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The Case Comprehensive Cancer Center (Case CCC) based at Case Western Reserve University (CWRU) is a partnership organization supporting cancer-related research efforts at CWRU, University Hospitals Case Medical Center, and Cleveland Clinic. Located in Cleveland, Ohio, the Case CCC serves the cancer research and clinical needs of an urban manufacturing and rural agricultural region containing 3.8 million people in Northern Ohio.

The Case CCC provides a unique forum and academic network for cancer researchers across our community to accomplish more than they may individually. Through the Case CCC, our medical institutions are linked in a stronger and more unified effort to understand the causes and progression of cancer and to use that understanding to develop treatments and to reduce the likelihood that our population will develop cancer and suffer from its consequences. The Cancer Center advocates for cancer research support across the institutions; provides funding for promising pilot grants, shared resource development, training programs, and recruitments; and catalyzes multidisciplinary and transdisciplinary cancer research across institutions, emphasizing innovative discovery that will have an impact on cancer patients.

The mission of the Case CCC is to:

  • Improve the prevention, diagnosis and therapy of cancer through discovery, evaluation and dissemination.
  • Stimulate and support innovative, coordinated interdisciplinary clinical research on cancer diagnosis, treatment, prevention and control.
  • Develop clinical applications of discovery and make these available to Northern Ohio residents as quickly as possible through the integrated efforts of the major health systems in the region.
  • Develop cancer prevention and control activities that build on the expertise of the Center and result in a reduction of cancer morbidity and mortality in Northern Ohio and the nation.

The research efforts of the Case CCC members are organized into eight interdisciplinary scientific programs. The clinical research effort is supported by 11 Clinical Trials Disease Teams that develop and prioritize clinical trials, and a single Protocol Review and Monitoring System, Data Safety and Monitoring Plan integrate cancer research, cancer therapeutics, and prevention services at the partner institutions and throughout the region.

Research programs of the Case CCC are also extending into community medical centers operated by University Hospitals and Cleveland Clinic. Outreach programs for clinical practice-based prevention and screening initiatives, educational programs, minority recruitment, and facilitation of patient referrals are also supported by the partner institutions.

In addition to successfully competing for a Cancer Center Support Grant from the National Cancer Institute, the Center must meet specific criteria for:

  • Breadth and depth of basic cancer research; clinical cancer research; and prevention, control and population/behavioral sciences research in cancer; and
  • Strength of interaction among these three major research areas.

The Case Comprehensive Cancer Center is one of only 41 NCI-designated Comprehensive Cancer Centers in the nation. Learn more about the National Cancer Institute’s Cancer Centers program at cancercenters.cancer.gov.