CASE COMPREHENSIVE
CANCER CENTER

ABOUT THE CASE COMPREHENSIVE CANCER CENTER

The Case Comprehensive Cancer Center (Case CCC) based at Case Western Reserve University (CWRU) is a partnership organization supporting all cancer related research efforts at CWRU, University Hospitals Case Medical Center, and the Cleveland Clinic. Located in Cleveland, Ohio, the Case CCC serves the cancer research and clinical needs of an urban manufacturing and rural agricultural region containing 3.8 million people in Northern Ohio.

The Mission of the Case Comprehensive Cancer Center is to:

• Improve the prevention, diagnosis and therapy of cancer through discovery, evaluation and dissemination.
• Stimulate and support innovative, coordinated interdisciplinary clinical research on cancer diagnosis, treatment, prevention and control.
• Develop clinical applications of discovery and make these available to Northern Ohio residents as quickly as possible through the integrated efforts of the major health systems in the region.
• Develop cancer prevention and control activities that build on the expertise of the Center and result in a reduction of cancer morbidity and mortality in Northern Ohio and the nation.

The Case CCC is organized into 9 interdisciplinary scientific programs plus one program initiative. There is a unified clinical research effort consisting of 11 Clinical Trials Disease Teams that develop and prioritize clinical trials between the partner institutions, and a single Protocol Review and Monitoring System, Data Safety and Monitoring Plan, and Institutional Review Board. These components serve to integrate cancer research, cancer therapeutics and prevention services at the partner institutions and throughout the region.

Research programs of the Case CCC are extending into Case affiliated hospitals including MetroHealth Medical Center (the region's county hospital), Louis Stokes Veterans Affairs Hospital, and 13 community medical centers operated by University Hospitals and Cleveland Clinic. The Center operates an NCI-supported Cancer Information Service (CIS) serving the Northern half of Ohio as part of the Midwest consortium and has an active outreach program for clinical practice-based prevention and screening initiatives, educational programs, minority recruitment and facilitation of patient referrals. Case CCC is a member of NCI's CaBIG initiative and is actively pursuing electronic databases for clinical trials, tissue repositories, and related bioinformatics.