colorectal adenomas compared with individuals sleeping at least seven hours per night. Adenomas are a precursor to cancer tumors, and left untreated, they can turn malignant...

Case CCC Members Named AAAS Fellows
February 7, 2011
In December 2010, 503 individuals were elected as Fellows of the American Association for the Advancement of Science (AAAS). The Case CCC is honored to have four members recognized for their contributions to science and technology: Drs. James Anderson for Engineering, Ram Ganapathi for Pharmaceutical Sciences, and Thomas Hamilton and Qing Wang for Medical Sciences. In addition, Dr. Eileen White, who has served on the Case CCC External Advisory Board since 2009, was also recognized for her work in the Medical Sciences.

New clinical trial to determine ovarian cancer risks in African-American women
February 1, 2011
University Hospitals Case Medical Center and Case Western Reserve University School of Medicine are conducting an important new study addressing the lack of knowledge about causes and risk factors for ovarian cancer in African American women. The five-year study is funded by the National Cancer Institute through Case Western Reserve University School of Medicine...

For more Cancer Center news, please see the Weekly Newsletter.